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Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group).

Basnyat B, Holck PS, Pun M, Halverson S, Szawarski P, Gertsch J, Steif M, Powell S, Khanal S, Joshi A, Shankar R, Karambay J, Alexander HD, Stone A, Morrissey C, Thompson BH, Farrar J. Spironolactone does not prevent acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial by SPACE Trial Group (spironolactone and acetazolamide trial in the prevention of acute mountain sickness group). Wilderness Environ Med. 2011 Mar; 22(1):15-22.

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