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Horacio Gomez-Acevedo

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiomedical Informatics, College of Medicine
Address ACH South Campus
501 Jack Stephens Drive
Mail Slot # 782
Little Rock AR 72205
Phone501-603-1766
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    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Academic Program Director DBMI

    Collapse education and training
    University of Alberta, Edmonton, Alberta CAPhD12/2005Applied Mathematics (Mathematical Biology)
    University of Arkansas at Little Rock, Little Rock, ARMS5/2011Bioinformatics

    Collapse Research 
    Collapse research activities and funding
    U01DD001306     (EL-HASSAN, NAHED)Sep 1, 2023 - Mar 31, 2027
    Centers for Disease Control & Prevention
    Birth Defects Study to Evaluate Pregnancy exposureS (BD-STEPS) Core– Arkansas Center
    Role: Principal Investigator
    2P20GM125503     (OBRIEN, CHARLES A)Apr 1, 2023 - Jun 30, 2028
    NIH/Nat. Inst. of General Medical Sciences
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Principal Investigator
    2P20GM125503-06     (OBRIEN, CHARLES A)Apr 1, 2023 - Jan 31, 2028
    NIH/Nat. Inst. of General Medical Sciences
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Principal Investigator
    U01DD001285     (NEMBHARD, WENDY N)Dec 1, 2018 - Aug 31, 2023
    NIH
    RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Palmieri M, Joseph TE, O'Brien CA, Gomez-Acevedo H, Kim HN, Manolagas SC, Ambrogini E. Retraction notice to "Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass" [Bone 170(2023) 116702]. Bone. 2023 11; 176:116885. PMID: 37633107.
      View in: PubMed
    2. Palmieri M, Joseph TE, O'Brien CA, Gomez-Acevedo H, Manolagas SC, Ambrogini E. Retraction: Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass. PLoS One. 2023; 18(8):e0290458. PMID: 37585400.
      View in: PubMed
    3. Dimori M, Pokrovskaya ID, Liu S, Sherrill JT, Gomez-Acevedo H, Fu Q, Storrie B, Lupashin VV, Morello R. A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation. Front Genet. 2023; 14:1204296. PMID: 37359363.
      View in: PubMed
    4. Palmieri M, Joseph TE, O'Brien CA, Gomez-Acevedo H, Kim HN, Manolagas SC, Ambrogini E. RETRACTED: Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass Bone. 2023 05; 170:116702. PMID: 36773885.
      View in: PubMed
    5. Ponte F, Kim HN, Warren A, Iyer S, Han L, Mannen E, Gomez-Acevedo H, Nookaew I, Almeida M, Manolagas SC. Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency. Sci Rep. 2022 06 17; 12(1):10257. PMID: 35715555.
      View in: PubMed
    6. Palmieri M, Joseph TE, O'Brien CA, Gomez-Acevedo H, Manolagas SC, Ambrogini E. Deletion of the scavenger receptor Scarb1 in osteoblast progenitors does not affect bone mass. PLoS One. 2022; 17(3):e0265893. PMID: 35349600.
      View in: PubMed
    7. Ronis MJJ, Gomez-Acevedo H, Shankar K, Hennings L, Sharma N, Blackburn ML, Miousse I, Dawson H, Chen C, Mercer KE, Badger TM. Soy Formula Is Not Estrogenic and Does Not Result in Reproductive Toxicity in Male Piglets: Results from a Controlled Feeding Study. Nutrients. 2022 Mar 07; 14(5). PMID: 35268101.
      View in: PubMed
    8. Palmieri M, Almeida M, Nookaew I, Gomez-Acevedo H, Joseph TE, Que X, Tsimikas S, Sun X, Manolagas SC, Witztum JL, Ambrogini E. Neutralization of oxidized phospholipids attenuates age-associated bone loss in mice. Aging Cell. 2021 08; 20(8):e13442. PMID: 34278710.
      View in: PubMed
    9. Palmieri M, Kim HN, Gomez-Acevedo H, Que X, Tsimikas S, Jilka RL, Manolagas SC, Witztum JL, Ambrogini E. A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice. J Bone Miner Res. 2021 01; 36(1):170-185. PMID: 32990984.
      View in: PubMed
    10. Gomez-Acevedo H, Dai Y, Strub G, Shawber C, Wu JK, Richter GT. Identification of putative biomarkers for Infantile Hemangiomas and Propranolol treatment via data integration. Sci Rep. 2020 02 24; 10(1):3261. PMID: 32094357.
      View in: PubMed
    11. Gomez-Acevedo H, Patterson JD, Sardar S, Gokden M, Das BC, Ussery DW, Rodriguez A. SMARC-B1 deficient sinonasal carcinoma metastasis to the brain with next generation sequencing data: a case report of perineural invasion progressing to leptomeningeal invasion. BMC Cancer. 2019 Aug 22; 19(1):827. PMID: 31438887.
      View in: PubMed
    12. Gomez-Acevedo H, Dornhoffer JR, Stone A, Dai Y, Richter GT. Gene Expression Differences in Pediatric Lymphatic Malformations: Size Really Matters. Lymphat Res Biol. 2018 08; 16(4):347-352. PMID: 30130159.
      View in: PubMed
    13. Ronis MJ, Gomez-Acevedo H, Shankar K, Sharma N, Blackburn M, Singhal R, Mercer KE, Badger TM. EB 2017 Article: Soy protein isolate feeding does not result in reproductive toxicity in the pre-pubertal rat testis. Exp Biol Med (Maywood). 2018 05; 243(8):695-707. PMID: 29763383.
      View in: PubMed
    14. Ronis MJ, Gomez-Acevedo H, Blackburn ML, Cleves MA, Singhal R, Badger TM. RNA-sequencing data analysis of uterus in ovariectomized rats fed with soy protein isolate, 17?-estradiol and casein. Data Brief. 2016 Jun; 7:1491-6. PMID: 27182546.
      View in: PubMed
    15. Ronis MJ, Gomez-Acevedo H, Blackburn ML, Cleves MA, Singhal R, Badger TM. Uterine responses to feeding soy protein isolate and treatment with 17?-estradiol differ in ovariectomized female rats. Toxicol Appl Pharmacol. 2016 Apr 15; 297:68-80. PMID: 26945725.
      View in: PubMed
    16. Shankar K, Kang P, Zhong Y, Borengasser SJ, Wingfield C, Saben J, Gomez-Acevedo H, Thakali KM. Transcriptomic and epigenomic landscapes during cell fusion in BeWo trophoblast cells. Placenta. 2015 Dec; 36(12):1342-51. PMID: 26515927.
      View in: PubMed
    17. Thakali KM, Saben J, Faske JB, Lindsey F, Gomez-Acevedo H, Lowery CL, Badger TM, Andres A, Shankar K. Maternal pregravid obesity changes gene expression profiles toward greater inflammation and reduced insulin sensitivity in umbilical cord. Pediatr Res. 2014 Aug; 76(2):202-10. PMID: 24819376.
      View in: PubMed
    18. Borengasser SJ, Kang P, Faske J, Gomez-Acevedo H, Blackburn ML, Badger TM, Shankar K. High fat diet and in utero exposure to maternal obesity disrupts circadian rhythm and leads to metabolic programming of liver in rat offspring. PLoS One. 2014; 9(1):e84209. PMID: 24416203.
      View in: PubMed
    19. Miousse IR, Sharma N, Blackburn M, Vantrease J, Gomez-Acevedo H, Hennings L, Shankar K, Cleves MA, Badger TM, Ronis MJ. Feeding soy protein isolate and treatment with estradiol have different effects on mammary gland morphology and gene expression in weanling male and female rats. Physiol Genomics. 2013 Nov 15; 45(22):1072-83. PMID: 24046281.
      View in: PubMed
    20. Borengasser SJ, Zhong Y, Kang P, Lindsey F, Ronis MJ, Badger TM, Gomez-Acevedo H, Shankar K. Maternal obesity enhances white adipose tissue differentiation and alters genome-scale DNA methylation in male rat offspring. Endocrinology. 2013 Nov; 154(11):4113-25. PMID: 23959936.
      View in: PubMed
    21. Miousse IR, Gomez-Acevedo H, Sharma N, Vantrease J, Hennings L, Shankar K, Cleves MA, Badger TM, Ronis MJ. Mammary gland morphology and gene expression signature of weanling male and female rats following exposure to exogenous estradiol. Exp Biol Med (Maywood). 2013 Sep; 238(9):1033-46. PMID: 23925648.
      View in: PubMed
    22. Saben J, Zhong Y, Gomez-Acevedo H, Thakali KM, Borengasser SJ, Andres A, Shankar K. Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity. Am J Physiol Endocrinol Metab. 2013 Jul 01; 305(1):E1-14. PMID: 23632636.
      View in: PubMed
    23. Ronis MJ, Sharma N, Vantrease J, Borengasser SJ, Ferguson M, Mercer KE, Cleves MA, Gomez-Acevedo H, Badger TM. Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity. Physiol Genomics. 2013 May 01; 45(9):351-66. PMID: 23482812.
      View in: PubMed
    24. Miousse IR, Gomez-Acevedo H, Sharma N, Vantrease J, Hennings L, Shankar K, Cleves MA, Badger TM, Ronis MJJ. Mammary Gland Morphology and Gene Expression Signature of Prepubertal Male and Female Rats Following Exposure to Exogenous Estradiol. Exp Biol Med. 2013.
    25. Shankar K, Borengasser SJ, Faske J, Kang P, Gomez-Acevedo H. Maternal obesity and post-natal high fat diet disrupt hepatic circadian rhythm in rat offspring. EB2013. 2013.
    26. Ronis M, Miousse IR, Sharma N, Vantrease J, Hennings L, Shankar K, Gomez-Acevedo H, Cleves M, Badger TM. Mammary gland morphology and gene expression signature of prepubertal male and female rats following exposure to exogenous estradiol. 52nd Annual Meeting & ToxExpo. 2013.
    27. Ronis MJ, Shankar K, Gomez-Acevedo H, Hennings L, Singhal R, Blackburn ML, Badger TM. Mammary gland morphology and gene expression differ in female rats treated with 17?-estradiol or fed soy protein isolate. Endocrinology. 2012 Dec; 153(12):6021-32. PMID: 23027806.
      View in: PubMed
    28. Shankar K, Zhong Y, Kang P, Blackburn ML, Soares MJ, Badger TM, Gomez-Acevedo H. RNA-seq analysis of the functional compartments within the rat placentation site. Endocrinology. 2012 Apr; 153(4):1999-2011. PMID: 22355068.
      View in: PubMed
    29. Zhang J, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Gomez-Acevedo H, Shankar K, Badger TM, Ronis MJ, Chen JR. Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-prubertal rat. Plos One. 2012; 7(4):e35736.
    30. Asghar S. J., Blossom S. J., Griebel M. L., Gomez-Acevedo H, Maham S. A., Melynk S., Williamson R., James S. J. Plasma Inflammatory and Oxidative Stress Markers in Autistic Children with Suspected Subclinical Seizures. Annals of Neurology. 2012.
    31. Andres A., Gomez-Acevedo H, Badger T. Quantitative Nuclear Magnetic Resonance to Measure Body Composition in Infants and Children. Obesity. 2011; 19(10):2089-95.
    32. Andres A, Gomez-Acevedo H, Badger TM. Quantitative nuclear magnetic resonance to measure fat mass in infants and children. Obesity (Silver Spring). 2011 Oct; 19(10):2089-95. PMID: 21779094.
      View in: PubMed
    33. Gomez-Acevedo H, Shankar K., Ronis M. J., Badger T. A methyl-seq analyses of rat offspring liver reveals maternal obesity-induced alterations in DNA methylation status at weaning. MidSouth Computational Biology and Bioinformatics Society Meeting. 2011.
    34. Asghar S. J., Griebel M. L., Williamson R., Blossom S. J., Maham S., Gomez-Acevedo H, James S. J. Identification of Subclinical Seizures in Children with Autism and their association with the Vineland Adaptive Behavioral Scales. International Meeting For Autism Research. 2011.
    35. Gilbert KM, Rowley B, Gomez-Acevedo H, Blossom SJ. Coexposure to mercury increases immunotoxicity of trichloroethylene. Toxicol Sci. 2011 Feb; 119(2):281-92. PMID: 21084432.
      View in: PubMed
    36. Gomez-Acevedo H, Li MY, Jacobson S. Multistability in a Model for CTL Response to HTLV-1 Infection and Its Implications to HAM/TSP Development and Prevention. Bulletin of Mathematical Biology. 2010; 72(3):681-696.
    37. Gomez-Acevedo H. A first encounter with viral illnesses modelling: the case of the HTLV-I virus (in Spanish). Miscelanea Matematica: a journal of the Mexican Mathematical Society. 2006; 42:91-106.
    38. Gomez-Acevedo H, Li MY. Backward bifurcation in a model of HTLV-I infection of CD4+ T cells. Bulletin of Mathematical Biology. 2005; 67:101-114.
    39. Gomez-Acevedo H. Global Stability in a model for diseases transmitted by ixodid ticks. Canadian Applied Mathematics Quarterly. 2003; 11:81-92.
    40. Gomez-Acevedo H, Li, M. Y. Global dynamics of a mathematical model for HTLV-I infection of T cells. Canadian Applied Mathematics Quarterly. 2002; 10:71-86.
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