Philip Palade
Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Pharmacology & Toxicology, College of Medicine |
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Division | Pharmacology Research |
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Address | B341-2 Biomedical Research II 200 South Cedar Mail Slot # 611 Little Rock AR 72202
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Phone | 501-526-4757 |
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vCard | Download vCard |
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Research R01HL095846 (PALADE, PHILIP T.)Jan 22, 2010 - Nov 30, 2014 NIH MicroRNA to decrease vascular CaV1.2 in hypertension Role: Principal Investigator |
| 09GRNT2110149 (PALADE, PHILIP T)Jul 1, 2009 - Jun 30, 2011 American Heart Association (South Central Affiliate) RNA interference to decrease vascular CaV1.2 in hypertension Role: Principal Investigator |
| R01HL073097 (PALADE, PHILIP T.)Dec 20, 2003 - Nov 30, 2008 NIH Cav1.2 Transcript Regulation in Heart and Smooth Muscle Role: Principal Investigator |
| R01HL063903 (PALADE, PHILIP T.)Sep 27, 2000 - Jul 31, 2007 NIH THE ALPHA-1C CALCIUM CHANNEL IN MUSCLE Role: Principal Investigator |
| R01AR041526 (PALADE, PHILIP T.)Sep 30, 1996 - Aug 31, 2002 NIH CA INDUCED CA RELEASE FROM STRIATED MUSCLE Role: Principal Investigator |
| R01AR043200 (PALADE, PHILIP T.)Jul 10, 1995 - Jun 30, 2000 NIH PHARMACOLOGY OF QUANTAL INTRACELLULAR CALCIUM RELEASE Role: Principal Investigator |
| R01HL042527 (PALADE, PHILIP T.)May 1, 1989 - Apr 30, 1994 NIH PHARMACOLOGY OF MUSCLE EXCITATION-CONTRACTION COUPLING Role: Principal Investigator |
| R01AR034377 (PALADE, PHILIP T.)Aug 1, 1984 - Sep 30, 1992 NIH CA RELEASE FROM SARCOPLASMIC RETICULUM: THE FROG PACKAGE Role: Principal Investigator |
| K04AM001347 (PALADE, PHILIP T.)Aug 1, 1984 - Jul 31, 1989 NIH CALCIUM RELEASE PROCESS OF SARCOPLASMIC RETICULUM Role: Principal Investigator |
| K04AR001347 (PALADE, PHILIP T.)Aug 1, 1984 - Jul 31, 1989 NIH CALCIUM RELEASE PROCESS OF SARCOPLASMIC RETICULUM Role: Principal Investigator |
| R01AM034377 (PALADE, PHILIP T.)Aug 1, 1984 - Jul 31, 1987 NIH CALCIUM RELEASE FROM ISOLATED SARCOPLASMIC RETICULUM Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Wang X, Liu L, Zhai L, Palade P, Wang X, Mehta JL. Direct Impact of PCSK9 on SMC Senescence and Apoptosis: A New Focus in Cardiovascular Diseases. Arterioscler Thromb Vasc Biol. 2024 07; 44(7):1491-1496. PMID: 38924434.
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Hindle A, Bose C, Lee J, Palade PT, Peterson CJ, Reddy PH, Awasthi S, Singh SP. Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels. Cancers (Basel). 2022 Jan 21; 14(3). PMID: 35158795.
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Bose C, Hindle A, Lee J, Kopel J, Tonk S, Palade PT, Singhal SS, Awasthi S, Singh SP. Anticancer Activity of O-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells. Cancers (Basel). 2021 Dec 20; 13(24). PMID: 34944997.
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Awasthi S, Hindle A, Sawant NA, George M, Vijayan M, Kshirsagar S, Morton H, Bunquin LE, Palade PT, Lawrence JJ, Khan H, Bose C, Reddy PH, Singh SP. RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease. Cells. 2021 11 10; 10(11). PMID: 34831336.
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Petkovic M, Leal EC, Alves I, Bose C, Palade PT, Singh P, Awasthi S, B?rsheim E, Dalgaard LT, Singh SP, Carvalho E. Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway. J Nutr Biochem. 2021 12; 98:108817. PMID: 34271100.
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Singh SP, Lee J, Bose C, Li H, Yuan YC, Hindle A, Singhal SS, Kopel J, Palade PT, Jones C, Rahman RL, Awasthi S. Haploinsufficiency Interactions between RALBP1 and p53 in ERBB2 and PyVT Models of Mouse Mammary Carcinogenesis. Cancers (Basel). 2021 Jul 02; 13(13). PMID: 34283045.
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Garner BR, Stolarz AJ, Stuckey D, Sarimollaoglu M, Liu Y, Palade PT, Rusch NJ, Mu S. KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema. J Pharmacol Exp Ther. 2021 01; 376(1):40-50. PMID: 33100270.
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Bose C, Alves I, Singh P, Palade PT, Carvalho E, B?rsheim E, Jun SR, Cheema A, Boerma M, Awasthi S, Singh SP. Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. Aging Cell. 2020 11; 19(11):e13261. PMID: 33067900.
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Jun SR, Cheema A, Bose C, Boerma M, Palade PT, Carvalho E, Awasthi S, Singh SP. Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice. Microorganisms. 2020 Sep 29; 8(10). PMID: 33003447.
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Bose C, Yadav S, Singhal SS, Singhal J, Hindle A, Lee J, Cheedella NKS, Rehman S, Rahman RL, Jones C, Darden M, Palade PT, Berz D, Singh SP, Awasthi S. Rlip Depletion Suppresses Growth of Breast Cancer. Cancers (Basel). 2020 Jun 02; 12(6). PMID: 32498332.
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Bose C, Singh SP, Igid H, Green WC, Singhal SS, Lee J, Palade PT, Rajan A, Ball S, Tonk V, Hindle A, Tarbox M, Awasthi S. Topical 2'-Hydroxyflavanone for Cutaneous Melanoma. Cancers (Basel). 2019 Oct 14; 11(10). PMID: 31615091.
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Dai Y, Palade P, Wang X, Mercanti F, Ding Z, Dai D, Mehta JL. High fat diet causes renal fibrosis in LDLr-null mice through MAPK-NF-?B pathway mediated by Ox-LDL. J Cardiovasc Pharmacol. 2014 Feb; 63(2):158-66. PMID: 24220312.
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Krishna A, Valderr?bano M, Palade PT, Clark JW. Rate-dependent Ca2+ signalling underlying the force-frequency response in rat ventricular myocytes: a coupled electromechanical modeling study. Theor Biol Med Model. 2013 Sep 10; 10:54. PMID: 24020888.
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Dai Y, Khaidakov M, Wang X, Ding Z, Su W, Price E, Palade P, Chen M, Mehta JL. MicroRNAs involved in the regulation of postischemic cardiac fibrosis. Hypertension. 2013 Apr; 61(4):751-6. PMID: 23381794.
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Krishna A, Valderr?bano M, Palade PT, Clark WJ. Multiphysics model of a rat ventricular myocyte: a voltage-clamp study. Theor Biol Med Model. 2012 Nov 21; 9:48. PMID: 23171697.
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Krishna A, Sun L, Valderr?bano M, Palade PT, Clark JW. Modeling CICR in rat ventricular myocytes: voltage clamp studies. Theor Biol Med Model. 2010 Nov 10; 7:43. PMID: 21062495.
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Wang W, Pang L, Palade P. Angiotensin II upregulates Ca(V)1.2 protein expression in cultured arteries via endothelial H(2)O(2) production. J Vasc Res. 2011; 48(1):67-78. PMID: 20639649.
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Wang W, Rhee SW, Mehta JL, Palade P. Vascular CaV1.2 expression is increased in atherosclerosis. 2010; 3621-Pos/B345.
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Wang W, Rhee SW, Chen C, Palade P, Mehta JL. Upregulation of the CaV1.2 expression in atherosclerosis. 2010; Peer Reviewed Abstract.
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Kang BY, Wang W, Palade P, Sharma SG, Mehta JL. Cardiac hypertrophy during hypercholesterolemia and its amelioration with rosuvastatin and amlodipine. J Cardiovasc Pharmacol. 2009 Oct; 54(4):327-34. PMID: 19687748.
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Pang, L., Sonkusare, S., Thakali, K., Melchert, R., Roberto, K., Palade, P. AAV-mediated vascular smooth muscle-specific knockdown of Cav1.2 as a long-term anti-hypertensive therapy. FASEB J. 23. 2009; 932.4.
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Wang WZ, Pang L, Palade P. Angiotensin II causes endothelial-dependent increase in expression of Ca(V)1.2 protein in cultured arteries. Eur J Pharmacol. 2008 Dec 03; 599(1-3):117-20. PMID: 18848828.
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Germinario E, Esposito A, Midrio M, Peron S, Palade PT, Betto R, Danieli-Betto D. High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+). Eur J Appl Physiol. 2008 Oct; 104(3):445-53. PMID: 18560877.
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Wang, W. Effects of Angiotensin II on CaV1.2 Expression in Mesenteric Artery. FASEB J. 2008; 22: 912.29.
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Pang, L.; Stimers, J.; Rhee, S. Smooth muscle specific knockdown of L-type calcium channel by exogenous microRNA (miRNA). FASEB J. 2008; 22: 912.32.
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Esposito A, Germinario E, Zanin M, Palade PT, Betto R, Danieli-Betto D. Isoform switching in myofibrillar and excitation-contraction coupling proteins contributes to diminished contractile function in regenerating rat soleus muscle. J Appl Physiol (1985). 2007 Apr; 102(4):1640-8. PMID: 17234797.
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Wang W, Machaca K, Marsh J, Palade P. Angiotensin II upregulates the expression of L-type calcium channels, inositol trisphosphate receptors and ryanodine receptors in rat mesenteric vascular bed. 2007; 21: A1156 (873.2).
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Palade P. The hunt for an alternate way to generate NAADP. Focus on "NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells". Am J Physiol Cell Physiol. 2007 Jan; 292(1):C4-7. PMID: 16899546.
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Wang WZ, Saada N, Dai B, Pang L, Palade P. Vascular-specific increase in exon 1B-encoded CAV1.2 channels in spontaneously hypertensive rats. Am J Hypertens. 2006 Aug; 19(8):823-31. PMID: 16876682.
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Sonkusare S, Palade PT, Marsh JD, Telemaque S, Pesic A, Rusch NJ. Vascular calcium channels and high blood pressure: pathophysiology and therapeutic implications. Vascul Pharmacol. 2006 Mar; 44(3):131-42. PMID: 16427812.
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Shi XZ, Pazdrak K, Saada N, Dai B, Palade P, Sarna SK. Negative transcriptional regulation of human colonic smooth muscle Cav1.2 channels by p50 and p65 subunits of nuclear factor-kappaB. Gastroenterology. 2005 Nov; 129(5):1518-32. PMID: 16285952.
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Germinario E, Esposito A, Zanin M, Palade PT, Betto R, Danieli-Betto D. Physiological characterization of 2-week regenerated soleus muscle fibers. 2005; Basic & Appl Myol 15:156.
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Saada NI, Carrillo ED, Dai B, Wang WZ, Dettbarn C, Sanchez J, Palade P. Expression of multiple CaV1.2 transcripts in rat tissues mediated by different promoters. Cell Calcium. 2005 Apr; 37(4):301-9. PMID: 15755491.
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Wang, W.-Z. Hypertensive SHR rat blood vessels express more exon 1b-encoded CaV1.2 channels than their WKY counterparts. Biophys. J. 2005; 88: 276a-277a.
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Winston J, Wang W, Yin H, Choksi D, Medley D, Palade P, Pasricha PJ. NGF induces sensitization of the vanilloid receptor (TRPV1) response in sensory neurons in acute pancreatitis by recruiting silent nociceptors. Gastroenterology. 2005; 128 (Supp 2): A-86.
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Saada N, Dai B, Echetebu C, Sarna SK, Palade P. Smooth muscle uses another promoter to express primarily a form of human Cav1.2 L-type calcium channel different from the principal heart form. Biochem Biophys Res Commun. 2003 Feb 28; 302(1):23-8. PMID: 12593842.
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Cavalli AL, O'Brien NW, Barlow SB, Betto R, Glembotski CC, Palade PT, Sabbadini RA. Expression and functional characterization of SCaMPER: a sphingolipid-modulated calcium channel of cardiomyocytes. Am J Physiol Cell Physiol. 2003 Mar; 284(3):C780-90. PMID: 12421694.
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Dai B, Saada N, Echetebu C, Dettbarn C, Palade P. A new promoter for alpha1C subunit of human L-type cardiac calcium channel Ca(V)1.2. Biochem Biophys Res Commun. 2002 Aug 16; 296(2):429-33. PMID: 12163037.
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Fan JS, Palade P. Preferential loss of EC coupling gradation at positive membrane potentials in rat ventricular myocytes. Pflugers Arch. 2002 Aug; 444(5):654-62. PMID: 12194019.
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Fan JS, Palade P. Effects of FPL 64176 on Ca transients in voltage-clamped rat ventricular myocytes. Br J Pharmacol. 2002 Mar; 135(6):1495-504. PMID: 11906963.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2002 | 4 | 2003 | 1 | 2005 | 5 | 2006 | 3 | 2007 | 2 | 2008 | 4 | 2009 | 2 | 2010 | 4 | 2012 | 1 | 2013 | 2 | 2014 | 1 | 2019 | 1 | 2020 | 4 | 2021 | 4 | 2022 | 1 | 2024 | 1 |
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