 Precursor Cell Lymphoblastic Leukemia-Lymphoma
"Precursor Cell Lymphoblastic Leukemia-Lymphoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Descriptor ID |
D054198
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| MeSH Number(s) |
C04.557.337.428.600 C15.604.515.560.600 C20.683.515.528.600
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| Concept/Terms |
Precursor Cell Lymphoblastic Leukemia-Lymphoma- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Precursor Cell Lymphoblastic Leukemia Lymphoma
- Leukemia, Acute Lymphoblastic
- Acute Lymphoblastic Leukemia
- Leukemia, Lymphoblastic
- Leukemia, Lymphoblastic, Acute
- Lymphoma, Lymphoblastic
- Leukemia, Lymphoid, Acute
- Lymphoblastic Leukemia
- Lymphoblastic Leukemia, Acute
- Lymphoblastic Lymphoma
- Lymphocytic Leukemia, Acute
- Acute Lymphocytic Leukemia
- Leukemia, Acute Lymphocytic
- Acute Lymphoid Leukemia
- Leukemia, Acute Lymphoid
- Lymphoid Leukemia, Acute
- Leukemia, Lymphocytic, Acute
Leukemia, Lymphocytic, Acute, L1- Leukemia, Lymphocytic, Acute, L1
- Lymphocytic Leukemia, L1
- L1 Lymphocytic Leukemia
- Leukemia, L1 Lymphocytic
- Lymphoblastic Leukemia, Acute, Childhood
- Lymphoblastic Leukemia, Acute, L1
- ALL, Childhood
- Childhood ALL
- Leukemia, Lymphoblastic, Acute, L1
Leukemia, Lymphocytic, Acute, L2- Leukemia, Lymphocytic, Acute, L2
- Lymphocytic Leukemia, L2
- L2 Lymphocytic Leukemia
- Leukemia, L2 Lymphocytic
- Lymphoblastic Leukemia, Acute, Adult
- Lymphoblastic Leukemia, Acute, L2
- Leukemia, Lymphoblastic, Acute, L2
- Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
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Below are MeSH descriptors whose meaning is more general than "Precursor Cell Lymphoblastic Leukemia-Lymphoma".
Below are MeSH descriptors whose meaning is more specific than "Precursor Cell Lymphoblastic Leukemia-Lymphoma".
This graph shows the total number of publications written about "Precursor Cell Lymphoblastic Leukemia-Lymphoma" by people in UAMS Profiles by year, and whether "Precursor Cell Lymphoblastic Leukemia-Lymphoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2025 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 | | 2023 | 3 | 0 | 3 | | 2022 | 2 | 1 | 3 | | 2021 | 5 | 1 | 6 | | 2020 | 2 | 1 | 3 | | 2019 | 4 | 1 | 5 | | 2017 | 3 | 2 | 5 | | 2016 | 3 | 0 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 4 | 1 | 5 | | 2013 | 2 | 1 | 3 | | 2011 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2005 | 1 | 2 | 3 | | 2004 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 1995 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 |
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Below are the most recent publications written about "Precursor Cell Lymphoblastic Leukemia-Lymphoma" by people in Profiles over the past ten years.
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Rahmatallah Y, Glazko G. Improving data interpretability with new differential sample variance gene set tests. BMC Bioinformatics. 2025 Apr 14; 26(1):103.
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Aminov S, Giricz O, Melnekoff DT, Sica RA, Polishchuk V, Papazoglu C, Yates B, Wang HW, Sahu S, Wang Y, Gordon-Mitchell S, Leshchenko VV, Schinke C, Pradhan K, Aluri S, Sohn M, Barta SK, Agarwal B, Goldfinger M, Mantzaris I, Shastri A, Matsui W, Steidl U, Brody JD, Shah NN, Parekh S, Verma A. Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency. J Clin Invest. 2024 Feb 20; 134(8).
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McNerney KO, Moskop A, Winestone LE, Baggott C, Talano JA, Schiff D, Rossoff J, Modi A, Verneris MR, Laetsch TW, Schultz L. Practice Preferences for Consolidative Hematopoietic Stem Cell Transplantation Following Tisagenlecleucel in Children and Young Adults with B Cell Acute Lymphoblastic Leukemia. Transplant Cell Ther. 2024 Jan; 30(1):75.e1-75.e11.
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Gandy K, Sapkota Y, Scoggins MA, Jacola LM, Koscik TR, Hudson MM, Pui CH, Krull KR, van der Plas E. Genetic variants, neurocognitive outcomes, and functional neuroimaging in survivors of childhood acute lymphoblastic leukemia. JNCI Cancer Spectr. 2023 07 03; 7(4).
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Schichman SA, Penton AL, Ghanta SN, Konda M, Papenhausen PR. B-lymphoblastic leukemia/lymphoma with MYC and BCL2 gene rearrangements shows evidence for clonal evolution and mitotic recombination. J Hematop. 2023 Jun; 16(2):111-117.
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Helman SR, Singh ZN. B-acute lymphoblastic leukemia with eosinophilic inclusions. Blood. 2023 03 30; 141(13):1645.
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Delgado M, Rainwater RR, Heflin B, Urbaniak A, Butler K, Davidson M, Protacio RM, Baldini G, Edwards A, Reed MR, Raney KD, Chambers TC. Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways. J Biol Chem. 2022 06; 298(6):101939.
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Al Hadidi S, Schinke C, Thanendrarajan S, Zangari M, van Rhee F. Enrollment of Black Participants in Pivotal Clinical Trials Supporting US Food and Drug Administration Approval of Chimeric Antigen Receptor-T Cell Therapy for Hematological Malignant Neoplasms. JAMA Netw Open. 2022 04 01; 5(4):e228161.
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Gandy K, Scoggins MA, Phillips N, van der Plas E, Fellah S, Jacola LM, Pui CH, Hudson MM, Reddick WE, Sitaram R, Krull KR. Sex-Based Differences in Functional Brain Activity During Working Memory in Survivors of Pediatric Acute Lymphoblastic Leukemia. JNCI Cancer Spectr. 2022 03 02; 6(2).
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Nguyen M, Naeem F, Razzaqi F, Vijayan V. Invasive Trichosporonosis in a 2-Year-old With Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2021 Nov 01; 43(8):e1254-e1255.
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Al-Kaylani HM, Reasoner EE, Loeffler BT, Mott SL, Madasu S, Liu A, Langbehn K, Conrad AL, Dickens D, Grafft A, Harshman L, Modi AJ, van der Plas E. Characterizing academic performance in pediatric acute lymphoblastic leukemia with population-based achievement tests. Cancer Rep (Hoboken). 2022 09; 5(9):e1560.
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Zhang XH, Chen J, Han MZ, Huang H, Jiang EL, Jiang M, Lai YR, Liu DH, Liu QF, Liu T, Ren HY, Song YP, Sun ZM, Tang XW, Wang JM, Wu DP, Xu LP, Zhang X, Zhou DB, Huang XJ. The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation: 2021 update. J Hematol Oncol. 2021 09 15; 14(1):145.
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Bauer HK, Malone MP. ECMO Support in Pre-B-Cell ALL for Disseminated Legionnaire's Disease. J Extra Corpor Technol. 2021 Sep; 53(3):204-207.
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van der Plas E, Qiu W, Nieman BJ, Yasui Y, Liu Q, Dixon SB, Kadan-Lottick NS, Weldon CB, Weil BR, Jacola LM, Gibson TM, Leisenring W, Oeffinger K, Hudson MM, Robison LL, Armstrong GT, Krull KR. Sex-Specific Associations Between Chemotherapy, Chronic Conditions, and Neurocognitive Impairment in Acute Lymphoblastic Leukemia Survivors: A Report From the Childhood Cancer Survivor Study. J Natl Cancer Inst. 2021 05 04; 113(5):588-596.
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van der Plas E, Modi AJ, Li CK, Krull KR, Cheung YT. Cognitive Impairment in Survivors of Pediatric Acute Lymphoblastic Leukemia Treated With Chemotherapy Only. J Clin Oncol. 2021 06 01; 39(16):1705-1717.
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van der Plas E, Spencer Noakes TL, Butcher DT, Weksberg R, Galin-Corini L, Wanstall EA, Te P, Hopf L, Guger S, Hitzler J, Schachar RJ, Ito S, Nieman BJ. Cognitive and behavioral risk factors for low quality of life in survivors of childhood acute lymphoblastic leukemia. Pediatr Res. 2021 08; 90(2):419-426.
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Lehrnbecher T, Fisher BT, Phillips B, Beauchemin M, Carlesse F, Castagnola E, Duong N, Dupuis LL, Fioravantti V, Groll AH, Haeusler GM, Roilides E, Science M, Steinbach WJ, Tissing W, Warris A, Patel P, Robinson PD, Sung L. Clinical Practice Guideline for Systemic Antifungal Prophylaxis in Pediatric Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients. J Clin Oncol. 2020 09 20; 38(27):3205-3216.
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Urbaniak A, Jousheghany F, Pi?a-Oviedo S, Yuan Y, Majcher-Uchanska U, Klejborowska G, Moorjani A, Monzavi-Karbassi B, Huczynski A, Chambers TC. Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells-in vitro and ex vivo study. J Biochem Mol Toxicol. 2020 Jun; 34(6):e22487.
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Utuama O, Mukhtar F, Pham YT, Dabo B, Manani P, Moser J, Michael-Asalu A, Tran CT, Le LC, Le TV, Vu KT, Park JY, Boffetta P, Zheng W, Shu XO, Luu HN. Racial/ethnic, age and sex disparities in leukemia survival among adults in the United States during 1973-2014 period. PLoS One. 2019; 14(8):e0220864.
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Mousavian Z, Nowzari-Dalini A, Rahmatallah Y, Masoudi-Nejad A. Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia. Mol Med. 2019 08 01; 25(1):36.
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Liberio N, Robinson H, Nugent M, Simpson P, Margolis DA, Malarkannan S, Keever-Taylor C, Thakar MS. Single-center experience suggests donor lymphocyte infusion may promote long-term survival in children with high-risk acute lymphoblastic leukemia. Pediatr Blood Cancer. 2019 11; 66(11):e27950.
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Sharkey CM, Clawson AH, Mullins LL, Brinkman TM, Pui CH, Hudson MM, Krull KR. The relationship of child executive functions to parenting capacities in childhood acute lymphoblastic leukemia survivors. Pediatr Blood Cancer. 2019 08; 66(8):e27761.
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El Chaer F, Holtzman NG, Sausville EA, Law JY, Lee ST, Duong VH, Baer MR, Koka R, Singh ZN, Hardy NM, Emadi A. Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib. Acta Haematol. 2019; 141(2):107-110.
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Knez V, Liu X, Schowinsky J, Pan Z, Wang D, Lorsbach R, Lu C, Luedke C, Haag M, Carstens B, Swisshelm K, Yang LH, Jug R, Wang E, Liang X. Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study. Leuk Lymphoma. 2019 04; 60(4):1006-1013.
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Delgado M, Chambers TC. Microtubules play an essential role in the survival of primary acute lymphoblastic leukemia cells advancing through G1 phase. Cell Cycle. 2018; 17(14):1784-1796.
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Urbaniak A, Delgado M, Antoszczak M, Huczynski A, Chambers TC. Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro. Biomed Pharmacother. 2018 Mar; 99:384-390.
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Alexander TC, Simecka CM, Kiffer F, Groves T, Anderson J, Carr H, Wang J, Carter G, Allen AR. Changes in cognition and dendritic complexity following intrathecal methotrexate and cytarabine treatment in a juvenile murine model. Behav Brain Res. 2018 07 02; 346:21-28.
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Willis E, Samanta D, Kanfi A. A Not Uncommon Cause of Stroke Mimicker in Children. Pediatr Neurol. 2018 03; 80:92-93.
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Delgado M, Kothari A, Hittelman WN, Chambers TC. Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation. J Vis Exp. 2017 11 10; (129).
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Van Der Plas E, Erdman L, Nieman BJ, Weksberg R, Butcher DT, O'connor DL, Aufreiter S, Hitzler J, Guger SL, Schachar RJ, Ito S, Spiegler BJ. Characterizing neurocognitive late effects in childhood leukemia survivors using a combination of neuropsychological and cognitive neuroscience measures. Child Neuropsychol. 2018 11; 24(8):999-1014.
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Kothari A, Caradine KD, Rico Crescencio JC, Sasapu A, Veeraputhiran MK, Jethava Y, Burgess MJ. Cytomegalovirus appendicitis after hematopoietic stem cell transplantation. Transpl Infect Dis. 2017 Oct; 19(5).
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Urbaniak A, Delgado M, Kacprzak K, Chambers TC. Activity of resveratrol triesters against primary acute lymphoblastic leukemia cells. Bioorg Med Chem Lett. 2017 06 15; 27(12):2766-2770.
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Tolbert JA, Bai S, Abdel-Rahman SM, August KJ, Weir SJ, Kearns GL, Neville KA. Pharmacokinetics of two 6-mercaptopurine liquid formulations in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 Aug; 64(8).
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van der Plas E, Schachar RJ, Hitzler J, Crosbie J, Guger SL, Spiegler BJ, Ito S, Nieman BJ. Brain structure, working memory and response inhibition in childhood leukemia survivors. Brain Behav. 2017 02; 7(2):e00621.
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Mousavian Z, Nowzari-Dalini A, Stam RW, Rahmatallah Y, Masoudi-Nejad A. Network-based expression analysis reveals key genes related to glucocorticoid resistance in infant acute lymphoblastic leukemia. Cell Oncol (Dordr). 2017 Feb; 40(1):33-45.
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Bechtel A, Joyce M, Dudek CJ, Sarandria JJ, Shah C, Saad AG. Multiple unusual lung etiologies in a child with acute lymphocytic leukemia. Pediatr Blood Cancer. 2017 03; 64(3).
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Kothari A, Hittelman WN, Chambers TC. Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells. Cancer Res. 2016 06 15; 76(12):3553-61.
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Wilken R, Fung MA, Shi VY, Cheng MY, Patel F, Sultani H, Maverakis E. Cyclosporine-induced sebaceous hyperplasia in a hematopoetic stem cell transplant patient: delayed onset of a common adverse event. Dermatol Online J. 2016 Jan 15; 22(1).
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