 Th2 Cells
"Th2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.
| Descriptor ID |
D018418
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| MeSH Number(s) |
A11.118.637.555.567.550.500.400.905 A11.118.637.555.567.569.200.400.905 A11.118.637.555.567.569.500.400.905 A15.145.229.637.555.567.550.500.400.750 A15.145.229.637.555.567.569.200.400.750 A15.145.229.637.555.567.569.500.400.750 A15.382.490.555.567.550.500.400.905 A15.382.490.555.567.569.200.400.905 A15.382.490.555.567.569.500.400.905
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| Concept/Terms |
Th2 Cells- Th2 Cells
- Cell, Th2
- Cells, Th2
- Th2 Cell
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Below are MeSH descriptors whose meaning is more general than "Th2 Cells".
- Anatomy [A]
- Cells [A11]
- Blood Cells [A11.118]
- Leukocytes [A11.118.637]
- Leukocytes, Mononuclear [A11.118.637.555]
- Lymphocytes [A11.118.637.555.567]
- Lymphocyte Subsets [A11.118.637.555.567.550]
- T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.550.500.400]
- Th2 Cells [A11.118.637.555.567.550.500.400.905]
- T-Lymphocytes [A11.118.637.555.567.569]
- CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.200.400]
- Th2 Cells [A11.118.637.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A11.118.637.555.567.569.500.400]
- Th2 Cells [A11.118.637.555.567.569.500.400.905]
- Hemic and Immune Systems [A15]
- Blood [A15.145]
- Blood Cells [A15.145.229]
- Leukocytes [A15.145.229.637]
- Leukocytes, Mononuclear [A15.145.229.637.555]
- Lymphocytes [A15.145.229.637.555.567]
- Lymphocyte Subsets [A15.145.229.637.555.567.550]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.550.500.400]
- Th2 Cells [A15.145.229.637.555.567.550.500.400.750]
- T-Lymphocytes [A15.145.229.637.555.567.569]
- CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.200.400]
- Th2 Cells [A15.145.229.637.555.567.569.200.400.750]
- T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.145.229.637.555.567.569.500.400]
- Th2 Cells [A15.145.229.637.555.567.569.500.400.750]
- Immune System [A15.382]
- Leukocytes [A15.382.490]
- Leukocytes, Mononuclear [A15.382.490.555]
- Lymphocytes [A15.382.490.555.567]
- Lymphocyte Subsets [A15.382.490.555.567.550]
- T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.550.500.400]
- Th2 Cells [A15.382.490.555.567.550.500.400.905]
- T-Lymphocytes [A15.382.490.555.567.569]
- CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.200.400]
- Th2 Cells [A15.382.490.555.567.569.200.400.905]
- T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
- T-Lymphocytes, Helper-Inducer [A15.382.490.555.567.569.500.400]
- Th2 Cells [A15.382.490.555.567.569.500.400.905]
Below are MeSH descriptors whose meaning is more specific than "Th2 Cells".
This graph shows the total number of publications written about "Th2 Cells" by people in UAMS Profiles by year, and whether "Th2 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 | | 2017 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Th2 Cells" by people in Profiles over the past ten years.
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Lozano-Ojalvo D, Tyler SR, Aranda CJ, Wang J, Sicherer S, Sampson HA, Wood RA, Burks AW, Jones SM, Leung DYM, de Lafaille MC, Berin MC. Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans. Allergy. 2023 03; 78(3):697-713.
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Wongvibulsin S, Sutaria N, Kannan S, Alphonse MP, Belzberg M, Williams KA, Brown ID, Choi J, Roh YS, Pritchard T, Khanna R, Eseonu AC, Jedrych J, Dillen C, Kwatra MM, Chien AL, Archer N, Garza LA, Dong X, Kang S, Kwatra SG. Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation. Sci Rep. 2021 05 27; 11(1):11175.
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Ludwig CM, Krase JM, Shi VY. T Helper 2 Inhibitors in Allergic Contact Dermatitis. Dermatitis. 2021 Jan-Feb 01; 32(1):15-18.
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Rowe RK, Pyle DM, Farrar JD, Gill MA. IgE-mediated regulation of IL-10 and type I IFN enhances rhinovirus-induced Th2 differentiation by primary human monocytes. Eur J Immunol. 2020 10; 50(10):1550-1559.
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Iqbal S, Lockett GA, Holloway JW, Arshad SH, Zhang H, Kaushal A, Tetali SR, Mukherjee N, Karmaus WJJ. Changes in DNA Methylation from Age 18 to Pregnancy in Type 1, 2, and 17 T Helper and Regulatory T-Cells Pathway Genes. Int J Mol Sci. 2018 Feb 06; 19(2).
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Chiang D, Chen X, Jones SM, Wood RA, Sicherer SH, Burks AW, Leung DYM, Agashe C, Grishin A, Dawson P, Davidson WF, Newman L, Sebra R, Merad M, Sampson HA, Losic B, Berin MC. Single-cell profiling of peanut-responsive T cells in patients with peanut allergy reveals heterogeneous effector TH2 subsets. J Allergy Clin Immunol. 2018 06; 141(6):2107-2120.
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Kannan AK, Mohinta S, Huang W, Huang L, Koylass N, Appleton JA, August A. T-Bet independent development of IFN? secreting natural T helper 1 cell population in the absence of Itk. Sci Rep. 2017 04 13; 7:45935.
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Karta MR, Rosenthal PS, Beppu A, Vuong CY, Miller M, Das S, Kurten RC, Doherty TA, Broide DH. ?2 integrins rather than ?1 integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung. J Allergy Clin Immunol. 2018 01; 141(1):329-338.e12.
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Rowe RK, Pyle DM, Tomlinson AR, Lv T, Hu Z, Gill MA. IgE cross-linking impairs monocyte antiviral responses and inhibits influenza-driven TH1 differentiation. J Allergy Clin Immunol. 2017 07; 140(1):294-298.e8.
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Kennedy JL, Steinke JW, Liu L, Negri J, Borish L, Payne SC. Failure of itraconazole to prevent T-helper type 2 cell immune deviation: Implications for chronic rhinosinusitis. Am J Rhinol Allergy. 2016 Nov 01; 30(6):379-384.
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