Helix-Turn-Helix Motifs
"Helix-Turn-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)
| Descriptor ID |
D019077
|
| MeSH Number(s) |
G02.111.570.790.709.600.040.360.360
|
| Concept/Terms |
Helix-Turn-Helix Motifs- Helix-Turn-Helix Motifs
- Helix Turn Helix Motifs
- Helix-Turn-Helix Motif
- Motif, Helix-Turn-Helix
- HTH Motifs
- HTH Motif
- Motif, HTH
- Motifs, HTH
- Motifs, Helix-Turn-Helix
- Motifs, Helix Turn Helix
|
Below are MeSH descriptors whose meaning is more general than "Helix-Turn-Helix Motifs".
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Below are the most recent publications written about "Helix-Turn-Helix Motifs" by people in Profiles over the past ten years.