 Thapsigargin
"Thapsigargin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM.
| Descriptor ID |
D019284
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| MeSH Number(s) |
D02.455.426.392.368.284.500.888 D02.455.849.765.793.888
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thapsigargin".
Below are MeSH descriptors whose meaning is more specific than "Thapsigargin".
This graph shows the total number of publications written about "Thapsigargin" by people in UAMS Profiles by year, and whether "Thapsigargin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2014 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thapsigargin" by people in Profiles over the past ten years.
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Al-Beltagi S, Goulding LV, Chang DKE, Mellits KH, Hayes CJ, Gershkovich P, Coleman CM, Chang KC. Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin. Virulence. 2021 12; 12(1):2946-2956.
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Smith HL, Freeman OJ, Butcher AJ, Holmqvist S, Humoud I, Sch?tzl T, Hughes DT, Verity NC, Swinden DP, Hayes J, de Weerd L, Rowitch DH, Franklin RJM, Mallucci GR. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020 03 04; 105(5):855-866.e5.
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