 Pregnenolone Carbonitrile
"Pregnenolone Carbonitrile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.
| Descriptor ID |
D011285
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| MeSH Number(s) |
D02.626.745 D04.808.745.745.725.703
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| Concept/Terms |
Pregnenolone Carbonitrile- Pregnenolone Carbonitrile
- Carbonitrile, Pregnenolone
- Pregnenolone 16 alpha-Carbonitrile
- 16 alpha-Carbonitrile, Pregnenolone
- Pregnenolone 16 alpha Carbonitrile
- PCN
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Below are MeSH descriptors whose meaning is more general than "Pregnenolone Carbonitrile".
Below are MeSH descriptors whose meaning is more specific than "Pregnenolone Carbonitrile".
This graph shows the total number of publications written about "Pregnenolone Carbonitrile" by people in UAMS Profiles by year, and whether "Pregnenolone Carbonitrile" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pregnenolone Carbonitrile" by people in Profiles over the past ten years.
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Hirashima R, Michimae H, Takemoto H, Sasaki A, Kobayashi Y, Itoh T, Tukey RH, Fujiwara R. Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity. Mol Pharmacol. 2016 09; 90(3):265-74.
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Kutsuno Y, Hirashima R, Sakamoto M, Ushikubo H, Michimae H, Itoh T, Tukey RH, Fujiwara R. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain. Drug Metab Dispos. 2015 Jul; 43(7):1071-6.
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