 Ventricular Dysfunction, Left
"Ventricular Dysfunction, Left" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Descriptor ID |
D018487
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| MeSH Number(s) |
C14.280.945.900
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| Concept/Terms |
Ventricular Dysfunction, Left- Ventricular Dysfunction, Left
- Left Ventricular Dysfunction
- Dysfunction, Left Ventricular
- Dysfunctions, Left Ventricular
- Left Ventricular Dysfunctions
- Ventricular Dysfunctions, Left
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Below are MeSH descriptors whose meaning is more general than "Ventricular Dysfunction, Left".
Below are MeSH descriptors whose meaning is more specific than "Ventricular Dysfunction, Left".
This graph shows the total number of publications written about "Ventricular Dysfunction, Left" by people in UAMS Profiles by year, and whether "Ventricular Dysfunction, Left" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2025 | 1 | 1 | 2 | | 2024 | 4 | 1 | 5 | | 2023 | 4 | 0 | 4 | | 2022 | 2 | 0 | 2 | | 2021 | 5 | 0 | 5 | | 2020 | 6 | 0 | 6 | | 2019 | 3 | 1 | 4 | | 2018 | 1 | 1 | 2 | | 2017 | 2 | 0 | 2 | | 2016 | 6 | 1 | 7 | | 2015 | 4 | 1 | 5 | | 2014 | 1 | 2 | 3 | | 2013 | 1 | 1 | 2 | | 2012 | 2 | 2 | 4 | | 2011 | 1 | 0 | 1 | | 2010 | 4 | 0 | 4 | | 2009 | 1 | 0 | 1 | | 2008 | 2 | 2 | 4 | | 2007 | 2 | 0 | 2 | | 2006 | 2 | 1 | 3 | | 2005 | 2 | 0 | 2 | | 2004 | 1 | 1 | 2 | | 2003 | 1 | 3 | 4 | | 1999 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ventricular Dysfunction, Left" by people in Profiles over the past ten years.
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Truong DT, Trachtenberg FL, Hu C, Pearson GD, Friedman K, Sabati AA, Dionne A, Oster ME, Anderson BR, Block J, Bradford TT, Campbell MJ, D'Addese L, Dummer KB, Elias MD, Forsha D, Garuba OD, Hasbani K, Hayes K, Hebson C, Jone PN, Krishnan A, Lang S, McCrindle BW, McHugh KE, Mitchell EC, Morrison T, Muniz JC, Payne RM, Portman MA, Russell MW, Sanil Y, Shakti D, Sharma K, Shea JR, Sykes M, Shekerdemian LS, Szmuszkovicz J, Thacker D, Newburger JW. Six-Month Outcomes in the Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children Study. JAMA Pediatr. 2025 Mar 01; 179(3):293-301.
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Tan RB, Pierce KA, Nielsen J, Sanatani S, Fridman MD, Stephenson EA, Rangu S, Escudero C, Mah D, Hill A, Kane AM, Chaouki AS, Ochoa Nunez L, Kwok SY, Tsao S, Kallas D, Asaki SY, Behere S, Dubin A, Ratnasamy C, Robinson JA, Janson CM, Cecchin F, Shah MJ. Dual- vs Single-Chamber Ventricular Pacing in Isolated Congenital Complete Atrioventricular Block in Infancy. JACC Clin Electrophysiol. 2025 May; 11(5):987-998.
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Al'Aref SJ, Gautam N, Mansour M, Alqaisi O, Tarun T, Devabhaktuni S, Atreya A, Abete R, Aquaro GD, Baggiano A, Barison A, Bogaert J, Camastra G, Carigi S, Carrabba N, Casavecchia G, Censi S, Cicala G, De Cecco CN, De Lazzari M, Di Giovine G, Calo L, Dobrovie M, Focardi M, Fusini L, Gaibazzi N, Gismondi A, Gravina M, Guglielmo M, Lanzillo C, Lombardi M, Lorenzoni V, Lozano-Torres J, Margonato D, Martini C, Marzo F, Masci PG, Masi A, Moro C, Muscogiuri G, Mushtaq S, Nese A, Palumbo A, Pavon AG, Pedrotti P, Marra MP, Pradella S, Presicci C, Rabbat MG, Raineri C, Rodriguez-Palomares JF, Sbarbati S, Schoepf UJ, Squeri A, Sverzellati N, Symons R, Tat E, Timpani M, Todiere G, Valentini A, Varga-Szemes A, Volpe A, Guaricci AI, Schwitter J, Pontone G. Clinical parameters of death and heart failure hospitalization in biventricular systolic dysfunction assessed via cardiac magnetic resonance. Int J Cardiol. 2025 Jan 15; 419:132709.
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Shah R, Tokodi M, Jamthikar A, Bhatti S, Akhabue E, Casaclang-Verzosa G, Yanamala N, Sengupta PP. A deep patient-similarity learning framework for the assessment of diastolic dysfunction in elderly patients. Eur Heart J Cardiovasc Imaging. 2024 Jun 28; 25(7):937-946.
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Faraji E, Bolin EH, Collins Ii RT, Greiten L, Daily JA. Author Response to Letter to the Editor Re: "Left Ventricular Dysfunction Following Repair of Ventricular Septal Defects in Infants". Pediatr Cardiol. 2024 Jun; 45(5):1161-1162.
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Mosgrove MJ, Sachdeva R, Stratton KL, Armenian SH, Bhat A, Leger KJ, Yang C, Leisenring WM, Meacham LR, Sadak KT, Narasimhan SL, Nathan PC, Chow EJ, Border WL. Utility of apical four-chamber longitudinal strain in the assessment of childhood cancer survivors: A multicenter study. Echocardiography. 2024 Feb; 41(2):e15766.
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Faraji E, Bolin EH, Bond EG, Thomas Collins R, Greiten L, Daily JA. Left Ventricular Dysfunction Following Repair of Ventricular Septal Defects in Infants. Pediatr Cardiol. 2025 Feb; 46(2):296-304.
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Kamsheh AM, Meyers KE, Palermo RA, Wu L, Burstein DS, Edelson JB, Lin KY, Maeda K, Rossano JW, Wittlieb-Weber CA, O'Connor MJ. Hypertension: An Important But Reversible Cause of Systolic Dysfunction in a Cohort of Pediatric Patients. Pediatr Cardiol. 2024 Feb; 45(2):331-339.
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Hoffmann RM, Neal JT, Arichai P, Gravel CA, Neuman MI, Monuteaux MC, Levy JA, Miller AF. Test Characteristics of Cardiac Point-of-Care Ultrasound in Children With Preexisting Cardiac Conditions. Pediatr Emerg Care. 2024 Apr 01; 40(4):307-310.
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Lopez-Candales A, Asif T, Sawalha K, Norgard NB. Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction. Cardiovasc Ther. 2023; 2023:1552826.
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Abdelrahim E, Birchak J, Khan A, Maskoun W. Iatrogenic cardiomyopathy in patients with manifest right supero-paraseptal accessory pathways. Pacing Clin Electrophysiol. 2023 11; 46(11):1370-1374.
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Connor BS, Algaze CA, Narkeviciute A, Anguiano B, Pariani M, Zarate YA, Collins RT. Prevalence and Outcomes of Primary Left Ventricular Dysfunction in Marfan Syndrome. Am J Cardiol. 2022 07 15; 175:119-126.
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He M, Leone DM, Frye R, Ferdman DJ, Shabanova V, Kosiv KA, Sugeng L, Faherty E, Karnik R. Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C). Pediatr Cardiol. 2022 Apr; 43(4):844-854.
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Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 07 01; 385(1):23-34.
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Hofrichter P, Hagendorff A, Laufs U, Fikenzer S, Hepp P, Marshall RP, Tayal B, St?be S. Analysis of left ventricular rotational deformation by 2D speckle tracking echocardiography: a feasibility study in athletes. Int J Cardiovasc Imaging. 2021 Aug; 37(8):2369-2386.
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Yoneyama F, Imamura M, Kalra R. Intrinsic Coronary Stenosis With Ventricular Dysfunction in Tetralogy of Fallot. Ann Thorac Surg. 2021 11; 112(5):e333-e335.
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Ginsburg S, Conlon T, Himebauch A, Glau C, Weiss S, Weber MD, O'Connor MJ, Nishisaki A. Left Ventricular Diastolic Dysfunction in Pediatric Sepsis: Outcomes in a Single-Center Retrospective Cohort Study. Pediatr Crit Care Med. 2021 03 01; 22(3):275-285.
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Sachdeva R, Stratton KL, Cox DE, Armenian SH, Bhat A, Border WL, Leger KJ, Leisenring WM, Meacham LR, Sadak KT, Narasimhan S, Chow EJ, Nathan PC. Challenges associated with retrospective analysis of left ventricular function using clinical echocardiograms from a multicenter research study. Echocardiography. 2021 02; 38(2):296-303.
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Siddiqui S, Alsaied T, Henson SE, Gandhi J, Patel P, Khoury P, Villa C, Ryan TD, Wittekind SG, Lang SM, Taylor MD. Left Ventricular Magnetic Resonance Imaging Strain Predicts the Onset of Duchenne Muscular Dystrophy-Associated Cardiomyopathy. Circ Cardiovasc Imaging. 2020 11; 13(11):e011526.
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Alsaied T, Moore RA, Lang SM, Truong V, Lubert AM, Veldtman GR, Averin K, Dillman JR, Trout AT, Mazur W, Taylor MD, He Q, Morales DL, Redington AN, Goldstein BH. Myocardial fibrosis, diastolic dysfunction and elevated liver stiffness in the Fontan circulation. Open Heart. 2020 10; 7(2).
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Gaitonde M, Ziebell D, Kelleman MS, Cox DE, Lipinski J, Border WL, Sachdeva R. COVID-19-Related Multisystem Inflammatory Syndrome in Children Affects Left Ventricular Function and Global Strain Compared with Kawasaki Disease. J Am Soc Echocardiogr. 2020 10; 33(10):1285-1287.
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Kandels J, Tayal B, Hagendorff A, Lavall D, Laufs U, Sogaard P, Andersen NH, St?be S. "Pure" severe aortic stenosis without concomitant valvular heart diseases: echocardiographic and pathophysiological features. Int J Cardiovasc Imaging. 2020 Oct; 36(10):1917-1929.
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McCulloch MA, Lal AK, Knecht K, Butts RJ, Villa CR, Johnson JN, Conway J, Bock MJ, Schumacher KR, Law SP, Friedland-Little JM, Deshpande SR, West SC, Lytrivi ID, Gambetta KE, Wittlieb-Weber CA. Implantable Cardioverter Defibrillator Use in Males with Duchenne Muscular Dystrophy and Severe Left Ventricular Dysfunction. Pediatr Cardiol. 2020 Jun; 41(5):925-931.
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James KA, Gralla J, Ridall LA, Do TN, Czaja AS, Mourani PM, Ciafaloni E, Cunniff C, Donnelly J, Oleszek J, Pandya S, Price E, Yang ML, Auerbach SR. Left ventricular dysfunction in Duchenne muscular dystrophy. Cardiol Young. 2020 Feb; 30(2):171-176.
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Malik AO, Omer M, Pflederer MC, Almomani A, Gosch KL, Jones PG, Peri-Okonny PA, Al Badarin F, Brandt HA, Arnold SV, Main ML, Cohen DJ, Spertus JA, Chhatriwalla AK. Association Between Diastolic Dysfunction and Health Status Outcomes in Patients?Undergoing Transcatheter Aortic?Valve?Replacement. JACC Cardiovasc Interv. 2019 12 23; 12(24):2476-2484.
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Sch?fer M, Browne LP, Jaggers J, Barker AJ, Morgan GJ, Ivy DD, Mitchell MB. Abnormal left ventricular flow organization following repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 2020 Oct; 160(4):1008-1015.
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Kamran S, Akhtar N, George P, Singh R, Imam Y, Salam A, Babu B, Burke P, Own A, Vattoth S, Perkins J, Parray A, Qadri S, Hamid T. Embolic Pattern of Stroke Associated with Cardiac Wall Motion Abnormalities; Narrowing the Embolic Stroke of Undetermined Source Category. J Stroke Cerebrovasc Dis. 2020 Feb; 29(2):104509.
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Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, Spearman AD, Sonin DL, Bordas M, Kumar SN, Pan AY, Simpson PM, Strande JL, Bishop E, Zou MH, Ramchandran R. Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart. J Am Heart Assoc. 2019 11 19; 8(22):e012792.
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Shrout T, Sexton T, Vsevolozhskaya O, Guglin M, Shafii A, Smyth S. Early signatures of bleeding and mortality in patients on left ventricular assist device support: novel methods for personalized risk-stratification. Biomarkers. 2019 Jul; 24(5):448-456.
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Abdul Ghaffar Y, Maskoun W, Mustafa NG, Feigenbaum H, Sawada SG. Low dose wall motion score predicts the short and long-term benefit of surgical revascularization in patients with ischemic left ventricular dysfunction. Int J Cardiovasc Imaging. 2019 Sep; 35(9):1651-1659.
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Siraj A, Pattanshetty DJ, Agarwal SK, Uretsky BF. Retrograde recanalization of a nonchronic total occlusion lesion. Catheter Cardiovasc Interv. 2018 12 01; 92(7):1293-1296.
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Nawaytou HM, Montero AE, Yubbu P, Calder?n-Anyosa RJC, Sato T, O'Connor MJ, Miller KD, Ursell PC, Hoffman JIE, Banerjee A. A Preliminary Study of Left Ventricular Rotational Mechanics in Children with Noncompaction Cardiomyopathy: Do They Influence Ventricular Function? J Am Soc Echocardiogr. 2018 08; 31(8):951-961.
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Marmagkiolis K, Cilingiroglu M, Grines CL. Transradial Coronary Angiogram in a Sitting Position. J Invasive Cardiol. 2017 Aug; 29(8):E88-E89.
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Wen JJ, Porter C, Garg NJ. Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease. Antioxid Redox Signal. 2017 Sep 20; 27(9):550-566.
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Randolph TC, Broderick S, Shaw LK, Chiswell K, Mentz RJ, Kutyifa V, Velazquez EJ, Gilliam FR, Thomas KL. Race and Sex Differences in QRS Interval and Associated Outcome Among Patients with Left Ventricular Systolic Dysfunction. J Am Heart Assoc. 2017 Mar 20; 6(3).
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Williams FZ, Sachdeva R, Travers CD, Walson KH, Hebbar KB. Characterization of Myocardial Dysfunction in Fluid- and Catecholamine-Refractory Pediatric Septic Shock and Its Clinical Significance. J Intensive Care Med. 2019 Jan; 34(1):17-25.
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Tayal B, Sogaard P, Delgado-Montero A, Goda A, Saba S, Risum N, Gorcsan J. Interaction of Left Ventricular Remodeling and Regional Dyssynchrony on Long-Term Prognosis after Cardiac Resynchronization Therapy. J Am Soc Echocardiogr. 2017 Mar; 30(3):244-250.
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Nawaytou HM, Yubbu P, Montero AE, Nandi D, O'Connor MJ, Shaddy RE, Banerjee A. Left Ventricular Rotational Mechanics in Children After Heart Transplantation. Circ Cardiovasc Imaging. 2016 09; 9(9).
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Ferguson ME, Sachdeva R, Gillespie SE, Morrow G, Border W. Tissue Doppler imaging during exercise stress echocardiography demonstrates a mechanism for impaired exercise performance in children with hypertrophic cardiomyopathy. Echocardiography. 2016 Nov; 33(11):1718-1725.
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Fadol AP, Banchs J, Hassan SA, Yeh ET, Fellman B. Withdrawal of Heart Failure Medications in Cancer Survivors With Chemotherapy-Induced Left Ventricular Dysfunction: A Pilot Study. J Card Fail. 2016 Jun; 22(6):481-2.
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Niss O, Quinn CT, Lane A, Daily J, Khoury PR, Bakeer N, Kimball TR, Towbin JA, Malik P, Taylor MD. Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease. JACC Cardiovasc Imaging. 2016 Mar; 9(3):243-52.
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Olson M, Hebson C, Ehrlich A, New T, Sachdeva R. Tissue Doppler Imaging-derived Diastolic Function Assessment in Children With Sickle Cell Disease and Its Relation With Ferritin. J Pediatr Hematol Oncol. 2016 Jan; 38(1):17-21.
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Gorcsan J, Tayal B. Newer Echocardiographic Techniques in Cardiac Resynchronization Therapy. Card Electrophysiol Clin. 2015 Dec; 7(4):609-18.
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Zhang W, Deng J, Sunkara M, Morris AJ, Wang C, St Clair D, Vore M. Loss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice. J Pharmacol Exp Ther. 2015 Nov; 355(2):280-7.
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Weltman NY, Pol CJ, Zhang Y, Wang Y, Koder A, Raza S, Zucchi R, Saba A, Colligiani D, Gerdes AM. Long-term physiological T3 supplementation in hypertensive heart disease in rats. Am J Physiol Heart Circ Physiol. 2015 Sep 15; 309(6):H1059-65.
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