 Neurofibroma
"Neurofibroma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Descriptor ID |
D009455
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| MeSH Number(s) |
C04.557.580.600.580 C10.551.775.500.750 C10.668.829.725.500.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurofibroma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma".
This graph shows the total number of publications written about "Neurofibroma" by people in UAMS Profiles by year, and whether "Neurofibroma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 2 | 3 | | 2023 | 7 | 0 | 7 | | 2014 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 1990 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurofibroma" by people in Profiles over the past ten years.
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Lin MJ, Yao H, Vera K, Patel E, Johnson M, Caroline P, Ramos J, Mehta J, Hu X, Blakeley JO, Romo CG, Sarin KY. Cutaneous Neurofibromas and Quality of Life in Adults With Neurofibromatosis Type 1. JAMA Dermatol. 2024 Oct 01; 160(10):1091-1098.
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Lau JCL, Fleming J, Good M, Lim A, Saunderson RB, Phan TA, Schlub T, Siow SF, Lacson N, Romo C, Blakely J, Bergqvist C, Berman YD. Comparing 3D imaging devices for the measurement of cutaneous neurofibromas in patients with Neurofibromatosis Type 1. Skin Res Technol. 2024 Sep; 30(9):e70020.
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Romo CG, Sarin KY, Blakeley JO. Toward risk stratification and personalized therapy for neurofibromas in?neurofibromatosis type 1. Br J Dermatol. 2024 01 23; 190(2):145-146.
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Blakeley JO, Le LQ, Lee SY, Ly I, Rhodes SD, Romo CG, Sarin KY, Staedtke V, Steensma MR, Wolkenstein P. A Call for Discovery and Therapeutic Development for Cutaneous Neurofibromas. J Invest Dermatol. 2023 08; 143(8):1351-1357.
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Li Y, Blakeley JO, Ly I, Berman Y, Lau J, Wolkenstein P, Bergqvist C, Jia W, Milner TE, Katta N, Durkin AJ, Kennedy GT, Rowland R, Romo CG, Fleming J, Kelly KM. Current and Emerging Imaging Techniques for Neurofibromatosis Type 1-Associated Cutaneous Neurofibromas. J Invest Dermatol. 2023 08; 143(8):1397-1405.
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Staedtke V, Topilko P, Le LQ, Grimes K, Largaespada DA, Cagan RL, Steensma MR, Stemmer-Rachamimov A, Blakeley JO, Rhodes SD, Ly I, Romo CG, Lee SY, Serra E. Existing and Developing Preclinical Models for Neurofibromatosis Type 1-Related Cutaneous Neurofibromas. J Invest Dermatol. 2023 08; 143(8):1378-1387.
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Jiang C, McKay RM, Lee SY, Romo CG, Blakeley JO, Haniffa M, Serra E, Steensma MR, Largaespada D, Le LQ. Cutaneous Neurofibroma Heterogeneity: Factors that Influence Tumor Burden in Neurofibromatosis Type 1. J Invest Dermatol. 2023 08; 143(8):1369-1377.
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Ly I, Romo CG, Gottesman S, Kelly KM, Kornacki D, York Z, Lee SY, Rhodes SD, Staedtke V, Steensma MR, Blakeley JO, Wolkenstein P. Target Product Profile for Cutaneous Neurofibromas: Clinical Trials to Prevent, Arrest, or Regress Cutaneous Neurofibromas. J Invest Dermatol. 2023 08; 143(8):1388-1396.
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Rhodes SD, McCormick F, Cagan RL, Bakker A, Staedtke V, Ly I, Steensma MR, Lee SY, Romo CG, Blakeley JO, Sarin KY. RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in Cutaneous Neurofibroma Pathogenesis, Emerging Biological Insights. J Invest Dermatol. 2023 08; 143(8):1358-1368.
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Gelikman DG, Bhupalam V, Birusingh RJ, Ellsworth P, Seth A. Solitary Intrascrotal Plexiform Neurofibroma in a 10-Year-Old Male. Urology. 2023 08; 178:143-146.
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