Multiple Endocrine Neoplasia Type 2b

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Multiple Endocrine Neoplasia Type 2b

"Multiple Endocrine Neoplasia Type 2b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease.

Descriptor ID	D018814
MeSH Number(s)	C04.588.322.400.510 C04.651.600.510 C04.700.630.510 C16.320.700.630.510 C19.344.400.510
Concept/Terms	Multiple Endocrine Neoplasia Type 2b Multiple Endocrine Neoplasia Type 2b Multiple Endocrine Neoplasia, Type 2b Multiple Endocrine Neoplasms Type 2b Neoplasia, Multiple Endocrine Type 2b Neoplasms, Multiple Endocrine Type 2b Neuromata, Mucosal, With Endocrine Tumors Wagenmann-Froboese Syndrome Syndrome, Wagenmann-Froboese Wagenmann Froboese Syndrome Multiple Endocrine Neoplasia, Type IIb MEA 2b MEA IIb MEN 2b MEN 3 MEN IIb MEN III MEN2b Mucosal Neuroma Syndrome Mucosal Neuroma Syndromes Neuroma Syndrome, Mucosal

Below are MeSH descriptors whose meaning is more general than "Multiple Endocrine Neoplasia Type 2b".

Diseases [C]
Neoplasms [C04]
Neoplasms by Site [C04.588]
Endocrine Gland Neoplasms [C04.588.322]
Multiple Endocrine Neoplasia [C04.588.322.400]
Multiple Endocrine Neoplasia Type 2b [C04.588.322.400.510]
Neoplasms, Multiple Primary [C04.651]
Multiple Endocrine Neoplasia [C04.651.600]
Multiple Endocrine Neoplasia Type 2b [C04.651.600.510]
Neoplastic Syndromes, Hereditary [C04.700]
Multiple Endocrine Neoplasia [C04.700.630]
Multiple Endocrine Neoplasia Type 2b [C04.700.630.510]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Neoplastic Syndromes, Hereditary [C16.320.700]
Multiple Endocrine Neoplasia [C16.320.700.630]
Multiple Endocrine Neoplasia Type 2b [C16.320.700.630.510]
Endocrine System Diseases [C19]
Endocrine Gland Neoplasms [C19.344]
Multiple Endocrine Neoplasia [C19.344.400]
Multiple Endocrine Neoplasia Type 2b [C19.344.400.510]

Below are MeSH descriptors whose meaning is related to "Multiple Endocrine Neoplasia Type 2b".

Below are MeSH descriptors whose meaning is more specific than "Multiple Endocrine Neoplasia Type 2b".

publications

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