 Hyperalgesia
"Hyperalgesia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
| Descriptor ID |
D006930
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| MeSH Number(s) |
C10.597.751.791.400 C23.888.592.763.770.400
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| Concept/Terms |
Hyperalgesia- Hyperalgesia
- Hyperalgesias
- Hyperalgesic Sensations
Mechanical Allodynia- Mechanical Allodynia
- Allodynias, Mechanical
- Hyperalgesia, Mechanical
- Hyperalgesias, Mechanical
- Mechanical Hyperalgesia
- Allodynia, Mechanical
Tactile Allodynia- Tactile Allodynia
- Allodynias, Tactile
- Hyperalgesia, Tactile
- Hyperalgesias, Tactile
- Allodynia, Tactile
Hyperalgesia, Thermal- Hyperalgesia, Thermal
- Hyperalgesias, Thermal
- Thermal Hyperalgesia
- Thermal Allodynia
- Allodynia, Thermal
- Allodynias, Thermal
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Below are MeSH descriptors whose meaning is more general than "Hyperalgesia".
Below are MeSH descriptors whose meaning is more specific than "Hyperalgesia".
This graph shows the total number of publications written about "Hyperalgesia" by people in UAMS Profiles by year, and whether "Hyperalgesia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2022 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2018 | 3 | 0 | 3 | | 2017 | 2 | 1 | 3 | | 2016 | 0 | 2 | 2 | | 2015 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2013 | 2 | 0 | 2 | | 2012 | 1 | 2 | 3 | | 2011 | 1 | 2 | 3 | | 2010 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2006 | 3 | 0 | 3 | | 2004 | 3 | 0 | 3 | | 2003 | 2 | 0 | 2 | | 2002 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Hyperalgesia" by people in Profiles over the past ten years.
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Tam TH, Zhang W, Tu Y, Hicks JL, Farcas S, Kim D, Salter MW. Pain hypersensitivity is dependent on autophagy protein Beclin 1 in males but not females. Cell Rep. 2024 Jun 25; 43(6):114293.
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Ghazisaeidi S, Muley MM, Tu Y, Finn DP, Kolahdouzan M, Pitcher GM, Kim D, Sengar AS, Ramani AK, Brudno M, Salter MW. Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain. Br J Pharmacol. 2023 11; 180(21):2822-2836.
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Tsujikawa S, DeMeulenaere KE, Centeno MV, Ghazisaeidi S, Martin ME, Tapies MR, Maneshi MM, Yamashita M, Stauderman KA, Apkarian AV, Salter MW, Prakriya M. Regulation of neuropathic pain by microglial Orai1 channels. Sci Adv. 2023 01 27; 9(4):eade7002.
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Tu Y, Muley MM, Beggs S, Salter MW. Microglia-independent peripheral neuropathic pain in male and female mice. Pain. 2022 11 01; 163(11):e1129-e1144.
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Acklin S, Zhang M, Du W, Zhao X, Plotkin M, Chang J, Campisi J, Zhou D, Xia F. Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice. Sci Rep. 2020 08 25; 10(1):14170.
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Mapplebeck JCS, Lorenzo LE, Lee KY, Gauthier C, Muley MM, De Koninck Y, Prescott SA, Salter MW. Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes. Cell Rep. 2019 07 16; 28(3):590-596.e4.
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Moriarty O, Tu Y, Sengar AS, Salter MW, Beggs S, Walker SM. Priming of Adult Incision Response by Early-Life Injury: Neonatal Microglial Inhibition Has Persistent But Sexually Dimorphic Effects in Adult Rats. J Neurosci. 2019 04 17; 39(16):3081-3093.
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Mapplebeck JCS, Dalgarno R, Tu Y, Moriarty O, Beggs S, Kwok CHT, Halievski K, Assi S, Mogil JS, Trang T, Salter MW. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain. 2018 Sep; 159(9):1752-1763.
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Rosen JM, Yaggie RE, Woida PJ, Miller RJ, Schaeffer AJ, Klumpp DJ. TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain. Sci Rep. 2018 05 08; 8(1):7188.
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Yadlapalli JSK, Dogra N, Walbaum AW, Prather PL, Crooks PA, Dobretsov M. Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome? Neurosci Lett. 2018 04 23; 673:24-27.
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Crowe MS, Wilson CD, Leishman E, Prather PL, Bradshaw HB, Banks ML, Kinsey SG. The monoacylglycerol lipase inhibitor KML29 with gabapentin synergistically produces analgesia in mice. Br J Pharmacol. 2017 Dec; 174(23):4523-4539.
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Yang W, Yaggie RE, Jiang MC, Rudick CN, Done J, Heckman CJ, Rosen JM, Schaeffer AJ, Klumpp DJ. Acyloxyacyl hydrolase modulates pelvic pain severity. Am J Physiol Regul Integr Comp Physiol. 2018 03 01; 314(3):R353-R365.
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Hayes CJ, Painter JT. A comprehensive clinical review of opioid-induced allodynia: Discussion of the current evidence and clinical implications. J Opioid Manag. 2017 Mar/Apr; 13(2):95-103.
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Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, Masuda T, Kohro Y, Matsunaga N, Tsuda M, Salter MW, Inoue K, Ohdo S. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016 10 14; 7:13102.
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Kee JR, Smith RG, Barnes CL. Recognizing and Reducing the Risk of Opioid Misuse in Orthopaedic Practice. J Surg Orthop Adv. 2016 Winter; 25(4):238-243.
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Sorge RE, Mapplebeck JC, Rosen S, Beggs S, Taves S, Alexander JK, Martin LJ, Austin JS, Sotocinal SG, Chen D, Yang M, Shi XQ, Huang H, Pillon NJ, Bilan PJ, Tu Y, Klip A, Ji RR, Zhang J, Salter MW, Mogil JS. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat Neurosci. 2015 Aug; 18(8):1081-3.
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