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Complement Pathway, Mannose-Binding Lectin

"Complement Pathway, Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.


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This graph shows the total number of publications written about "Complement Pathway, Mannose-Binding Lectin" by people in UAMS Profiles by year, and whether "Complement Pathway, Mannose-Binding Lectin" was a major or minor topic of these publications.
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