Complement Pathway, Mannose-Binding Lectin

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Complement Pathway, Mannose-Binding Lectin

"Complement Pathway, Mannose-Binding Lectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.

Descriptor ID	D037582
MeSH Number(s)	G12.425.255.849
Concept/Terms	Complement Pathway, Mannose-Binding Lectin Complement Pathway, Mannose-Binding Lectin Complement Pathway, Mannose Binding Lectin Lectin-Complement Pathway Lectin Complement Pathway Lectin-Complement Pathways Pathway, Lectin-Complement Pathways, Lectin-Complement Mannan-Binding Lectin Complement Pathway Mannan Binding Lectin Complement Pathway Mannose-Binding Lectin Complement Pathway Mannose Binding Lectin Complement Pathway Mannan-Binding Lectin Pathway (Complement Activation) Lectin Pathway, Mannan-Binding (Complement Activation) Lectin Pathways, Mannan-Binding (Complement Activation) Mannan Binding Lectin Pathway (Complement Activation) Mannan-Binding Lectin Pathways (Complement Activation) Pathway, Mannan-Binding Lectin (Complement Activation) Pathways, Mannan-Binding Lectin (Complement Activation)

Below are MeSH descriptors whose meaning is more general than "Complement Pathway, Mannose-Binding Lectin".

Biological Sciences [G]
Immune System Phenomena [G12]
Immune System Processes [G12.425]
Complement Activation [G12.425.255]
Complement Pathway, Mannose-Binding Lectin [G12.425.255.849]

Below are MeSH descriptors whose meaning is related to "Complement Pathway, Mannose-Binding Lectin".

Below are MeSH descriptors whose meaning is more specific than "Complement Pathway, Mannose-Binding Lectin".

publications

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