 Optic Atrophy
"Optic Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.
| Descriptor ID |
D009896
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| MeSH Number(s) |
C10.292.700.225 C11.640.451
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Optic Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Optic Atrophy".
This graph shows the total number of publications written about "Optic Atrophy" by people in UAMS Profiles by year, and whether "Optic Atrophy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 | | 2022 | 3 | 0 | 3 | | 2019 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Optic Atrophy" by people in Profiles over the past ten years.
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Benkirane M, Bonhomme M, Morsy H, Safgren SL, Marelli C, Chaussenot A, Smedley D, Cipriani V, de Sainte-Agathe JM, Ding C, Larrieu L, Vestito L, Margot H, Lesca G, Ramond F, Castrioto A, Baux D, Verheijen J, Sansa E, Giunti P, Haetty A, Bergougnoux A, Pointaux M, Ardouin O, Van Goethem C, Vincent MC, Hadjivassiliou M, Coss?e M, Rouaud T, Bartsch O, Freeman WD, Wierenga KJ, Klee EW, Vandrovcova J, Houlden H, Debant A, Koenig M. De novo and inherited monoallelic variants in TUBA4A cause ataxia and spasticity. Brain. 2024 Nov 04; 147(11):3681-3689.
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Ong J, Mortensen P, Raviskanthan S, Pakravan M, Charoenkijkajorn C, Davila-Siliezar P, Laylani NA, Lee AG. Delayed Visual Improvement in Neuromyelitis Optica Spectrum Disorder With Severe Optic Atrophy. J Neuroophthalmol. 2024 Sep 01; 44(3):e348-e349.
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Charoenkijkajorn C, Cho J, Lee AG. Unexplained Bilateral Optic Atrophy for Decades. J Neuroophthalmol. 2022 12 01; 42(4):e609.
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Miller MJ, Lindsey JW, Pakravan M, Charoenkijkajorn C, Samant R, Milea D, Lee AG. Progressive Optic Neuropathy in Cerebellar Ataxia, Areflexia, Optic Atrophy, and Sensorineural Hearing Loss Syndrome: The Importance of Targeted Gene Testing. J Neuroophthalmol. 2024 Mar 01; 44(1):e23-e25.
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Kulek AR, Undyala VVR, Anzell AR, Raghunayakula S, MacMillan-Crow LA, Sanderson TH, Przyklenk K. Does Disruption of Optic Atrophy-1 (OPA1) Contribute to Cell Death in HL-1 Cardiomyocytes Subjected to Lethal Ischemia-Reperfusion Injury? Cells. 2022 09 30; 11(19).
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Chacko JA, Phillips PH, Ramakrishnaiah RH, Schaefer GB, Uwaydat SH. Diagnosis of Charcot-Marie-Tooth Disease in a Patient With Decreased Vision From Optic Atrophy and No Other Neurological Symptoms. J Neuroophthalmol. 2023 Dec 01; 43(4):e146-e148.
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Sharkia R, Wierenga KJ, Kessel A, Azem A, Bertini E, Carrozzo R, Torraco A, Goffrini P, Ceccatelli Berti C, McCormick ME, Plecko B, Klein A, Abela L, Hengel H, Sch?ls L, Shalev S, Khayat M, Mahajnah M, Spiegel R. Clinical, radiological, and genetic characteristics of 16 patients with ACO2 gene defects: Delineation of an emerging neurometabolic syndrome. J Inherit Metab Dis. 2019 03; 42(2):264-275.
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Chacko JG, Behbehani R, Hundley KN, Al-Fanek Y. Bortezomib-Associated Optic Atrophy in Two Patients With Multiple Myeloma. J Neuroophthalmol. 2018 12; 38(4):473-475.
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Samanta D, Gokden M. PEHO syndrome: KIF1A mutation and decreased activity of mitochondrial respiratory chain complex. J Clin Neurosci. 2019 Mar; 61:298-301.
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Peng Y, Shinde DN, Valencia CA, Mo JS, Rosenfeld J, Truitt Cho M, Chamberlin A, Li Z, Liu J, Gui B, Brockhage R, Basinger A, Alvarez-Leon B, Heydemann P, Magoulas PL, Lewis AM, Scaglia F, Gril S, Chong SC, Bower M, Monaghan KG, Willaert R, Plona MR, Dineen R, Milan F, Hoganson G, Powis Z, Helbig KL, Keller-Ramey J, Harris B, Anderson LC, Green T, Sukoff Rizzo SJ, Kaylor J, Chen J, Guan MX, Sellars E, Sparagana SP, Gibson JB, Reinholdt LG, Tang S, Huang T. Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. Hum Mol Genet. 2017 12 15; 26(24):4937-4950.
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