Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.

Descriptor ID	D005097
MeSH Number(s)	C04.557.450.565.575.610.615.325 C04.700.330 C05.116.099.708.670.615.325 C05.116.540.310.500 C16.320.700.330
Concept/Terms	Exostoses, Multiple Hereditary Exostoses, Multiple Hereditary Hereditary Exostoses, Multiple Multiple Hereditary Exostoses Diaphyseal Aclasis Aclases, Diaphyseal Aclasis, Diaphyseal Diaphyseal Aclases Exostoses, Familial Familial Exostoses Exostoses, Hereditary Multiple Multiple Exostoses, Hereditary Exostoses, Multiple Multiple Exostoses Exostoses, Multiple Cartilaginous Cartilaginous Exostoses, Multiple Exostoses, Multiple, Type I Exostosis, Familial Familial Exostosis Exostosis, Hereditary Multiple Multiple Exostosis, Hereditary Exostosis, Multiple Multiple Exostosis Exostosis, Multiple Cartilaginous Cartilaginous Exostosis, Multiple Multiple Cartilaginous Exostosis Hereditary Multiple Exostoses Hereditary Multiple Exostosis Multiple Cartilaginous Exostoses Multiple Osteochondromas Multiple Osteochondroma Osteochondroma, Multiple Osteochondromas, Multiple Chondrodysplasia, Hereditary Deforming Chondrodysplasias, Hereditary Deforming Deforming Chondrodysplasia, Hereditary Deforming Chondrodysplasias, Hereditary Hereditary Deforming Chondrodysplasia Hereditary Deforming Chondrodysplasias

Below are MeSH descriptors whose meaning is more general than "Exostoses, Multiple Hereditary".

Below are MeSH descriptors whose meaning is related to "Exostoses, Multiple Hereditary".

Below are MeSH descriptors whose meaning is more specific than "Exostoses, Multiple Hereditary".