 Kainic Acid
"Kainic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.
| Descriptor ID |
D007608
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| MeSH Number(s) |
D03.383.773.400
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| Concept/Terms |
Kainic Acid- Kainic Acid
- Acid, Kainic
- Digenic Acid
- Acid, Digenic
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Below are MeSH descriptors whose meaning is more general than "Kainic Acid".
Below are MeSH descriptors whose meaning is more specific than "Kainic Acid".
This graph shows the total number of publications written about "Kainic Acid" by people in UAMS Profiles by year, and whether "Kainic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 4 | 0 | 4 | | 2014 | 0 | 1 | 1 | | 2012 | 1 | 2 | 3 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2008 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 |
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Below are the most recent publications written about "Kainic Acid" by people in Profiles over the past ten years.
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Xu D, Wang Z, Brennan GL, Wei Y, Zheng G, Luan Q, Huang X, Sun Y, Yang J, Zhang X, Sun K, Fan X, Wang Y, Tan Z, Bowler C, Pierella Karlusich JJ, Fu FX, Gao G, Hutchins DA, Ye N. Meta-Omics Analysis Reveals Global Distribution of Toxic Pseudo-nitzschia and Enhanced Neurotoxin Production Under Climate Warming. Glob Chang Biol. 2025 Jul; 31(7):e70384.
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Kelly KJ, Mansour A, Liang C, Kim AM, Mancini LA, Bertin MJ, Jenkins BD, Hutchins DA, Fu FX. Simulated upwelling and marine heatwave events promote similar growth rates but differential domoic acid toxicity in Pseudo-nitzschia australis. Harmful Algae. 2023 08; 127:102467.
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Kang YJ, Clement EM, Park IH, Greenfield LJ, Smith BN, Lee SH. Vulnerability of cholecystokinin-expressing GABAergic interneurons in the unilateral intrahippocampal kainate mouse model of temporal lobe epilepsy. Exp Neurol. 2021 08; 342:113724.
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Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborn?k M, Smith GJ, Hutchins DA, Allen AE, Moore BS. Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom. Science. 2018 09 28; 361(6409):1356-1358.
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Zhu Z, Qu P, Fu F, Tennenbaum N, Tatters AO, Hutchins DA. Understanding the blob bloom: Warming increases toxicity and abundance of the harmful bloom diatom Pseudo-nitzschia in California coastal waters. Harmful Algae. 2017 07; 67:36-43.
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Armstrong C, Wang J, Yeun Lee S, Broderick J, Bezaire MJ, Lee SH, Soltesz I. Target-selectivity of parvalbumin-positive interneurons in layer II of medial entorhinal cortex in normal and epileptic animals. Hippocampus. 2016 06; 26(6):779-93.
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