 beta-Lactamases
"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
| Descriptor ID |
D001618
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| MeSH Number(s) |
D08.811.277.087.180
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in UAMS Profiles by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "beta-Lactamases" by people in Profiles over the past ten years.
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Lemon JK, Jankowsi-Romano C, Duong S, Juretschko S, Streva VA. Evaluation of gradient strip diffusion for susceptibility testing of aztreonam-avibactam in metallo-?-lactamase-producing Enterobacterales. J Clin Microbiol. 2024 Nov 13; 62(11):e0064924.
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Songsaeng W, Prapasarakul N, Wongsurawat T, Sirichokchatchawan W. The occurrence and genomic characteristics of the blaIMI-1 carbapenemase-producing Enterobacter cloacae complex retrieved from natural water sources in central Thailand. J Appl Microbiol. 2023 Oct 04; 134(10).
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Moon SH, Huang E. Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum ?-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35. Microbiol Spectr. 2023 06 15; 11(3):e0349622.
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Satlin MJ, Chen L, Gomez-Simmonds A, Marino J, Weston G, Bhowmick T, Seo SK, Sperber SJ, Kim AC, Eilertson B, Derti S, Jenkins SG, Levi MH, Weinstein MP, Tang YW, Hong T, Juretschko S, Hoffman KL, Walsh TJ, Westblade LF, Uhlemann AC, Kreiswirth BN. Impact of a Rapid Molecular Test for Klebsiella pneumoniae Carbapenemase and Ceftazidime-Avibactam Use on Outcomes After Bacteremia Caused by Carbapenem-Resistant Enterobacterales. Clin Infect Dis. 2022 12 19; 75(12):2066-2075.
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Moon SH, Udaondo Z, Jun SR, Huang E. Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and ?-lactamase activities. Int J Antimicrob Agents. 2022 09; 60(3):106635.
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Moon SH, Udaondo Z, Li X, Yang X, Jun SR, Huang E. Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable. J Glob Antimicrob Resist. 2021 09; 26:264-265.
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Alamarat ZI, Babic J, Tran TT, Wootton SH, Dinh AQ, Miller WR, Hanson B, Wanger A, Gary JL, Arias CA, P?rez N. Long-Term Compassionate Use of Cefiderocol To Treat Chronic Osteomyelitis Caused by Extensively Drug-Resistant Pseudomonas aeruginosa and Extended-Spectrum-?-Lactamase-Producing Klebsiella pneumoniae in a Pediatric Patient. Antimicrob Agents Chemother. 2020 03 24; 64(4).
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Ming DK, Otter JA, Ghani R, Brannigan ET, Boonyasiri A, Mookerjee S, Gilchrist M, Holmes AH, Davies F. Clinical risk stratification and antibiotic management of NDM and OXA-48 carbapenemase-producing Enterobacteriaceae bloodstream infections in the UK. J Hosp Infect. 2019 05; 102(1):95-97.
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Vella V, Moore LS, Robotham JV, Davies F, Birgand GJ, Otter JA, Brannigan E, Dyakova E, Knight GM, Mookerjee S, Holmes AH. Isolation demand from carbapenemase-producing Enterobacteriaceae screening strategies based on a West London hospital network. J Hosp Infect. 2016 Oct; 94(2):118-24.
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Saunders JC, Young LM, Mahood RA, Jackson MP, Revill CH, Foster RJ, Smith DA, Ashcroft AE, Brockwell DJ, Radford SE. An in vivo platform for identifying inhibitors of protein aggregation. Nat Chem Biol. 2016 Feb; 12(2):94-101.
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Hayden MK, Lin MY, Lolans K, Weiner S, Blom D, Moore NM, Fogg L, Henry D, Lyles R, Thurlow C, Sikka M, Hines D, Weinstein RA. Prevention of colonization and infection by Klebsiella pneumoniae carbapenemase-producing enterobacteriaceae in long-term acute-care hospitals. Clin Infect Dis. 2015 Apr 15; 60(8):1153-61.
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