 Amitriptyline
"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
| Descriptor ID |
D000639
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| MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
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| Concept/Terms |
Domical- Domical
- APS Brand of Amitriptyline Hydrochloride
- Rhône-Poulenc Rorer Brand of Amitriptyline Hydrochloride
- Rhône Poulenc Rorer Brand of Amitriptyline Hydrochloride
Tryptine- Tryptine
- Amrad Brand of Amitriptyline Hydrochloride
Tryptizol- Tryptizol
- Cahill May Roberts Brand of Amitriptyline Embonate
- Merck Sharp & Dohme Brand of Amitriptyline Hydrochloride
- DDSA Brand of Amitriptyline Hydrochloride
- Tryptanol
- Merck Sharp & Dohme Brand of Amitriptyline Embonate
- Zeneca Brand of Amitriptyline Hydrochloride
- Elavil
- Cahill May Roberts Brand of Amitriptyline Hydrochloride
Amineurin- Amineurin
- Neuro Hexal Brand of Amitriptyline Hydrochloride
- Hexal Brand of Amitriptyline Hydrochloride
Amitrip- Amitrip
- Protea Brand of Amitriptyline Hydrochloride
Amitriptylin beta- Amitriptylin beta
- beta, Amitriptylin
- Betapharm Brand of Amitriptyline Hydrochloride
Amitriptylin Desitin- Amitriptylin Desitin
- Desitin, Amitriptylin
- Desitin Brand of Amitriptyline Hydrochloride
Amitriptylin RPh- Amitriptylin RPh
- RPh, Amitriptylin
- Rodleben Brand of Amitriptyline Hydrochloride
Amitriptylin-neuraxpharm- Amitriptylin-neuraxpharm
- Amitriptylin neuraxpharm
- Amitriptylinneuraxpharm
- neuraxpharm Brand of Amitriptyline Hydrochloride
Laroxyl- Laroxyl
- Roche Brand of Amitriptyline Hydrochloride
- Endep
- Alphapharm Brand of Amitriptyline Hydrochloride
Lentizol- Lentizol
- Parke Davis Brand of Amitriptyline Hydrochloride
Novoprotect- Novoprotect
- Merck Brand of Amitriptyline Hydrochloride
Saroten- Saroten
- Bayer Brand of Amitriptyline Hydrochloride
Sarotex- Sarotex
- Lundbeck Brand of Amitriptyline Hydrochloride
Syneudon- Syneudon
- Krewel Brand of Amitriptyline Hydrochloride
Triptafen- Triptafen
- Goldshield Brand of Amitriptyline Hydrochloride
Amitrol- Amitrol
- Douglas Brand of Amitriptyline Hydrochloride
Anapsique- Anapsique
- Psicofarma Brand of Amitriptyline Hydrochloride
Apo-Amitriptyline- Apo-Amitriptyline
- Apo Amitriptyline
- ApoAmitriptyline
- Apotex Brand of Amitriptyline Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in UAMS Profiles by year, and whether "Amitriptyline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1990 | 0 | 2 | 2 | | 1989 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Amitriptyline" by people in Profiles over the past ten years.
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Bayat A, Iavarone S, Miceli F, Jakobsen AV, Johannesen KM, Nikanorova M, Ploski R, Szymanska K, Flamini R, Cooper EC, Weckhuysen S, Taglialatela M, M?ller RS. Phenotypic and functional assessment of two novel KCNQ2 gain-of-function variants Y141N and G239S and effects of amitriptyline treatment. Neurotherapeutics. 2024 Jan; 21(1):e00296.
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Miceli F, Millevert C, Soldovieri MV, Mosca I, Ambrosino P, Carotenuto L, Schrader D, Lee HK, Riviello J, Hong W, Risen S, Emrick L, Amin H, Ville D, Edery P, de Bellescize J, Michaud V, Van-Gils J, Goizet C, Willemsen MH, Kleefstra T, M?ller RS, Bayat A, Devinsky O, Sands T, Korenke GC, Kluger G, Mefford HC, Brilstra E, Lesca G, Milh M, Cooper EC, Taglialatela M, Weckhuysen S. KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. EBioMedicine. 2022 Jul; 81:104130.
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Tang J, Landes RD. Some t-tests for N-of-1 trials with serial correlation. PLoS One. 2020; 15(2):e0228077.
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Lee HG, Grossman SK, Valdes-Rodriguez R, Berenato F, Korbutov J, Chan YH, Lavery MJ, Yosipovitch G. Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability. J Am Acad Dermatol. 2017 04; 76(4):760-761.
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Rosen JM, Alioto A, Saps M. Advances in Pain-Predominant Functional Gastrointestinal Disorders in the Adolescent. Adolesc Med State Art Rev. 2016; 27(1):34-56.
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