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Cisplatin

"Cisplatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.


expand / collapse publications
This graph shows the total number of publications written about "Cisplatin" by people in UAMS Profiles by year, and whether "Cisplatin" was a major or minor topic of these publications.
Bar chart showing 148 publications over 30 distinct years, with a maximum of 14 publications in 2007
To see the data from this visualization as text, click here.