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Ping-Ching Hsu

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCollege of Public Health, College of Provost
DivisionEnvironmental & Occupational Health
Address220 UAMS Campus Dr.
Mail Slot # 820
Little Rock AR 72205
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    Collapse Overview 

    Collapse Research Funds 
    Collapse research overview
    I am interested in investigating the metabolic impacts of tobacco use in the population by using metabolomics to better understand and predict toxins and metabolite markers in human as a result of tobacco use, as well as by using global methylation profiling to identify aberrant methylation changes responsive to environmental stimuli. My goal is to reduce health disparities in tobacco-related diseases by addressing the adverse health effects resulting directly from tobacco exposure and to further inform FDA rules and guidance that aim to reduce the impact of tobacco use on the nation’s health.

    Collapse research activities
    R13FD006611     (FAGAN, PEBBLES)Jan 1, 2019 - Dec 31, 2020
    U.S. Food and Drug Administration
    A Tobacco Regulatory Agenda for Vulnerable and Disparate Groups: Developing a Blueprint for Research, Policy, and Regulatory Standards
    Role: Co-Investigator

    U01DD001285     (NEMBHARD, WENDY N)Dec 1, 2018 - Aug 31, 2023
    CDC/NCBDD
    RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
    Role: Co-Investigator

    1U01DD001229-01     Sep 1, 2018 - Aug 7, 2023
    Center for Disease Control and Prevention
    Component A: Arkansas Proposal to participate in the Birth Defect Study to Evaluate Pregnancy exposureS (BD-STEPS II)
    Role: Co-Investigator

         (HSU, PING-CHING)Sep 1, 2018 - Aug 30, 2019
    UAMS Arkansas Center for Health Disparities (ARCHD) Pilot Award
    Understanding the Factors Influencing Exposures from Tobacco Usage among Young Adults in the Minority Communities
    Role: Principal Investigator

    U54MD002329-11     Sep 23, 2017 - Apr 30, 2018
    National Institute on Minority Health and Health Disparities
    Project 1: Reducing Tobacco Smoke Exposures among Low Income Children and Women Caregivers in the Arkansas Delta Region.
    Role: Co-Investigator

    U19CA157345     (HSU, PING-CHING)Sep 1, 2017 - Aug 31, 2018
    NIH/Nat. Cancer Institute - Pass Through: The Ohio State University
    Models for Tobacco Product Evaluation – Project 4
    Role: Principal Investigator

         (HSU, PING-CHING)Jul 1, 2017 - Jun 30, 2018
    UAMS 2017 Center for the Study of Tobacco Pilot Award
    Metabolomic Profiling from the Arkansas Cardiovascular Health Examination Survey (ARCHES)
    Role: Principal Investigator

         (HSU, PING-CHING)Jul 1, 2017 - Jun 30, 2018
    UAMS Cancer Prevention and Population Sciences 2017 Pilot Award
    Disparities in Epigenetic Profiles in Arkansas Women with High and Low Poverty Counties: A Validation Study
    Role: Principal Investigator

         (HSU, PING-CHING)Feb 1, 2017 - Jan 31, 2018
    UAMS Cancer Institute 2017 Seeds of Science Pilot Award
    Metabolomic Profiling from the Arkansas Cardiovascular Health Examination Survey (ARCHES)
    Role: Principal Investigator

    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - Mar 31, 2020
    NIH/NIGMS
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator

    U54MD002329     (RACZYNSKI, JAMES M)Sep 30, 2007 - Apr 30, 2022
    NIH/NIMHD
    Arkansas Center for Health Disparities (ARCHD): An NIMHD COE
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Tseng ZF, Hsu PI, Peng NJ, Kao SS, Tsay FW, Cheng JS, Chen WC, Tsai KF, Tang SY, Chuah SK, Shie CB. Omeprazole vs famotidine for the prevention of gastroduodenal injury in high-risk users of low-dose aspirin: A randomized controlled trial. J Chin Med Assoc. 2021 Jan 01; 84(1):19-24. PMID: 33230059.
      View in: PubMed
    2. Lin TF, Wu DC, Tsay FW, Tsai KW, Tsai TJ, Peng NJ, Kao SS, Chen WC, Chen YH, Hsu PI. Reverse hybrid therapy achieves a similar eradication rate as standard hybrid therapy for Helicobacter pylori infection. J Chin Med Assoc. 2020 Mar; 83(3):233-237. PMID: 31934941.
      View in: PubMed
    3. Sung CC, Horng JH, Siao SH, Chyuan IT, Tsai HF, Chen PJ, Hsu PN. Asialo GM1-positive liver-resident CD8 T cells that express CD44 and LFA-1 are essential for immune clearance of hepatitis B virus. Cell Mol Immunol. 2020 Feb 28. PMID: 32111985.
      View in: PubMed
    4. Chuah YY, Hsu PI, Tsai WL, Yu HC, Tsay FW, Chen WC, Lin KH, Lee YY, Wang HM. Short-term vasoactive agent treatment driven by physicians' preference in acute esophageal variceal bleeding in a tertiary center. PeerJ. 2019; 7:e7913. PMID: 31720102.
      View in: PubMed
    5. Hsu PC, Jablons DM, Yang CT, You L. Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC). Int J Mol Sci. 2019 Aug 05; 20(15). PMID: 31387256.
      View in: PubMed
    6. Chen YH, Yu HC, Lin KH, Lin HS, Hsu PI. Prevalence and risk factors for Barrett's esophagus in Taiwan. World J Gastroenterol. 2019 Jul 07; 25(25):3231-3241. PMID: 31333314.
      View in: PubMed
    7. Hsu PC, Tian B, Yang YL, Wang YC, Liu S, Urisman A, Yang CT, Xu Z, Jablons DM, You L. Cucurbitacin E inhibits the Yes-associated protein signaling pathway and suppresses brain metastasis of human non-small cell lung cancer in a murine model. Oncol Rep. 2019 Aug; 42(2):697-707. PMID: 31233205.
      View in: PubMed
    8. Chen DY, Hsu PN, Tang CH, Claxton L, Valluri S, Gerber RA. Tofacitinib in the treatment of moderate-to-severe rheumatoid arthritis: a cost-effectiveness analysis compared with adalimumab in Taiwan. J Med Econ. 2019 Aug; 22(8):777-787. PMID: 30982378.
      View in: PubMed
    9. Chiang HH, Wu DC, Hsu PI, Kuo CH, Tai WC, Yang SC, Wu KL, Yao CC, Tsai CE, Liang CM, Wang YK, Wang JW, Huang CF, Chuah SK. Clinical efficacy of 60-mg dexlansoprazole and 40-mg esomeprazole after 24 weeks for the on-demand treatment of gastroesophageal reflux disease grades A and B: a prospective randomized trial. Drug Des Devel Ther. 2019; 13:1347-1356. PMID: 31118571.
      View in: PubMed
    10. Chen WC, Hsin IF, Chen PH, Hsu PI, Wang YP, Cheng JS, Lin HS, Hou MC, Lee FY. Addition of Carvedilol to Gastric Variceal Obturation Does Not Decrease Recurrence of Gastric Variceal Bleeding in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2019 10; 17(11):2356-2363.e2. PMID: 30772583.
      View in: PubMed
    11. Liao HJ, Tsai HF, Wu CS, Chyuan IT, Hsu PN. TRAIL inhibits RANK signaling and suppresses osteoclast activation via inhibiting lipid raft assembly and TRAF6 recruitment. Cell Death Dis. 2019 01 28; 10(2):77. PMID: 30692521.
      View in: PubMed
    12. Ou DL, Lin YY, Hsu CL, Lin YY, Chen CW, Yu JS, Miaw SC, Hsu PN, Cheng AL, Hsu C. Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma. Liver Cancer. 2019 May; 8(3):155-171. PMID: 31192153.
      View in: PubMed
    13. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):51-60. PMID: 27628308.
      View in: PubMed
    14. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Metabolomic profiles of current cigarette smokers. Mol Carcinog. 2017 02; 56(2):594-606. PMID: 27341184.
      View in: PubMed
    15. Weng DY, Chen J, Taslim C, Hsu PC, Marian C, David SP, Loffredo CA, Shields PG. Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog. 2016 10; 55(10):1424-37. PMID: 26294040.
      View in: PubMed
    16. Hsu PI, Lai KH, Cheng JS, Kao SS, Li YR, Sun WC, Chen WC, Lin KH, Shin CA, Chiang PH, Li YD, Ou WT, Chen HC, Yu HC. Prevention of acute exacerbation of chronic hepatitis B infection in cancer patients receiving chemotherapy in a hepatitis B virus endemic area. Hepatology. 2015 Aug; 62(2):387-96. PMID: 26041578.
      View in: PubMed
    17. Wang FW, Chuang HY, Tu MS, King TM, Wang JH, Hsu CW, Hsu PI, Chen WC. Prevalence and risk factors of asymptomatic colorectal diverticulosis in Taiwan. BMC Gastroenterol. 2015 Apr 01; 15:40. PMID: 25888375.
      View in: PubMed
    18. Liao HJ, Chyuan IT, Wu CS, Lin SW, Chen KH, Tsai HF, Hsu PN. Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice. Rheumatology (Oxford). 2015 Jul; 54(7):1317-26. PMID: 25602062.
      View in: PubMed
    19. Wang PY, Chen HP, Chen A, Tsay FW, Lai KH, Kao SS, Chen WC, Kuo CH, Peng NJ, Tseng HH, Hsu PI. Impact of blood type, functional polymorphism (T-1676C) of the COX-1 gene promoter and clinical factors on the development of peptic ulcer during cardiovascular prophylaxis with low-dose aspirin. Biomed Res Int. 2014; 2014:616018. PMID: 25243161.
      View in: PubMed
    20. Hsu PI, Wu DC, Chen WC, Tseng HH, Yu HC, Wang HM, Kao SS, Lai KH, Chen A, Tsay FW. Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. Antimicrob Agents Chemother. 2014 Oct; 58(10):5936-42. PMID: 25070099.
      View in: PubMed
    21. Tzeng HT, Tsai HF, Chyuan IT, Liao HJ, Chen CJ, Chen PJ, Hsu PN. Tumor necrosis factor-alpha induced by hepatitis B virus core mediating the immune response for hepatitis B viral clearance in mice model. PLoS One. 2014; 9(7):e103008. PMID: 25047809.
      View in: PubMed
    22. Chen WC, Chen YH, Hsu PI, Tsay FW, Chan HH, Cheng JS, Lai KH. Gastrointestinal hemorrhage in warfarin anticoagulated patients: incidence, risk factor, management, and outcome. Biomed Res Int. 2014; 2014:463767. PMID: 24987683.
      View in: PubMed
    23. Tsai WL, Lai KH, Liang HL, Hsu PI, Chan HH, Chen WC, Yu HC, Tsay FW, Wang HM, Tsai HC, Cheng JS. Hepatic arterial infusion chemotherapy for patients with huge unresectable hepatocellular carcinoma. PLoS One. 2014; 9(5):e92784. PMID: 24824520.
      View in: PubMed
    24. Chu TH, Chan HH, Kuo HM, Liu LF, Hu TH, Sun CK, Kung ML, Lin SW, Wang EM, Ma YL, Cheng KH, Lai KH, Wen ZH, Hsu PI, Tai MH. Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. Oncotarget. 2014 Mar 30; 5(6):1475-90. PMID: 24721996.
      View in: PubMed
    25. Huang YW, Hsu CK, Lin SC, Wei SC, Hu JT, Chang HY, Liang CW, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced toll-like receptor 9 expression on peripheral CD14+ monocytes of chronic hepatitis B patients and its restoration by effective therapy. Antivir Ther. 2014; 19(7):637-43. PMID: 24622882.
      View in: PubMed
    26. Wang HM, Chan HH, Wu MJ, Hsu PI, Lin CK, Yu HC, Chen WC, Tsai WL, Tsay FW, Tsai TJ. Not only hysterectomy but also cesarean section can predict incomplete flexible sigmoidoscopy among patients with prior abdominal or pelvic surgery. J Chin Med Assoc. 2014 Mar; 77(3):122-7. PMID: 24388006.
      View in: PubMed
    27. Lin KH, Yu HC, Hsu PI, Tsai WL, Chen WC, Lin CK, Chan HH, Tsay FW, Lai KH. Baseline high viral load and unfavorable patterns of alanine aminotransferase change predict virological relapse in patients with chronic hepatitis C genotype 1 or 2 obtaining rapid virological response during antiviral therapy. Hepat Mon. 2013; 13(10):e11892. PMID: 24348635.
      View in: PubMed
    28. Yu HC, Lin KH, Hsu PI, Tsay FW, Wang HM, Tsai TJ, Lai KH. Real-world application of the roadmap model in chronic hepatitis B patients with telbivudine therapy. Clin Ther. 2013 Sep; 35(9):1386-99. PMID: 24054706.
      View in: PubMed
    29. Tzeng HT, Hsu PN, Chen PJ. Immunocompetent nontransgenic mouse models for studying hepatitis B virus immune responses. J Gastroenterol Hepatol. 2013 Aug; 28 Suppl 1:116-9. PMID: 23855306.
      View in: PubMed
    30. Huang YW, Lin SC, Wei SC, Hu JT, Chang HY, Huang SH, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy. Antivir Ther. 2013; 18(7):877-84. PMID: 23744559.
      View in: PubMed
    31. Hsu PC, Zhou B, Zhao Y, Ressom HW, Cheema AK, Pickworth W, Shields PG. Feasibility of identifying the tobacco-related global metabolome in blood by UPLC-QTOF-MS. J Proteome Res. 2013 Feb 01; 12(2):679-91. PMID: 23240883.
      View in: PubMed
    32. Lin CJ, Rao YK, Hung CL, Feng CL, Lane HY, Tzeng DT, Hsu PN, Lai CH, Tzeng YM. Inhibition of Helicobacter pylori CagA-Induced Pathogenesis by Methylantcinate B from Antrodia camphorata. Evid Based Complement Alternat Med. 2013; 2013:682418. PMID: 23431343.
      View in: PubMed
    33. Tsai TJ, Lai KH, Lin CK, Chan HH, Wang EM, Tsai WL, Cheng JS, Yu HC, Chen WC, Hsu PI. The relationship between gallbladder status and recurrent biliary complications in patients with choledocholithiasis following endoscopic treatment. J Chin Med Assoc. 2012 Nov; 75(11):560-6. PMID: 23158033.
      View in: PubMed
    34. Kuo CH, Hsu PI, Kuo FC, Wang SS, Hu HM, Liu CJ, Chuah SK, Chen YH, Hsieh MC, Wu DC, Tseng HH. Comparison of 10 day bismuth quadruple therapy with high-dose metronidazole or levofloxacin for second-line Helicobacter pylori therapy: a randomized controlled trial. J Antimicrob Chemother. 2013 Jan; 68(1):222-8. PMID: 22984204.
      View in: PubMed
    35. Wang HM, Lo GH, Chen WC, Hsu PI, Yu HC, Lin CK, Chan HH, Tsai WL, Tsay FW, Liu TP, Wang EM, Lai KH. Efficacy of transient elastography in screening for large esophageal varices in patients with suspicious or proven liver cirrhosis. J Dig Dis. 2012 Aug; 13(8):430-8. PMID: 22788929.
      View in: PubMed
    36. Tzeng HT, Tsai HF, Liao HJ, Lin YJ, Chen L, Chen PJ, Hsu PN. PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model. PLoS One. 2012; 7(6):e39179. PMID: 22761734.
      View in: PubMed
    37. Yen ML, Hsu PN, Liao HJ, Lee BH, Tsai HF. TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation. PLoS One. 2012; 7(6):e38048. PMID: 22719861.
      View in: PubMed
    38. Chen TC, Wu JJ, Chang WP, Hsu PN, Hsieh ST, Shyu BC. Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis. J Biomed Sci. 2012 May 30; 19:55. PMID: 22646813.
      View in: PubMed
    39. Kao JT, Lai HC, Tsai SM, Lin PC, Chuang PH, Yu CJ, Cheng KS, Su WP, Hsu PN, Peng CY, Wu YY. Rather than interleukin-27, interleukin-6 expresses positive correlation with liver severity in naïve hepatitis B infection patients. Liver Int. 2012 Jul; 32(6):928-36. PMID: 22230324.
      View in: PubMed
    40. Wu DC, Hsu PI, Tseng HH, Tsay FW, Lai KH, Kuo CH, Wang SW, Chen A. Helicobacter pylori infection: a randomized, controlled study comparing 2 rescue therapies after failure of standard triple therapies. Medicine (Baltimore). 2011 May; 90(3):180-185. PMID: 21512411.
      View in: PubMed
    41. Hu CY, Chang SK, Wu CS, Tsai WI, Hsu PN. Galectin-3 gene (LGALS3) +292C allele is a genetic predisposition factor for rheumatoid arthritis in Taiwan. Clin Rheumatol. 2011 Sep; 30(9):1227-33. PMID: 21475983.
      View in: PubMed
    42. Huang SC, Tsai HF, Tzeng HT, Liao HJ, Hsu PN. Lipid raft assembly and Lck recruitment in TRAIL costimulation mediates NF-?B activation and T cell proliferation. J Immunol. 2011 Jan 15; 186(2):931-9. PMID: 21160038.
      View in: PubMed
    43. Hsu PI, Lai KH, Liu CP. Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis. Gastroenterology. 2011 Mar; 140(3):791-8. PMID: 21144850.
      View in: PubMed
    44. Hsu PN, Yang TC, Kao JT, Cheng KS, Lee YJ, Wang YM, Hsieh CT, Lin CW, Wu YY. Increased PD-1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma. Liver Int. 2010 Oct; 30(9):1379-86. PMID: 20738778.
      View in: PubMed
    45. Lin WC, Tsai HF, Kuo SH, Wu MS, Lin CW, Hsu PI, Cheng AL, Hsu PN. Translocation of Helicobacter pylori CagA into Human B lymphocytes, the origin of mucosa-associated lymphoid tissue lymphoma. Cancer Res. 2010 Jul 15; 70(14):5740-8. PMID: 20587516.
      View in: PubMed
    46. Lin YJ, Huang LR, Yang HC, Tzeng HT, Hsu PN, Wu HL, Chen PJ, Chen DS. Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9340-5. PMID: 20439715.
      View in: PubMed
    47. Hsu PI, Chen CH, Hsiao M, Wu DC, Lin CY, Lai KH, Lu PJ. Diagnosis of gastric malignancy using gastric juice alpha1-antitrypsin. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):405-11. PMID: 20086110.
      View in: PubMed
    48. Wang FW, Tu MS, Chuang HY, Yu HC, Cheng LC, Hsu PI. Erosive esophagitis in asymptomatic subjects: risk factors. Dig Dis Sci. 2010 May; 55(5):1320-4. PMID: 19685186.
      View in: PubMed
    49. Tsai TJ, Lai KH, Hsu PI, Tsai CC, Fu TY. Gallbladder cancer manifesting as recurrent common bile duct stone and duodenal ulcer bleeding. J Chin Med Assoc. 2009 Aug; 72(8):434-7. PMID: 19687000.
      View in: PubMed
    50. Chan HH, Lai KH, Lin CK, Tsai WL, Peng NJ, Hsu PI, Lo GH, Wei MC, Wang EM, Chang HW. Impact of food on hepatic clearance of patients after endoscopic sphincterotomy. J Chin Med Assoc. 2009 Jan; 72(1):10-4. PMID: 19181591.
      View in: PubMed
    51. Chen TA, Tsao YC, Chen A, Lo GH, Lin CK, Yu HC, Cheng LC, Hsu PI, Tsai WL. Effect of intravenous albumin on endotoxin removal, cytokines, and nitric oxide production in patients with cirrhosis and spontaneous bacterial peritonitis. Scand J Gastroenterol. 2009; 44(5):619-25. PMID: 19191184.
      View in: PubMed
    52. Peng NJ, Lai KH, Lo GH, Hsu PI. Comparison of noninvasive diagnostic tests for Helicobacter pylori infection. Med Princ Pract. 2009; 18(1):57-61. PMID: 19060493.
      View in: PubMed
    53. Chan HH, Lai KH, Lin CK, Tsai WL, Lo GH, Hsu PI, Wei MC, Wang EM. Effect of somatostatin in the prevention of pancreatic complications after endoscopic retrograde cholangiopancreatography. J Chin Med Assoc. 2008 Dec; 71(12):605-9. PMID: 19114324.
      View in: PubMed
    54. Wang HM, Lo GH, Hsu PI, Lin CK, Chan HH, Chen WC, Lai KH, Wang BW, Lin SL. Nodular regenerative hyperplasia of the liver. J Chin Med Assoc. 2008 Oct; 71(10):523-7. PMID: 18955187.
      View in: PubMed
    55. Lo GH, Chen WC, Lin CK, Tsai WL, Chan HH, Chen TA, Yu HC, Hsu PI, Lai KH. Improved survival in patients receiving medical therapy as compared with banding ligation for the prevention of esophageal variceal rebleeding. Hepatology. 2008 Aug; 48(2):580-7. PMID: 18666235.
      View in: PubMed
    56. Kuo SH, Yeh PY, Chen LT, Wu MS, Lin CW, Yeh KH, Tzeng YS, Chen JY, Hsu PN, Lin JT, Cheng AL. Overexpression of B cell-activating factor of TNF family (BAFF) is associated with Helicobacter pylori-independent growth of gastric diffuse large B-cell lymphoma with histologic evidence of MALT lymphoma. Blood. 2008 Oct 01; 112(7):2927-34. PMID: 18628489.
      View in: PubMed
    57. Yu HC, Lo GH, Lai KH, Hsu PI, Chen IS, Hsieh PP. Adenomyoma of the jejunum --- a rare cause of gastrointestinal bleeding. J Chin Med Assoc. 2008 Feb; 71(2):96-9. PMID: 18290255.
      View in: PubMed
    58. Wu CS, Hu CY, Hsu PN. Anti-SSB/La antibody is negatively associated with HLA-DR2 in chronic hepatitis C infection. Clin Rheumatol. 2008 Mar; 27(3):365-8. PMID: 17992468.
      View in: PubMed
    59. Chou MY, Hsu PI, Chou SL, Chou YM, Wang FW, Hsueh KC, Chen LK, Hwang SJ, Tu MS. Factors related to incomplete flexible sigmoidoscopy among adult Chinese in Taiwan. J Chin Med Assoc. 2007 Sep; 70(9):361-6. PMID: 17908649.
      View in: PubMed
    60. Chen TA, Lo GH, Lin CK, Lai KH, Wong HY, Yu HC, Hsu PI, Chen HH, Tsai WL, Chen WC. Acute pancreatitis-associated acute gastrointestinal mucosal lesions: incidence, characteristics, and clinical significance. J Clin Gastroenterol. 2007 Jul; 41(6):630-4. PMID: 17577121.
      View in: PubMed
    61. Wu YY, Tsai HF, Lin WC, Hsu PI, Shun CT, Wu MS, Hsu PN. Upregulation of CCL20 and recruitment of CCR6+ gastric infiltrating lymphocytes in Helicobacter pylori gastritis. Infect Immun. 2007 Sep; 75(9):4357-63. PMID: 17562763.
      View in: PubMed
    62. Chen WC, Lo GH, Tsai WL, Hsu PI, Lin CK, Lai KH. Emergency endoscopic variceal ligation versus somatostatin for acute esophageal variceal bleeding. J Chin Med Assoc. 2006 Feb; 69(2):60-7. PMID: 16570572.
      View in: PubMed
    63. Hsu PI, Lai KH, Lin CK, Chen WC, Yu HC, Cheng JS, Tsay FW, Wu CJ, Lo CC, Tseng HH, Yamaoka Y, Chen JL, Lo GH. A prospective randomized trial of esomeprazole- versus pantoprazole-based triple therapy for Helicobacter pylori eradication. Am J Gastroenterol. 2005 Nov; 100(11):2387-92. PMID: 16279889.
      View in: PubMed
    64. Tsai WL, Lai KH, Lin CK, Chan HH, Lo CC, Hsu PI, Chen WC, Cheng JS, Lo GH. Composition of common bile duct stones in Chinese patients during and after endoscopic sphincterotomy. World J Gastroenterol. 2005 Jul 21; 11(27):4246-9. PMID: 16015699.
      View in: PubMed
    65. Hung CH, Li CY, Lai YS, Hsu PC, Hua YM, Yang KD. Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma. Pediatr Allergy Immunol. 2005 Jun; 16(4):306-9. PMID: 15943593.
      View in: PubMed
    66. Hsu PI, Jwo JJ, Tseng HH, Lai KH, Lo GH, Lo CC, Wu CJ, Chuah SK, Hwang IR, Chen JL, Chen YS, Chen A. Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk. World J Gastroenterol. 2005 May 14; 11(18):2796-801. PMID: 15884126.
      View in: PubMed
    67. Lu H, Hsu PI, Graham DY, Yamaoka Y. Duodenal ulcer promoting gene of Helicobacter pylori. Gastroenterology. 2005 Apr; 128(4):833-48. PMID: 15825067.
      View in: PubMed
    68. Chou AH, Tsai HF, Wu YY, Hu CY, Hwang LH, Hsu PI, Hsu PN. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway. J Immunol. 2005 Feb 15; 174(4):2160-6. PMID: 15699147.
      View in: PubMed
    69. Lin CP, Yu HC, Cheng JS, Lai KH, Lo GH, Hsu PI, Lin CK, Chen HH, Lo CC, Liang HL, Tseng HH. Clinical effects of intra-arterial infusion chemotherapy with cisplatin, mitomycin C, leucovorin and 5-flourouracil for unresectable advanced hepatocellular carcinoma. J Chin Med Assoc. 2004 Dec; 67(12):602-10. PMID: 15779483.
      View in: PubMed
    70. Lo GH, Chen WC, Chen MH, Tsai WL, Chan HH, Cheng LC, Hsu PI, Lai KH. The characteristics and the prognosis for patients presenting with actively bleeding esophageal varices at endoscopy. Gastrointest Endosc. 2004 Nov; 60(5):714-20. PMID: 15557947.
      View in: PubMed
    71. Tsai CS, Hsu PC, Huang GS, Lin TC, Hong GJ, Shih CM, Li CY. Midazolam attenuates adenosine diphosphate-induced P-selectin expression and platelet-leucocyte aggregation. Eur J Anaesthesiol. 2004 Nov; 21(11):871-6. PMID: 15717703.
      View in: PubMed
    72. Chen WC, Lo GH, Lai KH, Cheng JS, Hsu PI, Lin CK. Development of hepatocellular carcinoma after successful management of esophageal variceal bleeding. J Chin Med Assoc. 2004 Nov; 67(11):557-64. PMID: 15720069.
      View in: PubMed
    73. Huang GS, Li CY, Hsu PC, Tsai CS, Lin TC, Wong CS. Sevoflurane anesthesia attenuates adenosine diphosphate-induced P-selectin expression and platelet-leukocyte conjugate formation. Anesth Analg. 2004 Oct; 99(4):1121-6, table of contents. PMID: 15385361.
      View in: PubMed
    74. Wu YY, Tsai HF, Lin WC, Chou AH, Chen HT, Yang JC, Hsu PI, Hsu PN. Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells. World J Gastroenterol. 2004 Aug 15; 10(16):2334-9. PMID: 15285015.
      View in: PubMed
    75. Wu CJ, Hsu PI, Lo GH, Lo CC, Lin CK, Shie CB, Peng NJ, Tseng HH, Jou HS, Tsai PM, Chen A, Chen JL, Lai KH. Comparison of cetraxate-based and pantoprazole-based triple therapies in the treatment of Helicobacter pylori infection. J Chin Med Assoc. 2004 Apr; 67(4):161-7. PMID: 15244013.
      View in: PubMed
    76. Lo GH, Chen WC, Chen MH, Lin CP, Lo CC, Hsu PI, Cheng JS, Lai KH. Endoscopic ligation vs. nadolol in the prevention of first variceal bleeding in patients with cirrhosis. Gastrointest Endosc. 2004 Mar; 59(3):333-8. PMID: 14997127.
      View in: PubMed
    77. Tsai HF, Lai JJ, Chou AH, Wang TF, Wu CS, Hsu PN. Induction of costimulation of human CD4 T cells by tumor necrosis factor-related apoptosis-inducing ligand: possible role in T cell activation in systemic lupus erythematosus. Arthritis Rheum. 2004 Feb; 50(2):629-39. PMID: 14872508.
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    78. Lo CC, Hsu PI, Lo GH, Tseng HH, Chen HC, Hsu PN, Lin CK, Chan HH, Tsai WL, Chen WC, Wang EM, Lai KH. Endoscopic banding ligation can effectively resect hyperplastic polyps of stomach. World J Gastroenterol. 2003 Dec; 9(12):2805-8. PMID: 14669338.
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    79. Chou NH, Mok KT, Wang BW, Chang HT, Hsu PI. Risk factors of mortality after surgical treatment of intestinal obstruction in patients having prior laparotomy for non-malignancy. J Chin Med Assoc. 2003 Dec; 66(12):741-6. PMID: 15015824.
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    80. Li CY, Tsai CS, Hsu PC, Chueh SH, Wong CS, Ho ST. Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: possible mechanisms for its effect on inflammation. Anesth Analg. 2003 Nov; 97(5):1312-6. PMID: 14570645.
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    81. Wang YY, Lo GH, Lai KH, Cheng JS, Lin CK, Hsu PI. Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma. J Chin Med Assoc. 2003 Oct; 66(10):593-8. PMID: 14703276.
      View in: PubMed
    82. Yeh CL, Lai KH, Lo GH, Lin CK, Hsu PI, Chan HH, Tsai WL, Lin CP. Endoscopic treatment in a patient with obstructive jaundice caused by pancreatic pseudocyst. J Chin Med Assoc. 2003 Sep; 66(9):555-9. PMID: 14649681.
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    83. Li CY, Tsai CS, Hsu PC, Wu CT, Wong CS, Ho ST. Dobutamine modulates lipopolysaccharide-induced macrophage inflammatory protein-1alpha and interleukin-8 production in human monocytes. Anesth Analg. 2003 Jul; 97(1):210-5, table of contents. PMID: 12818968.
      View in: PubMed
    84. Li CY, Tsai CS, Chueh SH, Hsu PC, Wang JY, Wong CS, Ho ST. Dobutamine inhibits monocyte chemoattractant protein-1 production and chemotaxis in human monocytes. Anesth Analg. 2003 Jul; 97(1):205-9, table of contents. PMID: 12818967.
      View in: PubMed
    85. Chou YC, Hsu PI, Lai KH, Lo CC, Chan HH, Lin CP, Chen WC, Shie CB, Wang EM, Chou NH, Chen W, Lo GH. A prospective, randomized trial of endoscopic hemoclip placement and distilled water injection for treatment of high-risk bleeding ulcers. Gastrointest Endosc. 2003 Mar; 57(3):324-8. PMID: 12612510.
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    86. Lu JY, Chen HC, Chu RY, Lin TC, Hsu PI, Huang MS, Tseng CJ, Hsiao M. Establishment of red fluorescent protein-tagged HeLa tumor metastasis models: determination of DsRed2 insertion effects and comparison of metastatic patterns after subcutaneous, intraperitoneal, or intravenous injection. Clin Exp Metastasis. 2003; 20(2):121-33. PMID: 12705633.
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    87. Lo GH, Chen WC, Chen MH, Hsu PI, Lin CK, Tsai WL, Lai KH. Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding. Gastroenterology. 2002 Sep; 123(3):728-34. PMID: 12198699.
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    88. Lin CK, Wang ZS, Lai KH, Lo GH, Hsu PI. Gastrointestinal mucosal lesions in patients with acute pancreatitis. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jun; 65(6):275-8. PMID: 12201568.
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    89. Lin CK, Hsu PI, Lai KH, Lo GH, Tseng HH, Lo CC, Peng NJ, Chen HC, Jou HS, Huang WK, Chen JL, Hsu PN. One-week quadruple therapy is an effective salvage regimen for Helicobacter pylori infection in patients after failure of standard triple therapy. J Clin Gastroenterol. 2002 May-Jun; 34(5):547-51. PMID: 11960067.
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    90. Lai KH, Lo GH, Lin CK, Hsu PI, Chan HH, Cheng JS, Wang EM. Do patients with recurrent choledocholithiasis after endoscopic sphincterotomy benefit from regular follow-up? Gastrointest Endosc. 2002 Apr; 55(4):523-6. PMID: 11923765.
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    91. Lai KH, Peng NJ, Lo GH, Lin CK, Chan HH, Hsu PI, Cheng JS, Wang YY. Does a fatty meal improve hepatic clearance in patients after endoscopic sphincterotomy? J Gastroenterol Hepatol. 2002 Mar; 17(3):337-41. PMID: 11982706.
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    92. Yeh GC, Chen JC, Tsai HC, Wu HH, Lin CY, Hsu PC, Peng YC. Amphetamine inhibits the N-methyl-D-aspartate receptor-mediated responses by directly interacting with the receptor/channel complex. J Pharmacol Exp Ther. 2002 Mar; 300(3):1008-16. PMID: 11861810.
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    93. Chan HH, Lai KH, Lo GH, Cheng JS, Huang JS, Hsu PI, Lin CK, Wang EM. The clinical and cholangiographic picture of hepatic clonorchiasis. J Clin Gastroenterol. 2002 Feb; 34(2):183-6. PMID: 11782616.
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    94. Chen JY, Hsu PC, Hsu IL, Yeh GC. Sequential up-regulation of the c-fos, c-jun and bax genes in the cortex, striatum and cerebellum induced by a single injection of a low dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6 mice. Neurosci Lett. 2001 Nov 13; 314(1-2):49-52. PMID: 11698144.
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