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Ping-Ching Hsu

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCPH | Environmental Health Sciences
DivisionEnvironmental Health Sciences
Address220 UAMS Campus Dr.
Mail Slot # 820
Little Rock AR 72205
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    Collapse Overview 

    Collapse Affiliation 
    Collapse member of
    Metabolomics Society
    American Association for Cancer Research (AACR)
    Metabolomics Association of North America (MANA)

    Collapse Teaching 

    Collapse Research 
    Collapse research overview
    My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.

    Collapse research activities and funding
    1R01DA061863-01A1     (HSU, PING-CHING)Jul 1, 2025 - Mar 31, 2030
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University
    Long-term effects of electronic cigarettes on brain health
    Role: Principal Investigator
    5R01DA061863-02     (HSU, PING-CHING)Jul 1, 2025 - Mar 31, 2030
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University
    Long-term effects of electronic cigarettes on brain health
    Role: Principal Investigator
    5R01DA061863-03     (HSU, PING-CHING)Jul 1, 2025 - Mar 31, 2030
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University
    Long-term effects of electronic cigarettes on brain health
    Role: Principal Investigator
    5R01DA061863-04     (HSU, PING-CHING)Jul 1, 2025 - Mar 31, 2030
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University
    Long-term effects of electronic cigarettes on brain health
    Role: Principal Investigator
    5R01DA061863-05     (HSU, PING-CHING)Jul 1, 2025 - Mar 31, 2030
    NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University
    Long-term effects of electronic cigarettes on brain health
    Role: Principal Investigator
    1U24ES037082     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    1U24ES037082-01     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    5U24ES037082     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    5U24ES037082-02     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    5U24ES037082-03     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    5U24ES037082-04     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    5U24ES037082-05     (HSU, PING-CHING)Dec 19, 2024 - Nov 30, 2029
    NIH/Nat. Inst. of Environmental Health Sciences
    Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs
    Role: Principal Investigator
    HT94252310924     (HSU, PING-CHING)Sep 1, 2023 - Aug 31, 2026
    US Department of Defense - Pass Through: University of Texas Southwestern Medical Center
    Modulation effect of folate on the association between inorganic arsenic and aggressive prostate cancer
    Role: Principal Investigator
    W81XWH-21-1-0226     (Ping-Ching Hsu)Apr 1, 2021 - Mar 31, 2024
    US Department of Defense
    Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men
    Role: Principal Investigator
    W81XWH2110226     (HSU, PING-CHING)Apr 1, 2021 - Mar 31, 2024
    US Department of Defense
    Metabolomics of menthol cigarette smoking and risk for aggressive prostate cancer among African-American men
    Role: Principal Investigator
         (Hsu/Makhoul/Allen)Apr 1, 2021 - Mar 31, 2022
    Winthrop P. Rockefeller Team Science Pilot Award
    Feasibility study to improve the assessment of cancer treatment-related cognitive impairment.
    Role: Principal Investigator
    U01DD001285     (NEMBHARD, WENDY N)Dec 1, 2018 - Aug 31, 2023
    NIH
    RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth
    Role: Co-Investigator
    R15CA231510     (HSU, PING-CHING)Sep 6, 2018 - May 31, 2022
    NIH/Nat. Cancer Institute
    Evaluating Impact of Diet and Fresh Food Access on Aggressive Prostate Cancer using Multi-Level Modeling
    Role: Principal Investigator
    1U01DD001229-01     Sep 1, 2018 - Aug 7, 2023
    Center for Disease Control and Prevention
    Component A: Arkansas Proposal to participate in the Birth Defect Study to Evaluate Pregnancy exposureS (BD-STEPS II)
    Role: Co-Investigator
    CI-Tobacco Prevention Internal Award     (ORLOFF, MOHAMMED S)Jul 1, 2017 - Jun 30, 2019
    UAMS Internal Research Awards
    Interaction of lug microbiome and tobaccorelated insults in lung cancer
    Role: Principal Investigator
    CI-TobaccoPreventionInternalAward     (ORLOFF, MOHAMMED S)Jul 1, 2017 - Jun 30, 2019
    UAMS Internal Research Awards
    Interaction of lug microbiome and tobaccorelated insults in lung cancer
    Role: Principal Investigator
    CPPS Pilot Award 2017     (QUICK, CHARLES M)Jul 1, 2017 - Dec 31, 2018
    UAMS College of Medicine
    Cancer Prevention and Population Sciences Program
    Role: Principal Investigator
    CPPSPilotAward2017     (QUICK, CHARLES M)Jul 1, 2017 - Dec 31, 2018
    UAMS College of Medicine
    Cancer Prevention and Population Sciences Program
    Role: Principal Investigator
    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - May 31, 2025
    NIH
    Center for Studies of Host Response to Cancer Therapy
    Role Description: The goal of the study is to examine whether type of cigarette smoked contribute to racial disparity in prostate cancer.
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Huang JK, Chuang YS, Wu PH, Lin JR, Kuo MC, Chiu YW, Hsu PC, Salihovic S, Lin YT. Perfluoroalkyl substance levels are associated with filter type and nutritional status in hemodialysis patients. Ecotoxicol Environ Saf. 2026 Jan 01; 309:119521. PMID: 41380604.
      View in: PubMed
    2. Wu PJ, Tsay FW, Wu DC, Yang JC, Chuah SK, Chen KY, Chen CL, Lee CL, Shih CA, Liu YH, Shiu SI, Tai WC, Kuo CH, Lei WY, Kao SS, Tsai TJ, Feng IC, Koseki M, Hsu PI, Sheu MJ. Sequential changes of antibiotic resistances of Helicobacter pylori in Taiwan from 2019 to 2024. World J Gastroenterol. 2025 Oct 21; 31(39):111380. PMID: 41180781.
      View in: PubMed
    3. Lai CS, Hsu WC, Chen JR, Hsu BM, Lee KH, Wu PH, Hsu PC. Epigenetic transgenerational effects of prenatal exposure to 2,2',4,4'-tetrabromodiphenyl ether on sperm function and DNA methylation in rat offspring. Food Chem Toxicol. 2025 Nov; 205:115716. PMID: 40889571.
      View in: PubMed
    4. Hsu PI, Yamaoka Y, Chuah SK, Wu DC. Future direction of Helicobacter pylori infection treatment. Lancet. 2025 Jul 19; 406(10500):232. PMID: 40683702.
      View in: PubMed
    5. Hsu PI, Chen CL, Shih CA, Chen KY, Tai WC, Chuah SK, Lee CL, Tsay FW, Yang JC, Lei WY, Kuo CH, Shie CB, Lee HC, Yamaoka Y, Graham DY, Wu DC. Vonoprazan High-Dose Dual, Vonoprazan Triple, and Rabeprazole Reverse Hybrid Therapies for First-Line Treatment of Helicobacter pylori Infection: A Multicenter Randomized Trial. Am J Gastroenterol. 2025 Jun 16. PMID: 40560185.
      View in: PubMed
    6. Cheng FJ, Chuang YP, Pan HY, Hsieh TM, Hsu BM, Hsu PC. Association Between Postacute Sequelae of COVID-19 Infection and Work Environment in a Semiconductor Packaging Plant in Taiwan. J Occup Environ Med. 2025 Sep 01; 67(9):e655-e661. PMID: 40490872.
      View in: PubMed
    7. Singh A, Bakhtyar M, Jun SR, Boerma M, Lan RS, Su LJ, Makhoul S, Hsu PC. A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity. Metabolomics. 2025 May 17; 21(3):68. PMID: 40381141.
      View in: PubMed
    8. Chang ZT, Hsu PC, Ko HW, Chang JW, Wu CT, Huang CY, Chang CF, Kuo CS, Yang CT, Wu CE. Baseline and changes in inflammatory parameters for patients with EGFR-mutated NSCLC treated with afatinib. Thorac Cancer. 2025 Jul; 16(13):e15338. PMID: 40244868.
      View in: PubMed
    9. Kao SS, Wu DC, Chuah SK, Kao JY, Tai WC, Shie CB, Wu IT, Chen WC, Tsay FW, Chen YH, Hsu PI. Comparison of continuous versus on-demand proton pump inhibitor therapy in symptom control of patients with Barrett's esophagus. J Formos Med Assoc. 2025 Mar 10. PMID: 40069015.
      View in: PubMed
    10. Ellis ET, Young SG, Carroll R, Stahr SD, Runnells GA, Grasmuck EA, Su LJ, Park YM, Hsu PC. Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study. Environ Pollut. 2025 Mar 01; 368:125709. PMID: 39828205.
      View in: PubMed
    11. Tsai HJ, Yeh KH, Lin CW, Wu MS, Liou JM, Hsu PN, Zeng YS, Wei MF, Shun CT, Wang HP, Chen LT, Cheng AL, Kuo SH. Cooperative participation of CagA and NFATc1 in the pathogenesis of antibiotics-responsive gastric MALT lymphoma. Cancer Cell Int. 2024 Nov 18; 24(1):383. PMID: 39558403.
      View in: PubMed
    12. Chen CB, Wang CW, Lu CW, Chen WT, Zhou BR, Chu CY, Hsu SF, Yang CT, Wen-Cheng Chang J, Yang CK, Wang CL, Fang YF, Hsu PC, Hua CC, Wu CE, Ko HW, Chen KC, Yang YC, Tseng HC, Cheng AY, Tseng LC, Shih FY, Hung SI, Huang CY, Chung WH. Class I HLA Alleles Are Associated With an Increased Risk of Osimertinib-Induced Hypersensitivity. J Allergy Clin Immunol Pract. 2025 Jan; 13(1):143-154.e10. PMID: 39505105.
      View in: PubMed
    13. Kuo LF, Liu WC, Li MF, Huang FH, Chou CK, Chen TH, Tsai YT, Hsu PI, Li CJ, Wu IT, Tsai KF. Prognostic Evaluation of Conversion Therapy following Hepatic Arterial Infusion Chemotherapy or Immunotherapy in Patients with Advanced or Transarterial Chemoembolization Unsuitable Intermediate-Stage Hepatocellular Carcinoma: A Retrospective Cohort Study. Oncology. 2025; 103(7):549-561. PMID: 39467524.
      View in: PubMed
    14. Hsu PC, Chang JW, Chiu LC, Yang CT, Kuo SC, Fang YF, Wu CE. Analysis of genomic alternations in epidermal growth factor receptor (EGFR)-T790M-mutated non-small cell lung cancer (NSCLC) patients with acquired resistance to osimertinib therapy. Clin Transl Oncol. 2025 May; 27(5):1967-1979. PMID: 39317868.
      View in: PubMed
    15. Leighl NB, Akamatsu H, Lim SM, Cheng Y, Minchom AR, Marmarelis ME, Sanborn RE, Chih-Hsin Yang J, Liu B, John T, Massut? B, Spira AI, Lee SH, Wang J, Li J, Liu C, Novello S, Kondo M, Tamiya M, Korbenfeld E, Moskovitz M, Han JY, Alexander M, Joshi R, Felip E, Voon PJ, Danchaivijitr P, Hsu PC, Silva Melo Cruz FJ, Wehler T, Greillier L, Teixeira E, Nguyen D, Sabari JK, Qin A, Kowalski D, Sendur MAN, Xie J, Ghosh D, Alhadab A, Haddish-Berhane N, Clemens PL, Lorenzini P, Verheijen RB, Gamil M, Bauml JM, Baig M, Passaro A. Subcutaneous Versus Intravenous Amivantamab, Both in Combination With Lazertinib, in Refractory Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer: Primary Results From the Phase III PALOMA-3 Study. J Clin Oncol. 2024 Oct 20; 42(30):3593-3605. PMID: 38857463.
      View in: PubMed
    16. Ellis ET, Fairman BJ, Stahr SD, Bensen JT, Mohler JL, Song L, Butler EN, Su LJ, Hsu PC. Cigarette smoking and prostate cancer aggressiveness among African and European American men. Cancer Causes Control. 2024 Sep; 35(9):1259-1269. PMID: 38758522.
      View in: PubMed
    17. Chyuan IT, Liao HJ, Tan TH, Chuang HC, Chu YC, Pan MH, Wu CS, Chu CL, Sheu BC, Hsu PN. Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck. J Biomed Sci. 2024 Mar 27; 31(1):33. PMID: 38532423.
      View in: PubMed
    18. Chen CL, Wu IT, Wu DC, Lei WY, Tsay FW, Chuah SK, Chen KY, Yang JC, Liu YH, Kuo CH, Shiu SI, Shie CB, Lin KH, Lee CL, Hsu PI. Independent Risk Factors Predicting Eradication Failure of Hybrid Therapy for the First-Line Treatment of Helicobacter pylori Infection. Microorganisms. 2023 Dec 19; 12(1). PMID: 38276175.
      View in: PubMed
    19. Lee CW, Chen KL, Yuan CS, Lai CS, Tsai XY, Wu PH, Hsu PC. Epigenetic transgenerational effects of PM2.5 collected from southern Taiwan on sperm functions and DNA methylation in mouse offspring. Ecotoxicol Environ Saf. 2024 Jan 01; 269:115802. PMID: 38091677.
      View in: PubMed
    20. Su HY, Lai CS, Lee KH, Chiang YW, Chen CC, Hsu PC. Prenatal exposure to low-dose di-(2-ethylhexyl) phthalate (DEHP) induces potentially hepatic lipid accumulation and fibrotic changes in rat offspring. Ecotoxicol Environ Saf. 2024 Jan 01; 269:115776. PMID: 38056127.
      View in: PubMed
    21. Lin CH, Hsu PI, Tseng CD, Chao PJ, Wu IT, Ghose S, Shih CA, Lee SH, Ren JH, Shie CB, Lee TF. Application of artificial intelligence in endoscopic image analysis for the diagnosis of a gastric cancer pathogen-Helicobacter pylori infection. Sci Rep. 2023 08 17; 13(1):13380. PMID: 37592004.
      View in: PubMed
    22. Huang JK, Chuang YS, Wu PH, Tai CJ, Lin JR, Kuo MC, Chiu YW, Hsu PC, Wu MT, Salihovic S, Lin YT. Decreased levels of perfluoroalkyl substances in patients receiving hemodialysis treatment. Sci Total Environ. 2023 Oct 20; 896:165184. PMID: 37391133.
      View in: PubMed
    23. Hsu YC, Chen CH, Huang HF, Lee YT, Wu MC, Su CW, Chou HC, Wang LF, Lee HS, Lin SW, Hsu PN, Wu YM, Sheu JC, Weng MT. Therapeutic Effects of Anti-PD1 Immunotherapy on Hepatocellular Carcinoma Under Administration of Tacrolimus. Transplantation. 2023 07 01; 107(7):1492-1501. PMID: 36380450.
      View in: PubMed
    24. Hsu PI, Chen KY, Tai WC, Yang JC, Tsay FW, Liu YH, Chen CL, Lee CL, Yeh HZ, Kuo CH, Chuah SK, Lee HC, Shie CB, Shiu SI, Kao JY, Yamaoka Y, Graham DY, Wu DC. Hybrid, High-Dose Dual and Bismuth Quadruple Therapies for First-Line Treatment of Helicobacter pylori Infection in Taiwan: A Multicenter, Open-Label, Randomized Trial. Am J Gastroenterol. 2023 07 01; 118(7):1184-1195. PMID: 36940437.
      View in: PubMed
    25. Lu CW, Pang JS, Ko YS, Chang CJ, Wang CW, Chen WT, Chen CB, Hui RC, Hung SI, Lu LY, Lu KL, Wang CL, Wu CE, Hsu PC, Fang YF, Li SH, Ko HW, Tseng LC, Shih FY, Chen MJ, Chung WH. Zinc deficiency associated with cutaneous toxicities induced by epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung adenocarcinoma. J Eur Acad Dermatol Venereol. 2023 Feb; 37(2):328-339. PMID: 36366861.
      View in: PubMed
    26. Chen YH, Jao TM, Shiue YL, Feng IJ, Hsu PI. Prevalence and risk factors for Candida esophagitis among human immunodeficiency virus-negative individuals. World J Clin Cases. 2022 Oct 26; 10(30):10896-10905. PMID: 36338217.
      View in: PubMed
    27. Chuah YY, Wu DC, Chuah SK, Chen KY, Yang JC, Lee CL, Chen CL, Shiu SI, Shie CB, Shih CA, Tsay FW, Liu YH, Hsu PI. REAP-HP survey 2020: Comparing the real-world practice and expectation in Helicobacter pylori eradication of the Taiwanese gastroenterologists in 2015 and 2020. Helicobacter. 2022 Dec; 27(6):e12931. PMID: 36161426.
      View in: PubMed
    28. Pan HY, Cheng FJ, Huang KC, Kung CT, Huang WT, You HL, Li SH, Wang CC, Lee WC, Hsu PC. Exposure to tris(2-butoxyethyl) phosphate induces abnormal sperm morphology and testicular?histopathology in male rats. Ecotoxicol Environ Saf. 2022 Aug; 241:113718. PMID: 35660377.
      View in: PubMed
    29. Yuan CS, Lai CS, Tseng YL, Hsu PC, Lin CM, Cheng FJ. Repeated exposure to fine particulate matter constituents lead to liver inflammation and proliferative response in mice. Ecotoxicol Environ Saf. 2021 11; 224:112636. PMID: 34392150.
      View in: PubMed
    30. Hsu PI, Tsay FW, Kao JY, Peng NJ, Chen YH, Tang SY, Kuo CH, Kao SS, Wang HM, Wu IT, Shie CB, Chuah SK, Wu DC. Tetracycline-levofloxacin versus amoxicillin-levofloxacin quadruple therapies in the second-line treatment of Helicobacter pylori infection. Helicobacter. 2021 Oct; 26(5):e12840. PMID: 34390083.
      View in: PubMed
    31. Wu CE, Chang CF, Huang CY, Yang CT, Kuo CS, Hsu PC, Chang JW. Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study. BMC Cancer. 2021 Jul 27; 21(1):859. PMID: 34315431.
      View in: PubMed
    32. Hsu JC, Nguyen PA, Chen YT, Yang SC, Lin CC, Yang YH, Lin YC, Hsia TC, Hsieh HC, Wu JS, Chang CP, Feng YH, Lin PC, Hsu PC, Tzeng HE, Chien SC, Chang WC, Chang CC, Yang HC, Lee CM, Lu CY. The Effectiveness and Safety of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer Patients With Stage III/IV: A Multicenter Study. Front Oncol. 2021; 11:671127. PMID: 34307141.
      View in: PubMed
    33. Matich EK, Laryea JA, Seely KA, Stahr S, Su LJ, Hsu PC. Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review. Ecotoxicol Environ Saf. 2021 Aug; 219:112327. PMID: 34029839.
      View in: PubMed
    34. Hsu PC, Jhong JY, Huang LP, Lee KH, Chen HP, Guo YL. Transgenerational Effects of Di(2-Ethylhexyl) Phthalate on Anogenital Distance, Sperm Functions and DNA Methylation in Rat Offspring. Int J Mol Sci. 2021 Apr 16; 22(8). PMID: 33923623.
      View in: PubMed
    35. Hsu PC, Li ZK, Lai CS, Tseng LH, Lee CW, Cheng FJ, Chang CY, Chen JR. Transgenerational effects of BDE-209 on male reproduction in F3 offspring rats. Chemosphere. 2021 Jun; 272:129829. PMID: 35534961.
      View in: PubMed
    36. Wu CS, Chyuan IT, Chiu YL, Chen WL, Shen CY, Hsu PN. Preserved specific anti-viral T-cell response but associated with decreased lupus activity in SLE patients with cytomegalovirus infection. Rheumatology (Oxford). 2020 11 01; 59(11):3340-3349. PMID: 32306043.
      View in: PubMed
    37. Lu CW, Wang TY, Yen CF, Chen KH, Wu CE, Wang CL, Hsu PC, Fang YF, Li SH, Ko HW, Tseng LC, Shih FY, Lin YJ, Chen MJ, Chen CB, Su Pang JH, Chung WH, Ko YS. Using betaxolol for the prevention of paronychia induced by epidermal growth factor receptor inhibitors: a case-control cohort study. Int J Dermatol. 2021 Feb; 60(2):179-184. PMID: 32975313.
      View in: PubMed
    38. Chang YL, Tung YC, Tu YK, Yeh HZ, Yang JC, Hsu PI, Kim SE, Wu MF, Liou WS, Shiu SI. Efficacy of second-line regimens for Helicobacter pylori eradication treatment: a systemic review and network meta-analysis. BMJ Open Gastroenterol. 2020 09; 7(1). PMID: 32883715.
      View in: PubMed
    39. Hsu PC, Yang CT, Jablons DM, You L. The Crosstalk between Src and Hippo/YAP Signaling Pathways in Non-Small Cell Lung Cancer (NSCLC). Cancers (Basel). 2020 May 26; 12(6). PMID: 32466572.
      View in: PubMed
    40. Chu CH, Chiu TH, Wang CC, Chang WC, Huang AC, Liu CY, Wang CL, Ko HW, Chung FT, Hsu PC, Guo YK, Kuo CS, Yang CT. Consolidation treatment of durvalumab after chemoradiation in real-world patients with stage III unresectable non-small cell lung cancer. Thorac Cancer. 2020 06; 11(6):1541-1549. PMID: 32281272.
      View in: PubMed
    41. Chyuan IT, Hsu PN. TRAIL regulates T cell activation and suppresses inflammation in autoimmune diseases. Cell Mol Immunol. 2020 12; 17(12):1281-1283. PMID: 32210394.
      View in: PubMed
    42. Tsai TJ, Chen WC, Huang YT, Yang YH, Feng IC, Wu WC, Hu HM, Wu DC, Hsu PI. Hemodialysis Increases the Risk of Lower Gastrointestinal Bleeding and Angiodysplasia Bleeding: A Nationwide Population Study. Gastroenterol Res Pract. 2020; 2020:7206171. PMID: 32190042.
      View in: PubMed
    43. Hsu PI, Chuah SK, Lin JT, Huang SW, Lo JC, Rau KM, Chen IS, Hsu HY, Sheu BS, Chang WK, Wu DC. Taiwan nutritional consensus on the nutrition management for gastric cancer patients receiving gastrectomy. J Formos Med Assoc. 2021 Jan; 120(1 Pt 1):25-33. PMID: 31859187.
      View in: PubMed
    44. Tsai HJ, Tai JJ, Chen LT, Wu MS, Yeh KH, Lin CW, Wang TE, Wang HP, Yu FJ, Liou JM, Hsiao CF, Cheng TY, Yeh HJ, Ko CW, Chen MJ, Lo GH, Hsu PI, Chang CS, Hwang WS, Chuang SS, Lee HW, Shun CT, Chiu CF, Wang WM, Hsieh CY, Liu TW, Lin JT, Kuo SH, Cheng AL. A multicenter prospective study of first-line antibiotic therapy for early-stage gastric mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma with histological evidence of mucosa-associated lymphoid tissue. Haematologica. 2020 07; 105(7):e349-e354. PMID: 31727764.
      View in: PubMed
    45. Huang SH, Huang AC, Wang CC, Chang WC, Liu CY, Pavlidis S, Ko HW, Chung FT, Hsu PC, Guo YK, Kuo CS, Yang CT. Front-line treatment of ceritinib improves efficacy over crizotinib for Asian patients with anaplastic lymphoma kinase fusion NSCLC: The role of systemic progression control. Thorac Cancer. 2019 12; 10(12):2274-2281. PMID: 31613427.
      View in: PubMed
    46. Cheng FJ, Wu KH, Hung SC, Lee KH, Lee CW, Liu KY, Hsu PC. Association between ambient air pollution and out-of-hospital cardiac arrest: are there potentially susceptible groups? J Expo Sci Environ Epidemiol. 2020 07; 30(4):641-649. PMID: 31578416.
      View in: PubMed
    47. Hsu PI, Pan CY, Kao JY, Tsay FW, Peng NJ, Kao SS, Chen YH, Tsai TJ, Wu DC, Tsai KW. Short-term and long-term impacts of Helicobacter pylori eradication with reverse hybrid therapy on the gut microbiota. J Gastroenterol Hepatol. 2019 Nov; 34(11):1968-1976. PMID: 31115933.
      View in: PubMed
    48. Hsu PC, Chang JW, Wang CC, Wu CT, Lin YC, Wang CL, Lin TY, Li SH, Wu YC, Kuo SC, Yang CT, Liu CY, Chen CH. Oral vinorelbine plus cisplatin with concomitant radiotherapy as induction therapy for stage III non-small cell lung cancer: Results of a single-arm prospective cohort study. Thorac Cancer. 2019 08; 10(8):1683-1691. PMID: 31276309.
      View in: PubMed
    49. Kuo SH, Wu MS, Yeh KH, Lin CW, Hsu PN, Chen LT, Cheng AL. Novel Insights of Lymphomagenesis of Helicobacter pylori-Dependent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma. Cancers (Basel). 2019 Apr 17; 11(4). PMID: 30999581.
      View in: PubMed
    50. Cheng HC, Liou JM, Luo JC, Chiu CT, Wu MS, Lee YC, Wu CY, Wu DC, Hsu PI, Chang CC, Chang WL, Lin JT, Sheu BS. The implementation of the consensus on the management of Helicobacter pylori and barriers to consensus. Helicobacter. 2018 Oct; 23(5):e12533. PMID: 30159952.
      View in: PubMed
    51. Hsu PI, Pan CY, Kao JY, Tsay FW, Peng NJ, Kao SS, Wang HM, Tsai TJ, Wu DC, Chen CL, Tsai KW. Helicobacter pylori eradication with bismuth quadruple therapy leads to dysbiosis of gut microbiota with an increased relative abundance of Proteobacteria and decreased relative abundances of Bacteroidetes and Actinobacteria. Helicobacter. 2018 Aug; 23(4):e12498. PMID: 29897654.
      View in: PubMed
    52. Hsu PC, Miao J, Huang Z, Yang YL, Xu Z, You J, Dai Y, Yeh CC, Chan G, Liu S, Urisman A, Yang CT, Jablons DM, You L. Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model. J Cell Mol Med. 2018 06; 22(6):3073-3085. PMID: 29575527.
      View in: PubMed
    53. Hsu PC, Miao J, Wang YC, Zhang WQ, Yang YL, Wang CW, Yang CT, Huang Z, You J, Xu Z, Jablons DM, You L. Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma. J Cell Mol Med. 2018 06; 22(6):3139-3148. PMID: 29575535.
      View in: PubMed
    54. Miao J, Hsu PC, Yang YL, Xu Z, Dai Y, Wang Y, Chan G, Huang Z, Hu B, Li H, Jablons DM, You L. YAP regulates PD-L1 expression in human NSCLC cells. Oncotarget. 2017 Dec 29; 8(70):114576-114587. PMID: 29383103.
      View in: PubMed
    55. Sun WC, Chen IS, Liang HL, Tsai CC, Chen YC, Wang BW, Lin HS, Chan HH, Hsu PI, Tsai WL, Cheng JS. Comparison of repeated surgical resection and radiofrequency ablation for small recurrent hepatocellular carcinoma after primary resection. Oncotarget. 2017 Nov 28; 8(61):104571-104581. PMID: 29262662.
      View in: PubMed
    56. Tsai WL, Chang TH, Sun WC, Chan HH, Wu CC, Hsu PI, Cheng JS, Yu ML. Metformin activates type I interferon signaling against HCV via activation of adenosine monophosphate-activated protein kinase. Oncotarget. 2017 Nov 03; 8(54):91928-91937. PMID: 29190886.
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    57. Lin TF, Hsu PI, Lin KH, Tsay FW, Tsai TJ, Chen YH, Yu HC. Factors Related to Significant Improvement of Estimated Glomerular Filtration Rates in Chronic Hepatitis B Patients Receiving Telbivudine Therapy. Gastroenterol Res Pract. 2017; 2017:4192169. PMID: 28757867.
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    58. Chuah YY, Wu DC, Chuah SK, Yang JC, Lee TH, Yeh HZ, Chen CL, Liu YH, Hsu PI. Real-world practice and Expectation of Asia-Pacific physicians and patients in Helicobacter Pylori eradication (REAP-HP Survey). Helicobacter. 2017 Jun; 22(3). PMID: 28244264.
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    59. Wu CK, Liang CM, Hsu CN, Hung TH, Yuan LT, Nguang SH, Wang JW, Tseng KL, Ku MK, Yang SC, Tai WC, Shih CW, Hsu PI, Wu DC, Chuah SK. The Role of Adjuvant Acid Suppression on the Outcomes of Bleeding Esophageal Varices after Endoscopic Variceal Ligation. PLoS One. 2017; 12(1):e0169884. PMID: 28118373.
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    60. Sheu BS, Wu MS, Chiu CT, Lo JC, Wu DC, Liou JM, Wu CY, Cheng HC, Lee YC, Hsu PI, Chang CC, Chang WL, Lin JT. Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale. Helicobacter. 2017 Jun; 22(3). PMID: 28066960.
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    61. Kuo SH, Chen LT, Lin CW, Yeh KH, Shun CT, Tzeng YS, Liou JM, Wu MS, Hsu PN, Cheng AL. Expressions of the CagA protein and CagA-signaling molecules predict Helicobacter pylori dependence of early-stage gastric DLBCL. Blood. 2017 01 12; 129(2):188-198. PMID: 27864293.
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    62. Wang JW, Hsu CN, Tai WC, Ku MK, Hung TH, Tseng KL, Yuan LT, Nguang SH, Liang CM, Yang SC, Wu CK, Hsu PI, Wu DC, Chuah SK. The Association of Helicobacter pylori Eradication with the Occurrences of Chronic Kidney Diseases in Patients with Peptic Ulcer Diseases. PLoS One. 2016; 11(10):e0164824. PMID: 27764171.
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    63. Hsu PC, Li MC, Lee YC, Kuo PL, Guo YL. Polychlorinated biphenyls and dibenzofurans increased abnormal sperm morphology without alterations in aneuploidy: The Yucheng study. Chemosphere. 2016 Dec; 165:294-297. PMID: 27662390.
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    64. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):51-60. PMID: 27628308.
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    65. Chiang PH, Lai KH, Tsai TJ, Lin KH, Wang KM, Kao SS, Sun WC, Cheng JS, Hsu PI, Tsai WL, Chen WC, Li YD, Wang EM, Lin HS, Chan HH. Is endoscopic treatment beneficial in patients with clinically suspicious of common bile duct stones but no obvious filling defects during the ERCP examination? BMC Gastroenterol. 2016 Aug 26; 16:102. PMID: 27565889.
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    66. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Metabolomic profiles of current cigarette smokers. Mol Carcinog. 2017 02; 56(2):594-606. PMID: 27341184.
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    67. Goh KL, Choi MG, Hsu PI, Chun HJ, Mahachai V, Kachintorn U, Leelakusolvong S, Kim N, Rani AA, Wong BC, Wu J, Chiu CT, Shetty V, Bocobo JC, Chan MM, Lin JT. Pharmacological and Safety Profile of Dexlansoprazole: A New Proton Pump Inhibitor - Implications for Treatment of Gastroesophageal Reflux Disease in the Asia Pacific Region. J Neurogastroenterol Motil. 2016 Jul 30; 22(3):355-66. PMID: 26932927.
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    68. Weng DY, Chen J, Taslim C, Hsu PC, Marian C, David SP, Loffredo CA, Shields PG. Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog. 2016 10; 55(10):1424-37. PMID: 26294040.
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    69. Hsu PI, Yamaoka Y, Goh KL, Manfredi M, Wu DC, Mahachai V. Helicobacter pylori Infection. Biomed Res Int. 2015; 2015:278308. PMID: 26078943.
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    70. Kao JT, Feng CL, Yu CJ, Tsai SM, Hsu PN, Chen YL, Wu YY. IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study. BMC Gastroenterol. 2015 Apr 25; 15:50. PMID: 25908103.
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    71. Sun WC, Chan HH, Lai KH, Tsai TJ, Lin HS, Lin KH, Wang KM, Kao SS, Chiang PH, Cheng JS, Hsu PI, Tsai WL, Chen WC, Li YD, Wang EM. The efficacy of endoscopic papillary balloon dilation for patients with acute biliary pancreatitis. Gastroenterol Res Pract. 2015; 2015:575898. PMID: 25949236.
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    72. Hsu WH, Kuo FC, Hu HM, Hsu PI, Wu DC, Kuo CH. Genetic polymorphisms of CYP2C19 and IL1B have no influence on esomeprazole treatment for mild erosive esophagitis. Kaohsiung J Med Sci. 2015 May; 31(5):255-9. PMID: 25910560.
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    73. Hsu PI, Lu CL, Wu DC, Kuo CH, Kao SS, Chang CC, Tai WC, Lai KH, Chen WC, Wang HM, Cheng JS, Tsai TJ, Chuah SK. Eight weeks of esomeprazole therapy reduces symptom relapse, compared with 4 weeks, in patients with Los Angeles grade A or B erosive esophagitis. Clin Gastroenterol Hepatol. 2015 May; 13(5):859-66.e1. PMID: 25245625.
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    74. Sheu BS, Wu CY, Wu MS, Chiu CT, Lin CC, Hsu PI, Cheng HC, Lee TY, Wang HP, Lin JT. Consensus on control of risky nonvariceal upper gastrointestinal bleeding in Taiwan with National Health Insurance. Biomed Res Int. 2014; 2014:563707. PMID: 25197649.
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    75. Hsu PI, Wu DC, Chen WC, Tseng HH, Yu HC, Wang HM, Kao SS, Lai KH, Chen A, Tsay FW. Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. Antimicrob Agents Chemother. 2014 Oct; 58(10):5936-42. PMID: 25070099.
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    76. Lee KH, Chen HL, Leung CM, Chen HP, Hsu PC. Indium acetate toxicity in male reproductive system in rats. Environ Toxicol. 2016 Jan; 31(1):68-76. PMID: 25044390.
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    77. Liu PF, Leung CM, Chang YH, Cheng JS, Chen JJ, Weng CJ, Tsai KW, Hsu CJ, Liu YC, Hsu PC, Pan HW, Shu CW. ATG4B promotes colorectal cancer growth independent of autophagic flux. Autophagy. 2014 Aug; 10(8):1454-65. PMID: 24991826.
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    78. Tsai WL, Lai KH, Liang HL, Hsu PI, Chan HH, Chen WC, Yu HC, Tsay FW, Wang HM, Tsai HC, Cheng JS. Hepatic arterial infusion chemotherapy for patients with huge unresectable hepatocellular carcinoma. PLoS One. 2014; 9(5):e92784. PMID: 24824520.
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    79. Chu TH, Chan HH, Kuo HM, Liu LF, Hu TH, Sun CK, Kung ML, Lin SW, Wang EM, Ma YL, Cheng KH, Lai KH, Wen ZH, Hsu PI, Tai MH. Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. Oncotarget. 2014 Mar 30; 5(6):1475-90. PMID: 24721996.
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    80. Leung CM, Chen TW, Li SC, Ho MR, Hu LY, Liu WS, Wu TT, Hsu PC, Chang HT, Tsai KW. MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. Oncol Rep. 2014 May; 31(5):2147-56. PMID: 24626680.
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    81. Leung CM, Li SC, Chen TW, Ho MR, Hu LY, Liu WS, Wu TT, Hsu PC, Chang HT, Tsai KW. Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. Oncol Rep. 2014 Mar; 31(3):1067-78. PMID: 24452514.
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    82. Wang HM, Chan HH, Wu MJ, Hsu PI, Lin CK, Yu HC, Chen WC, Tsai WL, Tsay FW, Tsai TJ. Not only hysterectomy but also cesarean section can predict incomplete flexible sigmoidoscopy among patients with prior abdominal or pelvic surgery. J Chin Med Assoc. 2014 Mar; 77(3):122-7. PMID: 24388006.
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    83. Huang YW, Lin SC, Wei SC, Hu JT, Chang HY, Huang SH, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy. Antivir Ther. 2013; 18(7):877-84. PMID: 23744559.
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    84. Hsu PC, Zhou B, Zhao Y, Ressom HW, Cheema AK, Pickworth W, Shields PG. Feasibility of identifying the tobacco-related global metabolome in blood by UPLC-QTOF-MS. J Proteome Res. 2013 Feb 01; 12(2):679-91. PMID: 23240883.
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    85. Kuo CH, Hsu PI, Kuo FC, Wang SS, Hu HM, Liu CJ, Chuah SK, Chen YH, Hsieh MC, Wu DC, Tseng HH. Comparison of 10 day bismuth quadruple therapy with high-dose metronidazole or levofloxacin for second-line Helicobacter pylori therapy: a randomized controlled trial. J Antimicrob Chemother. 2013 Jan; 68(1):222-8. PMID: 22984204.
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    86. Wang HM, Lo GH, Chen WC, Hsu PI, Yu HC, Lin CK, Chan HH, Tsai WL, Tsay FW, Liu TP, Wang EM, Lai KH. Efficacy of transient elastography in screening for large esophageal varices in patients with suspicious or proven liver cirrhosis. J Dig Dis. 2012 Aug; 13(8):430-8. PMID: 22788929.
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    87. Lin YS, Caffrey JL, Hsu PC, Chang MH, Faramawi MF, Lin JW. Environmental exposure to dioxin-like compounds and the mortality risk in the U.S. population. Int J Hyg Environ Health. 2012 Nov; 215(6):541-6. PMID: 22429684.
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    88. Lin KH, Hsu PI, Yu HC, Lin CK, Tsai WL, Chen WC, Chan HH, Lai KH. Factors linked to severe thrombocytopenia during antiviral therapy in patients with chronic hepatitis c and pretreatment low platelet counts. BMC Gastroenterol. 2012 Jan 18; 12:7. PMID: 22257364.
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    89. Kao JT, Lai HC, Tsai SM, Lin PC, Chuang PH, Yu CJ, Cheng KS, Su WP, Hsu PN, Peng CY, Wu YY. Rather than interleukin-27, interleukin-6 expresses positive correlation with liver severity in na?ve hepatitis B infection patients. Liver Int. 2012 Jul; 32(6):928-36. PMID: 22230324.
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    90. Hung LJ, Hsu PI, Yang CY, Wang EM, Lai KH. Prevalence of gastroesophageal reflux disease in a general population in Taiwan. J Gastroenterol Hepatol. 2011 Jul; 26(7):1164-8. PMID: 21517967.
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    91. Wu DC, Hsu PI, Tseng HH, Tsay FW, Lai KH, Kuo CH, Wang SW, Chen A. Helicobacter pylori infection: a randomized, controlled study comparing 2 rescue therapies after failure of standard triple therapies. Medicine (Baltimore). 2011 May; 90(3):180-185. PMID: 21512411.
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    92. Wang FW, Tu MS, Mar GY, Chuang HY, Yu HC, Cheng LC, Hsu PI. Prevalence and risk factors of asymptomatic peptic ulcer disease in Taiwan. World J Gastroenterol. 2011 Mar 07; 17(9):1199-203. PMID: 21448426.
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    93. Hsu PI, Chen CH, Hsiao M, Wu DC, Lin CY, Lai KH, Lu PJ. Diagnosis of gastric malignancy using gastric juice alpha1-antitrypsin. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):405-11. PMID: 20086110.
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    94. Wang FW, Tu MS, Chuang HY, Yu HC, Cheng LC, Hsu PI. Erosive esophagitis in asymptomatic subjects: risk factors. Dig Dis Sci. 2010 May; 55(5):1320-4. PMID: 19685186.
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    95. Tsai TJ, Lai KH, Hsu PI, Tsai CC, Fu TY. Gallbladder cancer manifesting as recurrent common bile duct stone and duodenal ulcer bleeding. J Chin Med Assoc. 2009 Aug; 72(8):434-7. PMID: 19687000.
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    96. Chuah SK, Hu TH, Wu KL, Hsu PI, Tai WC, Chiu YC, Lee CM, Changchien CS. Clinical remission in endoscope-guided pneumatic dilation for the treatment of esophageal achalasia: 7-year follow-up results of a prospective investigation. J Gastrointest Surg. 2009 May; 13(5):862-7. PMID: 19165550.
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    97. Chan HH, Lai KH, Lin CK, Tsai WL, Peng NJ, Hsu PI, Lo GH, Wei MC, Wang EM, Chang HW. Impact of food on hepatic clearance of patients after endoscopic sphincterotomy. J Chin Med Assoc. 2009 Jan; 72(1):10-4. PMID: 19181591.
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    98. Chen TA, Tsao YC, Chen A, Lo GH, Lin CK, Yu HC, Cheng LC, Hsu PI, Tsai WL. Effect of intravenous albumin on endotoxin removal, cytokines, and nitric oxide production in patients with cirrhosis and spontaneous bacterial peritonitis. Scand J Gastroenterol. 2009; 44(5):619-25. PMID: 19191184.
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    99. Chan HH, Lai KH, Lin CK, Tsai WL, Lo GH, Hsu PI, Wei MC, Wang EM. Effect of somatostatin in the prevention of pancreatic complications after endoscopic retrograde cholangiopancreatography. J Chin Med Assoc. 2008 Dec; 71(12):605-9. PMID: 19114324.
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    100. Lo GH, Chen WC, Lin CK, Tsai WL, Chan HH, Chen TA, Yu HC, Hsu PI, Lai KH. Improved survival in patients receiving medical therapy as compared with banding ligation for the prevention of esophageal variceal rebleeding. Hepatology. 2008 Aug; 48(2):580-7. PMID: 18666235.
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    101. Kuo SH, Yeh PY, Chen LT, Wu MS, Lin CW, Yeh KH, Tzeng YS, Chen JY, Hsu PN, Lin JT, Cheng AL. Overexpression of B cell-activating factor of TNF family (BAFF) is associated with Helicobacter pylori-independent growth of gastric diffuse large B-cell lymphoma with histologic evidence of MALT lymphoma. Blood. 2008 Oct 01; 112(7):2927-34. PMID: 18628489.
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    102. Hsu PI, Jwo JJ, Yang CL, Hsu PN, Yang HB, Lai KH, Chen IS, Chuah SK, Wu DC, Chen A. Association of the myeloperoxidase polymorphism with the risk of gastric cancer. Anticancer Res. 2008 Mar-Apr; 28(2B):1317-23. PMID: 18505072.
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    103. Yu HC, Lo GH, Lai KH, Hsu PI, Chen IS, Hsieh PP. Adenomyoma of the jejunum --- a rare cause of gastrointestinal bleeding. J Chin Med Assoc. 2008 Feb; 71(2):96-9. PMID: 18290255.
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    104. Chou MY, Hsu PI, Chou SL, Chou YM, Wang FW, Hsueh KC, Chen LK, Hwang SJ, Tu MS. Factors related to incomplete flexible sigmoidoscopy among adult Chinese in Taiwan. J Chin Med Assoc. 2007 Sep; 70(9):361-6. PMID: 17908649.
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    105. Chen TA, Lo GH, Lin CK, Lai KH, Wong HY, Yu HC, Hsu PI, Chen HH, Tsai WL, Chen WC. Acute pancreatitis-associated acute gastrointestinal mucosal lesions: incidence, characteristics, and clinical significance. J Clin Gastroenterol. 2007 Jul; 41(6):630-4. PMID: 17577121.
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    106. Hsu PC, Pan MH, Li LA, Chen CJ, Tsai SS, Guo YL. Exposure in utero to 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring. Toxicol Appl Pharmacol. 2007 May 15; 221(1):68-75. PMID: 17445852.
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    107. Lin TC, Chien SC, Hsu PC, Li LA. Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation. Endocrinology. 2006 Mar; 147(3):1536-44. PMID: 16396990.
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    108. Hsu PI, Lai KH, Lin CK, Chen WC, Yu HC, Cheng JS, Tsay FW, Wu CJ, Lo CC, Tseng HH, Yamaoka Y, Chen JL, Lo GH. A prospective randomized trial of esomeprazole- versus pantoprazole-based triple therapy for Helicobacter pylori eradication. Am J Gastroenterol. 2005 Nov; 100(11):2387-92. PMID: 16279889.
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    109. Lo GH, Yu HC, Chan YC, Chen WC, Hsu PI, Lin CK, Lai KH. The effects of eradication of Helicobacter pylori on the recurrence of duodenal ulcers in patients with cirrhosis. Gastrointest Endosc. 2005 Sep; 62(3):350-6. PMID: 16111950.
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    110. Hung CH, Li CY, Lai YS, Hsu PC, Hua YM, Yang KD. Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma. Pediatr Allergy Immunol. 2005 Jun; 16(4):306-9. PMID: 15943593.
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    111. Hsu PI, Jwo JJ, Tseng HH, Lai KH, Lo GH, Lo CC, Wu CJ, Chuah SK, Hwang IR, Chen JL, Chen YS, Chen A. Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk. World J Gastroenterol. 2005 May 14; 11(18):2796-801. PMID: 15884126.
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    112. Lu H, Hsu PI, Graham DY, Yamaoka Y. Duodenal ulcer promoting gene of Helicobacter pylori. Gastroenterology. 2005 Apr; 128(4):833-48. PMID: 15825067.
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    113. Hsu PI, Li CN, Tseng HH, Lai KH, Hsu PN, Lo GH, Lo CC, Yeh JJ, Ger LP, Hsiao M, Yamaoka Y, Hwang IR, Chen A. The interleukin-1 RN polymorphism and Helicobacter pylori infection in the development of duodenal ulcer. Helicobacter. 2004 Dec; 9(6):605-13. PMID: 15610073.
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    114. Chen WC, Lo GH, Lai KH, Cheng JS, Hsu PI, Lin CK. Development of hepatocellular carcinoma after successful management of esophageal variceal bleeding. J Chin Med Assoc. 2004 Nov; 67(11):557-64. PMID: 15720069.
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    115. Tsai CS, Hsu PC, Huang GS, Lin TC, Hong GJ, Shih CM, Li CY. Midazolam attenuates adenosine diphosphate-induced P-selectin expression and platelet-leucocyte aggregation. Eur J Anaesthesiol. 2004 Nov; 21(11):871-6. PMID: 15717703.
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    116. Lo GH, Chen WC, Chen MH, Tsai WL, Chan HH, Cheng LC, Hsu PI, Lai KH. The characteristics and the prognosis for patients presenting with actively bleeding esophageal varices at endoscopy. Gastrointest Endosc. 2004 Nov; 60(5):714-20. PMID: 15557947.
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    117. Hsu PC, Huang YT, Tsai ML, Wang YJ, Lin JK, Pan MH. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. J Agric Food Chem. 2004 Oct 06; 52(20):6330-7. PMID: 15453709.
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    118. Huang GS, Li CY, Hsu PC, Tsai CS, Lin TC, Wong CS. Sevoflurane anesthesia attenuates adenosine diphosphate-induced P-selectin expression and platelet-leukocyte conjugate formation. Anesth Analg. 2004 Oct; 99(4):1121-1126. PMID: 15385361.
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    119. Wu YY, Tsai HF, Lin WC, Chou AH, Chen HT, Yang JC, Hsu PI, Hsu PN. Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells. World J Gastroenterol. 2004 Aug 15; 10(16):2334-9. PMID: 15285015.
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    120. Chang HY, Shih TS, Guo YL, Tsai CY, Hsu PC. Sperm function in workers exposed to N,N-dimethylformamide in the synthetic leather industry. Fertil Steril. 2004 Jun; 81(6):1589-94. PMID: 15193482.
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    121. Wu CJ, Hsu PI, Lo GH, Lo CC, Lin CK, Shie CB, Peng NJ, Tseng HH, Jou HS, Tsai PM, Chen A, Chen JL, Lai KH. Comparison of cetraxate-based and pantoprazole-based triple therapies in the treatment of Helicobacter pylori infection. J Chin Med Assoc. 2004 Apr; 67(4):161-7. PMID: 15244013.
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    122. Lo GH, Chen WC, Chen MH, Lin CP, Lo CC, Hsu PI, Cheng JS, Lai KH. Endoscopic ligation vs. nadolol in the prevention of first variceal bleeding in patients with cirrhosis. Gastrointest Endosc. 2004 Mar; 59(3):333-8. PMID: 14997127.
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    123. Tsai HF, Lai JJ, Chou AH, Wang TF, Wu CS, Hsu PN. Induction of costimulation of human CD4 T cells by tumor necrosis factor-related apoptosis-inducing ligand: possible role in T cell activation in systemic lupus erythematosus. Arthritis Rheum. 2004 Feb; 50(2):629-39. PMID: 14872508.
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    124. Li CY, Tsai CS, Hsu PC, Chueh SH, Wong CS, Ho ST. Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: possible mechanisms for its effect on inflammation. Anesth Analg. 2003 Nov; 97(5):1312-1316. PMID: 14570645.
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    125. Li CY, Tsai CS, Hsu PC, Wu CT, Wong CS, Ho ST. Dobutamine modulates lipopolysaccharide-induced macrophage inflammatory protein-1alpha and interleukin-8 production in human monocytes. Anesth Analg. 2003 Jul; 97(1):210-5, table of contents. PMID: 12818968.
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    126. Li CY, Tsai CS, Chueh SH, Hsu PC, Wang JY, Wong CS, Ho ST. Dobutamine inhibits monocyte chemoattractant protein-1 production and chemotaxis in human monocytes. Anesth Analg. 2003 Jul; 97(1):205-9, table of contents. PMID: 12818967.
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    127. Yeh GC, Chen JC, Tsai HC, Wu HH, Lin CY, Hsu PC, Peng YC. Amphetamine inhibits the N-methyl-D-aspartate receptor-mediated responses by directly interacting with the receptor/channel complex. J Pharmacol Exp Ther. 2002 Mar; 300(3):1008-16. PMID: 11861810.
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    128. Chen JY, Hsu PC, Hsu IL, Yeh GC. Sequential up-regulation of the c-fos, c-jun and bax genes in the cortex, striatum and cerebellum induced by a single injection of a low dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6 mice. Neurosci Lett. 2001 Nov 13; 314(1-2):49-52. PMID: 11698144.
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