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Fen Xia

TitleDepartment Chairperson
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentRadiation Oncology, College of Medicine
Address4130 Shuffield Dr.
Mail Slot # 771
Little Rock AR 72205
Phone501-686-7283
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    Collapse Research 
    Collapse research activities and funding
    R01CA247947     (XIA, FEN)Apr 1, 2020 - Mar 31, 2026
    NIH
    The novel role of Sirtuin 2 in regulation of transcription-associated DNA damage repair
    Role: Principal Investigator

    P20GM125503     (O'BRIEN, CHARLES A)Feb 16, 2018 - Jan 31, 2023
    NIH
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Co-Investigator

    R01CA188500     (XIA, FEN)Sep 2, 2014 - Aug 31, 2021
    NIH
    Novel functions of Pyruvate kinase M2 in DNA double-strand break repair
    Role: Principal Investigator

    R01CA188500     (XIA, FEN)Sep 2, 2014 - Aug 31, 2020
    NIH/NCI
    Novel functions of Pyruvate kinase M2 in DNA double-strand break repair
    Role: Principal Investigator

    R01CA163838     (XIA, FEN)Jul 12, 2012 - Apr 30, 2019
    NIH
    GSK3b mediates radiation-induced cytotoxicity in hippocampal neurons
    Role: Principal Investigator

    R01CA163838     (XIA, FEN)Jul 12, 2012 - Apr 30, 2017
    NIH/NCI
    GSK3b mediates radiation-induced cytotoxicity in hippocampal neurons
    Role: Principal Investigator

    R01CA118158     (XIA, FEN)Sep 26, 2006 - Oct 31, 2012
    NIH
    The role of BRCA1 in nonhomologous repair of chromosomal double-strand breaks
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Kiss RC, Xia F, Acklin S. Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment. Int J Mol Sci. 2021 Jul 30; 22(15). PMID: 34360968.
      View in: PubMed
    2. Zhang M, Acklin S, Gillenwater J, Du W, Patra M, Yu H, Xu B, Yu J, Xia F. SIRT2 promotes murine melanoma progression through natural killer cell inhibition. Sci Rep. 2021 06 21; 11(1):12988. PMID: 34155309.
      View in: PubMed
    3. Prabhu AV, Lee M, Galhardo E, Newkirk M, Rodriguez A, Xia F. Pulsed reduced dose-rate radiotherapy for previously irradiated tumors in the brain and spine. Surg Neurol Int. 2021; 12:280. PMID: 34221611.
      View in: PubMed
    4. Acklin S, Xia F. The Role of Nucleotide Excision Repair in Cisplatin-Induced Peripheral Neuropathy: Mechanism, Prevention, and Treatment. Int J Mol Sci. 2021 Feb 17; 22(4). PMID: 33671279.
      View in: PubMed
    5. Acklin S, Zhang M, Du W, Zhao X, Plotkin M, Chang J, Campisi J, Zhou D, Xia F. Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice. Sci Rep. 2020 08 25; 10(1):14170. PMID: 32843706.
      View in: PubMed
    6. Patel M, Nowsheen S, Maraboyina S, Xia F. The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review. Cell Biosci. 2020; 10:35. PMID: 32180937.
      View in: PubMed
    7. Zhao X, Du W, Zhang M, Atiq ZO, Xia F. Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury. BMC Genomics. 2020 Mar 02; 21(1):192. PMID: 32122297.
      View in: PubMed
    8. Miousse IR, Tobacyk J, Quick CM, Jamshidi-Parsian A, Skinner CM, Kore R, Melnyk SB, Kutanzi KR, Xia F, Griffin RJ, Koturbash I. Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors. Carcinogenesis. 2018 09 21; 39(9):1117-1126. PMID: 29939201.
      View in: PubMed
    9. Yu H, Harrison FE, Xia F. Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity. Sci Rep. 2018 04 04; 8(1):5600. PMID: 29618789.
      View in: PubMed
    10. Zhang X, Rong Y, Morrill S, Fang J, Narayanasamy G, Galhardo E, Maraboyina S, Croft C, Xia F, Penagaricano J. Robust optimization in lung treatment plans accounting for geometric uncertainty. J Appl Clin Med Phys. 2018 May; 19(3):19-26. PMID: 29524301.
      View in: PubMed
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