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William Mustain

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentSurgery, College of Medicine
DivisionSurgery Colorectal
Address324 UAMS Campus Dr.
Mail Slot # 520
Little Rock AR 72205
Phone501-686-6757
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    Collapse Overview 
    Collapse overview
    Dr. W. Conan Mustain is a native of Jackson, MS. He attended Florida State University, where he was inducted into the Phi Beta Kappa society and graduated Magna Cum Laude. After earning his medical degree at the University of Mississippi School of Medicine, Dr. Mustain completed his internship and residency in general surgery at the University of Kentucky Medical Center in Lexington, where he served as Administrative Chief Resident. During residency he spent 2 years as a surgical research fellow in the University of Kentucky Markey Cancer Center conducting basic science research in colorectal cancer and inflammatory bowel disease. After residency he completed fellowship training in colon and rectal surgery at University Hospitals Case Medical Center-Case Western Reserve University in Cleveland, OH. Dr. Mustain is an assistant professor in the Department of Surgery. Dr. Mustain is board-certified in general surgery and board-eligible in colon and rectal surgery. He specializes in the treatment of diseases of the colon and rectum including colorectal cancer, inflammatory bowel disease, diverticulitis, fecal incontinence, rectal prolapse, and benign anorectal conditions. His special interests include laparoscopic colon and rectal surgery, complex anorectal disease, and sphincter-preserving surgery for rectal cancer. He is a member of the American Society of Colon and Rectal Surgeons, the American College of Surgeons, and the Alpha Omega Alpha Honor Medical Society. He has won numerous awards for excellence in teaching and research and has presented his work at several national and regional meetings. Dr. Mustain lives in the Hillcrest neighborhood in Little Rock with his wife and two young boys. He sees patients in the Winthrop P. Rockefeller Cancer Institute


    Collapse Research 
    Collapse research activities and funding
    228721; Prime Contract #585918     (MUSTAIN, WILLIAM)Feb 15, 2019
    Crohn's and Colitis Foundation of America - Pass Through: Cedars Sinai Medical Center
    The United States Ileal Pouch- Anal Anastomosis Study (TULIP)(IRB 228721)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Huang J, Tang X, Xu Y, Zhang C, Chen T, Yu Y, Mustain W, Allison J, Iversen MM, Rabbitt RD, Zhou W, Zhu H. Correction to: Differential Activation of Canal and Otolith Afferents by Acoustic Tone Bursts in Rats. J Assoc Res Otolaryngol. 2022 Jun; 23(3):455. PMID: 35460013.
      View in: PubMed
    2. Huang J, Tang X, Xu Y, Zhang C, Chen T, Yu Y, Mustain W, Allison J, Iversen MM, Rabbitt RD, Zhou W, Zhu H. Differential Activation of Canal and Otolith Afferents by Acoustic Tone Bursts in Rats. J Assoc Res Otolaryngol. 2022 06; 23(3):435-453. PMID: 35378621.
      View in: PubMed
    3. Chen T, Huang J, Yu Y, Tang X, Zhang C, Xu Y, Arteaga A, Allison J, Mustain W, Donald MC, Rappai T, Zhang M, Zhou W, Zhu H. Sound-Evoked Responses in the Vestibulo-Ocular Reflex Pathways of Rats. Front Neurosci. 2021; 15:741571. PMID: 34720863.
      View in: PubMed
    4. Stoner K, Preston MA, Mustain WC, Mizell JS, Mehaffey G, Laryea JA. The Impact of Transversus Abdominis Plane Block Within an Enhanced Recovery After Surgery Protocol on Length of Stay. Dis Colon Rectum. 2021 03 01; 64(3):313-318. PMID: 33395140.
      View in: PubMed
    5. Yu Y, Huang J, Tang X, Allison J, Sandlin D, Ding D, Pang Y, Zhang C, Chen T, Yin N, Chen L, Mustain W, Zhou W, Zhu H. Exposure to blast shock waves via the ear canal induces deficits in vestibular afferent function in rats. J Otol. 2020 Sep; 15(3):77-85. PMID: 32884557.
      View in: PubMed
    6. Prieto SP, Lai KK, Laryea JA, Mizell JS, Mustain WC, Muldoon TJ. Fluorescein as a topical fluorescent contrast agent for quantitative microendoscopic inspection of colorectal epithelium. Biomed Opt Express. 2017 Apr 01; 8(4):2324-2338. PMID: 28736674.
      View in: PubMed
    7. Ashford A, Huang J, Zhang C, Wei W, Mustain W, Eby T, Zhu H, Zhou W. The Cervical Vestibular-Evoked Myogenic Potentials (cVEMPs) Recorded Along the Sternocleidomastoid Muscles During Head Rotation and Flexion in Normal Human Subjects. J Assoc Res Otolaryngol. 2016 Aug; 17(4):303-11. PMID: 27105980.
      View in: PubMed
    8. Stewart C, Yu Y, Huang J, Maklad A, Tang X, Allison J, Mustain W, Zhou W, Zhu H. Effects of high intensity noise on the vestibular system in rats. Hear Res. 2016 05; 335:118-127. PMID: 26970474.
      View in: PubMed
    9. Rychahou P, Haque F, Shu Y, Zaytseva Y, Weiss HL, Lee EY, Mustain W, Valentino J, Guo P, Evers BM. Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration. ACS Nano. 2015 Feb 24; 9(2):1108-16. PMID: 25652125.
      View in: PubMed
    10. Zaytseva YY, Elliott VA, Rychahou P, Mustain WC, Kim JT, Valentino J, Gao T, O'Connor KL, Neltner JM, Lee EY, Weiss HL, Evers BM. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer. Carcinogenesis. 2014 Jun; 35(6):1341-51. PMID: 24510238.
      View in: PubMed
    11. Valentino JD, Li J, Zaytseva YY, Mustain WC, Elliott VA, Kim JT, Harris JW, Campbell K, Weiss H, Wang C, Song J, Anthony L, Townsend CM, Evers BM. Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors. Clin Cancer Res. 2014 Mar 01; 20(5):1212-22. PMID: 24443523.
      View in: PubMed
    12. Mustain WC, Starr ME, Valentino JD, Cohen DA, Okamura D, Wang C, Evers BM, Saito H. Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitis. PLoS One. 2013; 8(12):e83693. PMID: 24386254.
      View in: PubMed
    13. Zhu H, Tang X, Wei W, Maklad A, Mustain W, Rabbitt R, Highstein S, Allison J, Zhou W. Input-output functions of vestibular afferent responses to air-conducted clicks in rats. J Assoc Res Otolaryngol. 2014 Feb; 15(1):73-86. PMID: 24297262.
      View in: PubMed
    14. Valentino JD, Rychahou PG, Mustain WC, Elliott VA, Evers BM. Murine portal vein catheterization to analyze liver-directed therapies. J Surg Res. 2013 Dec; 185(2):690-6. PMID: 23890402.
      View in: PubMed
    15. Wei W, Jeffcoat B, Mustain W, Zhu H, Eby T, Zhou W. Frequency tuning of the cervical vestibular-evoked myogenic potential (cVEMP) recorded from multiple sites along the sternocleidomastoid muscle in normal human subjects. J Assoc Res Otolaryngol. 2013 Feb; 14(1):37-47. PMID: 23183876.
      View in: PubMed
    16. Valentino JD, Elliott VA, Zaytseva YY, Rychahou PG, Mustain WC, Wang C, Gao T, Evers BM. Novel small interfering RNA cotargeting strategy as treatment for colorectal cancer. Surgery. 2012 Aug; 152(2):277-85. PMID: 22828149.
      View in: PubMed
    17. Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY, Evers BM. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012 Mar 15; 72(6):1504-17. PMID: 22266115.
      View in: PubMed
    18. Zhu H, Tang X, Wei W, Mustain W, Xu Y, Zhou W. Click-evoked responses in vestibular afferents in rats. J Neurophysiol. 2011 Aug; 106(2):754-63. PMID: 21613592.
      View in: PubMed
    19. Mustain WC, Rychahou PG, Evers BM. The role of neurotensin in physiologic and pathologic processes. Curr Opin Endocrinol Diabetes Obes. 2011 Feb; 18(1):75-82. PMID: 21124211.
      View in: PubMed
    20. Donnellan K, Wei W, Jeffcoat B, Mustain W, Xu Y, Eby T, Zhou W. Frequency tuning of bone-conducted tone burst-evoked myogenic potentials recorded from extraocular muscles (BOVEMP) in normal human subjects. Laryngoscope. 2010 12; 120(12):2555-60. PMID: 21108434.
      View in: PubMed
    21. Lewis A, Mustain W, Xu Y, Eby T, Zhou W. Frequency tuning in the tone burst-evoked myogenic potentials in extraocular muscles in normal human subjects. J Otolaryngol Head Neck Surg. 2010 Oct; 39(5):491-7. PMID: 20828510.
      View in: PubMed
    22. Tang X, Xu Y, Simpson I, Jeffcoat B, Mustain W, Zhou W. The conjugacy of the vestibulo-ocular reflex evoked by single labyrinth stimulation in awake monkeys. Exp Brain Res. 2010 Oct; 206(3):249-55. PMID: 20820761.
      View in: PubMed
    23. Jeffcoat B, Shelukhin A, Fong A, Mustain W, Zhou W. Alexander's Law revisited. J Neurophysiol. 2008 Jul; 100(1):154-9. PMID: 18450584.
      View in: PubMed
    24. Chen WJ, Zhang F, Mustain WC, Tucci M, Hu EC, Lineaweaver WC. Prefabrication of vascularized bone flap by demineralized bone matrix. J Craniofac Surg. 2007 Jan; 18(1):43-8. PMID: 17251834.
      View in: PubMed
    25. Song C, Zhang F, Zhang J, Mustain WC, Chen MB, Chen T, Lineaweaver WC. Neuroma-in-continuity model in rabbits. Ann Plast Surg. 2006 Sep; 57(3):317-22. PMID: 16929202.
      View in: PubMed
    26. Zhang F, Brooks D, Chen W, Mustain W, Chen MB, Lineaweaver WC. Improvement of venous flap survival by application of vascular endothelial growth factor in a rat model. Ann Plast Surg. 2006 Jun; 56(6):670-3. PMID: 16721083.
      View in: PubMed
    27. Lineaweaver WC, Lei MP, Mustain W, Oswald TM, Cui D, Zhang F. Vascular endothelium growth factor, surgical delay, and skin flap survival. Ann Surg. 2004 Jun; 239(6):866-73; discussion 873-5. PMID: 15166966.
      View in: PubMed
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