Lawrence Cornett
Title | Distinguished Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Physiology & Cell Biology, College of Medicine |
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Division | Physiology & Cell Biology Faculty |
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Address | 159-2 Biomedical Research II 200 South Cedar Mail Slot # 505 Little Rock AR 72202
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Phone | 501-686-5441 |
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vCard | Download vCard |
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Title | Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Internal Medicine, College of Medicine |
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Division | Pulmonary & Critical Care |
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Overview Dr. Cornett is a professor in the Department of Physiology and Cell Biology at the University of Arkansas for Medical Sciences. Dr. Cornett earned a BS in biology from the University of California, Riverside, his PhD in physiology from the University of California, Davis and was a postdoctoral fellow in reproductive endocrinology and cardiovascular physiology at the University of California, San Francisco. His research interest include the role of beta2-adrenergic receptors in mediating airway responsiveness in asthma and hormonal regulation of stress responses at the level of the pituitary gland. In addition, Dr. Cornett is the Director of the Arkansas IDeA Network of Biomedical Research Excellence (INBRE), a program funded by the National Institutes of Health to develop biomedical research infrastructure in the state. Dr. Cornett is a member of the EPSCoR/IDeA Foundation Board, the Arkansas Children's Research Institute Board, and a member of the National Committee for the National Association of IDeA Principal Investigators. Among his many honors, Dr. Cornett received a fellowship from the NIH Fogarty Center and a Research Career Enhancement Award from the American Physiological Society.
Affiliation Endocrine Society American Physiological Society
Biography Research 3P20GM103429 (CORNETT, LAWRENCE E)May 1, 2020 - Apr 30, 2025 NIH/Nat. Inst. of General Medical Sciences - Pass Through: NIH/Nat. Inst. of General Medical Sciences Partnerships for Biomedical Research in Arkansas - Admin Supplement Role: Principal Investigator |
| 3P20GM103429-21S3 (CORNETT, LAWRENCE E)May 1, 2020 - Apr 30, 2025 NIH/Nat. Inst. of General Medical Sciences Partnerships for Biomedical Research in Arkansas - Admin Supplement Role: Principal Investigator |
| P20 GM103429 (CORNETT, LAWRENCE E)May 1, 2020 - Apr 30, 2025 NIH/Nat. Inst. of General Medical Sciences Partnerships for Biomedical Research in Arkansas - Admin Supplement Role: Principal Investigator |
| ASTA Suppport for INBRE (CORNETT, LAWRENCE E)May 9, 2014 - May 1, 2020 Arkansas Science & Technology Authority ASTA Support for INBRE Role: Principal Investigator |
| ASTASuppportforINBRE (CORNETT, LAWRENCE E)May 9, 2014 - May 1, 2020 Arkansas Science & Technology Authority ASTA Support for INBRE Role: Principal Investigator |
| IBN (CORNETT, LAWRENCE)Jun 1, 2002 - May 31, 2006 National Science Foundation Cloning and Functional Characterization of an Avian Pituitary Gland Vasotocin Receptor Role: Principal Investigator |
| IBN-0111006 (CORNETT, LAWRENCE E)Jun 1, 2002 - May 31, 2006 National Science Foundation Cloning and Functional Characterization of an Avian Pituitary Gland Vasotocin Receptor Role: Principal Investigator |
| P20GM103429 (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2025 NIH Partnerships for Biomedical Research in Arkansas Role: Principal Investigator |
| P20RR016460 (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2015 NIH Partnerships for Biomedical Research in Arkansas Role: Principal Investigator |
| 2001 (CORNETT, LAWRENCE)Sep 1, 2001 - Aug 31, 2004 US Department of Agriculture Neuroendocrine Control of Shell Gland Contractility in the Domestic Hen Role: Principal Investigator |
| 2001-35208-10842 (CORNETT, LAWRENCE E)Sep 1, 2001 - Aug 31, 2004 US Department of Agriculture Neuroendocrine Control of Shell Gland Contractility in the Domestic Hen Role: Principal Investigator |
| R01AM034507 (CORNETT, LAWRENCE E)Apr 1, 1985 - Mar 31, 1988 NIH BIOCHEMICAL STUDIES OF VASOPRESSIN RECEPTORS Role: Principal Investigator |
| R01DK034507 (CORNETT, LAWRENCE E)Apr 1, 1985 - Mar 31, 1988 NIH BIOCHEMICAL STUDIES OF VASOPRESSIN RECEPTORS Role: Principal Investigator |
| R01GM030669 (CORNETT, LAWRENCE E)Dec 1, 1983 - Jul 31, 1996 NIH ADRENERGIC RECEPTORS IN A SMOOTH MUSCLE CELL LINE Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Woessner AE, Anjum U, Salman H, Lear J, Turner JT, Campbell R, Beaudry L, Zhan J, Cornett LE, Gauch S, Quinn KP. Identifying and training deep learning neural networks on biomedical-related datasets. Brief Bioinform. 2024 Jul 23; 25(Supplement_1). PMID: 39041915.
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Abraham TH, Miller Robinson C, Siegel ER, Cornett LE. Using focused ethnography to inform biomedical research infrastructure enhancement at primarily undergraduate institutions. Adv Physiol Educ. 2024 Mar 01; 48(1):3-11. PMID: 37883733.
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Willis DE, Moore R, Selig JP, CarlLee S, Gurel-Headley MP, Cornett LE, McElfish PA. COVID-19 Booster Uptake: Are Hesitant Adopters Less Likely to Get a Booster Shot Than Nonhesitant Adopters? Behav Med. 2024 Jul-Sep; 50(3):260-268. PMID: 37722699.
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Willis DE, Reece S, Gurel-Headley M, Selig JP, Li J, Zimmerman S, Cornett LE, McElfish PA. Social processes, practical issues, and COVID-19 vaccination among hesitant adults. Vaccine. 2023 08 07; 41(35):5150-5158. PMID: 37423799.
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James L, Venable T, Caro A, Moran JH, Nesmith C, Gannon MA, Cornett LE. Development of a clinical and translational research curriculum for undergraduate students. J Clin Transl Sci. 2023; 7(1):e118. PMID: 37313383.
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Srivastava R, Cornett LE, Chaturvedi CM. Impact of estrogen and photoperiod on arginine vasotocin and VT3 receptor expression in the shell gland of quail. Front Biosci (Schol Ed). 2018 06 01; 10(2):372-385. PMID: 29772564.
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McSweeney JC, Hudson TJ, Prince L, Bene? H, Tackett AJ, Miller Robinson C, Koeppe R, Cornett LE. Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas. Adv Physiol Educ. 2018 Mar 01; 42(1):123-129. PMID: 29446316.
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Cornett LE, Kang SW, Kuenzel WJ. A possible mechanism contributing to the synergistic action of vasotocin (VT) and corticotropin-releasing hormone (CRH) receptors on corticosterone release in birds. Gen Comp Endocrinol. 2013 Jul 01; 188:46-53. PMID: 23499785.
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Koryakina Y, Jones SM, Cornett LE, Seely K, Brents L, Prather PL, Kofman A, Kurten RC. Effects of the ?-agonist, isoprenaline, on the down-regulation, functional responsiveness and trafficking of ?2-adrenergic receptors with N-terminal polymorphisms. Cell Biol Int. 2012; 36(12):1171-83. PMID: 22938397.
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Srivastava R, Cornett LE, Chaturvedi CM. Age-dependent expression of AVT and its oxytocic-like receptor VT3 in the shell gland of Japanese quail, Coturnix coturnix japonica. Gen Comp Endocrinol. 2010 Jan 01; 165(1):47-52. PMID: 19505466.
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Sharma D, Cornett LE, Chaturvedi CM. Corticosterone- or metapyrone-induced alterations in adrenal function and expression of the arginine vasotocin receptor VT2 in the pituitary gland of domestic fowl, Gallus gallus. Gen Comp Endocrinol. 2009 Apr; 161(2):208-15. PMID: 19523400.
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Sharma D, Cornett LE, Chaturvedi CM. Osmotic stress induced alteration in the expression of arginine vasotocin receptor VT2 in the pituitary gland and adrenal function of domestic fowl. Gen Comp Endocrinol. 2009 Feb 01; 160(3):216-22. PMID: 19073186.
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Srivastava R, Cornett LE, Chaturvedi CM. Effect of estrogen and its antagonist on the expression of arginine vasotocin (AVT) and its oxytocic-like receptor VT3 in the shell gland of Japanese quail, Coturnix coturnix japonica. Comp Biochem Physiol A Mol Integr Physiol. 2008 Dec; 151(4):551-9. PMID: 18678266.
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Jurkevich A, Berghman LR, Cornett LE, Kuenzel WJ. Immunohistochemical characterization of chicken pituitary cells containing the vasotocin VT2 receptor. Cell Tissue Res. 2008 Aug; 333(2):253-62. PMID: 18548280.
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Mikhailova MV, Blansett J, Jacobi S, Mayeux PR, Cornett LE. Transmembrane domain IV of the Gallus gallus VT2 vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor. J Biomed Opt. 2008 May-Jun; 13(3):031208. PMID: 18601532.
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Koryakina YA, Fowler TW, Jones SM, Schnackenberg BJ, Cornett LE, Kurten RC. Characterization of a panel of six beta2-adrenergic receptor antibodies by indirect immunofluorescence microscopy. Respir Res. 2008 Apr 18; 9:32. PMID: 18423037.
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Srivastava R, Cornett LE, Chaturvedi CM. Effect of photoperiod and estrogen on expression of arginine vasotocin and its oxytocic-like receptor in the shell gland of the Japanese quail. Comp Biochem Physiol A Mol Integr Physiol. 2007 Oct; 148(2):451-7. PMID: 17627858.
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Mikhailova MV, Mayeux PR, Jurkevich A, Kuenzel WJ, Madison F, Periasamy A, Chen Y, Cornett LE. Heterooligomerization between vasotocin and corticotropin-releasing hormone (CRH) receptors augments CRH-stimulated 3',5'-cyclic adenosine monophosphate production. Mol Endocrinol. 2007 Sep; 21(9):2178-88. PMID: 17536010.
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Mikhailova MV, Mayeux P, Jurkevich A, Kuenzel WJ, Periasamy A, Chen Y, Cornett LE. Hetero-oligomerization between vasotocin and corticotrophin-releasing hormone (CRH) receptors augments CRH-stimulated cyclic AMP production. Molecular Endocrinology. 2007; 21:2178-2188.
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Schnackenberg BJ, Jones SM, Pate C, Shank B, Sessions L, Pittman LM, Cornett LE, Kurten RC. Isoproterenol, a ?-agonist, attenuates EGF-stimulated wound closure in human airway epithelial cells. American Journal of Physiology. 2006; 290:L485-L491.
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Baeyens DA, Cornett LE. The cloned avian neurohypophysial hormone receptors. Comp Biochem Physiol B Biochem Mol Biol. 2006 Jan; 143(1):12-9. PMID: 16311051.
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Schnackenberg BJ, Jones SM, Pate C, Shank B, Sessions L, Pittman LM, Cornett LE, Kurten RC. The beta-agonist isoproterenol attenuates EGF-stimulated wound closure in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2006 Mar; 290(3):L485-91. PMID: 16227322.
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Gubrij KI, Chaturvedi CM, Ali N, Cornett LE, Kirby JD, Wilkerson J, Mikhailova M, Turner ML, Baeyens DA. Molecular cloning of an oxytocin-like receptor expressed in the chicken shell gland. Comp Biochem Physiol B Biochem Mol Biol. 2005 Sep; 142(1):37-45. PMID: 16005652.
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Jurkevich A, Berghman LR, Cornett LE, Kuenzel WJ. Characterization and immunohistochemical visualization of the vasotocin VT2 receptor in the pituitary gland of the chicken, Gallus gallus. Gen Comp Endocrinol. 2005 Aug; 143(1):82-91. PMID: 15993108.
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Jones SM, Hiller FC, Jacobi SE, Foreman SK, Pittman LM, Cornett LE. Enhanced beta2-adrenergic receptor (beta2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer. BMC Pharmacol. 2003 Dec 04; 3:15. PMID: 14656380.
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Cornett LE, Kirby JD, Vizcarra JA, Ellison JC, Thrash J, Mayeux PR, Crew MD, Jones SM, Ali N, Baeyens DA. Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor. Regul Pept. 2003 Feb 28; 110(3):231-9. PMID: 12573805.
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Chaturvedi CM, Chowdhary A, Cornett LE. Water deprivation and diurnal changes in plasma arginine vasotocin and mesotocin in the domestic hen (Gallus domesticus). Chronobiology International. 2001; 18:947-956.
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Baeyens DA, Kelly JG, Foreman SK, Jacobi SE, McGraw DW, Cornett LE. Transcriptional regulation of ?2-adrenergic receptor gene expression in the developing male rat liver. 1996.
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Chaturvedi CM, Zheng Z, Shimada K, Cornett LE, Koike TI. Changes in poly(A) tail length of arginine vasotocin ribonucleic acid in the hypothalamus of water deprived chickens. General and Comparative Endocrinology. 1996; 103:316-322.
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McGraw DW, Jacobi SE, Hiller FC, Cornett LE. Cis-acting regulatory elements in the distal 5’-flanking region of the rat ?2-adrenergic receptor gene. 1995.
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Randall EB, Foreman SK, Baeyens DA, Cornett LE. A Mr 85,000 protein binds selectively to an AU-containing segment of the ?2-adrenergic receptor mRNA 3’-untranslated region. 1995.
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Cornett LE, McGraw DW, Dicker-Brown A, Deng C-I. Identification of an alternatively spliced intron in the 5’-flanking region of the rat ?1B-adrenergic receptor gene. 1995.
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Baeyens DA, Foreman SK, MacLeod V, Cornett LE. Destabilitzation of hepatic ?2-adrenergic receptor mRNA during development is associated with a Mr 85,000 protein that binds to the ?2-adrenergic receptor mRNA 3’-untranslated region. 1994.
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Chaturvedi CM, Zheng Z, Cornett LE, Koike TI. Central and peripheral vasotocin gene expression in chickens detected by reverse transcription-polymerase chain reaction. 1994.
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McGraw DW, Chai SE, Hiller FC, Cornette LE. *2-Adrenergic receptor and mRNA levels in rat lungs following in vivo administration of glucocorticoids. 1993.
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Cornett LE. Textbook of Physiology. The Adrenal Medulla. 1989.
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Cornett LE. Peptide Hormone Receptors. Vasopressin receptors. 1987.
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Norris JS, Cornett LE, Harris SE, Nag A, Rossby P, Srivastava A, MacLeod SL, Smith RG. Advances in Gene Technology: Molecular Biology of the Endocrine System. Investigation of glucocorticoid receptor regulation of autocrine growth in a smooth muscle tumor cell line. 1986.
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Cornett LE, Bavister BD, Meizel S. Adrenergic stimulation of fertilizing ability of hamster spermatozoa. Biology of Reproduction. 1980; 20:925-929.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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1989 | 1 | 1993 | 1 | 1994 | 2 | 1995 | 3 | 1996 | 2 | 2001 | 1 | 2003 | 2 | 2005 | 4 | 2006 | 1 | 2007 | 3 | 2008 | 5 | 2009 | 2 | 2012 | 1 | 2013 | 1 | 2018 | 2 | 2023 | 4 | 2024 | 1 |
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