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Anna Radominska-Pandya

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
DivisionBiochemistry & Molecular UGTs
Address6R27A Barton Research
324 S. Elm St.
Mail Slot # 516
Little Rock AR 72205
Phone501-686-5414
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPharmaceutics, College of Pharmacy


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016; 11(12):e0167240. PMID: 27936172.
      View in: PubMed
    2. Dates CR, Fahmi T, Pyrek SJ, Yao-Borengasser A, Borowa-Mazgaj B, Bratton SM, Kadlubar SA, Mackenzie PI, Haun RS, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines. Cancer Biol Ther. 2015; 16(5):714-23. PMID: 25996841; PMCID: PMC4622877.
    3. Karmakar A, Xu Y, Mustafa T, Kannarpady G, Bratton SM, Radominska-Pandya A, Crooks PA, Biris AS. Nanodelivery of Parthenolide Using Functionalized Nanographene Enhances its Anticancer Activity. RSC Adv. 2015 Jan 01; 5(4):2411-2420. PMID: 25574376.
      View in: PubMed
    4. Saeed LM, Mahmood M, Pyrek SJ, Fahmi T, Xu Y, Mustafa T, Nima ZA, Bratton SM, Casciano D, Dervishi E, Radominska-Pandya A, Biris AS. Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells. J Appl Toxicol. 2014 Nov; 34(11):1188-99. PMID: 25220893; PMCID: PMC4416215.
    5. Greer AK, Dates CR, Starlard-Davenport A, Edavana VK, Bratton SM, Dhakal IB, Finel M, Kadlubar SA, Radominska-Pandya A. A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives. Drug Metab Dispos. 2014 Sep; 42(9):1392-400. PMID: 24917585; PMCID: PMC4152870.
    6. Biris AS, Radominska-Pandya A. Special issue: nanotechnology and disease. Drug Metab Rev. 2014 May; 46(2):127. PMID: 24678874.
      View in: PubMed
    7. Greer AK, Madadi NR, Bratton SM, Eddy SD, Mazerska Z, Hendrickson HP, Crooks PA, Radominska-Pandya A. Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases. Chem Res Toxicol. 2014 Apr 21; 27(4):536-45. PMID: 24571610; PMCID: PMC4002122.
    8. Prather PL, FrancisDevaraj F, Dates CR, Greer AK, Bratton SM, Ford BM, Franks LN, Radominska-Pandya A. CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun. 2013 Nov 15; 441(2):339-43. PMID: 24148245; PMCID: PMC3860589.
    9. Seely KA, Patton AL, Moran CL, Womack ML, Prather PL, Fantegrossi WE, Radominska-Pandya A, Endres GW, Channell KB, Smith NH, McCain KR, James LP, Moran JH. Forensic investigation of K2, Spice, and "bath salt" commercial preparations: a three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds. Forensic Sci Int. 2013 Dec 10; 233(1-3):416-22. PMID: 24314548.
      View in: PubMed
    10. Fantegrossi WE, Moran JH, Radominska-Pandya A, Prather PL. Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to ?(9)-THC: mechanism underlying greater toxicity? Life Sci. 2014 Feb 27; 97(1):45-54. PMID: 24084047; PMCID: PMC3945037.
    11. Patton AL, Seely KA, Chimalakonda KC, Tran JP, Trass M, Miranda A, Fantegrossi WE, Kennedy PD, Dobrowolski P, Radominska-Pandya A, McCain KR, James LP, Endres GW, Moran JH. Targeted metabolomic approach for assessing human synthetic cannabinoid exposure and pharmacology. Anal Chem. 2013 Oct 01; 85(19):9390-9. PMID: 23987522.
      View in: PubMed
    12. Patton AL, Chimalakonda KC, Moran CL, McCain KR, Radominska-Pandya A, James LP, Kokes C, Moran JH. K2 toxicity: fatal case of psychiatric complications following AM2201 exposure. J Forensic Sci. 2013 Nov; 58(6):1676-80. PMID: 23822805; PMCID: PMC4319529.
    13. Chimalakonda KC, James LP, Radominska-Pandya A, Moran JH. Sulfaphenazole and a-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. Drug Metab Lett. 2013 Mar; 7(1):34-8. PMID: 24329780; PMCID: PMC4154622.
    14. Medina-Bolivar F, Radominska-Pandya A, Bratton SM, Smith K, Karydis A, Garcia-Godoy F, Nopo-Olazabal L, Ogutu L, Yang T, Marsh Z, Joshee N, Patel A, Tollett CA, Nopo-Olazabal C. Biotechnological approaches to discover and produce health beneficial compounds from hairy roots. 4th Annual Conference of the American Council for Medicinally Active Plants. 2013.
    15. Radominska-pandya A. Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer. Sydney International Nanomedicine Conference. 2013.
    16. Radominska-Pandya A, Fahmi T, FrancisDevaraj F, Dates CR, Greer AK, Pyrek SJ, Bratton SM. Human UDP-glucuronosyltransferases: A Novel Role in Modulating Cytotoxicity in Cancer. 2nd UAMS Showcase of Medical Discoveries: A Focus on Nanomedicine. 2013.
    17. Pawlowska M, Chu R, Fedejko-Kap B, Augustin E, Mazerska Z, Radominska-Pandya A, Chambers TC. Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use. Drug Metab Dispos. 2013 Feb; 41(2):414-21. PMID: 23160818; PMCID: PMC3558869.
    18. Chimalakonda KC, Seely KA, Bratton SM, Brents LK, Moran CL, Endres GW, James LP, Hollenberg PF, Prather PL, Radominska-Pandya A, Moran JH. Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. Drug Metab Dispos. 2012 Nov; 40(11):2174-84. PMID: 22904561; PMCID: PMC3477201.
    19. Fedejko-Kap B, Bratton SM, Finel M, Radominska-Pandya A, Mazerska Z. Role of human UDP-glucuronosyltransferases in the biotransformation of the triazoloacridinone and imidazoacridinone antitumor agents C-1305 and C-1311: highly selective substrates for UGT1A10. Drug Metab Dispos. 2012 Sep; 40(9):1736-43. PMID: 22659092; PMCID: PMC3422538.
    20. Seely KA, Brents LK, Radominska-Pandya A, Endres GW, Keyes GS, Moran JH, Prather PL. A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Chem Res Toxicol. 2012 Apr 16; 25(4):825-7. PMID: 22404317; PMCID: PMC3921679.
    21. Brents LK, Gallus-Zawada A, Radominska-Pandya A, Vasiljevik T, Prisinzano TE, Fantegrossi WE, Moran JH, Prather PL. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol. 2012 Apr 01; 83(7):952-61. PMID: 22266354; PMCID: PMC3288656.
    22. Dates CR, Yao-Borengasser A, Bratton SM, Pyrek SJ, Bernock LJ, Medina-Bolivar F, Kadlubar S, Borrelli MJ, Mackenzie PI, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity. 18th North American Regional ISSX Meeting. 2012.
    23. Radominska-Pandya A, Karmakar A, Bratton SM, Xu Y, Mahmood M, Ghosh A, Biris AS. Functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor genes to cancer cells. Experimental Biology 2012. 2012.
    24. Bratton SM, Dates CR, Nair V, Nopo-Olazabal L, Francisdevaraj F, Medina-Bolivar F, Radominska-Pandya A. Natural prenylated resveratrol analogs arachidin-1 and arachidin-3: Altered glucuronidation could lead to enhanced bioavailability. 3rd Annual Conference of the American Council for Medicinally Active Plants. 2012.
    25. Greer AK, Bratton SM, Dates CR, Francisdevaraj F, Rajasekaran M, Prather PL, Radominska-Pandya A. Gambogic acid and its analogues are novel substrates for human UDP-glucuronosyltransferase and bind cannabinoid receptors CB1 and CB2. 3rd Annual Conference of the American Council for Medicinally Active Plants. 2012.
    26. Dates CR, Yao-Borengasser A, Bratton SM, Pyrek SJ, Medina-Bolivar F, Kadlubar S, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Role in modulation of breast cancer cell proliferation and drug toxicity. 6th Annual National Conference on Health Disparities. 2012.
    27. Greer AK, Bratton SM, Vo D, Ostojic N, Pyrek S, Francisdevaraj F, Medina-Bolivar F, Haun R, Radominska-Pandya A. Human UDP-Glucuronosyltransferases: Role in modulation of pancreatic cancer cell proliferation and drug toxicity. 18th North American Regional ISSX Meeting. 2012.
    28. Pawlowska M, Chu R, Bratton SM, Augustin E, Mazerska Z, Chambers TC, Radominska-Pandya A. Glucuronides of antitumor agents C-1311 and C-1305 modulate cytotoxicity in cancer cells. Experimental Biology 2012. 2012.
    29. Francisdevaraj F, Bratton SM, Ostojic N, Pyrek SJ, Vo D, Greer AK, Medina-Bolivar F, Haun R, Radominska-Pandya A. Naturally derived compounds and their role in cytotoxicity of Pancreatic cancer cell lines. 6th Annual National Conference on Health Disparities. 2012.
    30. Bratton SM, Mosher CM, Khallouki F, Finel M, Court MH, Moran JH, Radominska-Pandya A. Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2012 Jan; 340(1):46-55. PMID: 21972237; PMCID: PMC3251030.
    31. Brents LK, Medina-Bolivar F, Seely KA, Nair V, Bratton SM, Nopo-Olazabal L, Patel RY, Liu H, Doerksen RJ, Prather PL, Radominska-Pandya A. Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors. Xenobiotica. 2012 Feb; 42(2):139-56. PMID: 21970716; PMCID: PMC3608422.
    32. Fedejko-Kap B, Niemira M, Radominska-Pandya A, Mazerska Z. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells. Xenobiotica. 2011 Dec; 41(12):1044-55. PMID: 21859392.
      View in: PubMed
    33. Höglund C, Sneitz N, Radominska-Pandya A, Laakonen L, Finel M. Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens. Steroids. 2011 Dec 11; 76(13):1465-73. PMID: 21846474; PMCID: PMC3188330.
    34. Chimalakonda KC, Moran CL, Kennedy PD, Endres GW, Uzieblo A, Dobrowolski PJ, Fifer EK, Lapoint J, Nelson LS, Hoffman RS, James LP, Radominska-Pandya A, Moran JH. Solid-phase extraction and quantitative measurement of omega and omega-1 metabolites of JWH-018 and JWH-073 in human urine. Anal Chem. 2011 Aug 15; 83(16):6381-8. PMID: 21740038; PMCID: PMC3155992.
    35. Chimalakonda KC, Bratton SM, Le VH, Yiew KH, Dineva A, Moran CL, James LP, Moran JH, Radominska-Pandya A. Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases. Drug Metab Dispos. 2011 Oct; 39(10):1967-76. PMID: 21746969; PMCID: PMC3186213.
    36. Karmakar A, Bratton SM, Dervishi E, Ghosh A, Mahmood M, Xu Y, Saeed LM, Mustafa T, Casciano D, Radominska-Pandya A, Biris AS. Ethylenediamine functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor p53 gene to breast cancer MCF-7 cells. Int J Nanomedicine. 2011; 6:1045-55. PMID: 21720516; PMCID: PMC3124390.
    37. Moran CL, Le VH, Chimalakonda KC, Smedley AL, Lackey FD, Owen SN, Kennedy PD, Endres GW, Ciske FL, Kramer JB, Kornilov AM, Bratton LD, Dobrowolski PJ, Wessinger WD, Fantegrossi WE, Prather PL, James LP, Radominska-Pandya A, Moran JH. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Anal Chem. 2011 Jun 01; 83(11):4228-36. PMID: 21506519; PMCID: PMC3105467.
    38. Fedejko-Kap B, Bratton SM, Finel M, Mazerska Z, Radominska-Pandya A. The role of intestine and liver in glucuronidation of the imidazo- and triazoloacridinone antitumor agents, C-1311 and C-1305 glucuronidation: High affinity substrates for UGT1A10. 17th North American Regional ISSX Meeting. 2011.
    39. Radominska-Pandya A, Yiew KH, Bratton SM, Le V-H, Gallus-Zawada AE, Moran C, James LP, Moran JH. Conjugation of synthetic cannabinoids in K2/Spice by human UDP-glucuronosyltransferase (UGTs). Experimental Biology 2011. 2011.
    40. Radominska-Pandya A, Yiew KH, Bratton SM, Gallus-Zawada AE, Fantegrossi WE, James LP, Moran C, Prather P, Moran JH. Biotransformation of abused synthetic cannabinoids in K2/Spice by human hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs). 4th Asia Pacific Regional ISSX Meeting. 2011.
    41. Radominska-Pandya A, Bratton SM, Chib S, Blevins JM, Gallus-Zawada AE, Moran C, James LP, Moran JH. Oxidation of abused synthetic cannabinoids in K2/Spice by human cytochromes P450. Experimental Biology 2011. 2011.
    42. Karmakar, A, Bratton, S M, Dervishi, E, Ghosh, A, Mohmood, M, Xu, Y, Saeed, L M, Mustafa, T, Casciano, D, Radominska-Pandya A, Biris, A S. Ethylenediamine Functionalized-Single-Walled Nanotube (f-SWNT)-Assisted in Vitro Delivery of Oncogene Suppressor p53 Gene to Breast Cancer MCF-7 Cells. Int J Nanomedicine. 2011; 6:1045–1055.
    43. Radominska-Pandya A, Karmakar A, Bratton SM, Xu Y, Mahmood M, Biris AS. Targeted nanoparticle delivery of tumor suppressing p53 and UDP-glucuronosyltransferase (UGT) genes into breast cancer cells. Nanotechnology and Healthcare Conference. 2011.
    44. Chimalakonda KC, Brents LK, Moran CL, Prather PL, James LP, Radominska-Pandya A, Moran JH. Human Metabolism of JWH-018 and JWH-073 and In Vitro Characterization of Major Omega and Omega-1 Metabolites. 17th North American Regional ISSX Meeting. 2011.
    45. Radominska-Pandya A, Chimalakonda KC, Bratton SM, Fedejko-Kap B, Le V-H, Yiew KH, Moran CL, James LP, Moran JH. Biotransformation of Abused Synthetic Cannabinoids, JWH-018 and JWH-073, by Human Cytochromes P450 and UDP-glucuronosyltransferases. 17th North American Regional ISSX Meeting. 2011.
    46. Brents LK, Gallus-Zawada A, Radominska-Pandya A, Fantegrossi WE, Moran JH, Prather PL. A mono-hydroxylated metabolite of the K2 synthetic cannabinoid JWH-073 displays high affinity neutral antagonism at CB1 receptors. 21st Annual Symposium of the International Cannabinoid Research Society. 2011.
    47. Radominska-Pandya A, Bratton SM, Redinbo MR, Miley MJ. The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families. Drug Metab Rev. 2010 Feb; 42(1):133-44. PMID: 19821783; PMCID: PMC3192453.
    48. Radominska-Pandya A. Preface. Drug Metab Rev. 2010 Feb; 42(1):1-2. PMID: 20070243.
      View in: PubMed
    49. Radominska-Pandya A, Nair V, Bratton SM, Gallus-Zawada AE, Prather PL, Medina-Bolivar F. Human UDP-glucuronosyltransferases (UGTs) are involved in the metabolism of the natural resveratrol analogues arachidin-1, arachidin-3 and piceatannol. Experimental Biology 2010. 2010.
    50. Radominska-Pandya A, Karmakar A, Bratton SM, Xu Y, Mahmood M, Gallus-Zawada AE, Biris AS. Targeted nanoparticle delivery of tumor suppressing UDP-glucuronosyltransferase (UGT) genes into cancer cells. Experimental Biology 2010. 2010.
    51. Miller GP, Jones DR, Sullivan SZ, Mazur A, Owen SN, Mitchell NC, Radominska-Pandya A, Moran JH. Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans. Chem Res Toxicol. 2009 Jul; 22(7):1239-45. PMID: 19408964; PMCID: PMC2819755.
    52. Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids. Drug Metab Dispos. 2009 Jul; 37(7):1496-504. PMID: 19339377; PMCID: PMC2698943.
    53. Moran JH, Pack LM, Gallus-Zawada AE, Yew N, Bratton SM, Owen SN, Jones DR, Miller GP, Radominska-Pandya A. Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs). 16th North American Regional ISSX meeting. 2009.
    54. Jones DR, Kim S-Y, Guderyon M, Yun C-H, Radominska-Pandya A, Moran JH, Miller GP. Cytochrome P450 Capacity to Metabolize Warfarin Limited by Feedback Inhibition. 16th North American Regional ISSX meeting. 2009.
    55. Mazur A, Bratton SM, Miller GP, Finel M, Radominska-Pandya A. The glucuronidation of native and oxidized estrogens can be effectively inhibited by compounds structurally related to UDP-glucuronic acid in human recombinant UGT1A10. Experimental Biology 2009. 2009.
    56. Bratton SM, Laakkonen L, Patana A-S, Mazur A, Miller GP, Finel M, Radominska-Pandya A. Comparative characterization of UDP-glucuronic acid (UDP-GlcUA) binding-site directed inhibitors with human UGT2B7 and 1A10. Experimental Biology 2009. 2009.
    57. Moran JH, Jones D, Bratton SM, Gallus-Zawada AE, Miller GP, Radominska-Pandya A. Separation and Glucuronidation of R- and S-Hydroxywarfarins by Human Recombinant UDP-Glucuronosyltransferases (UGTs). 3rd Asian Pacific ISSX Meeting. 2009.
    58. Radominska-Pandya A, Mazur A, Bratton SM, Finel M, Moran JH, Miller GP. Simultaneous glucuronidation of native and oxidized estrogens and warfarin by human recombinant UGT1A10: Potential for drug-drug interactions. 3rd Asian Pacific ISSX Meeting. 2009.
    59. Brezden A, Mazur A, Xiong Y, Miller GP, Finel M, Radominska-Pandya A. Characterization of mutation in the 395DQxD398 motif of the glucuronic acid binding site in human UGT1A6: Comparison to UGT1A10. 2009.
    60. Itäaho K, Court MH, Uutela P, Kostiainen R, Radominska-Pandya A, Finel M. Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. Drug Metab Dispos. 2009 Apr; 37(4):768-75. PMID: 19116261; PMCID: PMC2680538.
    61. Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. Drug Metab Dispos. 2008 Nov; 36(11):2211-8. PMID: 18725508; PMCID: PMC2812427.
    62. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues. Steroids. 2008 Jul; 73(6):611-20. PMID: 18374377; PMCID: PMC2408449.
    63. Lu Y, Bratton S, Heydel JM, Radominska-Pandya A. Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells. Drug Metab Pharmacokinet. 2008; 23(5):364-72. PMID: 18974614; PMCID: PMC3129696.
    64. Mazur A, Laakkonen L, Bratton SM, Gallus-Zawada A, Miller GP, Finel M, Radominska-Pandya A. The effect of inhibitors, structurally related to UDP-glucuronic acid, on human recombinant UGT1A10. 15th North American Regional ISSX meeting. 2008.
    65. Radominska-Pandya A, Mazur A, Lichti CF, Gallus- Zawada, Zielinska AK, Bratton SM, Moran JH. Human Hepatic and extrahepatic UDP-glucuronosyltransferase (UGTs) enzymes involved in the metabolism of cannabinoids. Experimental Biology 2008. 2008.
    66. Radominska-Pandya A, Miley M, Xiong Y, Mazur A, Zielinska AK, Bratton SM, Gallus-Zawada A, Miller GP, Finel M, Moran JH, Redinbo M. Identification and Characterization of the UDP-glucuronic Acid and Substrate Binding Sites of Human UDP-glucuronosyltransferases: Crystallization and Photoaffinity Labeling. 15th North American Regional ISSX meeting. 2008.
    67. Mazur A, Xiong Y, Zielinska AK, Moran JH, Miller GP, Finel M, Radominska-Pandya A. Substrate binding and specificity of human UGT 1A10. 12th International Glucuronidation and UGT International Workshop 2008. 2008.
    68. Radominska-Pandya A. Overview: Cyrstallography, modeling and catalytic activity of human UDP-glucuronosyltransferases. 12th International Glucuronidation and UGT International Workshop 2008. 2008.
    69. Xiong Y, Patana AS, Miley MJ, Zielinska AK, Bratton SM, Miller GP, Goldman A, Finel M, Redinbo MR, Radominska-Pandya A. The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. Drug Metab Dispos. 2008 Mar; 36(3):517-22. PMID: 18048489; PMCID: PMC2275115.
    70. Zielinska A, Lichti CF, Bratton S, Mitchell NC, Gallus-Zawada A, Le VH, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases. J Pharmacol Exp Ther. 2008 Jan; 324(1):139-48. PMID: 17921187; PMCID: PMC2275122.
    71. Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. Steroids. 2008 Jan; 73(1):139-47. PMID: 17981312; PMCID: PMC2238686.
    72. Li X, Bratton S, Radominska-Pandya A. Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes. Drug Metab Pharmacokinet. 2007 Jun; 22(3):152-61. PMID: 17603215; PMCID: PMC2275121.
    73. Miley MJ, Zielinska AK, Keenan JE, Bratton SM, Radominska-Pandya A, Redinbo MR. Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7. J Mol Biol. 2007 Jun 01; 369(2):498-511. PMID: 17442341; PMCID: PMC1976284.
    74. Zielinska A, Lichti CF, Bratton SM, Gallus-Zawada A, Mitchell NC, Finel M, Radominska-Pandya A, Moran JH. Glucuronidation of Warfarin Metabolites by human Recombinant UDP-Glucuronosyltransferases (UGTs). Experimental Biology 2007. 2007.
    75. Radominska-Pandya A, Zielinska AK, Collom SL, Jamakhandi AP, Bratton SM, Tackett AJ, Finel M, Miller GP. Similarities between chtochrome P450 (CYP)2C1 and UDP-glucuronosyltransferase (UGT)1A10 phenol active site residues as identified by photoaffinity labeling (PAL), MS, and homology modeling. 15th International Conference on Cytochromes P450. 2007.
    76. Zielinska AK, Lichti CF, Bratton SM, Gallus-Zawada AE, Mitchell NC, Moran JH, Radominska-Pandya A. Glucuronidation of Hydroxylated Derivatives of Warfarin by Human UGT1A10; Identification of Amino acid Motif Involved in Warfarin Binding. 8th International ISSX Meeting. 2007.
    77. Xiong Y, Bratton SM, Zielinska AK, Finel M, Radominska-Pandya A. The Aspartic Acid Of the DxxD Motif Within The C-Terminal region Of Human UDP-Glucuronosyltransferase 1A10 is Critical To The Binding of UDP-Glucuronic Acid. Experimental Biology 2007. 2007.
    78. Radominska-Pandya A, Zielinska AK, Xiong Y, Bratton SM, Gallus-Zawada AE. Identification of Substrate Binding Sites of Human UGT1A10; Implication for Multiple Binding Sites. 8th International ISSX Meeting. 2007.
    79. Starland-Daveport A, Lyn-Cook B, Radominska-Pandya A. Estradiol regulates the expression of UDP-glucuronosyltransferase 1A10 in normal and malignant human breast cells. Experimental Biology 2007. 2007.
    80. Starlard-Davenport A, Xiong Y, Bratton S, Gallus-Zawada A, Finel M, Radominska-Pandya A. Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10. Steroids. 2007 Jan; 72(1):85-94. PMID: 17174996; PMCID: PMC1829494.
    81. Collom SL, Jamakhandi AP, Tackett AJ, Radominska-Pandya A, Miller GP. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling. Arch Biochem Biophys. 2007 Mar 01; 459(1):59-69. PMID: 17222385; PMCID: PMC1994253.
    82. Sabolovic N, Humbert AC, Radominska-Pandya A, Magdalou J. Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells. Biopharm Drug Dispos. 2006 May; 27(4):181-9. PMID: 16477579.
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    83. Xiong Y, Bernardi D, Bratton S, Ward MD, Battaglia E, Finel M, Drake RR, Radominska-Pandya A. Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. Biochemistry. 2006 Feb 21; 45(7):2322-32. PMID: 16475821.
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    84. Ronis MJ, Little JM, Barone GW, Chen G, Radominska-Pandya A, Badger TM. Sulfation of the isoflavones genistein and daidzein in human and rat liver and gastrointestinal tract. J Med Food. 2006; 9(3):348-55. PMID: 17004897.
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    85. Starland-Daveport A, Bratton S, Finel M, Radominska-Pandya A. Human UDP-glucuronosyltransferases involved in estrogen glucuronidation: kinetic and estrogen biniding site. 17th International Symposium of the Journel of Steroid Biochemistry and Molecular Biology. 2006.
    86. Starland-Daveport A, Cook B, Heydel J-M, Radominska-Pandya A. alteration of UDP-glucuronosyltransferase expression in malignant human breast tissue. 17th International symposium of the Journel of Steroid Biochemistry and Molecular Biology. 2006.
    87. Starland-Daveport A, Cook B, Radominska-Pandya A. Characterization of UDP-glucuronosyltransferases in normal and carcinogenic human breast tissue. Experimental Biology 2006. 2006.
    88. Starland-Daveport A, Bratton S, Finel M, Radominska-Pandya A. Phe90 is a crucial amino acid within the estrogen biniding site of the human UDP-glucuronosyltransferase 1A10. Expermental Biology 2006. 2006.
    89. Finel M, Li X, Gardner-Stephen D, Bratton S, Mackenzie PI, Radominska-Pandya A. Human UDP-glucuronosyltransferase 1A5: identification, expression, and activity. J Pharmacol Exp Ther. 2005 Dec; 315(3):1143-9. PMID: 16120810.
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    90. Lu Y, Heydel JM, Li X, Bratton S, Lindblom T, Radominska-Pandya A. Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element. Drug Metab Dispos. 2005 Jul; 33(7):937-46. PMID: 15821044; PMCID: PMC2652669.
    91. Radominska-Pandya A, Bratton S, Little JM. A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years. Curr Drug Metab. 2005 Apr; 6(2):141-60. PMID: 15853765.
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    92. Radominska-Pandya A, Ouzzine M, Fournel-Gigleux S, Magdalou J. Structure of UDP-glucuronosyltransferases in membranes. Methods Enzymol. 2005; 400:116-47. PMID: 16399347.
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    93. Xiong Y, Bernardi D, Bratton S, Ward MD, Battagia E, Finel M, Drake R, Radominska-Pandya A. Phenylalanine90 is a crucial amino acid localized with the phenol binding site of human UDP-glucuronosyltransferases 1A10 as determined by photoaffinity labeling mass spectrometry and site directed mutagenesis. ISSX-JSSX. 2005.
    94. Radominska-Pandya A, Ouzzine M, Fourmel-Gigleux S, Magdalou J. Methods in Enzymology. Structure of UDP-glucuronosyltransferases in membranes. 2005.
    95. Lu Y, Radominska-Pandya A. Effects of retionds and their oxidized derivatives on UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 mRNA expression in Caco-2 cells. Experimental Biology. 2005.
    96. Li X, Gardner-Stephen DA, Lu Y, Heydel J-M, Bratton S, Mackenzie PI, Radominska-Pandya A. Human UDP-glucuronosyltransferases UGTs) 1A3 and 1A4 are induced by ligands of the aryl hydrocarbon receptor (AhR). Experimental Biology. 2005.
    97. Sabolovic N, Heydel JM, Li X, Little JM, Humbert AC, Radominska-Pandya A, Magdalou J. Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract. Biochim Biophys Acta. 2004 Nov 18; 1675(1-3):120-9. PMID: 15535975.
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    98. Little JM, Kurkela M, Sonka J, Jäntti S, Ketola R, Bratton S, Finel M, Radominska-Pandya A. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. J Lipid Res. 2004 Sep; 45(9):1694-703. PMID: 15231852.
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    99. Xie W, Uppal H, Saini SP, Mu Y, Little JM, Radominska-Pandya A, Zemaitis MA. Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism. Drug Discov Today. 2004 May 15; 9(10):442-9. PMID: 15109949.
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    100. Gardner-Stephen D, Heydel JM, Goyal A, Lu Y, Xie W, Lindblom T, Mackenzie P, Radominska-Pandya A. Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression. Drug Metab Dispos. 2004 Mar; 32(3):340-7. PMID: 14977869; PMCID: PMC2652677.
    101. Radominska-Pandya A, Little JM, Kurkela M, Sonka J, Jantti S, Ketola R, Bratton S, Finel M. Biosynthesis of oxidized fatty acids and prostaglandins by human UDP-Glucuronosyltransferases. ISSX Vancouver Canada. 2004.
    102. Radominska-pandya A, Little JM, Bull AW. Glucuronidation of fatty acids and prostaglandins by human UDP-glucuronosyltransferases in Drug Metabolism and Transport. Molecular Method and Mechanisms. 2004.
    103. Radominska-Pandya A, Little JM, Kurkela M, Sonka J, Jantti S, Ketola R, Bratton S, Finel M. Biosynthesis of glucuronides of oxidized fatty acids and prostaglandins by human UDP-glucuronosyltransferases. 7th International ISSX Meeting. 2004.
    104. Radominska-Pandya A, Mackenzie Pl, Xie W. Transcriptional regulation of UDP-glucuronosyltransferases. Drug Metabolism and Transport Transcriptional regulation of UDP-glucuronosyltransferases. 2004.
    105. Radominska-Pandya A, Lu Y, Hydel J-M. Regulation of UGT2B7 expression by bile acids and retinoids. XIth International Workshop on Glucuronidation. 2004.
    106. Lu Y, Hydel J-M, Li X, Bratton X, Gardner-Stephen D, Mackenzie P, Radominska-Pandya A. Lithocholic acid medicated FXR Suppresses UDP-Glucuronosyltransferases 2B7 expression in Caco-2 cells. 7th International ISSX Meeting. 2004.
    107. Mackenzie PI, Gregory PA, Gardner-Stephen DA, Lewinsky RH, Jorgensen BR, Nishiyama T, Xie W, Radominska-Pandya A. Regulation of UDP glucuronosyltransferase genes. Curr Drug Metab. 2003 Jun; 4(3):249-57. PMID: 12769669.
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    108. Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci U S A. 2003 Apr 01; 100(7):4150-5. PMID: 12644700; PMCID: PMC153063.
    109. Antonio L, Xu J, Little JM, Burchell B, Magdalou J, Radominska-Pandya A. Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7. Arch Biochem Biophys. 2003 Mar 15; 411(2):251-61. PMID: 12623074.
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    110. Chen G, Zhang D, Jing N, Yin S, Falany CN, Radominska-Pandya A. Human gastrointestinal sulfotransferases: identification and distribution. Toxicol Appl Pharmacol. 2003 Mar 15; 187(3):186-97. PMID: 12662902.
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    111. Mackenzie P, Little JM, Radominska-Pandya A. Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7. Biochem Pharmacol. 2003 Feb 01; 65(3):417-21. PMID: 12527334.
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    112. Radominska-Pandya A, Hydel J-M. Lithocholic acid decreases expression of UDP-glucuronosyltransferases 2B7 inCaCo2 cell but not HepG2 cells. Experimental Biology 2003. 2003.
    113. Sabolovic N, Antorio L, Radominska-Pandya A, Humbert A-C. Glucuronidation of Polyphenols in rat and in man. First International conference on Polyphenols and health. 2003.
    114. Coles BF, Chen G, Kadlubar FF, Radominska-Pandya A. Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals. Arch Biochem Biophys. 2002 Jul 15; 403(2):270-6. PMID: 12139976.
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    115. Mehta KD, Radominska-Pandya A, Kapoor GS, Dave B, Atkins BA. Critical role of diacylglycerol- and phospholipid-regulated protein kinase C epsilon in induction of low-density lipoprotein receptor transcription in response to depletion of cholesterol. Mol Cell Biol. 2002 Jun; 22(11):3783-93. PMID: 11997513; PMCID: PMC133812.
    116. Little JM, Williams L, Xu J, Radominska-Pandya A. Glucuronidation of the dietary fatty acids, phytanic acid and docosahexaenoic acid, by human UDP-glucuronosyltransferases. Drug Metab Dispos. 2002 May; 30(5):531-3. PMID: 11950783.
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    117. Radominska-Pandya A, Chen G. Photoaffinity labeling of human retinoid X receptor beta (RXRbeta) with 9-cis-retinoic acid: identification of phytanic acid, docosahexaenoic acid, and lithocholic acid as ligands for RXRbeta. Biochemistry. 2002 Apr 16; 41(15):4883-90. PMID: 11939783.
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    118. Radominska-Pandya A, Pokrovskaya ID, Xu J, Little JM, Jude AR, Kurten RC, Czernik PJ. Nuclear UDP-glucuronosyltransferases: identification of UGT2B7 and UGT1A6 in human liver nuclear membranes. Arch Biochem Biophys. 2002 Mar 01; 399(1):37-48. PMID: 11883901.
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    119. Radominska-Pandya A, Lindblom TH, Czernik PJ. Nuclear receptor activation of drug metabolism enzymes in humans and C elegans. 18th European Workshop on Drug Metabolism. 2002.
    120. Mackenzie Pl, Gregony PA, Gardner-Stephen DA, Lewinsky RH, Jorgensen BR, Nishiyama T, Radominska-Pandya A. Transcriptional regulation of UDP-glucuronosyltransferases genes. Australian Health and Medical Research Congress. 2002.
    121. Sonka J, Little JM, Samokyszyn V, Radominska-Pandya A. Glucuronidation of arachidonic acid, 20-HETE and prostaglandin E2 by human hepatic and intestinal UDR-glucuronosyltransferases and recombinant UGT2B7. 2002; 34, Supp. 1:194 - .
    122. Radominska-Pandya A, Xu J, Little JM, Antonio L, Tephly TR, Magdalou J. The effects of inhibitors structurally related to UDP-glucuronic acid on human recombinant UGT2B7 expreesesd in HK293 cells. Experimental Biology 2002. 2002.
    123. Gardner-Stephen DA, Radominska-Pandya A, Mackenzie Pl. Coordination induction of proteins involved in drug metabolism and export by the pregnane X Receptor (PXR). Australian Health and Medical Research Congress. 2002.
    124. Radominska-Pandya A, Xie W, Hydel JM. Expression and regulation of UDP-Glucuronosyltransferases from the UGT1A ans UGT2B families in mice with altered PXR. 8th European ISSX Meeting. 2002.
    125. Radominska-Pandya A. Independent regulation of 1A and 2B UGT expression and UGT2B7/PXR correlated expression in human livers. International Society for the study of Xenobiotics. 2002.
    126. Hydel J-M, Li X, Radominska-Pandya A. Lithocholic acid decreases expression of UGT2B7 in Caco2 cell through Farnesoid X receptor antagonist activity. 8th european ISSX Meeting. 2002.
    127. Radominska-Pandya A. Induction of UDP-Glucuronosyltransferases by Endogenous Compounds. International Society for the Study of Xenobiotics. 2002.
    128. Hydel J-M, Lu Y, Goyal A, Czernik P, Xie W, Lindblom T, Mackenzie P, Radominska-Pandya A. Alternative transcript-specific expression for human PXR correlates with the expression for human PXR correlates with the expression of UGT2B7 in human liver and intestine. International Society for the Study of Xenobiotics. 2002.
    129. Sonka J, Little J, Samokyszyn V, Radominska-Pandya A. Glucuronidation of arachidonic acid 20-HETE and prostagladin E2 by human hepatic and intestinal UDP-glucuronosyltransferases and recombinant UGT2B7. International Society for the Study of Xenibiotics. 2002.
    130. Radominska-Pandya A, Little JM, Czernik PJ. Human UDP-glucuronosyltransferase 2B7. Curr Drug Metab. 2001 Sep; 2(3):283-98. PMID: 11513331.
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    131. Jude AR, Little JM, Czernik PJ, Tephly TR, Grant DF, Radominska-Pandya A. Glucuronidation of linoleic acid diols by human microsomal and recombinant UDP-glucuronosyltransferases: identification of UGT2B7 as the major isoform involved. Arch Biochem Biophys. 2001 May 15; 389(2):176-86. PMID: 11339806.
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    132. Jude AR, Little JM, Bull AW, Podgorski I, Radominska-Pandya A. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. Drug Metab Dispos. 2001 May; 29(5):652-5. PMID: 11302930.
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    133. Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, Evans RM. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3375-80. PMID: 11248086; PMCID: PMC30661.
    134. Santin AD, Hermonat PL, Ravaggi A, Bellone S, Roman JJ, Smith CV, Pecorelli S, Radominska-Pandya A, Cannon MJ, Parham GP. Phenotypic and functional analysis of tumor-infiltrating lymphocytes compared with tumor-associated lymphocytes from ascitic fluid and peripheral blood lymphocytes in patients with advanced ovarian cancer. Gynecol Obstet Invest. 2001; 51(4):254-61. PMID: 11408737.
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    135. Radominska-Pandya A, Chen G, Samokyszyn VM, Little JM, Gall WE, Zawada G, Terrier N, Magdalou J, Czernik P. Application of photoaffinity labeling with [(3)H] all trans- and 9-cis-retinoic acids for characterization of cellular retinoic acid--binding proteins I and II. Protein Sci. 2001 Jan; 10(1):200-11. PMID: 11266607; PMCID: PMC2249844.
    136. Radominska-Pandya A, Czernik P, Stewart S, Xu J, Little J, Jude A. Glucuronidation of fatty acids and their oxidize derivatives by human UDO-glucuronosylttransferases. 6th International ISSX Meeting. 2001.
    137. Radominska-Pandya A, Czernik P, Stewart S, Xu J, Little J, Jude A. Glucuronidation of fatty acid and their oxidized derivatives by human UDP-glucuronosyltransferases. 6th International ISSX Meeting. 2001.
    138. Antonio L, Czernik P, Xu J, Little JM, Fourmel-Gigleux S, Magdalou J, Radominska-Pandya A. Glucuronidation of catechols in human gastrointestinal tract and recombinant UGTs. Experimental Biology 2001. 2001.
    139. Czernik P, Pokrovskaya lD, Radominska-Pandya A. Xth International workshop on Glucuronidation and the UDP-Glucuronosyltransferases. Harima Science. 2001.
    140. Radominska-Pandya A, Czernik P, Little JM, Wooldrige CE. nuclear UDP-glucuronosyltransferases. Harima Science. 2001.
    141. Radominska-Pandya A, Pokrovskaya l, Little J, Xu J, Czernik P. Human UGT2B7: Nuclear localization by immunofluorescence and immunogold labeling. Internation ISSX Meeting. 2001.
    142. Radominska-Pandya A, Pokrovskaya l, Little J, Xu J, Czernik P. Human UGT2B7:Nuclear localization by immunofluorescence and immunogold labeling. 6th International Meeting. 2001.
    143. Chen G, Rabjohn PA, York JL, Wooldridge C, Zhang D, Falany CN, Radominska-Pandya A. Carboxyl residues in the active site of human phenol sulfotransferase (SULT1A1). Biochemistry. 2000 Dec 26; 39(51):16000-7. PMID: 11123927.
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    144. Chen G, Radominska-Pandya A. Direct photoaffinity labeling of cellular retinoic acid-binding protein I (CRABP-I) with all-trans-retinoic acid: identification of amino acids in the ligand binding site. Biochemistry. 2000 Oct 17; 39(41):12568-74. PMID: 11027136.
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    145. Czernik PJ, Little JM, Barone GW, Raufman JP, Radominska-Pandya A. Glucuronidation of estrogens and retinoic acid and expression of UDP-glucuronosyltransferase 2B7 in human intestinal mucosa. Drug Metab Dispos. 2000 Oct; 28(10):1210-6. PMID: 10997942.
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    146. Jude AR, Little JM, Freeman JP, Evans JE, Radominska-Pandya A, Grant DF. Linoleic acid diols are novel substrates for human UDP-glucuronosyltransferases. Arch Biochem Biophys. 2000 Aug 15; 380(2):294-302. PMID: 10933884.
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    147. Radominska-Pandya A, Chen G, Czernik PJ, Little JM, Samokyszyn VM, Carter CA, Nowak Gd. Direct interaction of all-trans-retinoic acid with protein kinase C (PKC). Implications for PKC signaling and cancer therapy. J Biol Chem. 2000 Jul 21; 275(29):22324-30. PMID: 10748087.
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    148. Tessier DC, Dignard D, Zapun A, Radominska-Pandya A, Parodi AJ, Bergeron JJ, Thomas DY. Cloning and characterization of mammalian UDP-glucose glycoprotein: glucosyltransferase and the development of a specific substrate for this enzyme. Glycobiology. 2000 Apr; 10(4):403-12. PMID: 10764828.
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    149. Samokyszyn VM, Gall WE, Zawada G, Freyaldenhoven MA, Chen G, Mackenzie PI, Tephly TR, Radominska-Pandya A. 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. J Biol Chem. 2000 Mar 10; 275(10):6908-14. PMID: 10702251.
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    150. Radominska-Pandya A, Jude AR, Little JM, Bull AW, Podgorskin l. Unsaturaterd fatty acids and lipoxygenase-derived monohydroxylated derivattives are novel substrates for ER and nuclear envelop localized UDP-glucuronosyltransferases. 13th International Symposium on Microsomes and Drug Oxidation. 2000.
    151. Nowell G, Radominska-Pandya A. Role of PKC in Oxidant-Induced decreases in cellular functions. American Society of Biochemistry and molecular biology and the American Society for Pharmacology and Experiment Therapeutics Joint Meeting. 2000.
    152. Czernik PJ, Santin AD, Pokrovsakya ID, Xu J, Little JM, Radominska-Pandya A. Inhibitors of cell proliferation mediated by human UDP-glucuronosyltransferases 2B7(UGT2B7). Experimental Biology 2000. 2000.
    153. Radominska-Pandya A, Czernik PJ, Little JM, Jude AR, Tephly TR, Carter CA. Identification of the recombinant UDP-glucuronosyltransferase 2B7 in nuclear envelops. DMW/ISSX meeting. 2000.
    154. Czernik P, Pokrovskaya I, Radominska-Pandya A. constitutive expression of human UDP-glucuronosyltranseferases 2B7 neuyralizes the anti-proliferative effect of retinoic acod in cell culture. American Society for Biochemistry and MOlecular Biology and The American Society for Pharamology and Experimental Therapeutics joint Meeting. 2000.
    155. Radominska-Pandya A, Chen G, Czernik PJ, Little JM, Samokyszyn VM, Carter CA, Nowak G. Direct Interaction of all-trans-retinoic acid with protein kinase C. 2000 FASEB Summer Research Conference-Retinoids. 2000.
    156. Radominska-Pandya A, Chen G. Photoaffinity labeling of human Reecombinant Retinoid X Receptor with 9-cis-Retinoic acid. American Society for Biochemistry and Molecular biology and the American Society for Pharamacology and Experimental Therapeutics joint meeting. 2000.
    157. Radominska-Pandya A, Czernik PJ, Little JM, Battaglia E, Mackenzie PI. Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev. 1999 Nov; 31(4):817-99. PMID: 10575553.
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    158. Chen G, Battaglia E, Senay C, Falany CN, Radominska-Pandya A. Photoaffinity labeling probe for the substrate binding site of human phenol sulfotransferase (SULT1A1): 7-azido-4-methylcoumarin. Protein Sci. 1999 Oct; 8(10):2151-7. PMID: 10548061; PMCID: PMC2144153.
    159. Cheng Z, Radominska-Pandya A, Tephly TR. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. Drug Metab Dispos. 1999 Oct; 27(10):1165-70. PMID: 10497143.
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    160. Senay C, Battaglia E, Chen G, Breton R, Fournel-Gigleux S, Magdalou J, Radominska-Pandya A. Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin. Arch Biochem Biophys. 1999 Aug 01; 368(1):75-84. PMID: 10415114.
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    161. Gall WE, Zawada G, Mojarrabi B, Tephly TR, Green MD, Coffman BL, Mackenzie PI, Radominska-Pandya A. Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7. J Steroid Biochem Mol Biol. 1999 Jul-Aug; 70(1-3):101-8. PMID: 10529008.
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    162. Terrier N, Benoit E, Senay C, Lapicque F, Radominska-Pandya A, Magdalou J, Fournel-Gigleux S. Human and rat liver UDP-glucuronosyltransferases are targets of ketoprofen acylglucuronide. Mol Pharmacol. 1999 Jul; 56(1):226-34. PMID: 10385704.
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    163. Nowell SA, Massengill JS, Williams S, Radominska-Pandya A, Tephly TR, Cheng Z, Strassburg CP, Tukey RH, MacLeod SL, Lang NP, Kadlubar FF. Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4, 5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved. Carcinogenesis. 1999 Jun; 20(6):1107-14. PMID: 10357796.
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    164. Little JM, Lester R, Kuipers F, Vonk R, Mackenzie PI, Drake RR, Frame L, Radominska-Pandya A. Variability of human hepatic UDP-glucuronosyltransferase activity. Acta Biochim Pol. 1999; 46(2):351-63. PMID: 10547036.
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    165. Cheng Z, Radominska-Pandya A, Tephly TR. Cloning and Expression of three human intestinal UDP-glucuronosyltransferases(UGTs): 1A5, 1A8, and 1A10. Society of Toxicology. 1999.
    166. Radominska-Pandya A, Jude R, Little M, Bull AW, Evans JE, Grant DF. Mono- and Di-hydroxylated fatty acid derivatives are novel substrates for human microsomal and recombinant UDP-glucuronosyltransferases. 7th European ISSX Meeting. 1999.
    167. Radominska-Pandya A, Chen G, Samokyszyn VM, Gall W, Zawada G, Terrier N, Zhang DG, Czernik P, Ong DE. Retinoic acid glucuronide and 5,6-epoxy retinoic acid: Novel Ligands for Cellular Retinoic Acid Binding Proteins (CRABP I and II). ASBMB Satellite Meeting. 1999.
    168. Jude AR, Little M, Gall W, Evans JE, Grant DF, Radominska-Pandya A. Linoleic acid diols: Novel substrate for human liver UDP-glucuronosyltransferases. ASBMB Satellite Meeting. 1999.
    169. Czernik PC, Guo L, Radominska-Pandya A. Regulation of the Human UDP-glucuronosyltransferases 2B7. ASBMB Satellite Meeting. 1999.
    170. Terrier N, Fournel-Gigleux S, Benoit E, Lapicque F, Radominska-Pandya A, Magdalou J. UDP-glucuronosyltranseferases as target of acylglucuronides of drugs and endogenous compounds. 2nd European congress of Phamacology. 1999.
    171. Cheng Z, Radominska-Pandya A, Tephly TR. Studies on the substrate specificity of human intestinal UDP-glucuronosyltransferases 1A8 and 1A10. 1999; 27:1165 - 1170.
    172. Chen G, Radominska-Pandya A. Direct photoaffinity labeling of cellur retinoic acid and biniding protein I (CRABP l) with all-trans-retinoic acid: Identification of Amino acids in the Ligand Biniding site. 9th North American ISSX meeting. 1999.
    173. Terrier N, Fournel-Gigleux S, Benoit E, Lapicque F, Radominska-Pandya A. UDP-Glucuronosyltransferases as targets of acylglucuronides of drugs and endogenous compounds. 1999; 13 (S1):369s - .
    174. Radominska-Pandya A, Little JM, Pandya JT, Tephly TR, King CD, Barone GW, Raufman JP. UDP-glucuronosyltransferases in human intestinal mucosa. Biochim Biophys Acta. 1998 Nov 02; 1394(2-3):199-208. PMID: 9795217.
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    175. Cheng Z, Radominska-Pandya A, Tephly TR. Cloning and expression of human UDP-glucuronosyltransferase (UGT) 1A8. Arch Biochem Biophys. 1998 Aug 15; 356(2):301-5. PMID: 9705221.
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    176. Battaglia E, Terrier N, Mizeracka M, Senay C, Magdalou J, Fournel-Gigleux S, Radominska-Pandya A. Interaction of periodate-oxidized UDP-glucuronic acid with recombinant human liver UDP-glucuronosyltransferase 1A6. Drug Metab Dispos. 1998 Aug; 26(8):812-7. PMID: 9698297.
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    177. Battaglia E, Radominska-Pandya A. A functional role for histidyl residues of the UDP-glucuronic acid carrier in rat liver endoplasmic reticulum membranes. Biochemistry. 1998 Jan 06; 37(1):258-63. PMID: 9425046.
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    178. King CD, Assouline J, Radominska A, Tephly TR. The role and expression of UGT2B7 in the GI tract and human brain. Society of Toxicology. 1998.
    179. Terrer N, Fournel-Gigleux S, Magdalou J, Radominska A. Effect of acyl glucuronides of endogenous compounds on UDP-glucuronosyltransferases. 12th Annual Symposium on Microsomes and Drug Oxidations. 1998.
    180. Nowell SA, Lang NP, Radominska-Pandya A. Glucurodination of N-hydroxy-2-amino-1-methyl-6phenylimidazo{4,5-b}pyridine (N-OH-PhlP) by human intestinal microsomes. 5th International Meeting of the International Society for the Study of Xenobiotics. 1998.
    181. Chen GP, Falany CN, Radominska A. Fluorescent photoaffinity labeling of human phenol sulfotransferase by 7-azido-4-metnylcoumarin. 12th Annual Symposium on Microsomes and Drug Oxidations. 1998.
    182. Battaglia E, Senay C, Chen G, Nowell S, Fournel-Gigleux S, Magdalou J, Radominska-Pandya A. Identification of the binding site of the human recombinant UDP-glucuronosyltransferases UGT1A6 by photoaffinity labeling. 5th International meeting of the International Society for the Study of Xenobiotics. 1998.
    183. Battaglia E, Senay C, Chen G, Nowell S, Falany C, Fournel-Gigleux S, Magdalou J, Drake RR, Radominska-Pandya A. Photoaffinity labeling of the aglycon binding site of the human recombinant UDP-glucuronosyltransferase UGT1A6 and phenol sulfotransferase P-PST with 7-azido-4-methylcoumarin. 9th International Workshop on Glucuronidation and UDP-Glucuronosyltransferases. 1998.
    184. Radominska-Pandya A, Gall W, Raufman J-P. Glucuronidation of estrogens by human intestinal microsomes. 12th Annual Symposium on Microsomes. 1998.
    185. Radominska-Pandya A, Gall W, Chen G, Little JM, Samokyszyn V, Terrier N, Carter CA, Ong DE. Synthesis, biotransformation and biological effects of retinoic acid glucuronide. 9th International Workshop on glucuronidation and UDP-glucuronosyltransferases. 1998.
    186. Czernik P, Gall W, Little M, Strassburg CP, Tukey RH, Raufman J-P, Radominska-Pandya A. UDP-glucuronosyltransferase activity in human intestinal microsomes. 9th International Workshop on Glucuronidation and UDP-Glucuronosytransferases. 1998.
    187. Radominska-Pandya A, Gall W, Little JM, Samokyszyn V. Glucuronidation of retinoic acid and 4-OH-RA by human liver microsomes and recombinant UGT proteins. 12th Annual Symposium on Microsomes and Drug Oxidations. 1998.
    188. Chen GP, Falany CN, Radominska-Pandya A. Fluorescent photoaffinity labeling of the human phenol sulfotransferase P-PST by 7-azido-4-methylcoumarin. 5th International Meeting of the International Society for the Study of Xenobiotics. 1998.
    189. Chen GP, Falany CN, Radominska A. Sulfotransferases in human intestinal tract. 12th Annual Symposium on Microsomes and Drug Oxidations. 1998.
    190. Terrier N, Fournel-Gigleux S, Magdalou J, Lapicque F, Benoit E, Chen G, Gall W, Ong DE, Radominska-Pandya A. Interaction of acyl glucuronides of xenobiotics and endogenous compounds with UDP-glucuronosyltransferases and cellular proteins. 9th International Workshop on Glucuronidation and UDP-Glucuronosyltransferases. 1998.
    191. Radominska A, Little JM, Pandya JT, Raufman J-P, King KD, Tephly TR. Steroid glucuronidation in human intestine. Society of Toxicology. 1998.
    192. Senay C, Ouzzine M, Battaglia E, Pless D, Cano V, Burchell B, Radominska A, Magdalou J, Fournel-Gigleux S. Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6. 1997; 51:406 - 413.
    193. Little JM, Radominska A, Raufman J-P. Glucuronidation of bile acid and retinoids by the rat and human liver and intestinal microsomes. 97th Annual Meeting of the American Gastroenterology Association. 1997.
    194. Battaglia E, Nowell S, Drake RR, Magdalou J, Fournel-Gigleux S, Senay C, Radominska A. Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid. 1997; 25:406 - 411.
    195. Battaglia E, Radominska A. A Functional Role for Histidyl Residues of the UDP-GlucuronicAcid Carrier in Rat Endoplasmic Reticulum Membranes. 17th International Congress of Biochemistry and Molecular Biology and Annual Meeting of American Society for Biochemistry and Molecular Biology. 1997.
    196. Radominska A, Nowell S, Drake RR, Senay C, Magdalou J, Fournel-Gigleux S, Battaglia E. Characterization of UDP-glucuronic acid binding site of recombinant human liver UGT1*6 by the photoaffinity labeling and proteolytic mapping. 17th International Congress and Molecular Biology and Annual Meeting of American Society for Biochemistry and Molecular Biology. 1997.
    197. Little JM, Radominska A. Application of photoaffinity labeling with [11,12-3H]all-trans-retinoic acid to characterization of rat liver microsomal UDP-glucuronosyltransferase(s) with activity toward retinoic acid. 1997; 230:497 - 500.
    198. Little JM, Lehman PA, Nowell S, Samokyszyn V, Radominska A. Glucuronidation of all-trans-retinoic acid and 5,6-epoxy-all-trans-retinoic acid. Activation of rat liver microsomal UDP-glucuronosyltransferase activity by alamethicin. 1997; 25:5 - 11.
    199. Battaglia E, Terrier T, Nowell S, Mizeracka M, Magdalou J, Fournel-Gigleux S, Radominska A. Affinity labeling of a the human recomibinant UDP-glucuronosyltransferases UGT1*6 with UDP-glucuronic acid analogs. 11th International Symposium on Microsomes and Drug Oxidation. 1996.
    200. Little J, Lehman P, Nowell S, Radominska A. Characterization of retinoid glucuronidation by rat liver microsomes. 8th International Workshop on Glucuronidation and UDP-Glucuronosyltransferases. 1996.
    201. Battaglia E, Terrier N, Mizeracka M, Nowell S, Magdalou J, Fournel-Gigleux S, Radominska A. Affinity labeling of the human recombinant UDP-glucuronosyltransferases UGT*6 with an aldehyde derivative of UDP-glucuronic acid. 8th International Workshop on Glucuronidation and UDP-Glucuronosyltranseferases. 1996.
    202. Radominska A, Drake RR, Zhu X, Veronese ME, Little JM, Nowell S, McManus ME, Lester R, Falany CN. Photoaffinity labeling of human recombinant sulfotransferases with 2-azidoadenosine 3',5'-[5'-32P]bisphosphate. 1996; 271:3195 - 3199.
    203. Radominska A. Retinoid specific UDP-Glucuronosyltransferases. 11th International Symposium on Microsomes and Drug Oxidations. 1996.
    204. Battaglia E, Nowell S, Drake RR, Mizeracka M, Berg CL, Magdalou J, Fournel-Gigleux S, Gollan JL, Lester R, Radominska A. Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum. 1996; 1283:223 - 231.
    205. Radominska A, Drake R, Battaglia E, Falany CN. Proteolytic mapping of photolabeled sulfotransferases and UGT1*6 active site peptides by tricine-SDS-page. 8th International Workshop on Glucuronidation and UDP-glucuronosyltransferases. 1996.
    206. Battaglia E, Nowell S, Magdalou J, Radominska A. Characterization of high and low affinity components for transport of UDP-glucuronic acid in rat liver endoplasmic reticulum. ASBMB/ASIP/AAJ Joint Meeting. 1996.
    207. Battaglia E, Radominska A. UDP-glucuronic acid transport in rat liver endoplasmic reticulum: Kinetic analysis and inhibition studies. 8th International Workshop on Glucuronidation and UDP-Glucuronosyltransferases. 1996.
    208. Little JM, Drake RR, Vonk R, Kuipers F, Lester R, Radominska A. Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs. 1995; 273:1551 - 1559.
    209. Berg CL, Radominska A, Lester R, Gollan JL. Membrane translocation and regulation of uridine diphosphate-glucuronic acid uptake in rat liver microsomal vesicles. 1995; 108:183 - 192.
    210. Radominska A, Drake RR. Synthesis and uses of azido-substituted nucleoside diphosphate sugar photoaffinity analogs. 1994; 230:330 - 339.
    211. Radominska A, Paul P, Treat S, Towbin H, Pratt C, Little J, Magdalou J, Lester R, Drake R. Photoaffinity labeling for evaluation of uridinyl analogs as specific inhibitors of rat liver microsomal UDP-glucuronosyltransferases. 1994; 1205:336 - 345.
    212. Battaglia E, Pritchard M, Ouzzine M, Fournel-Gigleux S, Radominska A, Siest G, Magdalou J. Chemical modification of human UDP-glucuronosyltransferase UGT1*6 by diethyl pyrocarbonate: possible involvement of a histidine residue in the catalytic process. 1994; 309:266 - 272.
    213. Pilot T, Ouzzine M, Fournel-Gigleux S, Lafaurie C, Radominska A, Burchell B, Siest G, Magdalou J. Production and characterization of catalytically active human liver UDP-glucuronosyltransferase as a fusion protein in E coli. 7th International Workshop on Glucuronidation and the UDP-Glucuronosyltransferases. 1994.
    214. Radominska A, Drake RR. methods of Enzymology vol 30 pp 333-339. Synthesis and uses of azido-nucleotide diphosphate suger photoaffinityanalogs. 1994.
    215. Radominska A, Lester R. Application of photoaffinity probes for the Characterization of UDP-glucosyltransferases. 7th International Workshop on Glucuronidation and the UDP-Glucuronosyltransferasess. 1994.
    216. Radominska A, Berg C, Treat S, Little JM, Lester R, Gollan JL, Drake RR. Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs. 1994; 1195:63 - 70.
    217. Magdalou J, Battaglia E, Ouzzine M, Pilot T, Fournel-Gigleux S, Senay C, Siest G, Radominska A. A structure and reaction mechanism of human UDP-glucuronosyltransferases. 8th Symposium of the Protein Society. 1994.
    218. Radominska A, Little JM, Lester R, Mackenzie PI. Bile acid glucuronidation by rat liver microsomes and cDNA-expressed UDP-glucuronosyltransferases. 1994; 1205:75 - 82.
    219. Paul P, Lutz TM, Osborn C, Kyosseva S, Elbein AD, Towbin H, Radominska A, Drake RR. Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases. 1993; 268:12933 - 12938.
    220. Radominska A, Treat S, Little J. Bile acid metabolism and the pathophysiology of cholestasis. 1993; 13:219 - 234.
    221. Pillot T, Ouzzine M, Fournel-Gigleux S, Lafaurie C, Tebbi D, Treat S, Radominska A, Lester R, Siest G, Magdalou J. Determination of the human liver UDP-glucuronosyltransferase 2B4 domains involved in the binding of UDP-glucuronic acid using photoaffinity labeling of fusion proteins. 1993; 197:785 - 791.
    222. Radominska A, Treat S, Little J. Seminars in Liver Diseases. Bile and metabolism and the pathophysiology of cholestasis. 1993.
    223. Pillot T, Ouzzine M, Fournel-Gigleux S, Lafaurie C, Radominska A, Lester R, Drake R, Treat S, Siest G, Magdalou J. Purification and characterization of a catalytically active human liver UDP-glucuronosyltransferase expressed as a fusion protein in E. coli. 1993; 196:473 - 479.
    224. Radominska A, Little J, Pyrek JS, Drake RR, Igari Y, Fournel-Gigleux S, Magdalou J, Burchell B, Elbein AD, Siest G. A novel UDP-Glc-specific glucosyltransferase catalyzing the biosynthesis of 6-O-glucosides of bile acids in human liver microsomes. 1993; 268:15127 - 15135.
    225. Battaglia E, Pritchard M, Said M, Fournel-Gigleux S, Ouzzine M, Pilot T, Radominska A, Siset G, Magdalou J. inhibitors and characterization of the active site of UDP-glucuronosyltransferase UGT*6. 7th International Workshop on glucuronidation and the UDP-Glucuronyltransferases. 1993.
    226. Pillot T, Ouzzine M, Fournel-Gigleux S, Lafaurie C, Radominska A, Burchell B, Siest G, Magdalou J. Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4. 1993; 268:25636 - 25642.
    227. Yang EK, Radominska A, Winder BS, Dannenberg AJ. Dietary lipids coinduce xenobiotic metabolizing enzymes in rat liver. 1993; 1168:52 - 58.
    228. Radominska A, Drake RR, Lgari Y, Elbein AD, Lester R, Zimniak P. Transport of 5-azido-UDP-glucuronic acid into human and rat liver microsomes and photolabeling of UDP-glucuronosyltransferases. ASBMB/Biophysical Society. 1992.
    229. Hofmann AF, Sjovall J, Kurz G, Radominska A, Schteingart CD, Tint GS, Vlahcevic ZR, Setchell KD. A proposed nomenclature for bile acids. 1992; 33:599 - 604.
    230. Drake RR, Igari Y, Lester R, Elbein AD, Radominska A. Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucuronosyltransferases. 1992; 267:11360 - 11365.
    231. Radominska A, Little JM, Lester R, St Pyrek J. Hepatic metabolism of 3-oxoandrost-4-ene-17 beta-carboxylic acid in the adult rat: formation of carboxyl-linked glucuronides both in vivo and in vitro. 1992; 57:328 - 334.
    232. Radominska A, Lgari Y, Little JM, Drake RR, Zimniak P, Lester R. Biosynthesis of glucosides of 6-hydroxylated bile acid by UDP-sugar-dependent mechanism in human liver microsomes. American Gastroenterological Association for the Study of liver Diseases. 1992.
    233. Radominska A, Little JM, Drake RR, Lester R. Application of 5-azido-UDP-glucuronic acid for the characterization of human liver microsomal UDP-glucuronosyltransferase. American Association For The Study of Liver Diseases. 1992.
    234. Drake RR, Lgari Y, Elbein AD, Lester R, Radominska A. Active-site orientation of UDP-glucuronosyltransferases and GLC-P-Dol synthase in rat liver microsomes. ASBMB/Biophysical society. 1992.
    235. Zimniak P, Zigler SA, III, Radominska A, Bleew M, Wolters H, Kuipers F, Singhal S, Vonk R, Awasthi YC, Lester R. Photoaffinity Labeling and Partial purification of a transporting glutathione conjugate-dependent ATPase from canalicular rat liver plasma membranes. ASBMB/Biophysical Society. 1992.
    236. Radominska A, Lester R. Human liver UDP-glucuronosyltransferases 8th international Colloquium Biologie Prospectives:Drug Metabolizing Enzymes in man. 1992.
    237. Zimniak P, Ziller SA, Radominska A, Wolters H, Kuipers F, Sharma R, Vonk R, Awasthi YC, Lester R. Identification of an ATP-dependent glutathione conjugate transporter in canalicur plasma membranes from normal rats and rats with conjugated hyperbilirubinemia(GY mutants). 1991.
    238. Kozlowski M, Radominska A, Lester R, Zimniak P. Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes. 1991; 5:A1663 - .
    239. Lester R, Radomniska A, Zimniak P, Little JM. "Bile acid Glucuronidation in the Adult and Newborn". Falk Symposium. 1991.
    240. Radominska A, Drake RR, Elbein AD, Lester R, Zimniak P. 5-Azido-UDP-Glucuronic acid: A New Affinity Probe for UDP-Glucuronic Acid-Utilizing Proteins. 1991.
    241. Zimniak P, Ziller SA, Radominska A, Wolters H, Kuipers F, Shrama R, Singhal RR, Vonk R, Awasthi YC, Lester R. Identification of an anion-transport ATPase in normal GY rat liver canalicular Plasma membranes that catalyzes glutathione conjugate-dependent ATP hydrolysis. Conference on the Characterization of Membrane Transport Mechanism. 1991.
    242. Dannenberg A, Radominska A, Scarlata S, Zakim D. Effect of high pressure treatment on the properties of human liver microsomal UDP-glucuronosyltransferase. 1991.
    243. Kozlowski M, Radominska A, Lester R, Zimniak P. Isolation of UDP-glucuronosyltransferase clones using specific PCR-generated probes. 1991.
    244. Radominska A, Little LM, Lester R, Zimniak P. Biosynthesis and Metabolism of bile acid Carboxyl-linked glucuronides. Falk Symposium. 1991.
    245. Little JM, Pyrek JS, Radominska A, Shattuck KE, Lester R. Hepatic metabolism of short-chain bile acids. Inversion of the 3-hydroxyl group of isoetianic acid (3 beta-hydroxy-5 beta-androstane-17 beta-carboxylic acid) by the adult rat. 1991; 32:1949 - 1957.
    246. Zimniak P, Radominska A, Lester R, Waxman DJ. Cytochromes P450 involved in the 6-hydroxylation of the bile acids in rats and humans. International Congress of Biochemistry. 1991.
    247. Zimniak P, Ziller S, Radominska A, Blaauw M, Wolters H, Kuipers F, Singhal S, Vonk R, Awasthi YC, Lester R. Photoaffinity Labeling With 8-Azido-32p ATP of the ATP-dependent Glutathione conjugate transporter in canalicular plasma membranes from normal wistar and GY mutants rats. 1991.
    248. Oude Elferink RP, Ottenhoff R, Radominska A, Hofmann AF, Kuipers F, Jansen PL. Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions. 1991; 274 ( Pt 1):281 - 286.
    249. Zimniak P, Radominska A, Kuipers F, Awashi YC, Vonk R, Lester R. Mechanism of resistance of the neonate to experiment induction of choslestasis. Pediatric cholesteis Novel Approaches to treatment of cholestasis. 1991.
    250. Iscan M, Radominska A, Zimniak P, Radominska-pandya A, Waxman DL. Inhibition studies on rat liver lithocholic acid 6-hydroxylase. Proceedings. VIII International Symposium on Microsomes and Drug Oxidation. 1990.
    251. Radominska A, Zimniak P, Lester R. The detoxification of bile acids. Bile acids as Therapeutic Agents. 1990; 99-109.
    252. Zimniak P, Radominska A, Lester R. Hospital Practice. The pathogenesis of cholestasis. 1990.
    253. Radominska A, Zimniak P, Falany J, Iscan M, Falany CN. Bile acid hydroxylation by human liver microsomes and vaccine virus-expressed cytochrome P-450 hPCN1 and hPCN3. American Society for Biochemistry and Molecular Biology. 1990.
    254. Radominska A, Lehman P, Zimniak P, Lester R. Induction of carboxyl-linked glucuronide biosynthesis. Formation of carboxyl-linked glucuronide of lithocholic acid. Falk Symposium. 1990.
    255. Zimniak P, Radominska A, Lester R. Phase I and II biotransformation of bile acids. Hepatic Metibolism and Disposition of Endo- and Xenobiotics. 1990.
    256. Radominska A, Zimniak P, Falany J, Iscan M, Lester R, Waxman D. Bile acid hydroxylation by human liver microsomes and vaccinia-virus expressed cytochrome P-450 hPCN1 and hPCN3. 1990; 4:A1972 - .
    257. Holsztynska EJ, Holsztynski W, Radominska A, Kozlowski M, Zimniak P. UDP-glucuronosyltransferases (UDPGTs):Structural analysis of protein sequences. 3rd North American Meeting , International Society for the Study of Xenobiotics. 1990.
    258. Little JM, Zimniak P, Lester R, Radominska A. Biosynthesis of bile acid carboxyl-linked glucuronides by developing rat liver. 1990.
    259. Zimniak P, Holsztynska EJ, Radominska A, Iscan M, Lester R, Waxman DJ. Cytochromes P450 Involved in the bile acid hydroxylation and detoxification in: "Hepatic Metabolism and Disposition of Endo- and Xenobiotics". Falk Symposium. 1990.
    260. Shattuck K, Little JM, Radominska A, Zimniak P, Lester R. Biliary secretion and hepatic and hepatic metabolism of 6-hydroxy (6-OH) bile acids in rat. Annual Meeting of Pediatric Research. 1989.
    261. Shattuck K, Little JM, Radominska A, Zimniak P, Lester R. Bilary secretion of hyodeoxycholic acid (HDCA) in rat. Annual Meeting of the Southern Society for Pediatric Research. 1989.
    262. Radominska A, Comer KA, Zimniak P, Falany J, Iscan M, Falany CN. Human bile acid sulfotransferase. 1989.
    263. Little M, Shattuck KE, Radominska A, Zimniak P, Lester R. Biliary secretion and hepatic metabolism of 6-hydroxy bile acids in the rat. 1988.
    264. Kuipers F, Radominska A, Zimniak P, Havinga R, Vonk RJ, Lester R. Defective bile secretion of bile acid 3-0-glucuronides in rats with hereditary conjugated hyperbilirubinemia: implications for the mechanism of lithocholate-glucuronide induced cholestasis. In trends in Bile Acid Research. Falk Symposium 52. 1988.
    265. Radominska A, Zimniak P, Tephly TR, Lester R. Bile acid glucuronidation. Trends in bile acid research. 1988; 99-110.
    266. Kuipers F, Radominska A, Zimniak P, Van Dijk TH, Havinga R, Vonk RJ, Lester R. Reduction of biliary glutathione secretion by low doses of sulfated and glucuronidated lithocholic acids in rat. 1988.
    267. Radominska A, Zimniak P, Lester R. In vitro glucuronidation of conventional and 6-hydroxylated bile acids by the rat and human liver microsomes. Falk Symposium 52 16 ,. 1988.
    268. Radominska A, Zimniak P. Comparison of bile acid glucuronidation activity in various species; solubilzation of rabbit liver caboxyl-directed bile acid UDP-glucuronosyltransferase(UDP-GT). FASEB J, 2:A581. 1988.
    269. Zimniak P, Radominska A, Lester R, Holsztynska E, Waxman D. The detoxification of lithocholic acid. 1988.
    270. Holsztynska E, Waxman D, Zimniak P, Radominska A, Lester R. Cytochromes P-450 involved in the hydroxylation of Lithocholic acid. 1988.
    271. Kuipers F, Radominska A, Zimniak P, Havinga R, Vonk RJ, Lester R. Defective bile secretion of bile acid 3-0-glucuronides in rats with hereditary conjugated hyperbillrubinemia:implications for the mechanism of lithocholate-glucuronide induced cholestasis. 1988.
    272. Radominska A, Zimniak P, Lester R, Holsztynska E, Waxman D. The hydroxylation of bile acids by human liver microsomes. 1988.
    273. Shattuck KE, Little JM, Radominska A, Zimniak P, Lester R. Lithocholate glucuronide and cholestasis:a positive vicious cycle. 1988.
    274. Radomniska-Pyrek A, Lester R, Pyrek JSt. Formation of three types of glucuronides of 6-hydroxy bile acids by rat liver microsomes. Fed Proc 46:698,. 1987.
    275. Radominska-Pyrek A, Zimniak P, Tephly TR, Lester R. The glucuronidation of bile acids. Bile acid and the liver. 1987.
    276. Radominska-Pyrek A, Zimniak P, Irshad YM. Specificity and purification of human hepatic UDP-glucuronosyltransferases acting on monohydroxylated short-chain bile acids Hepatology 6:1171. 1986.
    277. Shattuck KE, Radominska-Pyrek A, Zimniak P, Lester R, Adcock EW, Answer MS. Metabolism and cholestatic potential of nor-lithocholic acid nor-lithocholate glucuronide and lithocholate glucuronide in the isolated perfused rat liver Gastroenterology 90:1767. 1986.
    278. Radominska-Pyrek A, Zimniak P, Irshaid YM, Lester R, Tephly TR. Glucuronidation of the 6 -hydroxylated bile acids, hyocholic and hyodeoxycholic acids by human liver microsomes Hepatology 6:1171. 1986.
    279. Radominska-Pyrek P, Shattuck KE, Zimniak P, Lester R, Pyrek JSt. Diglucuronide: a novel bile acid metabolite Fed:Proc 45:1886. 1986.
    280. Zimniak P, Radominska-Pyrek A, Little JM, Lester R, Pyrek JSt. Hepatic metabolism of 3-oxo-androst-4-ene-17-carboxylic acid Fed Proc 45:1886. 1986.
    281. Radominska-Pyrek A, Huynh T, Lester R, St Pyrek J. Preparation and characterization of 3-monohydroxylated bile acids of different side chain length and configuration at C-3. Novel approach to the synthesis of 24-norlithocholic acid. 1986; 27:102 - 113.
    282. Drake RR, Underwood LJ, Jones J, Battaglia E, Mao F, Rechtin TM, Cantu S, Anderson S, Radominska A, Moyer MP. AZT metabolism and toxicity: application of 5-azido-3'-azido-2',3'-dideoxyuridine monophosphate a photoaffinity analog of AZT-monophosphate. Eighth International Conference on Antiviral Research. 1985.
    283. Radominska-Pyrek A, Pyrek JSt, Golunski E, Lester R. Biosynthesis of monohydroxylated bile acid glucuronides fed Proc 44:659. Annual Meeting of the American Federation of American societies for Experimental Biology. 1985.
    284. Little JM, Pyrek JSt, Radomniska-Pyrek A, Denkins Y, Lester R. Lithocholate minus two: bisnor bile acid is secreted in bile Hepatology 3:857. 1983.
    285. Radominska-Pyrek A, Kraus-Friedmann N, Little JM, Denkins Y, Lester R. Glucagon stimulates hepatic Na+K+ATPase Fed Proc 41:1400. Annual FASEB Meeting. 1982.
    286. Kraus-Friedmann N, Hummel L, Radominska-Pyrek A, Little JM, Lester R. Glucagon stimulation of hepatic Na+, K+-ATPase. 1982; 44:173 - 180.
    287. Ohta A, Waggoner K, Radominska-Pyrek A, Dowhan W. Cloning of genes involved in membrane lipid synthesis: effects of amplification of phosphatidylglycerophosphate synthase in Escherichia coli. 1981; 147:552 - 562.
    288. Little JM, Radominska-Pyrek A, Friedmann-Karus N, Denkins Y, Lester R. Glucagon stimulates hepatic Na+K+ATPase Hepatology 1:538. 1981.
    289. Radominska-Pyrek A, Little JM, Denkins Y, Lester Y. An improved method for determination of Na+ K-ATPase activity in rat liver homogenates. Hepatology 1:538. 1981.
    290. Radominska-Pyrek A, Friedmann-Kraus N, Little JM, Lester R. Hormonal regulation of hepatic NA+K+ATPase Hepatology 1;538. Annual Meeting of the American Association for the Study of Liver Diseases. 1981.
    291. Strosznajder J, Radominska-Pyrek A, Lazarewicz J, Horrocks LA. Effects of adenine nucleotides, biogenic amines and oleic acid on synthesis of choline and ethanolamine glycerophospholipids in neuronal and glial cells from adult rabbit brain. 1980; 27:693 - 700.
    292. Korohoda W, Stanisz J, Stanisz A, Chojnacki T, Palamarczyk G, Radominska-Pyrek A. Induction of an attachment and spreading on glass of Ehrlich ascites tumour cells by alpha-saturated polyprenols. 1980; 21:239 - 243.
    293. Radominska-Pyrek A, Chojnacki T, Zulczyk W. Acyl esters of polyprenols: specificity of microsomal transacylase for polyprenols of different chain length and saturation. 1979; 26:125 - 134.
    294. Radominska-Pyrek A, Dabrowiecki Z, Horrocks LA. Synthesis and content of ether-linked glycerophospholipids in the harderian gland of rabbits. 1979; 574:248-257.
    295. Radominska-Pyrek A, Chojnacki T, Pyrek JS. Fully unsaturated decaprenol from bovine pituitary glands. 1979; 86:395 - 401.
    296. Strosznajder J, Radominska-Pyrek A, Horrocks LA. Choline and ethanolamine glycerophospholipid synthesis in isolated synaptosomes of rat brain. 1979; 574:48 - 56.
    297. Zimnik P, Pilarska M, Radominska-Pyrek A. solublization of microsomal phosphoethanolamine transferase. XI International Congress of Biochemistry. 1979; 372.
    298. Radominska-Pyrek A, Dabrowiecki Z, Horrocks LA. Inhibition of ethanolamine and choline phosphoglyceride synthesis by CMP. 12th FEBS Meeting. 1978; 3447.
    299. Chojnacki T, Mankowski T, Palamarczyk G, Pless DD, Radominska-Pyrek A. Comparison of polyprenol derivatives in yeast glycosyl transfer reaction. IXth International Symposium on Carbohydrate Biochemistry. 1978.
    300. Radominska-Pyrek A, Dabrowiecki Z, Horrocks LA. Inhibition of ethanolamine and choline brain phosphoglyceride synthesis by CMP. Second meeting of the European society for Neurochemistry. 1978; 542.
    301. Radominska-Pyrek A. Solubilization of microsomal phosphoethanolaminetransferase by octyl glucoside. 1978; 85:1074 - 1081.
    302. Radominska-Pyrek A, Chojnacki T. Microsomal synthesis of esterified polyprenols. 12th FEBS Meeting. 1978; 3445.
    303. Strosznajder J, Radominska-Pyrek A, Lazarewicz J, Horrocks LA. Synthesis in vitro of 1-alkyl-2-acyl- and 1,2-diacyl-sn-glycerophosphorylcholines and ethanolamines by neuronal, glial and synaptosomal fractions from adult rabbit brain. 1977; 25:363 - 370.
    304. Strosznajder J, Radominska-Pyrek A, Lazawica J, Horrocks LA. Regulation of 1-alkyl-2-acyl- and 12-diacul-sn-glycero-3-phosphorycholine and ethanolamine synthesis in the synaptosomal fraction from adult rat brain. XXth International Conference on the Biochemistry of Lipids. 1977; 123.
    305. Radominska-Pyrek A, Strosznajder J, Dabrowiecki Z, Goracci G, Chojnacki T, Horrocks LA. Enzymic synthesis of ether types of choline and ethanolamine phosphoglycerides by microsomal fractions from rat brain and liver. 1977; 18:53 - 58.
    306. Chojnacki T, Radominska-Pyrek A, Korzybski T. Gel filtration of ethanolaminephosphate and cholinephosphate cytidylytransferase. 6th FEBS Meeting. 1976; 276.
    307. Radominska-Pyrek A, Strosznajder J, Dabrowiecki Z, Chojnacki T, Horrocks LA. Effects of free fatty acids on the enzymic synthesis of diacyl and ether types of choline and ethanolamine phosphoglycerides. 1976; 17:657 - 662.
    308. Radominska-Pyrek A, Dabrowiecki Z, Chojnacki T, Horrocks LA. Biosynthesis of ether lipids in the microsomal fraction of the rabbit Harderian gland. VXIII International Conference on the Biochemistry of lipids. 1975; 24.
    309. Stosznajder J, Radominska-Pyrek A, Lazarewicz J, Horrocks LA. Synthesis of ether lipids by ethanolamine and cholinephosphotransferases from neuronal and glial cell fractions from rabbit brain. XVII International Conference on the Biochemistry of Lipids. 1975; 26.
    310. Radominska-Pyrek A, Strosznajder J, Dabrowiecki Z, Chojnacki T, Horrocks LA. The effect of the fatty acids on the synthesis of choline and ethanolamine phosphoglycerides. 9th FEBS Meeting. 1974; 361.
    311. Strosznajder J, Radominska-Pyrek A, Dabrowiecki Z, Dziduszko J. Qualitative and quantitative analysis of lipids from human cerebrospinal fluid under normal conditions and in pathology of CNS. VII International congress of Neuropathology. 1974; 286.
    312. Horrocks LA, Amato RD, Radominska-Pyrek A. Anabolic and catabolic pathways for 1-alkyl-2-acyl-sn- and 1-alkenyl-2-acyl-sn-glycero-3-phosphorylethanol-amines. International Conference on Biochemistry of Lipids. 1974; 69.
    313. Matysiak Z, Radominska-Pyrek A, Chojnacki T. The cytidine mechanism and methylation pathway in the formation of N-methylated ethanolamine phosphoglycerides in Neurospora crassa. 1974; 3:143 - 151.
    314. Radominska-Pyrek A, Pyrek JSt, Chojnacki T. The characteristics and function of long-chain pollprenolic compounds in N.Crassa. IX International Congress of Biochemistry. 1973; 403.
    315. Horrocks LA, Radominska-Pyrek A. Enzymic synthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-(32P)-phosphorylethanolamines by microsomes from rat brain. 1972; 22:190 - 192.
    316. Radominska-Pyrek A, Horrocks LA. Enzymic synthesis of 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamines by the CDP-ethanolamine: 1-radyl-2-acyl-sn-glycerol ethanolaminephosphotransferase from microsomal fraction of rat brain. 1972; 13:580 - 587.
    317. Radominska-Pyrek A, Chojnacki T, Korzybski T. On The biosynthesis of phospholipids and other phosphodiesters via the cytidine mechanism. International symposium on biochemistry and Histochemistry of Myelin and Demyelinization. 1970; 50.
    318. Radominska-Pyrek A, Chojnacki T. The biosynthesis of phospholipids in the myelin fraction of rat brain. II International Meeting of international society for Neurochemistry. 1970; 329.
    319. Radominska-Pyrek A. On the properties of ethanolaminephosphate cytidylyltransferases in animal tissues. 1969; 16:17 - 23.
    320. Radominska-Pyrek A, Matysiak Z, Chojnacki T. The biosynthesis of cytidine diphosphate esters in rat liver and Neurospora crassa. 1969; 16:357 - 363.
    321. Radominska-Pyrek A, Chojnacki T, Korzybski T. On the biosynthesis of phospholipids and other phosphodiesters via cytidine mechanism. 1969; 7:359 - 362.
    322. Chojnacki T, Radominska-Pyrek A, Korzybski T. The separation of cholinephosphate cytidylyltransferase from ethanolaminephosphate cytidylyltransferase of rat liver and brain by gel filtration on Sephadex G-200. 1967; 14:383 - 388.
    323. Chojnacki T, Radominska-Pyrek A, Korzybski T. On the features of cytosine ring required for the coenzymic function of cytidine nucleotides in biosynthesis of phospholipids. 1967; 14:151 - 156.
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