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Jeffrey Sawyer

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPathology, College of Medicine
DivisionPathology Clinical
Address218 Freeway Medical Tower
5800 W. 10th
Mail Slot # 834
Little Rock AR 72204
Phone501-526-8000
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentGenetics, College of Medicine


    Collapse Research Funds 
    Collapse principal investigator/co-principal investigator research activities
    CA81506/03     (SAWYER, JEFFREY)Feb 23, 2000 - Jan 31, 2005
    NIH/Nat. Cancer Institute
    DNA Hypomethylation and Cancer
    Role: Principal Investigator

    CA81506/02     (SAWYER, JEFFREY)Feb 23, 2000 - Jan 31, 2002
    NIH/Nat. Cancer Institute
    DNA Hypomethylation and Cancer
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Richardson SM, Dove JH, Beaty JH, Sheffer BW, Spence DD, Warner WC, Sawyer JR, Kelly DM. Flexible intramedullary nailing of femoral shaft fractures: closed versus open reduction. J Pediatr Orthop B. 2019 Oct 22. PMID: 31651747.
      View in: PubMed
    2. Hartline J, Nolan V, Kelly DM, Sheffer BW, Spence DD, Pereiras L, Warner WC, Sawyer JR. Operating Room Personnel Determine Efficiency of Pediatric Spinal Fusions for Scoliosis. Spine Deform. 2019 09; 7(5):702-708. PMID: 31495469.
      View in: PubMed
    3. Hung CW, Vitale MG, Samdani A, Matsumoto H, Smith JT, Sturm PF, Sponseller PD, Luhmann SJ, St Hilaire T, El-Hawary R, Sawyer JR. Outcomes of Primary and Conversion Magnetically Controlled Growth Rods Are Different at Two-Year Follow-up: Results of North American Release. Spine Deform. 2019 09; 7(5):829-835. PMID: 31495485.
      View in: PubMed
    4. Nielsen E, Andras LM, Hosseinzadeh P, Mignemi M, Sawyer JR, Flynn JM, Albanese S, Skaggs DL. Changes in Pediatric Spine Surgery Patterns Over the Last 10 Years Among ABOS Part II Candidates. Spine (Phila Pa 1976). 2019 Sep; 44(18):E1103-E1107. PMID: 31261266.
      View in: PubMed
    5. Roaten JD, Kelly DM, Yellin JL, Flynn JM, Cyr M, Garg S, Broom A, Andras LM, Sawyer JR. Pediatric Femoral Shaft Fractures: A Multicenter Review of the AAOS Clinical Practice Guidelines Before and After 2009. J Pediatr Orthop. 2019 Sep; 39(8):394-399. PMID: 31393292.
      View in: PubMed
    6. Sawyer JR, Tian E, Walker BA, Wardell C, Lukacs JL, Sammartino G, Bailey C, Schinke CD, Thanendrarajan S, Davies FE, Morgan GJ, Barlogie B, Zangari M, van Rhee F. An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome. Blood Cancer J. 2019 Aug 09; 9(8):62. PMID: 31399558.
      View in: PubMed
    7. Franklin DB, Hardaway AT, Sheffer BW, Spence DD, Kelly DM, Muhlbauer MS, Warner WC, Sawyer JR. The Role of Computed Tomography and Magnetic Resonance Imaging in the Diagnosis of Pediatric Thoracolumbar Compression Fractures. J Pediatr Orthop. 2019 Aug; 39(7):e520-e523. PMID: 30589678.
      View in: PubMed
    8. Glotzbecker M, Miller P, Vitale M, DeWitt L, Grzywna A, Sawyer J, Pahys J, Cahill P, Emans J. Hemoglobin Levels Pre- and Posttreatment as a Surrogate for Disease Severity in Early-Onset Scoliosis. Spine Deform. 2019 07; 7(4):641-646. PMID: 31202383.
      View in: PubMed
    9. Villarreal ED, Wrenn JO, Sheffer BW, Sawyer JR, Spence DD, Kelly DM. Do Patient-specific or Fracture-specific Factors Predict the Development of Acute Compartment Syndrome After Pediatric Tibial Shaft Fractures? J Pediatr Orthop. 2019 May 29. PMID: 31157755.
      View in: PubMed
    10. Roye BD, Campbell ML, Matsumoto H, Pahys JM, Welborn MC, Sawyer J, Fletcher ND, McIntosh AL, Sturm PF, Gomez JA, Roye DP, Lenke LG, Vitale MG. Establishing Consensus on the Best Practice Guidelines for Use of Halo Gravity Traction for Pediatric Spinal Deformity. J Pediatr Orthop. 2019 Apr 15. PMID: 30994582.
      View in: PubMed
    11. Sheffer BW, Villarreal ED, Ochsner MG, Sawyer JR, Spence DD, Kelly DM. Concurrent Ipsilateral Tibial Shaft and Distal Tibial Fractures in Pediatric Patients: Risk Factors, Frequency, and Risk of Missed Diagnosis. J Pediatr Orthop. 2019 Apr 08. PMID: 30969196.
      View in: PubMed
    12. Perchik JD, Murphy RP, Kelly DM, Sawyer JR. Radiation exposure in adult and pediatric patients with osteogenesis imperfecta. J Orthop. 2019 Jul-Aug; 16(4):320-324. PMID: 30976147.
      View in: PubMed
    13. Hosseinzadeh P, Obey MR, Nielsen E, Andras L, Kiebzak GM, Mignemi M, Sawyer JR, Albanese S, Flynn JM. Orthopaedic Care for Children: Who Provides It? How Has It Changed Over the Past Decade? Analysis of the Database of the American Board of Orthopaedic Surgery. J Pediatr Orthop. 2019 Mar; 39(3):e227-e231. PMID: 30358690.
      View in: PubMed
    14. Ashby C, Tytarenko RG, Wang Y, Weinhold N, Johnson SK, Bauer M, Wardell CP, Schinke C, Thanendrarajan S, Zangari M, van Rhee F, Davies FE, Sawyer JR, Morgan GJ, Walker BA. Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53. Oncotarget. 2019 Jan 22; 10(7):732-737. PMID: 30774775.
      View in: PubMed
    15. Obey MR, Lamplot J, Nielsen ED, Andras LM, Mignemi M, Sawyer J, Flynn JM, Albanese SA, Hosseinzadeh P. Pediatric Sports Medicine, A New Subspeciality in Orthopedics: An Analysis of the Surgical Volume of Candidates for the American Board of Orthopaedic Surgery Part II Certification Exam Over the Past Decade. J Pediatr Orthop. 2019 Jan; 39(1):e71-e76. PMID: 30363045.
      View in: PubMed
    16. Harris LR, Arkader A, Broom A, Flynn J, Yellin J, Whitlock P, Miller A, Sawyer J, Roaten J, Skaggs DL, Choi PD. Pulseless Supracondylar Humerus Fracture With Anterior Interosseous Nerve or Median Nerve Injury-An Absolute Indication for Open Reduction? J Pediatr Orthop. 2019 Jan; 39(1):e1-e7. PMID: 30080770.
      View in: PubMed
    17. Hosseinzadeh P, DeVries CA, Nielsen E, Andras LA, Mignemi M, Sawyer JR, Flynn JM, Albanese SA. Changes in the Practice of Pediatric Orthopaedic Surgeons Over the Past Decade: Analysis of the Database of the American Board of Orthopaedic Surgery. J Pediatr Orthop. 2018 Sep; 38(8):e486-e489. PMID: 29917007.
      View in: PubMed
    18. Mosher ZA, Sawyer JR, Kelly DM. MRI Safety with Orthopedic Implants. Orthop Clin North Am. 2018 Oct; 49(4):455-463. PMID: 30224007.
      View in: PubMed
    19. Rider CM, Hong VY, Westbrooks TJ, Wang J, Sheffer BW, Kelly DM, Spence DD, Flynn JM, Sawyer JR. Surgical Treatment of Supracondylar Humeral Fractures in a Freestanding Ambulatory Surgery Center is as Safe as and Faster and More Cost-Effective Than in a Children's Hospital. J Pediatr Orthop. 2018 Jul; 38(6):e343-e348. PMID: 29664879.
      View in: PubMed
    20. Kutsikovich JI, Hopkins CM, Gannon EW, Beaty JH, Warner WC, Sawyer JR, Spence DD, Kelly DM. Factors that predict instability in pediatric diaphyseal both-bone forearm fractures. J Pediatr Orthop B. 2018 Jul; 27(4):304-308. PMID: 28777160.
      View in: PubMed
    21. Ramirez N, Padilla J, Villarin S, Irizarry F, Iriarte I, Sawyer J. Impact of patient position on coronal Cobb angle measurement in non-ambulatory myelodysplastic patients. Eur J Orthop Surg Traumatol. 2019 Jan; 29(1):25-29. PMID: 29915954.
      View in: PubMed
    22. Feinberg N, Matsumoto H, Hung CW, St Hilaire T, Pawelek J, Sawyer JR, Akbarnia BA, Skaggs DL, Roye BD, Roye DP, Vitale MG. Expert Consensus and Equipoise: Planning a Randomized Controlled Trial of Magnetically Controlled Growing Rods. Spine Deform. 2018 May - Jun; 6(3):303-307. PMID: 29735141.
      View in: PubMed
    23. Hosseinzadeh P, Louer C, Sawyer J, Flynn J, Albanese S. Subspecialty Training Among Graduates of Pediatric Orthopaedic Fellowships: An 11-Year Analysis of the Database of American Board of Orthopaedic Surgery. J Pediatr Orthop. 2018 May/Jun; 38(5):293-296. PMID: 29509607.
      View in: PubMed
    24. Pharr ZK, Roaten JD, Moisan A, Kelly DM, Sawyer JR. Use of a Core Reamer for the Resection of a Central Distal Femoral Physeal Bone Bridge: A Novel Technique with 3-Year Follow-up. Am J Orthop (Belle Mead NJ). 2018 May; 47(5). PMID: 29883506.
      View in: PubMed
    25. Smith PJ, Hollins AM, Sawyer JR, Spence DD, Outlaw S, Kelly DM. Characterization of American Football Injuries in Children and Adolescents. J Pediatr Orthop. 2018 Feb; 38(2):e57-e60. PMID: 29189531.
      View in: PubMed
    26. McKelvey KD, Trana CJ, Kelsay J, Sawyer J, Clothier J. Phelan-McDermid syndrome and cancer predisposition: The value of a karyotype. Am J Med Genet A. 2018 01; 176(1):144-145. PMID: 29210508.
      View in: PubMed
    27. Sawyer JR, Morgan GJ. Hyperhaploid karyotypes in multiple myeloma. Oncotarget. 2017 Oct 03; 8(45):78259-78260. PMID: 29108224.
      View in: PubMed
    28. Sheffer BW, Kelly DM, Rhodes LN, Sawyer JR. Perioperative Pain Management in Pediatric Spine Surgery. Orthop Clin North Am. 2017 Oct; 48(4):481-486. PMID: 28870307.
      View in: PubMed
    29. Roaten JD, Kelly DM, Yellin JL, Flynn JM, Cyr M, Garg S, Broom A, Andras LM, Sawyer JR. Pediatric Femoral Shaft Fractures: A Multicenter Review of the AAOS Clinical Practice Guidelines Before and After 2009. J Pediatr Orthop. 2017 Apr 10. PMID: 28399048.
      View in: PubMed
    30. Jethava YS, Mitchell A, Epstein J, Zangari M, Yaccoby S, Tian E, Waheed S, Khan R, Papanikolaou X, Grazziutti M, Cottler-Fox M, Petty N, Steward D, Panozzo S, Bailey C, Hoering A, Crowley J, Sawyer J, Morgan G, Barlogie B, van Rhee F. Adverse Metaphase Cytogenetics Can Be Overcome by Adding Bortezomib and Thalidomide to Fractionated Melphalan Transplants. Clin Cancer Res. 2017 Jun 01; 23(11):2665-2672. PMID: 27810902.
      View in: PubMed
    31. Tian E, Børset M, Sawyer JR, Brede G, Våtsveen TK, Hov H, Waage A, Barlogie B, Shaughnessy JD, Epstein J, Sundan A. Allelic mutations in noncoding genomic sequences construct novel transcription factor binding sites that promote gene overexpression. Genes Chromosomes Cancer. 2015 Nov; 54(11):692-701. PMID: 26220195.
      View in: PubMed
    32. Sawyer JR, Tian E, Heuck CJ, Johann DJ, Epstein J, Swanson CM, Lukacs JL, Binz RL, Johnson M, Sammartino G, Zangari M, Davies FE, van Rhee F, Morgan GJ, Barlogie B. Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma. Blood. 2015 Jun 11; 125(24):3756-9. PMID: 25943786.
      View in: PubMed
    33. Tian E, Sawyer JR, Heuck CJ, Zhang Q, van Rhee F, Barlogie B, Epstein J. In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes. Genes Chromosomes Cancer. 2014 Jul; 53(7):549-57. PMID: 24638926.
      View in: PubMed
    34. Sawyer JR, Tian E, Heuck CJ, Epstein J, Johann DJ, Swanson CM, Lukacs JL, Johnson M, Binz R, Boast A, Sammartino G, Usmani S, Zangari M, Waheed S, van Rhee F, Barlogie B. Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease. Blood. 2014 Apr 17; 123(16):2504-12. PMID: 24497533.
      View in: PubMed
    35. Murphy RF, Beaty JH, Kelly DM, Sawyer JR, Warner WC. Implant Failure in Slipped Capital Femoral Epiphysis: A Report of Two Cases. JBJS Case Connect. 2013 Dec 24; 3(4 Suppl 8):e138-e6. PMID: 29252294.
      View in: PubMed
    36. Hall JM, Sawyer JR, Warner WC, Moisan A, Kelly DM. A Pulseless Extremity Following an Apparently Nondisplaced Proximal Humeral Physeal Fracture: A Case Report. JBJS Case Connect. 2013 Sep 11; 3(3 Suppl 7):e90-e4. PMID: 29252271.
      View in: PubMed
    37. Usmani SZ, Sawyer J, Rosenthal A, Cottler-Fox M, Epstein J, Yaccoby S, Sexton R, Hoering A, Singh Z, Heuck CJ, Waheed S, Chauhan N, Johann D, Abdallah AO, Muzaffar J, Petty N, Bailey C, Crowley J, van Rhee F, Barlogie B. Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma. Blood. 2013 Jun 06; 121(23):4753-7. PMID: 23603914.
      View in: PubMed
    38. Zhou Y, Zhang Q, Stephens O, Heuck CJ, Tian E, Sawyer JR, Cartron-Mizeracki MA, Qu P, Keller J, Epstein J, Barlogie B, Shaughnessy JD. Prediction of cytogenetic abnormalities with gene expression profiles. Blood. 2012 May 24; 119(21):e148-50. PMID: 22496154.
      View in: PubMed
    39. Sawyer JR, Tian E, Thomas E, Koller M, Stangeby C, Sammartino G, Goosen L, Swanson C, Binz RL, Barlogie B, Shaughnessy J. Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon. Br J Haematol. 2009 Nov; 147(4):484-94. PMID: 19744130.
      View in: PubMed
    40. Barlogie B, Tricot G, Haessler J, van Rhee F, Cottler-Fox M, Anaissie E, Waldron J, Pineda-Roman M, Thertulien R, Zangari M, Hollmig K, Mohiuddin A, Alsayed Y, Hoering A, Crowley J, Sawyer J. Cytogenetically defined myelodysplasia after melphalan-based autotransplantation for multiple myeloma linked to poor hematopoietic stem-cell mobilization: the Arkansas experience in more than 3,000 patients treated since 1989. Blood. 2008 Jan 01; 111(1):94-100. PMID: 17895401.
      View in: PubMed
    41. Shaughnessy JD, Zhan F, Burington BE, Huang Y, Colla S, Hanamura I, Stewart JP, Kordsmeier B, Randolph C, Williams DR, Xiao Y, Xu H, Epstein J, Anaissie E, Krishna SG, Cottler-Fox M, Hollmig K, Mohiuddin A, Pineda-Roman M, Tricot G, van Rhee F, Sawyer J, Alsayed Y, Walker R, Zangari M, Crowley J, Barlogie B. A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1. Blood. 2007 Mar 15; 109(6):2276-84. PMID: 17105813.
      View in: PubMed
    42. Zhan F, Huang Y, Colla S, Stewart JP, Hanamura I, Gupta S, Epstein J, Yaccoby S, Sawyer J, Burington B, Anaissie E, Hollmig K, Pineda-Roman M, Tricot G, van Rhee F, Walker R, Zangari M, Crowley J, Barlogie B, Shaughnessy JD. The molecular classification of multiple myeloma. Blood. 2006 Sep 15; 108(6):2020-8. PMID: 16728703.
      View in: PubMed
    43. Hanamura I, Stewart JP, Huang Y, Zhan F, Santra M, Sawyer JR, Hollmig K, Zangarri M, Pineda-Roman M, van Rhee F, Cavallo F, Burington B, Crowley J, Tricot G, Barlogie B, Shaughnessy JD. Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation. Blood. 2006 Sep 01; 108(5):1724-32. PMID: 16705089.
      View in: PubMed
    44. Bergsagel PL, Kuehl WM, Zhan F, Sawyer J, Barlogie B, Shaughnessy J. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood. 2005 Jul 01; 106(1):296-303. PMID: 15755896.
      View in: PubMed
    45. Sawyer JR, Tricot G, Mattox S, Jagannath S, Barlogie B. Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin. Blood. 1998 Mar 01; 91(5):1732-41. PMID: 9473240.
      View in: PubMed
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