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Alan Tackett

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
DivisionBiochem & Molecular Histone Epigenet
AddressB421G Biomedical Research I
325 S. Elm St.
Mail Slot # 516
Little Rock AR 72205
Phone501-686-8152
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentDermatology, College of Medicine

    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPathology, College of Medicine

    TitleProfessor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPediatrics, College of Medicine
    DivisionDevelopmental Nutrition


    Collapse Overview 
    Collapse overview
    My laboratory focuses on histone epigenetic mechanisms that regulate gene transcription and that are coupled to melanoma progression. We utilize a suite of techniques in our studies including proteomics of human biopsies, immunohistochemistry, cell culture, tumorigenicity assays, ChIPseq, biochemical and proteomic approaches for analyses of protein complexes, and cutting-edge mass spectrometry for the analysis of histone post-translational modifications. We have a unique environment that provides for discovery-based studies like proteomics as well as hypothesis-driven studies like those we perform in cell culture and with skin biopsies. In addition to our melanoma work, we develop new technologies for epigenetic studies such as tools for detection of in vivo protein interactions and quantitative assays for histone modifying proteins.


    Collapse Research Funds 
    Collapse research activities
    S10 OD026736     (MACKINTOSH, SAMUEL)Aug 1, 2019 - Jul 31, 2020
    NIH/Office of the Director
    Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer
    Role: Co-Investigator

    R01CA236209     (TACKETT, ALAN)Jun 15, 2019 - May 31, 2024
    NIH/NCI
    Identification of Druggable Targets to Complement Melanoma Therapy
    Role: Principal Investigator

    F31CA232464     (KOSS, BRIAN)Mar 1, 2019 - Feb 28, 2021
    NIH/National Institutes of Health
    Epigenetic regulation of metabolic stress pathways in melanoma infiltrating lymphocytes- Resubmission
    Role: Co-Investigator

    R01AG062254     (REIS, ROBERT)Sep 30, 2018 - May 31, 2023
    NIH/Nat. Inst. on Aging
    Inference of Common Pathways Underlying Neurodegeneration & Other Age-Progressive Diseases
    Role: Co-Investigator

    R01HD093461     (MACNICOL, ANGUS M)Sep 1, 2018 - Jun 30, 2023
    NIH/NICHD
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Investigator

    P20GM125503     (O'BRIEN, CHARLES A)Feb 16, 2018 - Jan 31, 2023
    NIH/NIGMS
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Co-Investigator

    P20GM121293     (ZYBAYLOV, BORIS)Jul 1, 2017 - Jun 30, 2022
    NIH/National Institutes of Health - Pass Through: Arkansas Children's Hospital
    Microbiome-Derived Therapeutic Targets for Chronic Kidney Disease - Continuation
    Role: Principal Investigator

    R35GM122601     (RANEY, KEVIN DOUGLAS)May 1, 2017 - Apr 30, 2022
    NIH/NIGMS
    Functions and Mechanisms of Helicases and G-Quadruplex Nucleic Acids
    Role: Co-Investigator

    R01GM118760     (TACKETT, ALAN)Mar 1, 2017 - Jan 31, 2021
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Johns Hopkins University
    Epigenetic profiling and enzymatic regulation of H3K23me3 during cellular differentiation
    Role: Principal Investigator

    R21DA041822     (TACKETT, ALAN JACKSON)Jul 1, 2016 - Jun 30, 2018
    NIH/NIDA
    Technology for Identification of Epiproteomes in Tissue Samples
    Role: Principal Investigator

    P20GM109005     (HAUER-JENSEN, MARTIN)Jun 24, 2015 - Mar 31, 2020
    NIH/NIGMS
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator

    R21ES025268     (TACKETT, ALAN JACKSON)Apr 8, 2015 - Mar 31, 2017
    NIH/NIEHS
    Identifying the Epigenetic Regulation of Arsenic Exposure
    Role: Principal Investigator

    R01DK102206     (BALDINI, GIULIA)Sep 15, 2014 - Aug 31, 2019
    NIH/NIDDK
    Lipid Stress and MC4R
    Role: Co-Investigator

    NCC 9-58 95     (BOERMA, MARJAN)Jun 1, 2014 - May 31, 2017
    National Space Biomedical Research Institute
    Center for Research on Cardiac and Vascular Effects of Space Radiation
    Role: Co-Investigator

    NCC9-58     (BOERMA, MARJAN)Jun 1, 2014 - May 31, 2017
    National Space Biomedical Research Institute
    Center for Research on Cardiac and Vascular Effects of Space Radiation
    Role: Co-Investigator

    R15ES022781     (AYKIN-BURNS, NUKHET)Sep 13, 2013 - Aug 31, 2016
    NIH/NIEHS
    Sirt3: A Key Player Against PCB-Induced Mitochondrial Injury
    Role: Co-Investigator

    R33CA173264     (TACKETT, ALAN JACKSON)Sep 1, 2013 - Aug 31, 2016
    NIH/NCI
    Development of MassSQUIRM to Quantitatively Measure Lysine Methylation
    Role: Principal Investigator

    R01GM106024     (TAVERNA, SEAN D.)Jul 1, 2013 - Apr 30, 2017
    NIH/NIGMS
    Using ChAP-MS to Study Macromolecular Chromatin Composition during Transcription
    Role: Co-Principal Investigator

    R01AR060823     (MORELLO, ROY)Sep 17, 2012 - Jul 31, 2017
    NIH/NIAMS
    Role of the Leprecan Genes in Skeletal Formation
    Role: Co-Investigator

    HHSO100201100045C     (HAUER-JENSEN, MARTIN)Sep 26, 2011 - Jun 30, 2017
    DHHS - Biomedical Advanced Research and Development Authority
    Advanced Development of SOM230 as a Radiation Mitigator
    Role: Co-Investigator

    P30RR031154     (TACKETT, ALAN)Sep 1, 2010 - May 31, 2015
    NIH/Nat. Center for Research Resources - Pass Through: University of Arkansas at Fayetteville
    NIH COBRE Center for Protein Structure and Function
    Role: Principal Investigator

    P20RR016460     (CORNETT, LAWRENCE E)Aug 31, 2009 - Sep 29, 2004
    NIH/NCRR
    Partnerships for Biomedical Research in Arkansas
    Role: Co-Investigator

    R01DK080424     (BALDINI, GIULIA)Jun 1, 2009 - May 31, 2014
    NIH/NIDDK
    Melanocortin-4 Receptor Traffic and Signaling
    Role: Co-Investigator

    R01DA025755     (TACKETT, ALAN JACKSON)Sep 20, 2008 - Jul 31, 2013
    NIH/NIDA
    Development of technology for high resolution epigenetic profiling of chromatin
    Role: Principal Investigator

    R01GM081766     (WAHLS, WAYNE P)Aug 10, 2007 - May 31, 2019
    NIH/NIGMS
    Biochemistry of recombination in meiosis
    Role: Co-Investigator

    R56DK076735     (DRANOFF, JONATHAN A)Dec 1, 2006 - Aug 31, 2016
    NIH/NIDDK
    Regulation of hepatic stellate cells by intracellular calcium
    Role: Co-Investigator

    F32GM066496     (TACKETT, ALAN JACKSON)Sep 1, 2002
    NIH/NIGMS
    Analysis of Proteins Involed in Genome Duplication
    Role: Principal Investigator

    P20GM103429     (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2020
    NIH/NIGMS
    Partnerships for Biomedical Research in Arkansas
    Role: Co-Investigator

    P01AG012411     (GRIFFIN, SUE TILTON)Aug 1, 1997 - May 31, 2021
    NIH/NIA
    Early Events in Alzheimer Pathogenesis
    Role: Co-Investigator

    R01HL050545     (WARE, JERRY)May 1, 1994 - Nov 30, 2007
    NIH/NHLBI
    Transgenic analysis of platelet receptor expression
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Storey AJ, Naceanceno KS, Lan RS, Washam CL, Orr LM, Mackintosh SG, Tackett AJ, Edmondson RD, Wang Z, Li HY, Frett B, Kendrick S, Byrum SD. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Mol Omics. 2020 Apr 29. PMID: 32347222.
      View in: PubMed
    2. Davis LE, Shalin SC, Tackett AJ. Utility of histone H3K27me3 and H4K20me as diagnostic indicators of melanoma. Melanoma Res. 2020 04; 30(2):159-165. PMID: 32142497.
      View in: PubMed
    3. Storey AJ, Hardman RE, Byrum SD, Mackintosh SG, Edmondson RD, Wahls WP, Tackett AJ, Lewis JA. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. J Proteome Res. 2020 Mar 06; 19(3):1183-1195. PMID: 32027144.
      View in: PubMed
    4. Trentzsch M, Nyamugenda E, Miles TK, Griffin H, Russell S, Koss B, Cooney KA, Phelan KD, Tackett AJ, Iyer S, Boysen G, Baldini G. Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum. Cell Death Discov. 2020; 6:8. PMID: 32123584.
      View in: PubMed
    5. Taylor EM, Koss B, Davis LE, Tackett AJ. Histone Modifications as Biomarkers for Immunotherapy. Methods Mol Biol. 2020; 2055:213-228. PMID: 31502154.
      View in: PubMed
    6. Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2019 12 17; 9(1):19276. PMID: 31848380.
      View in: PubMed
    7. Ramirez AM, Byrum SD, Beenken KE, Washam C, Edmondson RD, Mackintosh SG, Spencer HJ, Tackett AJ, Smeltzer MS. Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS Infect Dis. 2020 02 14; 6(2):237-249. PMID: 31722523.
      View in: PubMed
    8. Byrum SD, Washam CL, Tackett AJ, Garcia-Rill E, Bisagno V, Urbano FJ. Proteomic measures of gamma oscillations. Heliyon. 2019 Aug; 5(8):e02265. PMID: 31497668.
      View in: PubMed
    9. Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. Blood. 2019 10 03; 134(14):1176-1189. PMID: 31383640.
      View in: PubMed
    10. Davis LE, Shalin SC, Tackett AJ. Current state of melanoma diagnosis and treatment. Cancer Biol Ther. 2019; 20(11):1366-1379. PMID: 31366280.
      View in: PubMed
    11. Chiang TC, Koss B, Su LJ, Washam CL, Byrum SD, Storey A, Tackett AJ. Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth. Medicines (Basel). 2019 Jun 27; 6(3). PMID: 31252639.
      View in: PubMed
    12. Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Drew A, Sridharan V, Boerma M, Tackett AJ, Zawieja D, Willey JS, Delp M, Pecaut MJ. Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations. Sci Rep. 2019 06 03; 9(1):8215. PMID: 31160660.
      View in: PubMed
    13. Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem. 2019 07 12; 294(28):10969-10986. PMID: 31152063.
      View in: PubMed
    14. Lo S, Byrum SD, Tackett AJ, Parajuli N. Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage. Transplant Direct. 2019 Jun; 5(6):e454. PMID: 31723591.
      View in: PubMed
    15. Garcia-Rill E, Tackett AJ, Byrum SD, Lan RS, Mackintosh SG, Hyde JR, Bisagno V, Urbano FJ. Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus. Brain Sci. 2019 Mar 18; 9(3). PMID: 30889866.
      View in: PubMed
    16. West KL, Byrum SD, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ. Proteomic characterization of the arsenic response locus in S. cerevisiae. Epigenetics. 2019 02; 14(2):130-145. PMID: 30739529.
      View in: PubMed
    17. Zybailov BL, Glazko GV, Rahmatallah Y, Andreyev DS, McElroy T, Karaduta O, Byrum SD, Orr L, Tackett AJ, Mackintosh SG, Edmondson RD, Kieffer DA, Martin RJ, Adams SH, Vaziri ND, Arthur JM. Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats. PLoS One. 2019; 14(1):e0199274. PMID: 30699108.
      View in: PubMed
    18. Shields BD, Koss B, Taylor EM, Storey AJ, West KL, Byrum SD, Mackintosh SG, Edmondson R, Mahmoud F, Shalin SC, Tackett AJ. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer Res. 2019 03 15; 79(6):1113-1123. PMID: 30674537.
      View in: PubMed
    19. Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY. An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells. Biochem Pharmacol. 2019 02; 160:134-145. PMID: 30578766.
      View in: PubMed
    20. Storey AJ, Wang HP, Protacio RU, Davidson MK, Tackett AJ, Wahls WP. Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot. Epigenetics Chromatin. 2018 10 29; 11(1):64. PMID: 30373637.
      View in: PubMed
    21. Byrum SD, Loughran AJ, Beenken KE, Orr LM, Storey AJ, Mackintosh SG, Edmondson RD, Tackett AJ, Smeltzer MS. Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome. J Proteome Res. 2018 10 05; 17(10):3384-3395. PMID: 30209945.
      View in: PubMed
    22. Mao XW, Byrum S, Nishiyama NC, Pecaut MJ, Sridharan V, Boerma M, Tackett AJ, Shiba D, Shirakawa M, Takahashi S, Delp MD. Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis. Int J Mol Sci. 2018 Aug 28; 19(9). PMID: 30154332.
      View in: PubMed
    23. Kriss CL, Gregory-Lott E, Storey AJ, Tackett AJ, Wahls WP, Stevens SM. In Vivo Metabolic Tracing Demonstrates the Site-Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation. Alcohol Clin Exp Res. 2018 10; 42(10):1909-1923. PMID: 30030934.
      View in: PubMed
    24. Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463. PMID: 30070965.
      View in: PubMed
    25. Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D. Oxidation resistance 1 is a novel senolytic target. Aging Cell. 2018 08; 17(4):e12780. PMID: 29766639.
      View in: PubMed
    26. McSweeney JC, Hudson TJ, Prince L, Beneš H, Tackett AJ, Miller Robinson C, Koeppe R, Cornett LE. Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas. Adv Physiol Educ. 2018 Mar 01; 42(1):123-129. PMID: 29446316.
      View in: PubMed
    27. Holthoff ER, Byrum SD, Mackintosh SG, Kelly T, Tackett AJ, Quick CM, Post SR. Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1. Clin Proteomics. 2017; 14:40. PMID: 29225558.
      View in: PubMed
    28. Wang P, Byrum S, Fowler FC, Pal S, Tackett AJ, Tyler JK. Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break. Nucleic Acids Res. 2017 Nov 02; 45(19):10923-10940. PMID: 29036368.
      View in: PubMed
    29. Miousse IR, Pathak R, Garg S, Skinner CM, Melnyk S, Pavliv O, Hendrickson H, Landes RD, Lumen A, Tackett AJ, Deutz NEP, Hauer-Jensen M, Koturbash I. Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology. Genes Nutr. 2017; 12:22. PMID: 28904640.
      View in: PubMed
    30. Oliveira C, Gunderman L, Coles CA, Lochmann J, Parks M, Ballard E, Glazko G, Rahmatallah Y, Tackett AJ, Thomas DJ. 16S rRNA Gene-Based Metagenomic Analysis of Ozark Cave Bacteria. Diversity (Basel). 2017 Sep; 9(3). PMID: 29551950.
      View in: PubMed
    31. Kim Wiese A, Schluterman Burdine M, Turnage RH, Tackett AJ, Burdine LJ. DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes. PLoS One. 2017; 12(7):e0181608. PMID: 28750002.
      View in: PubMed
    32. Miousse IR, Chang J, Shao L, Pathak R, Nzabarushimana É, Kutanzi KR, Landes RD, Tackett AJ, Hauer-Jensen M, Zhou D, Koturbash I. Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation. Int J Mol Sci. 2017 Jul 04; 18(7). PMID: 28677663.
      View in: PubMed
    33. Firwana B, Avaritt N, Shields B, Ravilla R, Makhoul I, Hutchins L, Tackett AJ, Mahmoud F. Do checkpoint inhibitors rely on gut microbiota to fight cancer? J Oncol Pharm Pract. 2018 Sep; 24(6):468-472. PMID: 28625074.
      View in: PubMed
    34. Mahmoud F, Shields B, Makhoul I, Avaritt N, Wong HK, Hutchins LF, Shalin S, Tackett AJ. Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack. Cancer Biol Ther. 2017 Jul 03; 18(7):451-469. PMID: 28513269.
      View in: PubMed
    35. Shields BD, Mahmoud F, Taylor EM, Byrum SD, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh SG, Edmondson RD, Shalin S, Tackett AJ. Indicators of responsiveness to immune checkpoint inhibitors. Sci Rep. 2017 04 11; 7(1):807. PMID: 28400597.
      View in: PubMed
    36. Byrum SD, Burdine MS, Orr L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection. PLoS One. 2017; 12(3):e0174771. PMID: 28350824.
      View in: PubMed
    37. Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G. 1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice. Toxicology. 2017 03 01; 378:114-124. PMID: 28082109.
      View in: PubMed
    38. Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY). 2016 12 15; 8(12):3486-3497. PMID: 27992858.
      View in: PubMed
    39. Blair LP, Liu Z, Labitigan RL, Wu L, Zheng D, Xia Z, Pearson EL, Nazeer FI, Cao J, Lang SM, Rines RJ, Mackintosh SG, Moore CL, Li W, Tian B, Tackett AJ, Yan Q. KDM5 lysine demethylases are involved in maintenance of 3'UTR length. Sci Adv. 2016 Nov; 2(11):e1501662. PMID: 28138513.
      View in: PubMed
    40. Yale K, Tackett AJ, Neuman M, Bulley E, Chait BT, Wiley E. Phosphorylation-Dependent Targeting of Tetrahymena HP1 to Condensed Chromatin. mSphere. 2016 Jul-Aug; 1(4). PMID: 27579368.
      View in: PubMed
    41. Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS. Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus. Infect Immun. 2016 09; 84(9):2586-94. PMID: 27354444.
      View in: PubMed
    42. Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016 10; 15(5):924-39. PMID: 27448508.
      View in: PubMed
    43. Prior S, Miousse IR, Nzabarushimana E, Pathak R, Skinner C, Kutanzi KR, Allen AR, Raber J, Tackett AJ, Hauer-Jensen M, Nelson GA, Koturbash I. Densely ionizing radiation affects DNA methylation of selective LINE-1 elements. Environ Res. 2016 10; 150:470-481. PMID: 27419368.
      View in: PubMed
    44. Boerma M, Sridharan V, Mao XW, Nelson GA, Cheema AK, Koturbash I, Singh SP, Tackett AJ, Hauer-Jensen M. Effects of ionizing radiation on the heart. Mutat Res. 2016 Oct - Dec; 770(Pt B):319-327. PMID: 27919338.
      View in: PubMed
    45. Shields BD, Tackett AJ, Shalin SC. Proteomics and melanoma: a current perspective. Glob Dermatol. 2016 Aug; 3(4):366-370. PMID: 30214824.
      View in: PubMed
    46. Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 05 19; 62(4):558-71. PMID: 27132940.
      View in: PubMed
    47. Sengupta D, Tackett AJ. Proteomic Findings in Melanoma. J Proteomics Bioinform. 2016 Apr; 9(4). PMID: 27274624.
      View in: PubMed
    48. Heard ME, Besio R, Weis M, Rai J, Hudson DM, Dimori M, Zimmerman SM, Kamykowski JA, Hogue WR, Swain FL, Burdine MS, Mackintosh SG, Tackett AJ, Suva LJ, Eyre DR, Morello R. Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. PLoS Genet. 2016 Apr; 12(4):e1006002. PMID: 27119146.
      View in: PubMed
    49. Mahmoud F, Shields B, Makhoul I, Hutchins LF, Shalin SC, Tackett AJ. Role of EZH2 histone methyltrasferase in melanoma progression and metastasis. Cancer Biol Ther. 2016 06 02; 17(6):579-91. PMID: 27105109.
      View in: PubMed
    50. Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature. 2016 Apr 21; 532(7599):329-33. PMID: 27027282.
      View in: PubMed
    51. Ayyadevara S, Mercanti F, Wang X, Mackintosh SG, Tackett AJ, Prayaga SV, Romeo F, Shmookler Reis RJ, Mehta JL. Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles. Hypertension. 2016 May; 67(5):1006-13. PMID: 26975704.
      View in: PubMed
    52. Shields B, Shalin SC, Tackett AJ. Microscopes and Mass Spectrometers. J Proteomics Bioinform. 2016; 9(Suppl 10). PMID: 29910559.
      View in: PubMed
    53. Byrum SD, Burdine MS, Orr L, Moreland L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates. J Proteomics Bioinform. 2016; 9(Suppl 10). PMID: 26962295.
      View in: PubMed
    54. Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016 Mar; 15(3):765-75. PMID: 26621846.
      View in: PubMed
    55. Salinas E, Byrum SD, Moreland LE, Mackintosh SG, Tackett AJ, Forrest JC. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016 02 01; 90(3):1397-413. PMID: 26581985.
      View in: PubMed
    56. Haun RS, Quick CM, Siegel ER, Raju I, Mackintosh SG, Tackett AJ. Bioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkers. Cancer Biol Ther. 2015; 16(10):1557-65. PMID: 26176765.
      View in: PubMed
    57. Burdine LJ, Burdine MS, Moreland L, Fogel B, Orr LM, James J, Turnage RH, Tackett AJ. Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway. PLoS One. 2015; 10(6):e0127943. PMID: 26065416.
      View in: PubMed
    58. Sengupta D, Kannan A, Kern M, Moreno MA, Vural E, Stack B, Suen JY, Tackett AJ, Gao L. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. Epigenetics. 2015; 10(6):460-6. PMID: 25941994.
      View in: PubMed
    59. Gao J, Zybailov BL, Byrd AK, Griffin WC, Chib S, Mackintosh SG, Tackett AJ, Raney KD. Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA. Chem Commun (Camb). 2015 Apr 28; 51(33):7242-4. PMID: 25813861.
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    60. Byrum SD, Taverna SD, Tackett AJ. Purification of specific chromatin loci for proteomic analysis. Methods Mol Biol. 2015; 1228:83-92. PMID: 25311124.
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    61. Papazyan R, Voronina E, Chapman JR, Luperchio TR, Gilbert TM, Meier E, Mackintosh SG, Shabanowitz J, Tackett AJ, Reddy KL, Coyne RS, Hunt DF, Liu Y, Taverna SD. Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. Elife. 2014 Aug 26; 3:e02996. PMID: 25161194.
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    62. Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD. The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3. Mol Cell Proteomics. 2014 Nov; 13(11):2896-910. PMID: 25106422.
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    63. Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol Cell Proteomics. 2014 Nov; 13(11):2883-95. PMID: 25104842.
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    64. Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ. A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics. 2014 Sep; 9(9):1207-11. PMID: 25147920.
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    65. Udensi UK, Tackett AJ, Byrum S, Avaritt NL, Sengupta D, Moreland LW, Tchounwou PB, Isokpehi RD. Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide. J Proteomics Bioinform. 2014 Jul; 7(7):166-178. PMID: 25419056.
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    66. Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20; 9(6):1284-93. PMID: 24707965.
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    67. Zhu B, Zhang M, Byrum SD, Tackett AJ, Davie JK. TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells. Int J Cancer. 2014 Aug 15; 135(4):785-97. PMID: 24470334.
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    68. Haun RS, Fan CY, Mackintosh SG, Zhao H, Tackett AJ. CD109 Overexpression in Pancreatic Cancer Identified by Cell-Surface Glycoprotein Capture. J Proteomics Bioinform. 2014; Suppl 10:S10003. PMID: 25635161.
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    69. Shao Q, Byrum SD, Moreland LE, Mackintosh SG, Kannan A, Lin Z, Morgan M, Stack BC, Cornelius LA, Tackett AJ, Gao L. A Proteomic Study of Human Merkel Cell Carcinoma. J Proteomics Bioinform. 2013 Nov 25; 6:275-282. PMID: 25284964.
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    70. Hammond SL, Byrum SD, Namjoshi S, Graves HK, Dennehey BK, Tackett AJ, Tyler JK. Mitotic phosphorylation of histone H3 threonine 80. Cell Cycle. 2014; 13(3):440-52. PMID: 24275038.
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    71. Byrum SD, Taverna SD, Tackett AJ. Purification of a specific native genomic locus for proteomic analysis. Nucleic Acids Res. 2013 Nov; 41(20):e195. PMID: 24030711.
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    72. Washam CL, Byrum SD, Leitzel K, Ali SM, Tackett AJ, Gaddy D, Sundermann SE, Lipton A, Suva LJ. Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):972-83. PMID: 23462923.
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    73. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013; 6(3):43-50.
    74. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013 Mar 01; 6(3):43-50. PMID: 23976835.
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    75. Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem. 2013 Mar 29; 288(13):9408-17. PMID: 23408432.
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    76. Lolis AA, Londhe P, Beggs BC, Byrum SD, Tackett AJ, Davie JK. Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes. J Biol Chem. 2013 Mar 15; 288(11):7676-87. PMID: 23364797.
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    77. Ramanagoudr-Bhojappa R, Blair LP, Tackett AJ, Raney KD. Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein. Nucleic Acids Res. 2013 Jan; 41(2):1029-46. PMID: 23175612.
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    78. Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96. PMID: 23075270.
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    79. Suter MA, Chen A, Burdine MS, Choudhury M, Harris RA, Lane RH, Friedman JE, Grove KL, Tackett AJ, Aagaard KM. A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J. 2012 Dec; 26(12):5106-14. PMID: 22982377.
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    80. Byrum SD, Raman A, Taverna SD, Tackett AJ. ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Rep. 2012 Jul 26; 2(1):198-205. PMID: 22840409.
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    81. Avaritt NL, Owens R, Larson SK, Reynolds M, Byrum S, Hiatt KM, Smoller BR, Tackett AJ, Cheung WL. Misregulation of Rad50 expression in melanoma cells. J Cutan Pathol. 2012 Jul; 39(7):680-684. PMID: 22725639.
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    82. Blair LP, Avaritt NL, Tackett AJ. Application of MassSQUIRM for quantitative measurements of lysine demethylase activity. J Vis Exp. 2012 Mar 11; (61). PMID: 22433969.
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    83. Byrum SD, Washam CL, Montgomery CO, Tackett AJ, Suva LJ. Proteomic technologies for the study of osteosarcoma. Sarcoma. 2012; 2012:169416. PMID: 22550414.
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    84. Arumugam K, MacNicol MC, Wang Y, Cragle CE, Tackett AJ, Hardy LL, MacNicol AM. Ringo/cyclin-dependent kinase and mitogen-activated protein kinase signaling pathways regulate the activity of the cell fate determinant Musashi to promote cell cycle re-entry in Xenopus oocytes. J Biol Chem. 2012 Mar 23; 287(13):10639-49. PMID: 22215682.
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    85. Byrum S, Smart SK, Larson S, Tackett AJ. Analysis of stable and transient protein-protein interactions. Methods Mol Biol. 2012; 833:143-52. PMID: 22183593.
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    86. Byrum S, Avaritt NL, Mackintosh SG, Munkberg JM, Badgwell BD, Cheung WL, Tackett AJ. A quantitative proteomic analysis of FFPE melanoma. J Cutan Pathol. 2011 Nov; 38(11):933-6. PMID: 21883366.
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    87. Byrum SD, Taverna SD, Tackett AJ. Quantitative analysis of histone exchange for transcriptionally active chromatin. J Clin Bioinforma. 2011 Jul 07; 1(1):17. PMID: 21884633.
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    88. Blair LP, Avaritt NL, Huang R, Cole PA, Taverna SD, Tackett AJ. MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity. Epigenetics. 2011 Apr; 6(4):490-9. PMID: 21273814.
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    89. Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ. Analysis of Histone Exchange during Chromatin Purification. J Integr OMICS. 2011; 1(1):61-5.
    90. Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ. Analysis of Histone Exchange during Chromatin Purification. J Integr OMICS. 2011 Feb 01; 1(1):61-65. PMID: 21709819.
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    91. Sekedat MD, Fenyö D, Rogers RS, Tackett AJ, Aitchison JD, Chait BT. GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol. 2010; 6:353. PMID: 20212525.
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    92. Elbein AD, Pastuszak I, Tackett AJ, Wilson T, Pan YT. Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen. J Biol Chem. 2010 Mar 26; 285(13):9803-12. PMID: 20118231.
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    93. Smart SK, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ. Mapping the local protein interactome of the NuA3 histone acetyltransferase. Protein Sci. 2009 Sep; 18(9):1987-97. PMID: 19621382.
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    94. Gradolatto A, Smart SK, Byrum S, Blair LP, Rogers RS, Kolar EA, Lavender H, Larson SK, Aitchison JD, Taverna SD, Tackett AJ. A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. Mol Cell Biol. 2009 Sep; 29(17):4604-11. PMID: 19581291.
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    95. Blair LP, Tackett AJ, Raney KD. Development and evaluation of a structural model for SF1B helicase Dda. Biochemistry. 2009 Mar 24; 48(11):2321-9. PMID: 19256528.
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    96. Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD. NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations*S?. J Biol Chem. 2009; 284(8):4806-14.
    97. Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD. NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. J Biol Chem. 2009 Feb 20; 284(8):4806-14. PMID: 19088075.
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    98. Upreti M, Galitovskaya EN, Chu R, Tackett AJ, Terrano DT, Granell S, Chambers TC. Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. J Biol Chem. 2008 Dec 19; 283(51):35517-25. PMID: 18974096.
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    99. Gradolatto A, Rogers RS, Lavender H, Taverna SD, Allis CD, Aitchison JD, Tackett AJ. Saccharomyces cerevisiae Yta7 regulates histone gene expression. Genetics. 2008 May; 179(1):291-304. PMID: 18493054.
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    100. Sikora B, Chen Y, Lichti CF, Harrison MK, Jennings TA, Tang Y, Tackett AJ, Jordan JB, Sakon J, Cameron CE, Raney KD. Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activity in Vitro*S?. J Biol Chem. 2008; 283(17):11516-25.
    101. Hatcher R, Beck M, Tackett A, Pantelides ST. Dynamical effects in the interaction of ion beams with solids. Phys Rev Lett. 2008 Mar 14; 100(10):103201. PMID: 18352184.
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    102. Sikora B, Chen Y, Lichti CF, Harrison MK, Jennings TA, Tang Y, Tackett AJ, Jordan JB, Sakon J, Cameron CE, Raney KD. Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem. 2008 Apr 25; 283(17):11516-25. PMID: 18283103.
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    103. Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. J Proteome Res. 2008 Mar; 7(3):1244-50. PMID: 18271525.
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    104. Upreti, M, Galitovskaya, EN, Chu, R, Tackett AJ, Granell, S, Chambers, TC. Direct biochemical identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. 2008.
    105. Taverna SD, Ueberheide BM, Liu Y, Tackett AJ, Diaz RL, Shabanowitz J, Chait BT, Hunt DF, Allis CD. Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2086-91. PMID: 17284592.
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    106. Taverna SD, Ilin S, Rogers RS, Tanny JC, Lavender H, Li H, Baker L, Boyle J, Blair LP, Chait BT, Patel DJ, Aitchison JD, Tackett AJ, Allis CD. Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell. 2006 Dec 08; 24(5):785-796. PMID: 17157260.
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    107. Collom SL, Jamakhandi AP, Tackett AJ, Radominska-Pandya A, Miller GP. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling. Arch Biochem Biophys. 2007 Mar 01; 459(1):59-69. PMID: 17222385.
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    108. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature. 2006 Jul 06; 442(7098):86-90. PMID: 16728976.
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    109. Guermah M, Palhan VB, Tackett AJ, Chait BT, Roeder RG. Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell. 2006 Apr 21; 125(2):275-86. PMID: 16630816.
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    110. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodeling. Nature. 2006; 442:86-90.
    111. Taverna SD, Ilin S, Rogers RS, Tanny JC, Lavender H, Li H, Baker L, Boyle J, Blair LP, Chait BT, Patel DJ, Aitchison JD, Tackett A J (corresponding), Allis C D. Yng 1 PHD finger binding to histone H3 trimethylated at lysine 4 promotes NuA3 HAT activity at lysine 14 of H3 and transcriptional at a subset of targeted ORFs. Mol. Cell. 2006; 24:785-796.
    112. Dilworth DJ, Tackett AJ, Rogers RS, Yi EC, Christmas RH, Smith JJ, Siegel AF, Chait BT, Wozniak RW, Aitchison JD. The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol. 2005 Dec 19; 171(6):955-65. PMID: 16365162.
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    113. Tackett AJ, DeGrasse JA, Sekedat MD, Oeffinger M, Rout MP, Chait BT. I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions. J Proteome Res. 2005 Sep-Oct; 4(5):1752-6. PMID: 16212429.
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    114. Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 2005 Jun 17; 121(6):873-85. PMID: 15960975.
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    115. Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell M, Aitchison JD, Rout MP, Chait BT. Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol. 2005 Apr 11; 169(1):35-47. PMID: 15824130.
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    116. Tackett AJ, Chen Y, Cameron CE, Raney KD. Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro. J Biol Chem. 2005 Mar 18; 280(11):10797-806. PMID: 15634684.
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    117. Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell MD, Aitchison JD, Rout MP, Chait BT. Proteomic and genomic characterization of chromatin complexes at boundary. J. Cell. Biol. 2005; 169:35-47.
    118. Tackett AJ, DeGrasse JA, Oeffinger M, Rout MP. IDIRT, A General Method for Distinguished Between Specific and Non Specific Protein Interactions. J.Proteome. Res. 2005; 4:1752-6.
    119. Archambault V, Li CX, Tackett AJ, Wasch R, Chait BT, Rout MP, Cross FR. Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic ExitD?. Mol Biol Cell. 2003; 14(11):4592-604.
    120. Archambault V, Li CX, Tackett AJ, Wasch R, Chait BT, Rout MP, Cross FR. Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exit. Mol Biol Cell. 2003 Nov; 14(11):4592-604. PMID: 12960422.
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    121. Nanduri B, Byrd AK, Eoff RL, Tackett AJ, Raney KD. Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14722-7. PMID: 12411580.
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    122. Morris PD, Byrd AK, Tackett AJ, Cameron CE, Tanega P, Ott R, Fanning E, Raney KD. Hepatitis C virus NS3 and simian virus 40 T antigen helicases displace streptavidin from 5'-biotinylated oligonucleotides but not from 3'-biotinylated oligonucleotides: evidence for directional bias in translocation on single-stranded DNA. Biochemistry. 2002 Feb 19; 41(7):2372-8. PMID: 11841230.
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    123. Tackett AJ, Corey DR, Raney KD. Non-Watson-Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase. Nucleic Acids Res. 2002 Feb 15; 30(4):950-7. PMID: 11842106.
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    124. Tackett AJ, Corey DR, Raney KD. Non-Waston-Crick Interactions between PNA and DNA Inhibits the ATPase Activity of Bacteirophage. Nucleic Acids Res. 2002; 30:950-957.
    125. Morris PD, Byrd AK, Tackett AJ, Cameron CE, Tanega P, Ott R, Fanning E, Raney KD. Hepatitis C Virus NS3 and simian Virus 40 T Antigen Helicases Displace Streptavidin from 5-Biotinylated Oligonucleotides but not from 3-Biotinylated Oligonnucleotides: evidence for directional Bias in Translocation on Single- Stranded DNA. Biochemistry. 2002; 41:2372-2378.
    126. Morris PD, Tackett AJ, Babb K, Nanduri B, Chick C, Scott J, Raney KD. Evidence for a functional Monomeric Form of the Bacteriophage T4 Dda Helicase. J Bio Chem. 2001; 276:19691-19698.
    127. Avaritt NL, Fade M, Reynolds M, Sengupta D, Makhoul I, Shalin S, Tackett AJ. Cutaneous Melanoma: Molecular Mechanisms and Current Therapeutic Approaches.
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