Header Logo
Keywords
Last Name
Institution
Announcement

You can now add alternative names! Click here to add other names that you've published under.

Alan Tackett

TitleDistinguished Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentBiochemistry & Molecular Biology, College of Medicine
AddressB421G Biomedical Research I
325 S. Elm St.
Mail Slot # 803
Little Rock AR 72205
Phone501-686-8152
vCardDownload vCard
    Other Positions
    TitleDistinguished Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentDermatology, College of Medicine

    TitleDistinguished Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPathology, College of Medicine

    TitleDistinguished Professor
    InstitutionUniversity of Arkansas for Medical Sciences
    DepartmentPediatrics, College of Medicine
    DivisionDevelopmental Nutrition


    Collapse Overview 
    Collapse overview
    My laboratory focuses on histone epigenetic mechanisms that regulate gene transcription and that are coupled to melanoma progression. We utilize a suite of techniques in our studies including proteomics of human biopsies, immunohistochemistry, cell culture, tumorigenicity assays, ChIPseq, biochemical and proteomic approaches for analyses of protein complexes, and cutting-edge mass spectrometry for the analysis of histone post-translational modifications. We have a unique environment that provides for discovery-based studies like proteomics as well as hypothesis-driven studies like those we perform in cell culture and with skin biopsies. In addition to our melanoma work, we develop new technologies for epigenetic studies such as tools for detection of in vivo protein interactions and quantitative assays for histone modifying proteins.


    Collapse Research 
    Collapse research activities and funding
    P20GM152281     (MACNICOL, ANGUS)Mar 5, 2024 - Dec 31, 2028
    NIH/Nat. Inst. of General Medical Sciences
    Center for Molecular Interactions in Cancer (CMIC)
    Role: Principal Investigator
    P20GM125503     (OBRIEN, CHARLES A)Apr 1, 2023 - Jan 31, 2028
    NIH/Nat. Inst. of General Medical Sciences
    Center for Musculoskeletal Disease Research (CMDR)
    Role: Co-Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2024
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Principal Investigator
    R01GM141040     (LUPU, FLOREA)Sep 10, 2021 - Aug 31, 2025
    NIH
    Discovery and Characterization of Novel Sepsis Proteome Biomarkers
    Role: Co-Principal Investigator
    W81XWH2110460     (CANNON, MARTIN)Jul 1, 2021 - Jun 30, 2024
    US Department of Defense
    Proteogenomic analysis of responders versus nonresponders in a Phase I clinical trial of Th17-inducing dendritic cell vaccination for advanced stage ovarian cancer
    Role: Principal Investigator
    P20GM139768     (TACKETT, ALAN J)Apr 1, 2021 - Feb 28, 2026
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: University of Arkansas at Fayetteville
    Arkansas Integrative Metabolic Research Center
    Role: Principal Investigator
    R24 GM137786-02S2     (TACKETT, ALAN J)Aug 20, 2020 - May 31, 2025
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: NIH/Nat. Inst. of General Medical Sciences
    IDeA National Resource for Quantitative Proteomics
    Role: Principal Investigator
    R24GM137786     (TACKETT, ALAN)Aug 20, 2020 - May 31, 2025
    NIH
    IDeA National Resource for Quantitative Proteomics
    Role: Principal Investigator
    S10 OD026736     (MACKINTOSH, SAMUEL)Aug 1, 2019 - Jul 31, 2020
    NIH/Office of the Director
    Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer
    Role: Co-Investigator
    S10OD026736     (MACKINTOSH, SAMUEL G.)Aug 1, 2019 - Jul 31, 2020
    NIH
    Q Exactive HF-X Hybrid Quadrupole Orbitrap Mass Spectrometer
    Role: Co-Investigator
    R01CA236209     (TACKETT, ALAN)Jun 15, 2019 - May 31, 2024
    NIH
    Identification of Druggable Targets to Complement Melanoma Therapy
    Role: Principal Investigator
    F31CA232464     (KOSS, BRIAN)Mar 1, 2019 - Feb 28, 2022
    NIH
    Epigenetic regulation of metabolic stress pathways in melanoma infiltrating lymphocytes- Resubmission
    Role: Co-Investigator
    ABCRP FY19     (EOFF, ROBERT L)Feb 1, 2019 - Jun 30, 2021
    UAMS Executive Breast Committee
    No FP attached
    Role: Principal Investigator
    ABCRPFY19     (EOFF, ROBERT L)Feb 1, 2019 - Jun 30, 2021
    UAMS Executive Breast Committee
    No FP attached
    Role: Principal Investigator
    R01AG062254     (REIS, ROBERT)Sep 30, 2018 - May 31, 2023
    NIH/Nat. Inst. on Aging
    Inference of Common Pathways Underlying Neurodegeneration & Other Age-Progressive Diseases
    Role: Co-Investigator
    R01HD093461     (CHILDS, GWEN V;MACNICOL, ANGUS M ;MACNICOL, MELANIE C)Sep 1, 2018 - Jun 30, 2024
    NIH
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Investigator
    R56AG056372     (ZHENG, GUANGRONG)Sep 30, 2017 - Aug 31, 2019
    NIH
    Discovery and Target Identification of Senolytic Agents
    Role: Principal Investigator
    ACRI # 034478     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034485     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034487     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034507     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034508     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 034518     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034476     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034477     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034479     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034485     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034517     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034527     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034537     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #034665     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    ACRI Genomics CORE
    Role: Principal Investigator
    ACRI 034528     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI# 034538     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034476     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034477     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034478     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034479     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034485     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034487     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034507     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034508     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034517     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034518     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034527     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034537     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034538     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#034665     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    ACRI Genomics CORE
    Role: Principal Investigator
    ACRI034528     (TACKETT, ALAN J)Jul 11, 2017 - Jun 30, 2022
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #039437     (TACKETT, ALAN J)Jun 6, 2017 - May 30, 2018
    UAMS ACHRI Flow Through
    ACRI Tackett Lab Flowthrough
    Role: Principal Investigator
    ACRI#039437     (TACKETT, ALAN J)Jun 6, 2017 - May 30, 2018
    UAMS ACHRI Flow Through
    ACRI Tackett Lab Flowthrough
    Role: Principal Investigator
    R35GM122601     (RANEY, KEVIN DOUGLAS)May 1, 2017 - Apr 30, 2022
    NIH
    Functions and Mechanisms of Helicases and G-Quadruplex Nucleic Acids
    Role: Co-Investigator
    R01GM118760     (TACKETT, ALAN)Mar 1, 2017 - Jan 31, 2022
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Johns Hopkins University
    Epigenetic profiling and enzymatic regulation of H3K23me3 during cellular differentiation
    Role: Principal Investigator
    ACRI # 037077     (TACKETT, ALAN J)Feb 1, 2017 - Jul 30, 2017
    UAMS ACHRI Flow Through
    N. Avaritt ACHRI Staff – QuickStrike
    Role: Principal Investigator
    ACRI#037077     (TACKETT, ALAN J)Feb 1, 2017 - Jul 30, 2017
    UAMS ACHRI Flow Through
    N. Avaritt ACHRI Staff – QuickStrike
    Role: Principal Investigator
    R21DA041822     (TACKETT, ALAN)Jul 1, 2016 - Jun 30, 2019
    NIH
    Technology for Identification of Epiproteomes in Tissue Samples
    Role: Principal Investigator
    TBD     (CHEN, JIN-RAN)May 15, 2016 - Apr 30, 2021
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI #035725     (TACKETT, ALAN J)Feb 1, 2016 - Feb 29, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#035725     (TACKETT, ALAN J)Feb 1, 2016 - Feb 29, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACHRI# TBD     (TACKETT, ALAN J)Feb 1, 2016 - Jun 30, 2016
    UAMS ACHRI Flow Through
    N. Avaritt ACHRI Recruitment-Quick Strike
    Role: Principal Investigator
    ACHRI#TBD     (TACKETT, ALAN J)Feb 1, 2016 - Jun 30, 2016
    UAMS ACHRI Flow Through
    N. Avaritt ACHRI Recruitment-Quick Strike
    Role: Principal Investigator
    117     (CHILDS, GWEN V)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    No FP attached
    Role: Principal Investigator
    117-1005573     (TACKETT, ALAN J)Jul 1, 2015 - Jun 30, 2016
    UAMS College of Medicine
    Tackett Start Up Account
    Role: Principal Investigator
    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - May 31, 2025
    NIH
    Center for Studies of Host Response to Cancer Therapy
    Role: Co-Investigator
    R01AI119380     (SMELTZER, MARK S)Jun 15, 2015 - Aug 31, 2026
    NIH
    Defining the role of post-translational regulation by extracellular proteases in the pathogenesis of Staphylococcus aureus osteomyelitis
    Role: Co-Principal Investigator
    R21ES025268     (TACKETT, ALAN)Apr 8, 2015 - Mar 31, 2018
    NIH
    Identifying the Epigenetic Regulation of Arsenic Exposure
    Role: Principal Investigator
    R01DK102206     (BALDINI, GIULIA)Sep 15, 2014 - Aug 31, 2020
    NIH
    Lipid Stress and MC4R
    Role: Co-Investigator
    NCC 9-58 95     (BOERMA, MARJAN)Sep 1, 2014 - May 31, 2017
    National Space Biomedical Research Institute - Pass Through: Baylor College of Medicine
    Team Leader for the Radiation Effects Team
    Role: Co-Investigator
    NCC9-58     (BOERMA, MARJAN)Jun 1, 2014 - May 31, 2017
    National Space Biomedical Research Institute
    Center for Research on Cardiac and Vascular Effects of Space Radiation
    Role: Co-Investigator
    R15ES022781     (AYKIN-BURNS, NUKHET)Sep 13, 2013 - Aug 31, 2017
    NIH
    Sirt3: A Key Player Against PCB-Induced Mitochondrial Injury
    Role: Co-Investigator
    R33CA173264     (TACKETT, ALAN)Sep 1, 2013 - Aug 31, 2017
    NIH
    Development of MassSQUIRM to Quantitatively Measure Lysine Methylation
    Role: Principal Investigator
    R01GM106024     (TAVERNA, SEAN D.)Jul 1, 2013 - Apr 30, 2018
    NIH
    Using ChAP-MS to Study Macromolecular Chromatin Composition during Transcription
    Role: Co-Principal Investigator
    R01AR060823     (MORELLO, ROY)Sep 17, 2012 - Jul 31, 2018
    NIH
    Role of the Leprecan Genes in Skeletal Formation
    Role: Co-Investigator
    HHSO100201100045C     (HAUER-JENSEN, MARTIN)Sep 26, 2011 - Jun 30, 2017
    DHHS - Biomedical Advanced Research and Development Authority
    Advanced Development of SOM230 as a Radiation Mitigator
    Role: Co-Investigator
    P30RR031154     (TACKETT, ALAN)Sep 1, 2010 - May 31, 2015
    NIH/Nat. Center for Research Resources - Pass Through: University of Arkansas at Fayetteville
    NIH COBRE Center for Protein Structure and Function
    Role: Principal Investigator
    R01DK080424     (BALDINI, GIULIA)Jun 1, 2009 - Sep 30, 2014
    NIH
    Melanocortin-4 Receptor Traffic and Signaling
    Role: Co-Investigator
    R01DA025755     (TACKETT, ALAN JACKSON)Sep 20, 2008 - Jul 31, 2013
    NIH
    Development of technology for high resolution epigenetic profiling of chromatin
    Role: Principal Investigator
    R01GM081766     (WAHLS, WAYNE P)Aug 10, 2007 - May 31, 2020
    NIH
    Biochemistry of recombination in meiosis
    Role: Co-Investigator
    R56DK076735     (DRANOFF, JONATHAN A)Dec 1, 2006 - Aug 31, 2016
    NIH
    Regulation of hepatic stellate cells by intracellular calcium
    Role: Co-Investigator
    F32GM066496     (TACKETT, ALAN JACKSON)Sep 1, 2002 - Aug 31, 2005
    NIH
    Analysis of Proteins Involed in Genome Duplication
    Role: Principal Investigator
    P20GM103429     (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2025
    NIH
    Partnerships for Biomedical Research in Arkansas
    Role: Co-Investigator
    P20RR016460     (CORNETT, LAWRENCE E)Sep 30, 2001 - Apr 30, 2015
    NIH
    Partnerships for Biomedical Research in Arkansas
    Role: Co-Investigator
    P01AG012411     (GRIFFIN, SUE TILTON)Jun 1, 1995 - May 31, 2021
    NIH
    Early Events in Alzheimer Pathogenesis
    Role: Co-Investigator
    R01HL050545     (WARE, JERRY)May 1, 1994 - May 31, 2014
    NIH
    Transgenic analysis of platelet receptor expression
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
    List All   |   Timeline
    1. Garg S, Morehead LC, Bird JT, Graw S, Gies A, Storey AJ, Tackett AJ, Edmondson RD, Mackintosh SG, Byrum SD, Miousse IR. Characterization of methionine dependence in melanoma cells. Mol Omics. 2024 Jan 15; 20(1):37-47. PMID: 37782107.
      View in: PubMed
    2. Urbaniak A, Bathula C, Chauhan J, Rai P, Thammathong J, Clark C, Heflin B, De Loose A, Avaritt N, Rodriguez A, Tackett AJ, Sen S, Banerjee S. Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues. Chem Biodivers. 2023 Dec; 20(12):e202301550. PMID: 37994208.
      View in: PubMed
    3. Zhao S, Lu J, Pan B, Fan H, Byrum SD, Xu C, Kim A, Guo Y, Kanchi KL, Gong W, Sun T, Storey AJ, Burkholder NT, Mackintosh SG, Kuhlers PC, Edmondson RD, Strahl BD, Diao Y, Tackett AJ, Raab JR, Cai L, Song J, Wang GG. TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature. 2023 Nov; 623(7987):633-642. PMID: 37938770.
      View in: PubMed
    4. Morehead LC, Koss B, Fil D, Heflin B, Garg S, Wallis KF, Tackett AJ, Miousse IR. Resveratrol induces major histocompatibility complex class I antigen presentation in a STING-dependent and independent manner in melanoma. Mol Immunol. 2023 11; 163:188-195. PMID: 37837954.
      View in: PubMed
    5. Morehead LC, Garg S, Wallis KF, Simoes CC, Siegel ER, Tackett AJ, Miousse IR. Increased Response to Immune Checkpoint Inhibitors with Dietary Methionine Restriction in a Colorectal Cancer Model. Cancers (Basel). 2023 Sep 07; 15(18). PMID: 37760436.
      View in: PubMed
    6. Alam J, Huda MN, Tackett AJ, Miah S. Oncogenic signaling-mediated regulation of chromatin during tumorigenesis. Cancer Metastasis Rev. 2023 06; 42(2):409-425. PMID: 37147457.
      View in: PubMed
    7. Kore RA, Jenkins SV, Jamshidi-Parsian A, Tackett AJ, Griffin RJ, Ayyadevara S, Mehta JL. Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes. Biochem Biophys Rep. 2023 Jul; 34:101463. PMID: 37125076.
      View in: PubMed
    8. Morehead LC, Garg S, Wallis KF, Siegel ER, Tackett AJ, Miousse IR. Increased response to immune checkpoint inhibitors with dietary methionine restriction. bioRxiv. 2023 Apr 06. PMID: 37066240.
      View in: PubMed
    9. Garg S, Morehead LC, Bird JT, Graw S, Gies A, Storey AJ, Tackett AJ, Edmondson RD, Mackintosh SG, Byrum SD, Miousse IR. Characterization of methionine dependence in melanoma cells. bioRxiv. 2023 Apr 05. PMID: 37066392.
      View in: PubMed
    10. Roy Choudhury S, Heflin B, Taylor E, Koss B, Avaritt NL, Tackett AJ. CRISPR/dCas9-KRAB-Mediated Suppression of S100b Restores p53-Mediated Apoptosis in Melanoma Cells. Cells. 2023 02 24; 12(5). PMID: 36899866.
      View in: PubMed
    11. Lowenthal R, Taylor M, Gidden JA, Heflin B, Lay JO, Avaritt N, Tackett AJ, Urbaniak A. The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro. Biomed Pharmacother. 2023 May; 161:114424. PMID: 36827712.
      View in: PubMed
    12. Roy Choudhury S, Byrum SD, Alkam D, Ashby C, Zhan F, Tackett AJ, Van Rhee F. Expression of integrin ?-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics. Clin Epigenetics. 2023 02 04; 15(1):18. PMID: 36737807.
      View in: PubMed
    13. Urbaniak A, Reed MR, Heflin B, Gaydos J, Pi?a-Oviedo S, Jedrzejczyk M, Klejborowska G, Stepczynska N, Chambers TC, Tackett AJ, Rodriguez A, Huczynski A, Eoff RL, MacNicol AM. Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer. Biomed Pharmacother. 2022 Sep; 153:113440. PMID: 36076555.
      View in: PubMed
    14. Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2022 May 12; 12(1):7874. PMID: 35551219.
      View in: PubMed
    15. Li D, Yu X, Kottur J, Gong W, Zhang Z, Storey AJ, Tsai YH, Uryu H, Shen Y, Byrum SD, Edmondson RD, Mackintosh SG, Cai L, Liu Z, Aggarwal AK, Tackett AJ, Liu J, Jin J, Wang GG. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022 06; 41(24):3328-3340. PMID: 35525905.
      View in: PubMed
    16. Wardell CP, Darrigues E, De Loose A, Lee MP, Gokden M, Makhoul I, Tackett AJ, Rodriguez A. Genomic and Transcriptomic Profiling of Brain Metastases. Cancers (Basel). 2021 Nov 09; 13(22). PMID: 34830758.
      View in: PubMed
    17. Paidi SK, Rodriguez Troncoso J, Raj P, Monterroso Diaz P, Ivers JD, Lee DE, Avaritt NL, Gies AJ, Quick CM, Byrum SD, Tackett AJ, Rajaram N, Barman I. Raman Spectroscopy and Machine Learning Reveals Early Tumor Microenvironmental Changes Induced by Immunotherapy. Cancer Res. 2021 11 15; 81(22):5745-5755. PMID: 34645610.
      View in: PubMed
    18. Delgado M, Washam CL, Urbaniak A, Heflin B, Storey AJ, Lan RS, Mackintosh SG, Tackett AJ, Byrum SD, Chambers TC. Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle. ACS Omega. 2021 Sep 28; 6(38):24949-24959. PMID: 34604676.
      View in: PubMed
    19. Xu C, Meng F, Park KS, Storey AJ, Gong W, Tsai YH, Gibson E, Byrum SD, Li D, Edmondson RD, Mackintosh SG, Vedadi M, Cai L, Tackett AJ, Kaniskan H?, Jin J, Wang GG. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell Chem Biol. 2022 03 17; 29(3):386-397.e9. PMID: 34469831.
      View in: PubMed
    20. Wang Y, Liu S, Yang Z, Algazi AP, Lomeli SH, Wang Y, Othus M, Hong A, Wang X, Randolph CE, Jones AM, Bosenberg MW, Byrum SD, Tackett AJ, Lopez H, Yates C, Solit DB, Ribas A, Piva M, Moriceau G, Lo RS. Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy. Cancer Cell. 2021 10 11; 39(10):1375-1387.e6. PMID: 34416167.
      View in: PubMed
    21. Ahn JH, Davis ES, Daugird TA, Zhao S, Quiroga IY, Uryu H, Li J, Storey AJ, Tsai YH, Keeley DP, Mackintosh SG, Edmondson RD, Byrum SD, Cai L, Tackett AJ, Zheng D, Legant WR, Phanstiel DH, Wang GG. Phase separation drives aberrant chromatin looping and cancer development. Nature. 2021 07; 595(7868):591-595. PMID: 34163069.
      View in: PubMed
    22. Xu C, Tsai YH, Galbo PM, Gong W, Storey AJ, Xu Y, Byrum SD, Xu L, Whang YE, Parker JS, Mackintosh SG, Edmondson RD, Tackett AJ, Huang J, Zheng D, Earp HS, Wang GG, Cai L. Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer. Nucleic Acids Res. 2021 05 21; 49(9):4971-4988. PMID: 33849067.
      View in: PubMed
    23. Fan H, Guo Y, Tsai YH, Storey AJ, Kim A, Gong W, Edmondson RD, Mackintosh SG, Li H, Byrum SD, Tackett AJ, Cai L, Wang GG. A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing. Nucleic Acids Res. 2021 05 07; 49(8):4441-4455. PMID: 33823544.
      View in: PubMed
    24. Reed MR, Maddukuri L, Ketkar A, Byrum SD, Zafar MK, Bostian ACL, Tackett AJ, Eoff RL. Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells. NAR Cancer. 2021 Jun; 3(2):zcab014. PMID: 33870196.
      View in: PubMed
    25. Jenkins SV, Alimohammadi M, Terry AS, Griffin RJ, Tackett AJ, Leung JW, Vang KB, Byrum SD, Dings RPM. Dysbiotic stress increases the sensitivity of the tumor vasculature to radiotherapy and c-Met inhibitors. Angiogenesis. 2021 08; 24(3):597-611. PMID: 33629198.
      View in: PubMed
    26. Li J, Galbo PM, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nat Commun. 2021 02 16; 12(1):1045. PMID: 33594072.
      View in: PubMed
    27. Kore RA, Wang X, Ding Z, Griffin RJ, Tackett AJ, Mehta JL. MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas. Mol Cell Biochem. 2021 Apr; 476(4):1691-1704. PMID: 33423165.
      View in: PubMed
    28. Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2021 03; 11(3):714-735. PMID: 33318037.
      View in: PubMed
    29. Ramirez AM, Beenken KE, Byrum SD, Tackett AJ, Shaw LN, Gimza BD, Smeltzer MS. SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1. Virulence. 2020 12; 11(1):1738-1762. PMID: 33258416.
      View in: PubMed
    30. Koss B, Shields BD, Taylor EM, Storey AJ, Byrum SD, Gies AJ, Washam CL, Choudhury SR, Hyun Ahn J, Uryu H, Williams JB, Krager KJ, Chiang TC, Mackintosh SG, Edmondson RD, Aykin-Burns N, Gajewski TF, Wang GG, Tackett AJ. Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer Res. 2020 11 01; 80(21):4707-4719. PMID: 33004350.
      View in: PubMed
    31. Karaduta O, Glazko G, Dvanajscak Z, Arthur J, Mackintosh S, Orr L, Rahmatallah Y, Yeruva L, Tackett A, Zybailov B. Resistant starch slows the progression of CKD in the 5/6 nephrectomy mouse model. Physiol Rep. 2020 10; 8(19):e14610. PMID: 33038060.
      View in: PubMed
    32. Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Holley J, Sridharan V, Boerma M, Tackett AJ, Willey JS, Pecaut MJ, Delp MD. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. FASEB J. 2020 11; 34(11):15516-15530. PMID: 32981077.
      View in: PubMed
    33. Taylor EM, Byrum SD, Edmondson JL, Wardell CP, Griffin BG, Shalin SC, Gokden M, Makhoul I, Tackett AJ, Rodriguez A. Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta Neuropathol Commun. 2020 09 05; 8(1):157. PMID: 32891176.
      View in: PubMed
    34. Waldrip ZJ, Jenjaroenpun P, DeYoung O, Nookaew I, Taverna SD, Raney KD, Tackett AJ. Genome-wide Cas9 binding specificity in Saccharomyces cerevisiae. PeerJ. 2020; 8:e9442. PMID: 32821531.
      View in: PubMed
    35. Storey AJ, Naceanceno KS, Lan RS, Washam CL, Orr LM, Mackintosh SG, Tackett AJ, Edmondson RD, Wang Z, Li HY, Frett B, Kendrick S, Byrum SD. ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Mol Omics. 2020 08 01; 16(4):316-326. PMID: 32347222.
      View in: PubMed
    36. Davis LE, Shalin SC, Tackett AJ. Utility of histone H3K27me3 and H4K20me as diagnostic indicators of melanoma. Melanoma Res. 2020 04; 30(2):159-165. PMID: 32142497.
      View in: PubMed
    37. Storey AJ, Hardman RE, Byrum SD, Mackintosh SG, Edmondson RD, Wahls WP, Tackett AJ, Lewis JA. Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags. J Proteome Res. 2020 03 06; 19(3):1183-1195. PMID: 32027144.
      View in: PubMed
    38. Trentzsch M, Nyamugenda E, Miles TK, Griffin H, Russell S, Koss B, Cooney KA, Phelan KD, Tackett AJ, Iyer S, Boysen G, Baldini G. Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum. Cell Death Discov. 2020; 6:8. PMID: 32123584.
      View in: PubMed
    39. Taylor EM, Koss B, Davis LE, Tackett AJ. Histone Modifications as Biomarkers for Immunotherapy. Methods Mol Biol. 2020; 2055:213-228. PMID: 31502154.
      View in: PubMed
    40. Kore RA, Henson JC, Hamzah RN, Griffin RJ, Tackett AJ, Ding Z, Mehta JL. Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes. Sci Rep. 2019 12 17; 9(1):19276. PMID: 31848380.
      View in: PubMed
    41. Ramirez AM, Byrum SD, Beenken KE, Washam C, Edmondson RD, Mackintosh SG, Spencer HJ, Tackett AJ, Smeltzer MS. Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS Infect Dis. 2020 02 14; 6(2):237-249. PMID: 31722523.
      View in: PubMed
    42. Byrum SD, Washam CL, Tackett AJ, Garcia-Rill E, Bisagno V, Urbano FJ. Proteomic measures of gamma oscillations. Heliyon. 2019 Aug; 5(8):e02265. PMID: 31497668.
      View in: PubMed
    43. Ren Z, Ahn JH, Liu H, Tsai YH, Bhanu NV, Koss B, Allison DF, Ma A, Storey AJ, Wang P, Mackintosh SG, Edmondson RD, Groen RWJ, Martens AC, Garcia BA, Tackett AJ, Jin J, Cai L, Zheng D, Wang GG. PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. Blood. 2019 10 03; 134(14):1176-1189. PMID: 31383640.
      View in: PubMed
    44. Davis LE, Shalin SC, Tackett AJ. Current state of melanoma diagnosis and treatment. Cancer Biol Ther. 2019; 20(11):1366-1379. PMID: 31366280.
      View in: PubMed
    45. Chiang TC, Koss B, Su LJ, Washam CL, Byrum SD, Storey A, Tackett AJ. Effect of Sulforaphane and 5-Aza-2'-Deoxycytidine on Melanoma Cell Growth. Medicines (Basel). 2019 Jun 27; 6(3). PMID: 31252639.
      View in: PubMed
    46. Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Drew A, Sridharan V, Boerma M, Tackett AJ, Zawieja D, Willey JS, Delp M, Pecaut MJ. Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations. Sci Rep. 2019 06 03; 9(1):8215. PMID: 31160660.
      View in: PubMed
    47. Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem. 2019 07 12; 294(28):10969-10986. PMID: 31152063.
      View in: PubMed
    48. Lo S, Byrum SD, Tackett AJ, Parajuli N. Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage. Transplant Direct. 2019 Jun; 5(6):e454. PMID: 31723591.
      View in: PubMed
    49. Garcia-Rill E, Tackett AJ, Byrum SD, Lan RS, Mackintosh SG, Hyde JR, Bisagno V, Urbano FJ. Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus. Brain Sci. 2019 Mar 18; 9(3). PMID: 30889866.
      View in: PubMed
    50. West KL, Byrum SD, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ. Proteomic characterization of the arsenic response locus in S. cerevisiae. Epigenetics. 2019 02; 14(2):130-145. PMID: 30739529.
      View in: PubMed
    51. Zybailov BL, Glazko GV, Rahmatallah Y, Andreyev DS, McElroy T, Karaduta O, Byrum SD, Orr L, Tackett AJ, Mackintosh SG, Edmondson RD, Kieffer DA, Martin RJ, Adams SH, Vaziri ND, Arthur JM. Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats. PLoS One. 2019; 14(1):e0199274. PMID: 30699108.
      View in: PubMed
    52. Shields BD, Koss B, Taylor EM, Storey AJ, West KL, Byrum SD, Mackintosh SG, Edmondson R, Mahmoud F, Shalin SC, Tackett AJ. Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma. Cancer Res. 2019 03 15; 79(6):1113-1123. PMID: 30674537.
      View in: PubMed
    53. Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY. An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells. Biochem Pharmacol. 2019 02; 160:134-145. PMID: 30578766.
      View in: PubMed
    54. Storey AJ, Wang HP, Protacio RU, Davidson MK, Tackett AJ, Wahls WP. Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot. Epigenetics Chromatin. 2018 10 29; 11(1):64. PMID: 30373637.
      View in: PubMed
    55. Byrum SD, Loughran AJ, Beenken KE, Orr LM, Storey AJ, Mackintosh SG, Edmondson RD, Tackett AJ, Smeltzer MS. Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome. J Proteome Res. 2018 10 05; 17(10):3384-3395. PMID: 30209945.
      View in: PubMed
    56. Mao XW, Byrum S, Nishiyama NC, Pecaut MJ, Sridharan V, Boerma M, Tackett AJ, Shiba D, Shirakawa M, Takahashi S, Delp MD. Impact of Spaceflight and Artificial Gravity on the Mouse Retina: Biochemical and Proteomic Analysis. Int J Mol Sci. 2018 Aug 28; 19(9). PMID: 30154332.
      View in: PubMed
    57. Kriss CL, Gregory-Lott E, Storey AJ, Tackett AJ, Wahls WP, Stevens SM. In Vivo Metabolic Tracing Demonstrates the Site-Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation. Alcohol Clin Exp Res. 2018 10; 42(10):1909-1923. PMID: 30030934.
      View in: PubMed
    58. Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463. PMID: 30070965.
      View in: PubMed
    59. Zhang X, Zhang S, Liu X, Wang Y, Chang J, Zhang X, Mackintosh SG, Tackett AJ, He Y, Lv D, Laberge RM, Campisi J, Wang J, Zheng G, Zhou D. Oxidation resistance 1 is a novel senolytic target. Aging Cell. 2018 08; 17(4):e12780. PMID: 29766639.
      View in: PubMed
    60. McSweeney JC, Hudson TJ, Prince L, Bene? H, Tackett AJ, Miller Robinson C, Koeppe R, Cornett LE. Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas. Adv Physiol Educ. 2018 Mar 01; 42(1):123-129. PMID: 29446316.
      View in: PubMed
    61. Holthoff ER, Byrum SD, Mackintosh SG, Kelly T, Tackett AJ, Quick CM, Post SR. Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1. Clin Proteomics. 2017; 14:40. PMID: 29225558.
      View in: PubMed
    62. Wang P, Byrum S, Fowler FC, Pal S, Tackett AJ, Tyler JK. Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break. Nucleic Acids Res. 2017 Nov 02; 45(19):10923-10940. PMID: 29036368.
      View in: PubMed
    63. Miousse IR, Pathak R, Garg S, Skinner CM, Melnyk S, Pavliv O, Hendrickson H, Landes RD, Lumen A, Tackett AJ, Deutz NEP, Hauer-Jensen M, Koturbash I. Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology. Genes Nutr. 2017; 12:22. PMID: 28904640.
      View in: PubMed
    64. Oliveira C, Gunderman L, Coles CA, Lochmann J, Parks M, Ballard E, Glazko G, Rahmatallah Y, Tackett AJ, Thomas DJ. 16S rRNA Gene-Based Metagenomic Analysis of Ozark Cave Bacteria. Diversity (Basel). 2017 Sep; 9(3). PMID: 29551950.
      View in: PubMed
    65. Kim Wiese A, Schluterman Burdine M, Turnage RH, Tackett AJ, Burdine LJ. DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes. PLoS One. 2017; 12(7):e0181608. PMID: 28750002.
      View in: PubMed
    66. Miousse IR, Chang J, Shao L, Pathak R, Nzabarushimana ?, Kutanzi KR, Landes RD, Tackett AJ, Hauer-Jensen M, Zhou D, Koturbash I. Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation. Int J Mol Sci. 2017 Jul 04; 18(7). PMID: 28677663.
      View in: PubMed
    67. Firwana B, Avaritt N, Shields B, Ravilla R, Makhoul I, Hutchins L, Tackett AJ, Mahmoud F. Do checkpoint inhibitors rely on gut microbiota to fight cancer? J Oncol Pharm Pract. 2018 Sep; 24(6):468-472. PMID: 28625074.
      View in: PubMed
    68. Mahmoud F, Shields B, Makhoul I, Avaritt N, Wong HK, Hutchins LF, Shalin S, Tackett AJ. Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack. Cancer Biol Ther. 2017 Jul 03; 18(7):451-469. PMID: 28513269.
      View in: PubMed
    69. Shields BD, Mahmoud F, Taylor EM, Byrum SD, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh SG, Edmondson RD, Shalin S, Tackett AJ. Indicators of responsiveness to immune checkpoint inhibitors. Sci Rep. 2017 04 11; 7(1):807. PMID: 28400597.
      View in: PubMed
    70. Byrum SD, Burdine MS, Orr L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection. PLoS One. 2017; 12(3):e0174771. PMID: 28350824.
      View in: PubMed
    71. Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, MacMillan-Crow LA, Hallberg LM, Ameredes BT, Boysen G. 1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice. Toxicology. 2017 03 01; 378:114-124. PMID: 28082109.
      View in: PubMed
    72. Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY). 2016 12 15; 8(12):3486-3497. PMID: 27992858.
      View in: PubMed
    73. Blair LP, Liu Z, Labitigan RL, Wu L, Zheng D, Xia Z, Pearson EL, Nazeer FI, Cao J, Lang SM, Rines RJ, Mackintosh SG, Moore CL, Li W, Tian B, Tackett AJ, Yan Q. KDM5 lysine demethylases are involved in maintenance of 3'UTR length. Sci Adv. 2016 Nov; 2(11):e1501662. PMID: 28138513.
      View in: PubMed
    74. Yale K, Tackett AJ, Neuman M, Bulley E, Chait BT, Wiley E. Phosphorylation-Dependent Targeting of Tetrahymena HP1 to Condensed Chromatin. mSphere. 2016 Jul-Aug; 1(4). PMID: 27579368.
      View in: PubMed
    75. Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS. Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus. Infect Immun. 2016 09; 84(9):2586-94. PMID: 27354444.
      View in: PubMed
    76. Ayyadevara S, Balasubramaniam M, Parcon PA, Barger SW, Griffin WS, Alla R, Tackett AJ, Mackintosh SG, Petricoin E, Zhou W, Shmookler Reis RJ. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls. Aging Cell. 2016 10; 15(5):924-39. PMID: 27448508.
      View in: PubMed
    77. Prior S, Miousse IR, Nzabarushimana E, Pathak R, Skinner C, Kutanzi KR, Allen AR, Raber J, Tackett AJ, Hauer-Jensen M, Nelson GA, Koturbash I. Densely ionizing radiation affects DNA methylation of selective LINE-1 elements. Environ Res. 2016 10; 150:470-481. PMID: 27419368.
      View in: PubMed
    78. Boerma M, Sridharan V, Mao XW, Nelson GA, Cheema AK, Koturbash I, Singh SP, Tackett AJ, Hauer-Jensen M. Effects of ionizing radiation on the heart. Mutat Res Rev Mutat Res. 2016 Oct - Dec; 770(Pt B):319-327. PMID: 27919338.
      View in: PubMed
    79. Shields BD, Tackett AJ, Shalin SC. Proteomics and melanoma: a current perspective. Glob Dermatol. 2016 Aug; 3(4):366-370. PMID: 30214824.
      View in: PubMed
    80. Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Mol Cell. 2016 05 19; 62(4):558-71. PMID: 27132940.
      View in: PubMed
    81. Heard ME, Besio R, Weis M, Rai J, Hudson DM, Dimori M, Zimmerman SM, Kamykowski JA, Hogue WR, Swain FL, Burdine MS, Mackintosh SG, Tackett AJ, Suva LJ, Eyre DR, Morello R. Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. PLoS Genet. 2016 Apr; 12(4):e1006002. PMID: 27119146.
      View in: PubMed
    82. Sengupta D, Tackett AJ. Proteomic Findings in Melanoma. J Proteomics Bioinform. 2016 Apr; 9(4). PMID: 27274624.
      View in: PubMed
    83. Mahmoud F, Shields B, Makhoul I, Hutchins LF, Shalin SC, Tackett AJ. Role of EZH2 histone methyltrasferase in melanoma progression and metastasis. Cancer Biol Ther. 2016 06 02; 17(6):579-91. PMID: 27105109.
      View in: PubMed
    84. Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature. 2016 Apr 21; 532(7599):329-33. PMID: 27027282.
      View in: PubMed
    85. Ayyadevara S, Mercanti F, Wang X, Mackintosh SG, Tackett AJ, Prayaga SV, Romeo F, Shmookler Reis RJ, Mehta JL. Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles. Hypertension. 2016 May; 67(5):1006-13. PMID: 26975704.
      View in: PubMed
    86. Shields B, Shalin SC, Tackett AJ. Microscopes and Mass Spectrometers. J Proteomics Bioinform. 2016; 9(Suppl 10). PMID: 29910559.
      View in: PubMed
    87. Byrum SD, Burdine MS, Orr L, Moreland L, Mackintosh SG, Authier S, Pouliot M, Hauer-Jensen M, Tackett AJ. A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates. J Proteomics Bioinform. 2016; 9(Suppl 10). PMID: 26962295.
      View in: PubMed
    88. Sengupta D, Byrum SD, Avaritt NL, Davis L, Shields B, Mahmoud F, Reynolds M, Orr LM, Mackintosh SG, Shalin SC, Tackett AJ. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016 Mar; 15(3):765-75. PMID: 26621846.
      View in: PubMed
    89. Salinas E, Byrum SD, Moreland LE, Mackintosh SG, Tackett AJ, Forrest JC. Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. J Virol. 2016 02 01; 90(3):1397-413. PMID: 26581985.
      View in: PubMed
    90. Haun RS, Quick CM, Siegel ER, Raju I, Mackintosh SG, Tackett AJ. Bioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkers. Cancer Biol Ther. 2015; 16(10):1557-65. PMID: 26176765.
      View in: PubMed
    91. Burdine LJ, Burdine MS, Moreland L, Fogel B, Orr LM, James J, Turnage RH, Tackett AJ. Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway. PLoS One. 2015; 10(6):e0127943. PMID: 26065416.
      View in: PubMed
    92. Sengupta D, Kannan A, Kern M, Moreno MA, Vural E, Stack B, Suen JY, Tackett AJ, Gao L. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma. Epigenetics. 2015; 10(6):460-6. PMID: 25941994.
      View in: PubMed
    93. Gao J, Zybailov BL, Byrd AK, Griffin WC, Chib S, Mackintosh SG, Tackett AJ, Raney KD. Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA. Chem Commun (Camb). 2015 Apr 28; 51(33):7242-4. PMID: 25813861.
      View in: PubMed
    94. Byrum SD, Taverna SD, Tackett AJ. Purification of specific chromatin loci for proteomic analysis. Methods Mol Biol. 2015; 1228:83-92. PMID: 25311124.
      View in: PubMed
    95. Papazyan R, Voronina E, Chapman JR, Luperchio TR, Gilbert TM, Meier E, Mackintosh SG, Shabanowitz J, Tackett AJ, Reddy KL, Coyne RS, Hunt DF, Liu Y, Taverna SD. Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. Elife. 2014 Aug 26; 3:e02996. PMID: 25161194.
      View in: PubMed
    96. Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD. The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3. Mol Cell Proteomics. 2014 Nov; 13(11):2896-910. PMID: 25106422.
      View in: PubMed
    97. Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol Cell Proteomics. 2014 Nov; 13(11):2883-95. PMID: 25104842.
      View in: PubMed
    98. Waldrip ZJ, Byrum SD, Storey AJ, Gao J, Byrd AK, Mackintosh SG, Wahls WP, Taverna SD, Raney KD, Tackett AJ. A CRISPR-based approach for proteomic analysis of a single genomic locus. Epigenetics. 2014 Sep; 9(9):1207-11. PMID: 25147920.
      View in: PubMed
    99. Udensi UK, Tackett AJ, Byrum S, Avaritt NL, Sengupta D, Moreland LW, Tchounwou PB, Isokpehi RD. Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide. J Proteomics Bioinform. 2014 Jul; 7(7):166-178. PMID: 25419056.
      View in: PubMed
    100. Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20; 9(6):1284-93. PMID: 24707965.
      View in: PubMed
    101. Zhu B, Zhang M, Byrum SD, Tackett AJ, Davie JK. TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells. Int J Cancer. 2014 Aug 15; 135(4):785-97. PMID: 24470334.
      View in: PubMed
    102. Haun RS, Fan CY, Mackintosh SG, Zhao H, Tackett AJ. CD109 Overexpression in Pancreatic Cancer Identified by Cell-Surface Glycoprotein Capture. J Proteomics Bioinform. 2014; Suppl 10:S10003. PMID: 25635161.
      View in: PubMed
    103. Shao Q, Byrum SD, Moreland LE, Mackintosh SG, Kannan A, Lin Z, Morgan M, Stack BC, Cornelius LA, Tackett AJ, Gao L. A Proteomic Study of Human Merkel Cell Carcinoma. J Proteomics Bioinform. 2013 Nov 25; 6:275-282. PMID: 25284964.
      View in: PubMed
    104. Hammond SL, Byrum SD, Namjoshi S, Graves HK, Dennehey BK, Tackett AJ, Tyler JK. Mitotic phosphorylation of histone H3 threonine 80. Cell Cycle. 2014; 13(3):440-52. PMID: 24275038.
      View in: PubMed
    105. Byrum SD, Taverna SD, Tackett AJ. Purification of a specific native genomic locus for proteomic analysis. Nucleic Acids Res. 2013 Nov; 41(20):e195. PMID: 24030711.
      View in: PubMed
    106. Washam CL, Byrum SD, Leitzel K, Ali SM, Tackett AJ, Gaddy D, Sundermann SE, Lipton A, Suva LJ. Identification of PTHrP(12-48) as a plasma biomarker associated with breast cancer bone metastasis. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):972-83. PMID: 23462923.
      View in: PubMed
    107. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013; 6(3):43-50.
    108. Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ. Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma. J Proteomics Bioinform. 2013 Mar 01; 6(3):43-50. PMID: 23976835.
      View in: PubMed
    109. Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem. 2013 Mar 29; 288(13):9408-17. PMID: 23408432.
      View in: PubMed
    110. Lolis AA, Londhe P, Beggs BC, Byrum SD, Tackett AJ, Davie JK. Myogenin recruits the histone chaperone facilitates chromatin transcription (FACT) to promote nucleosome disassembly at muscle-specific genes. J Biol Chem. 2013 Mar 15; 288(11):7676-7687. PMID: 23364797.
      View in: PubMed
    111. Ramanagoudr-Bhojappa R, Blair LP, Tackett AJ, Raney KD. Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein. Nucleic Acids Res. 2013 Jan; 41(2):1029-46. PMID: 23175612.
      View in: PubMed
    112. Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96. PMID: 23075270.
      View in: PubMed
    113. Suter MA, Chen A, Burdine MS, Choudhury M, Harris RA, Lane RH, Friedman JE, Grove KL, Tackett AJ, Aagaard KM. A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J. 2012 Dec; 26(12):5106-14. PMID: 22982377.
      View in: PubMed
    114. Byrum SD, Raman A, Taverna SD, Tackett AJ. ChAP-MS: a method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Rep. 2012 Jul 26; 2(1):198-205. PMID: 22840409.
      View in: PubMed
    115. Avaritt NL, Owens R, Larson SK, Reynolds M, Byrum S, Hiatt KM, Smoller BR, Tackett AJ, Cheung WL. Misregulation of Rad50 expression in melanoma cells. J Cutan Pathol. 2012 Jul; 39(7):680-684. PMID: 22725639.
      View in: PubMed
    116. Blair LP, Avaritt NL, Tackett AJ. Application of MassSQUIRM for quantitative measurements of lysine demethylase activity. J Vis Exp. 2012 Mar 11; (61). PMID: 22433969.
      View in: PubMed
    117. Byrum SD, Washam CL, Montgomery CO, Tackett AJ, Suva LJ. Proteomic technologies for the study of osteosarcoma. Sarcoma. 2012; 2012:169416. PMID: 22550414.
      View in: PubMed
    118. Arumugam K, MacNicol MC, Wang Y, Cragle CE, Tackett AJ, Hardy LL, MacNicol AM. Ringo/cyclin-dependent kinase and mitogen-activated protein kinase signaling pathways regulate the activity of the cell fate determinant Musashi to promote cell cycle re-entry in Xenopus oocytes. J Biol Chem. 2012 Mar 23; 287(13):10639-10649. PMID: 22215682.
      View in: PubMed
    119. Byrum S, Smart SK, Larson S, Tackett AJ. Analysis of stable and transient protein-protein interactions. Methods Mol Biol. 2012; 833:143-52. PMID: 22183593.
      View in: PubMed
    120. Byrum S, Avaritt NL, Mackintosh SG, Munkberg JM, Badgwell BD, Cheung WL, Tackett AJ. A quantitative proteomic analysis of FFPE melanoma. J Cutan Pathol. 2011 Nov; 38(11):933-6. PMID: 21883366.
      View in: PubMed
    121. Byrum SD, Taverna SD, Tackett AJ. Quantitative analysis of histone exchange for transcriptionally active chromatin. J Clin Bioinforma. 2011 Jul 07; 1(1):17. PMID: 21884633.
      View in: PubMed
    122. Blair LP, Avaritt NL, Huang R, Cole PA, Taverna SD, Tackett AJ. MassSQUIRM: An assay for quantitative measurement of lysine demethylase activity. Epigenetics. 2011 Apr; 6(4):490-9. PMID: 21273814.
      View in: PubMed
    123. Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ. Analysis of Histone Exchange during Chromatin Purification. J Integr OMICS. 2011; 1(1):61-5.
    124. Byrum S, Mackintosh SG, Edmondson RD, Cheung WL, Taverna SD, Tackett AJ. Analysis of Histone Exchange during Chromatin Purification. J Integr OMICS. 2011 Feb 01; 1(1):61-65. PMID: 21709819.
      View in: PubMed
    125. Sekedat MD, Feny? D, Rogers RS, Tackett AJ, Aitchison JD, Chait BT. GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol. 2010; 6:353. PMID: 20212525.
      View in: PubMed
    126. Elbein AD, Pastuszak I, Tackett AJ, Wilson T, Pan YT. Last step in the conversion of trehalose to glycogen: a mycobacterial enzyme that transfers maltose from maltose 1-phosphate to glycogen. J Biol Chem. 2010 Mar 26; 285(13):9803-9812. PMID: 20118231.
      View in: PubMed
    127. Smart SK, Mackintosh SG, Edmondson RD, Taverna SD, Tackett AJ. Mapping the local protein interactome of the NuA3 histone acetyltransferase. Protein Sci. 2009 Sep; 18(9):1987-97. PMID: 19621382.
      View in: PubMed
    128. Gradolatto A, Smart SK, Byrum S, Blair LP, Rogers RS, Kolar EA, Lavender H, Larson SK, Aitchison JD, Taverna SD, Tackett AJ. A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. Mol Cell Biol. 2009 Sep; 29(17):4604-11. PMID: 19581291.
      View in: PubMed
    129. Blair LP, Tackett AJ, Raney KD. Development and evaluation of a structural model for SF1B helicase Dda. Biochemistry. 2009 Mar 24; 48(11):2321-9. PMID: 19256528.
      View in: PubMed
    130. Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD. NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations*S?. J Biol Chem. 2009; 284(8):4806-14.
    131. Jennings TA, Mackintosh SG, Harrison MK, Sikora D, Sikora B, Dave B, Tackett AJ, Cameron CE, Raney KD. NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. J Biol Chem. 2009 Feb 20; 284(8):4806-14. PMID: 19088075.
      View in: PubMed
    132. Upreti M, Galitovskaya EN, Chu R, Tackett AJ, Terrano DT, Granell S, Chambers TC. Identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. J Biol Chem. 2008 Dec 19; 283(51):35517-25. PMID: 18974096.
      View in: PubMed
    133. Gradolatto A, Rogers RS, Lavender H, Taverna SD, Allis CD, Aitchison JD, Tackett AJ. Saccharomyces cerevisiae Yta7 regulates histone gene expression. Genetics. 2008 May; 179(1):291-304. PMID: 18493054.
      View in: PubMed
    134. Sikora B, Chen Y, Lichti CF, Harrison MK, Jennings TA, Tang Y, Tackett AJ, Jordan JB, Sakon J, Cameron CE, Raney KD. Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activity in Vitro*S?. J Biol Chem. 2008; 283(17):11516-25.
    135. Hatcher R, Beck M, Tackett A, Pantelides ST. Dynamical effects in the interaction of ion beams with solids. Phys Rev Lett. 2008 Mar 14; 100(10):103201. PMID: 18352184.
      View in: PubMed
    136. Sikora B, Chen Y, Lichti CF, Harrison MK, Jennings TA, Tang Y, Tackett AJ, Jordan JB, Sakon J, Cameron CE, Raney KD. Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem. 2008 Apr 25; 283(17):11516-25. PMID: 18283103.
      View in: PubMed
    137. Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Feny? D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. J Proteome Res. 2008 Mar; 7(3):1244-50. PMID: 18271525.
      View in: PubMed
    138. Upreti, M, Galitovskaya, EN, Chu, R, Tackett AJ, Granell, S, Chambers, TC. Direct biochemical identification of the major phosphorylation site in Bcl-xL induced by microtubule inhibitors and analysis of its functional significance. 2008.
    139. Taverna SD, Ueberheide BM, Liu Y, Tackett AJ, Diaz RL, Shabanowitz J, Chait BT, Hunt DF, Allis CD. Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2086-91. PMID: 17284592.
      View in: PubMed
    140. Taverna SD, Ilin S, Rogers RS, Tanny JC, Lavender H, Li H, Baker L, Boyle J, Blair LP, Chait BT, Patel DJ, Aitchison JD, Tackett AJ, Allis CD. Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell. 2006 Dec 08; 24(5):785-796. PMID: 17157260.
      View in: PubMed
    141. Collom SL, Jamakhandi AP, Tackett AJ, Radominska-Pandya A, Miller GP. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling. Arch Biochem Biophys. 2007 Mar 01; 459(1):59-69. PMID: 17222385.
      View in: PubMed
    142. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature. 2006 Jul 06; 442(7098):86-90. PMID: 16728976.
      View in: PubMed
    143. Guermah M, Palhan VB, Tackett AJ, Chait BT, Roeder RG. Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell. 2006 Apr 21; 125(2):275-86. PMID: 16630816.
      View in: PubMed
    144. Taverna SD, Ilin S, Rogers RS, Tanny JC, Lavender H, Li H, Baker L, Boyle J, Blair LP, Chait BT, Patel DJ, Aitchison JD, Tackett A J (corresponding), Allis C D. Yng 1 PHD finger binding to histone H3 trimethylated at lysine 4 promotes NuA3 HAT activity at lysine 14 of H3 and transcriptional at a subset of targeted ORFs. Mol. Cell. 2006; 24:785-796.
    145. Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodeling. Nature. 2006; 442:86-90.
    146. Dilworth DJ, Tackett AJ, Rogers RS, Yi EC, Christmas RH, Smith JJ, Siegel AF, Chait BT, Wozniak RW, Aitchison JD. The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol. 2005 Dec 19; 171(6):955-65. PMID: 16365162.
      View in: PubMed
    147. Tackett AJ, DeGrasse JA, Sekedat MD, Oeffinger M, Rout MP, Chait BT. I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions. J Proteome Res. 2005 Sep-Oct; 4(5):1752-6. PMID: 16212429.
      View in: PubMed
    148. Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 2005 Jun 17; 121(6):873-85. PMID: 15960975.
      View in: PubMed
    149. Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell M, Aitchison JD, Rout MP, Chait BT. Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol. 2005 Apr 11; 169(1):35-47. PMID: 15824130.
      View in: PubMed
    150. Tackett AJ, Chen Y, Cameron CE, Raney KD. Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro. J Biol Chem. 2005 Mar 18; 280(11):10797-806. PMID: 15634684.
      View in: PubMed
    151. Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell MD, Aitchison JD, Rout MP, Chait BT. Proteomic and genomic characterization of chromatin complexes at boundary. J. Cell. Biol. 2005; 169:35-47.
    152. Tackett AJ, DeGrasse JA, Oeffinger M, Rout MP. IDIRT, A General Method for Distinguished Between Specific and Non Specific Protein Interactions. J.Proteome. Res. 2005; 4:1752-6.
    153. Archambault V, Li CX, Tackett AJ, Wasch R, Chait BT, Rout MP, Cross FR. Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic ExitD?. Mol Biol Cell. 2003; 14(11):4592-604.
    154. Archambault V, Li CX, Tackett AJ, Wasch R, Chait BT, Rout MP, Cross FR. Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exit. Mol Biol Cell. 2003 Nov; 14(11):4592-604. PMID: 12960422.
      View in: PubMed
    155. Tackett AJ, Corey DR, Raney KD. Non-Watson-Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase. Nucleic Acids Res. 2002 Feb 15; 30(4):950-7. PMID: 11842106.
      View in: PubMed
    156. Tackett AJ, Corey DR, Raney KD. Non-Waston-Crick Interactions between PNA and DNA Inhibits the ATPase Activity of Bacteirophage. Nucleic Acids Res. 2002; 30:950-957.
    157. Morris PD, Byrd AK, Tackett AJ, Cameron CE, Tanega P, Ott R, Fanning E, Raney KD. Hepatitis C Virus NS3 and simian Virus 40 T Antigen Helicases Displace Streptavidin from 5-Biotinylated Oligonucleotides but not from 3-Biotinylated Oligonnucleotides: evidence for directional Bias in Translocation on Single- Stranded DNA. Biochemistry. 2002; 41:2372-2378.
    158. Morris PD, Tackett AJ, Babb K, Nanduri B, Chick C, Scott J, Raney KD. Evidence for a functional Monomeric Form of the Bacteriophage T4 Dda Helicase. J Bio Chem. 2001; 276:19691-19698.
    159. Avaritt NL, Fade M, Reynolds M, Sengupta D, Makhoul I, Shalin S, Tackett AJ. Cutaneous Melanoma: Molecular Mechanisms and Current Therapeutic Approaches.
    Tackett's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (575) concept(s)
    _
    Co-Authors Expand Description
    See all (85) people
    _
    Similar People Expand Description
    See all (34) people
    _
    Same Department Expand Description
    Search Department