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Jason Farrar

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPeds Pediatrics, College of Medicine
DivisionPeds Hematology
Address9-123 Cancer Institute
1120 Marshall Street
Mail Slot # 512-10
Little Rock AR 72202
Phone501-603-1224
ORCID ORCID Icon0000-0003-2148-5839 Additional info
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    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    K12TR004924     (SCHOOTMAN, MARIO)Jul 1, 2024 - Jun 30, 2029
    NIH
    CTSA K12 Program at the University of Arkansas for Medical Sciences
    Role: Co-Principal Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2027
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Principal Investigator
    P20GM121293     (BYRD, ALICIA K)Jul 1, 2022 - Jun 30, 2024
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute
    Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI
    Role: Principal Investigator
    GR039178     (FARRAR, JASON E)Jul 1, 2022 - Jun 30, 2023
    UAMS ACHRI Flow Through
    GR039178-Farrar-ACRI Proteogenomics Core
    Role: Principal Investigator
    GR034151     (FARRAR, JASON E)Feb 1, 2022 - Jan 31, 2023
    UAMS ACHRI Flow Through
    GR034151 Farrar ACHRI Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)
    Role: Principal Investigator
    R01HL150194     (FARRAR, JASON ELI)Feb 15, 2020 - Jan 31, 2024
    NIH
    Mechanisms of Erythroid Remission in Diamond Blackfan Anemia (DBA)
    Role: Principal Investigator
    034032     (FARRAR, JASON E)Feb 15, 2020 - Jan 31, 2023
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    GR034024     (FARRAR, JASON E)Oct 1, 2019 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    R01HD093461     (CHILDS, GWEN V;MACNICOL, ANGUS M ;MACNICOL, MELANIE C)Sep 1, 2018 - Jun 30, 2024
    NIH
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Investigator
    ACRI # 039142     (FARRAR, JASON E)Jul 1, 2018 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#039142     (FARRAR, JASON E)Jul 1, 2018 - Jun 30, 2020
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI # 039143     (FARRAR, JASON E)Apr 1, 2018 - Mar 31, 2019
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    ACRI#039143     (FARRAR, JASON E)Apr 1, 2018 - Mar 31, 2019
    UAMS ACHRI Flow Through
    No FP attached
    Role: Principal Investigator
    5P20 GM121293-03     (FARRAR, JASON E)Jul 1, 2017 - Sep 30, 2019
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Hospital
    Tackett COBRE-SUBAward J Farrar Project 1 - Continuation - Continuation
    Role: Principal Investigator
    5P20GM121293     (FARRAR, JASON E)Jul 1, 2017 - Sep 30, 2019
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Hospital
    Tackett COBRE-SUBAward J Farrar Project 1 - Continuation - Continuation
    Role: Principal Investigator
    R01DK113776     (CHILDS, GWEN V)Apr 1, 2017 - Mar 31, 2021
    NIH
    Tropic Roles for Leptin in the Maturation of Somatotropes
    Role: Co-Investigator
    ACRI #037093     (FARRAR, JASON E)Nov 1, 2016 - Oct 31, 2018
    Arkansas Children's Research Institute
    Integrative Genomics in Pediatric AML
    Role: Principal Investigator
    ACRI#037093     (FARRAR, JASON E)Nov 1, 2016 - Oct 31, 2018
    Arkansas Children's Research Institute
    Integrative Genomics in Pediatric AML
    Role: Principal Investigator
    ACRI # 039704     (FARRAR, JASON E)Jul 1, 2016 - Jun 30, 2017
    UAMS ACHRI Flow Through
    Epigenomic Characterization of Pediatric AML
    Role: Principal Investigator
    ACRI#039704     (FARRAR, JASON E)Jul 1, 2016 - Jun 30, 2017
    UAMS ACHRI Flow Through
    Epigenomic Characterization of Pediatric AML
    Role: Principal Investigator
    0000856528     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    0000881186     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    0000914837     (FARRAR, JASON E)Jul 1, 2015 - Jun 30, 2018
    St. Baldrick's Foundation - Pass Through: Fred Hutchinson Cancer Research Center
    St. Baldrick's Subaward
    Role: Principal Investigator
    K08HL092224     (FARRAR, JASON ELI)Apr 26, 2009 - Mar 31, 2015
    NIH
    Functional Analysis of RPL35A Alterations in Diamond Blackfan Anemia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Lynch SN, Craig M, Michael G, Weatherly J, Swanson JM, Farrar JE, Nouer S, Tolley E, Byerly S, Filiberto DM. Risk Under Pressure: Gastrointestinal Bleeding in Critically Injured Trauma Patients. J Am Coll Surg. 2025 Sep 09. PMID: 40923636.
      View in: PubMed
    2. Adams DS, Conaway BD, Farrar JE, Byerly S, Filiberto DM, Dickerson RN. Evaluation of NPH Insulin Dosing Interval for Critically Ill Hyperglycemic Trauma Patients During Continuous Enteral Nutrition: A Pilot Study. Nutrients. 2025 Sep 05; 17(17). PMID: 40944267.
      View in: PubMed
    3. Higgs ES, Altaf A, Lurie N, Fotouhi A, Kilmarx PH, Nyirenda T, Ogutu B, Rani M, Doumbia S, Sprumont D, van Delden JJM, Sorenson RA, Moorthy V, Farrar J. National research ecosystems: protecting populations and building health security worldwide. Lancet Glob Health. 2025 Sep; 13(9):e1648-e1653. PMID: 40845890.
      View in: PubMed
    4. Harmon LM, Hattig ZS, Huang YP, Beckford C, Farrar J, Pollard JA, Zarnegar-Lumley S, Ma X, Ries RE, Meshinchi S, Godley LA, Triche TJ. Germline Variant Burden Warrants Universal Genetic Testing in Pediatric Myeloid Leukemia. medRxiv. 2025 Jul 30. PMID: 40766138.
      View in: PubMed
    5. Livingston JN, Harlan SS, Yaranov DM, Farrar JE. Enteral Feeding Tube Administration of Oral Sirolimus Tablets in a Critically Ill Adult. J Pharm Pract. 2025 Jul 28; 8971900251364068. PMID: 40719401.
      View in: PubMed
    6. Moorthy V, Devereaux PJ, Sui-Lin Teh C, Rooslamiati I, Adeyemi OD, Hamid S, Zanoletty A, Nyarko K, Zhang W, Farrar J, Abubakar I. Tracking maturity of the enabling environment for clinical trials. Lancet. 2025 Jul 12; 406(10499):113-116. PMID: 40609558.
      View in: PubMed
    7. Dickerson RN, Adams DS, Farrar JE, Swanson JM, Soule S, Byerly S, Filiberto DM, Hudson JQ. Estimating measured creatinine clearance for critically ill trauma patients with presumed normal kidney function. Am J Health Syst Pharm. 2025 May 23; 82(11):e498-e506. PMID: 39910967.
      View in: PubMed
    8. Reed HD, Do H, Weller E, Harris MH, Reilly CR, Tsai HK, Farrar JE, Lau BW, Pommert L, Gamper C, Atkinson I, Coyne K, Joos M, Loveless S, Steltz S, Cheng L, Malsch M, Myers K, Shimamura A. Lymphoid malignancies in patients with Shwachman-Diamond syndrome. Blood. 2025 May 22; 145(21):2528-2532. PMID: 40090004.
      View in: PubMed
    9. Shimamura A, Maschan A, Bennett C, Samarasinghe S, Farrar JE, Li CK, Sirachainan N, Pongtanakul B, Komvilaisak P, Zubarovskaya L, Rothman JA, Walkovich K, Nakano TA, Bertuch AA, Ferrao A, Bhat R, Hanna R, Overholt KM, Boklan J, Wong TF, Wang Q, Urban P, Strahm B, Wang W, Vlachos A, Williams DA. Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: Phase 2 ESCALATE trial. Blood Adv. 2025 May 02. PMID: 40315366.
      View in: PubMed
    10. Olaghere J, Williams DA, Farrar J, B?ning H, Calhoun C, Ho T, Inamdar MS, Liu D, Makani J, Nyarko K, Ruiz S, Tisdale J, McCune JM, Boadi E. Scientific Advancements in Gene Therapies: Opportunities for Global Regulatory Convergence. Biomedicines. 2025 Mar 20; 13(3). PMID: 40149734.
      View in: PubMed
    11. Kerwin AJ, Wood GC, Byerly S, Filiberto DM, Farrar JE, Swanson JM, Rogers ML, Croce MA. Antibiogram Surveillance to Determine Appropriate Initial Empiric Antibiotic Therapy for Ventilator-Associated Pneumonia. Surg Infect (Larchmt). 2025 Feb 24. PMID: 39989087.
      View in: PubMed
    12. Swanson JM, Cole PC, Farrar JE, Smith KL, Kerwin AJ, Wood GC, Filiberto DM. Comparison of Multi-Drug Resistant Organisms Causing Early Ventilator-Associated Pneumonia in Three Geographically Distinct Trauma Intensive Care Units. Surg Infect (Larchmt). 2025 Jun; 26(5):324-330. PMID: 39815822.
      View in: PubMed
    13. Liu Z, Tsai T, Zuo B, Howe S, Farrar JE, Randolph CE, Maxwell CV, Zhao J. The sow vaginal and gut microbiota associated with longevity and reproductive performance. J Anim Sci Biotechnol. 2025 Jan 07; 16(1):6. PMID: 39762999.
      View in: PubMed
    14. Dickerson RN, McLeod AR, Stonecipher AE, Farrar JE, Byerly S, Filiberto DM, Fischer PE. Outpatient diabetes management influences glycemic control for critically ill patients during nutrition support: A retrospective observational study. Nutr Clin Pract. 2025 Feb; 40(1):134-146. PMID: 39584749.
      View in: PubMed
    15. Farrar JE, Stefanos SS, Cava L, Kiser TH, Mueller SW, Neumann R, Reynolds PM, Sherman DS, MacLaren R. Correlation Between Serum and CSF Concentrations of Midazolam and 1-Hydroxy-Midazolam in Critically Ill Neurosurgical Patients. Ann Pharmacother. 2025 Mar; 59(3):244-249. PMID: 39164827.
      View in: PubMed
    16. Saad-Roy CM, Morris SE, Boots M, Baker RE, Lewis BL, Farrar J, Marathe MV, Graham AL, Levin SA, Wagner CE, Metcalf CJE, Grenfell BT. Impact of waning immunity against SARS-CoV-2 severity exacerbated by vaccine hesitancy. PLoS Comput Biol. 2024 Aug; 20(8):e1012211. PMID: 39102402.
      View in: PubMed
    17. Doan DT, Strebeck PV, Tran AD, Farrar JE, Appell LE, Modi AJ, Jefferson AA. Evaluation of recurrent and recalcitrant warts in a deaf adolescent male reveals GATA2 deficiency. J Allergy Clin Immunol Glob. 2024 Nov; 3(4):100313. PMID: 39221430.
      View in: PubMed
    18. Wlodarski MW, Vlachos A, Farrar JE, Da Costa LM, Kattamis A, Dianzani I, Belendez C, Unal S, Tamary H, Pasauliene R, Pospisilova D, de la Fuente J, Iskander D, Wolfe L, Liu JM, Shimamura A, Albrecht K, Lausen B, Bechensteen AG, Tedgard U, Puzik A, Quarello P, Ramenghi U, Bartels M, Hengartner H, Farah RA, Al Saleh M, Hamidieh AA, Yang W, Ito E, Kook H, Ovsyannikova G, Kager L, Gleizes PE, Dalle JH, Strahm B, Niemeyer CM, Lipton JM, Leblanc TM. Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement. Lancet Haematol. 2024 May; 11(5):e368-e382. PMID: 38697731.
      View in: PubMed
    19. Abla O, Ries RE, Triche T, Gerbing RB, Hirsch B, Raimondi S, Cooper T, Farrar JE, Buteyn N, Harmon LM, Wen H, Deshpande AJ, Kolb EA, Gamis AS, Aplenc R, Alonzo T, Meshinchi S. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia. Blood Adv. 2024 04 23; 8(8):2005-2017. PMID: 38306602.
      View in: PubMed
    20. Appell LE, Mack JM, Farrar JE, Roper SN, Savage MR, Pandey S, Crary SE. Acquired Hemophilia: A Rare Complication of Pediatric Idiopathic Multicentric Castleman Disease. Pediatrics. 2024 Apr 01; 153(4). PMID: 38511235.
      View in: PubMed
    21. Frett B, Stephens KE, Koss B, Melnyk S, Farrar J, Saha D, Roy Choudhury S. Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia. Cancer Sci. 2024 Mar; 115(3):963-973. PMID: 38226414.
      View in: PubMed
    22. Saad-Roy CM, Morris SE, Baker RE, Farrar J, Graham AL, Levin SA, Wagner CE, Metcalf CJE, Grenfell BT. Medium-term scenarios of COVID-19 as a function of immune uncertainties and chronic disease. J R Soc Interface. 2023 08; 20(205):20230247. PMID: 37643641.
      View in: PubMed
    23. Bertrums EJM, Smith JL, Harmon L, Ries RE, Wang YJ, Alonzo TA, Menssen AJ, Chisholm KM, Leonti AR, Tarlock K, Ostronoff F, Pogosova-Agadjanyan EL, Kaspers GJL, Hasle H, Dworzak M, Walter C, Muhlegger N, Morerio C, Pardo L, Hirsch B, Raimondi S, Cooper TM, Aplenc R, Gamis AS, Kolb EA, Farrar JE, Stirewalt D, Ma X, Shaw TI, Furlan SN, Brodersen LE, Loken MR, Van den Heuvel-Eibrink MM, Zwaan CM, Triche TJ, Goemans BF, Meshinchi S. Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia. Haematologica. 2023 08 01; 108(8):2044-2058. PMID: 36815378.
      View in: PubMed
    24. Sun JM, Chow WY, Xu G, Hicks MJ, Nakka M, Shen J, Ng PKS, Taylor AM, Yu A, Farrar JE, Barkauskas DA, Gorlick R, Guidry Auvil JM, Gerhard D, Meltzer P, Guerra R, Man TK, Lau CC. The Role of FAS Receptor Methylation in Osteosarcoma Metastasis. Int J Mol Sci. 2023 Jul 29; 24(15). PMID: 37569529.
      View in: PubMed
    25. Dickerson RN, Farrar JE, Byerly S, Filiberto DM. Enteral feeding tolerance during pharmacologic neuromuscular blockade. Nutr Clin Pract. 2023 Dec; 38(6):1236-1246. PMID: 37475530.
      View in: PubMed
    26. Farrar JE, Othus M, Wang YC, Alonzo TA, Meshinchi S. Reply to Z.R. McCaw et al. J Clin Oncol. 2023 09 20; 41(27):4447. PMID: 37390387.
      View in: PubMed
    27. Buckley CT, Farrar JE, Schleicher M, Stollings JL, Duggal A, Bauer SR. Physical and Chemical Compatibility of Medications Commonly Used in Critically Ill Patients With Balanced Crystalloids: A Systematic Review. Ann Pharmacother. 2024 Mar; 58(3):322-332. PMID: 37340978.
      View in: PubMed
    28. Farrar JE, Smith JL, Othus M, Huang BJ, Wang YC, Ries R, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti A, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2023 06 01; 41(16):2949-2962. PMID: 36795987.
      View in: PubMed
    29. Baker RE, Saad-Roy CM, Park SW, Farrar J, Metcalf CJE, Grenfell BT. Long-term benefits of nonpharmaceutical interventions for endemic infections are shaped by respiratory pathogen dynamics. Proc Natl Acad Sci U S A. 2022 12 06; 119(49):e2208895119. PMID: 36445971.
      View in: PubMed
    30. Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 09 19; 13(1):5487. PMID: 36123353.
      View in: PubMed
    31. Farrar JE, Mueller SW, Stevens V, Kiser TH, Taleb S, Reynolds PM. Correlation of antimicrobial fraction unbound and sieving coefficient in critically ill patients on continuous renal replacement therapy: a systematic review. J Antimicrob Chemother. 2022 02 02; 77(2):310-319. PMID: 35107138.
      View in: PubMed
    32. Hu Y, Caldwell KJ, Onciu M, Federico SM, Salek M, Lewis S, Lei S, Zhang J, Nichols KE, Takemoto CM, Triplett BM, Farrar JE, Rubnitz JE, Ribeiro RC, Wlodarski MW. CPX-351 induces remission in newly diagnosed pediatric secondary myeloid malignancies. Blood Adv. 2022 01 25; 6(2):521-527. PMID: 34710216.
      View in: PubMed
    33. Hecht A, Meyer JA, Behnert A, Wong E, Chehab F, Olshen A, Hechmer A, Aftandilian C, Bhat R, Choi SW, Chonat S, Farrar JE, Fluchel M, Frangoul H, Han JH, Kolb EA, Kuo DJ, MacMillan ML, Maese L, Maloney KW, Narendran A, Oshrine B, Schultz KR, Sulis ML, Van Mater D, Tasian SK, Hofmann WK, Loh ML, Stieglitz E. Molecular and phenotypic diversity of CBL-mutated juvenile myelomonocytic leukemia. Haematologica. 2022 01 01; 107(1):178-186. PMID: 33375775.
      View in: PubMed
    34. Huang BJ, Smith JL, Wang YC, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing R, Crowgey E, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche T, Alonzo TA, Ma X, Meshinchi S. CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes. Blood Adv. 2021 12 14; 5(23):4963-4968. PMID: 34547772.
      View in: PubMed
    35. Pritchard E, Jones J, Vihta KD, Stoesser N, Matthews PPC, Eyre DW, House T, Bell JI, Newton PJN, Farrar J, Crook PD, Hopkins S, Cook D, Rourke E, Studley R, Diamond PI, Peto PT, Pouwels KB, Walker PAS. Monitoring populations at increased risk for SARS-CoV-2 infection in the community using population-level demographic and behavioural surveillance. Lancet Reg Health Eur. 2022 Feb; 13:100282. PMID: 34927119.
      View in: PubMed
    36. Bolouri H, Ries R, Pardo L, Hylkema T, Zhou W, Smith JL, Leonti A, Loken M, Farrar JE, Triche TJ, Meshinchi S. A B-cell developmental gene regulatory network is activated in infant AML. PLoS One. 2021; 16(11):e0259197. PMID: 34793513.
      View in: PubMed
    37. Douglass DP, Stine KC, Farrar JE. A Novel Germline TP53 Mutation in a Patient With Li-Fraumeni Syndrome: Resolving a Variant of Uncertain Significance. J Pediatr Hematol Oncol. 2021 Nov 01; 43(8):e1220-e1222. PMID: 33633026.
      View in: PubMed
    38. Wagner CE, Saad-Roy CM, Morris SE, Baker RE, Mina MJ, Farrar J, Holmes EC, Pybus OG, Graham AL, Emanuel EJ, Levin SA, Metcalf CJE, Grenfell BT. Vaccine nationalism and the dynamics and control of SARS-CoV-2. Science. 2021 Sep 24; 373(6562):eabj7364. PMID: 34404735.
      View in: PubMed
    39. Farrar JE, Trujillo TC, Mueller SW, Beltran L, Nguyen C, Hassell K, Kiser TH. Evaluation of a patient specific, targeted-intensity pharmacologic thromboprophylaxis protocol in hospitalized patients with COVID-19. J Thromb Thrombolysis. 2022 Feb; 53(2):446-453. PMID: 34410561.
      View in: PubMed
    40. Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarrag? T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B. Publisher Correction: Voices of biotech leaders. Nat Biotechnol. 2021 Aug; 39(8):1017. PMID: 34290438.
      View in: PubMed
    41. Walker AS, Pritchard E, House T, Robotham JV, Birrell PJ, Bell I, Bell JI, Newton JN, Farrar J, Diamond I, Studley R, Hay J, Vihta KD, Peto TE, Stoesser N, Matthews PC, Eyre DW, Pouwels KB. Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time. Elife. 2021 07 12; 10. PMID: 34250907.
      View in: PubMed
    42. Calisher CH, Carroll D, Colwell R, Corley RB, Daszak P, Drosten C, Enjuanes L, Farrar J, Field H, Golding J, Gorbalenya AE, Haagmans B, Hughes JM, Keusch GT, Lam SK, Lubroth J, Mackenzie JS, Madoff L, Mazet JK, Perlman SM, Poon L, Saif L, Subbarao K, Turner M. Science, not speculation, is essential to determine how SARS-CoV-2 reached humans. Lancet. 2021 07 17; 398(10296):209-211. PMID: 34237296.
      View in: PubMed
    43. Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarrag? T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B. Voices of biotech leaders. Nat Biotechnol. 2021 06; 39(6):654-660. PMID: 34113035.
      View in: PubMed
    44. Gill PS, Yu FB, Porter-Gill PA, Boyanton BL, Allen JC, Farrar JE, Veerapandiyan A, Prodhan P, Bielamowicz KJ, Sellars E, Burrow A, Kennedy JL, Clothier JL, Becton DL, Rule D, Schaefer GB. Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children's Hospital. J Pers Med. 2021 May 11; 11(5). PMID: 34064668.
      View in: PubMed
    45. Gianferante MD, Wlodarski MW, Atsidaftos E, Da Costa L, Delaporta P, Farrar JE, Goldman FD, Hussain M, Kattamis A, Leblanc T, Lipton JM, Niemeyer CM, Pospisilova D, Quarello P, Ramenghi U, Sankaran VG, Vlachos A, Volejnikova J, Alter BP, Savage SA, Giri N. Genotype-phenotype association and variant characterization in Diamond-Blackfan anemia caused by pathogenic variants in RPL35A. Haematologica. 2021 05 01; 106(5):1303-1310. PMID: 32241839.
      View in: PubMed
    46. Saad-Roy CM, Morris SE, Metcalf CJE, Mina MJ, Baker RE, Farrar J, Holmes EC, Pybus OG, Graham AL, Levin SA, Grenfell BT, Wagner CE. Partial immunity and SARS-CoV-2 mutations-Response. Science. 2021 04 23; 372(6540):354-355. PMID: 33888633.
      View in: PubMed
    47. Farrar JE, Droege ME, Philpott CD, Mueller EW, Ernst NE, Makley AT, Deichstetter KM, Droege CA. Impact of Weight on Anti-Xa Attainment in High-Risk Trauma Patients on Enoxaparin Chemoprophylaxis. J Surg Res. 2021 08; 264:425-434. PMID: 33848842.
      View in: PubMed
    48. Park SW, Pons-Salort M, Messacar K, Cook C, Meyers L, Farrar J, Grenfell BT. Epidemiological dynamics of enterovirus D68 in the United States and implications for acute flaccid myelitis. Sci Transl Med. 2021 03 10; 13(584). PMID: 33692131.
      View in: PubMed
    49. Saad-Roy CM, Morris SE, Metcalf CJE, Mina MJ, Baker RE, Farrar J, Holmes EC, Pybus OG, Graham AL, Levin SA, Grenfell BT, Wagner CE. Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes. Science. 2021 04 23; 372(6540):363-370. PMID: 33688062.
      View in: PubMed
    50. Li J, Galbo PM, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. Nat Commun. 2021 02 16; 12(1):1045. PMID: 33594072.
      View in: PubMed
    51. Saad-Roy CM, Morris SE, Metcalf CJE, Mina MJ, Baker RE, Farrar J, Holmes EC, Pybus OG, Graham AL, Levin SA, Grenfell BT, Wagner CE. Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes. medRxiv. 2021 Feb 03. PMID: 33564785.
      View in: PubMed
    52. Park SW, Farrar J, Messacar K, Meyers L, Pons-Salort M, Grenfell BT. Epidemiological dynamics of enterovirus D68 in the US: implications for acute flaccid myelitis. medRxiv. 2021 Jan 28. PMID: 32766605.
      View in: PubMed
    53. Phu NH, Day NPJ, Tuan PQ, Mai NTH, Chau TTH, Van Chuong L, Vinh H, Loc PP, Sinh DX, Hoa NTT, Waller DJ, Wain J, Jeyapant A, Watson JA, Farrar JJ, Hien TT, Parry CM, White NJ. Concomitant Bacteremia in Adults With Severe Falciparum Malaria. Clin Infect Dis. 2020 12 03; 71(9):e465-e470. PMID: 32107527.
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    111. Ochs MF, Farrar JE, Considine M, Wei Y, Meschinchi S, Arceci RJ. Outlier Gene Set Analysis Combined with Top Scoring Pair Provides Robust Biomarkers of Pathway Activity. 8th IAPR International Conference on Pattern Recognition in Bioinformatics. 2013.
    112. Vlachos A, Farrar JE, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis SR, Arceci RJ, Bodine D, Lipton J. 5q Myelodysplastic Syndrome (MDS) Masquerading as Diamond Blackfan Anemia [Abstract]. 25th Annual Meeting of the American Society of Pediatric Hematology Oncology. 2012; 1074.
    113. Markello TC, Carlson-Donohoe H, Sincan M, Adams D, Bodine DM, Farrar JE, Vlachos A, Lipton JM, Auerbach AD, Ostrander EA, Chandrasekharappa SC, Boerkoel CF, Gahl WA. Sensitive quantification of mosaicism using high density SNP arrays and the cumulative distribution function. Mol Genet Metab. 2012 Apr; 105(4):665-71. PMID: 22277120.
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    114. Farrar JE, Vlachos A, Atsidaftos E, Carlson-Donohoe H, Markello TC, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. Ribosomal protein gene deletions in Diamond-Blackfan anemia. Blood. 2011 Dec 22; 118(26):6943-51. PMID: 22045982.
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    115. Farrar JE, Dahl N. Untangling the phenotypic heterogeneity of Diamond Blackfan anemia. Semin Hematol. 2011 Apr; 48(2):124-35. PMID: 21435509.
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    116. Day JN, Hoang TN, Duong AV, Hong CT, Diep PT, Campbell JI, Sieu TP, Hien TT, Bui T, Boni MF, Lalloo DG, Carter D, Baker S, Farrar JJ. Most cases of cryptococcal meningitis in HIV-uninfected patients in Vietnam are due to a distinct amplified fragment length polymorphism-defined cluster of Cryptococcus neoformans var. grubii VN1. J Clin Microbiol. 2011 Feb; 49(2):658-64. PMID: 21159929.
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    117. Farrar JE, Vlachos A, Atsidaftos EA, Carlson-Donohoe H, Markello TC, Arceci RJ, Lipton JM, Bodine DM. SNP Array Genotyping Reveals Constitutional and Mosaic Losses of Ribosomal Protein Gene Regions In Patients with Diamond Blackfan Anemia without Ribosomal Protein Gene Mutations [Abstract]. American Society of Hematology Annual Meeting. 2010.
    118. Vlachos A, Farrar J, Atsidaftos E, Muir E, Markello TC, Singh S, Liu JM, Ellis S, Arceci RJ, Bodine DM, Lipton JM. 5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide [Abstract]. American Society of Hematology Annual Meeting. 2010.
    119. Le VT, Phan TQ, Do QH, Nguyen BH, Lam QB, Bach V, Truong H, Tran TH, Nguyen V, Tran T, Vo M, Tran VT, Schultsz C, Farrar J, van Doorn HR, de Jong MD. Viral etiology of encephalitis in children in southern Vietnam: results of a one-year prospective descriptive study. PLoS Negl Trop Dis. 2010 Oct 26; 4(10):e854. PMID: 21049060.
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    120. Chau TT, Mai NH, Phu NH, Nghia HD, Chuong LV, Sinh DX, Duong VA, Diep PT, Campbell JI, Baker S, Hien TT, Lalloo DG, Farrar JJ, Day JN. A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease. BMC Infect Dis. 2010 Jul 09; 10:199. PMID: 20618932.
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    121. Holt KE, Baker S, Dongol S, Basnyat B, Adhikari N, Thorson S, Pulickal AS, Song Y, Parkhill J, Farrar JJ, Murdoch DR, Kelly DF, Pollard AJ, Dougan G. High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children. BMC Infect Dis. 2010 May 31; 10:144. PMID: 20509974.
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    122. Tricou V, Vu HT, Quynh NV, Nguyen CV, Tran HT, Farrar J, Wills B, Simmons CP. Comparison of two dengue NS1 rapid tests for sensitivity, specificity and relationship to viraemia and antibody responses. BMC Infect Dis. 2010 May 28; 10:142. PMID: 20509940.
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    123. Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE, Gazda HT. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010 Feb 12; 86(2):222-8. PMID: 20116044.
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    124. Moore JB, Farrar JE, Arceci RJ, Liu JM, Ellis SR. Distinct Ribosome Maturation Defects in Yeast Models for Diamond Blackfan Anemia and Shwachman Diamond Syndrome. Haematologica. 2010; 95(1):57-64.
    125. Noronha SA, Farrar JE, Alonzo TA, Gerbing RB, Lacayo NJ, Dahl GV, Ravindranath Y, Arceci RJ, Loeb DM. WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009 Dec; 53(6):1136-9. PMID: 19618455.
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    126. Heuston EF, Farrar JE, Triche T, Buckley J, Sorensen P, Reynolds P, Reaman G, Yegnasubramanian V, Arceci RA. Selective and Titratable Effects On AML Genome-wide Methylation Patterning, Transcription, and Clonogenicity Using Low Concentrations of 5-Aza-2’ Deoxycytidine [Abstract]. American Society of Hematology Annual Meeting. 2009.
    127. Moore JB, Farrar JE, Arceci RJ, Liu JM, Ellis SR. Distinct ribosome maturation defects in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome. Haematologica. 2010 Jan; 95(1):57-64. PMID: 19713223.
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    128. Minh Vien LT, Baker S, Phuong Thao LT, Phuong Tu LT, Thu Thuy C, Thu Nga TT, Minh Hoang NV, Campbell JI, Minh Yen L, Trong Hieu N, Vinh Chau NV, Farrar J, Schultsz C. High prevalence of plasmid-mediated quinolone resistance determinants in commensal members of the Enterobacteriaceae in Ho Chi Minh City, Vietnam. J Med Microbiol. 2009 Dec; 58(Pt 12):1585-1592. PMID: 19696153.
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    129. Suzuki T, Farrar JE, Yegnasubramanian S, Zahed M, Suzuki N, Arceci RJ. Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts. Epigenetics. 2008 Sep; 3(5):281-91. PMID: 18948754.
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    130. Tan LV, Ha DQ, Hien VM, van der Hoek L, Farrar J, de Jong MD. Me Tri virus: a Semliki Forest virus strain from Vietnam? J Gen Virol. 2008 Sep; 89(Pt 9):2132-2135. PMID: 18753222.
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    131. Farrar JE, Nater M, Caywood E, McDevitt MA, Kowalski J, Takemoto CM, Talbot CC, Meltzer P, Esposito D, Beggs AH, Schneider HE, Grabowska A, Ball SE, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Ellis SR, Lipton JM, Gazda HT, Arceci RJ. Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia. Blood. 2008 Sep 01; 112(5):1582-92. PMID: 18535205.
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    132. Farrar J, Nater M, Caywood EH, McDevitt M, Kowalski J, Takemoto CM, Meltzer P, Beggs AH, Schneider HA, Grabowska A, Ball S, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Lipton JM, Gazda HT, Arceci RA. A Large Subunit Abnormality in Diamond-Blackfan Anemia (DBA) [Abstract]. American Society of Hematology Annual Meeting. 2007; 422.
    133. Zhang L, Anglesio MS, O'Sullivan M, Zhang F, Yang G, Sarao R, Mai PN, Cronin S, Hara H, Melnyk N, Li L, Wada T, Liu PP, Farrar J, Arceci RJ, Sorensen PH, Penninger JM. The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers. Nat Med. 2007 Sep; 13(9):1060-9. PMID: 17694067.
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    134. Sch?nemann HJ, Hill SR, Kakad M, Vist GE, Bellamy R, Stockman L, Wisl?ff TF, Del Mar C, Hayden F, Uyeki TM, Farrar J, Yazdanpanah Y, Zucker H, Beigel J, Chotpitayasunondh T, Hien TT, Ozbay B, Sugaya N, Oxman AD. Transparent development of the WHO rapid advice guidelines. PLoS Med. 2007 May; 4(5):e119. PMID: 17535099.
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    135. Sch?nemann HJ, Hill SR, Kakad M, Bellamy R, Uyeki TM, Hayden FG, Yazdanpanah Y, Beigel J, Chotpitayasunondh T, Del Mar C, Farrar J, Tran TH, Ozbay B, Sugaya N, Fukuda K, Shindo N, Stockman L, Vist GE, Croisier A, Nagjdaliyev A, Roth C, Thomson G, Zucker H, Oxman AD. WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus. Lancet Infect Dis. 2007 Jan; 7(1):21-31. PMID: 17182341.
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    136. Hawn TR, Dunstan SJ, Thwaites GE, Simmons CP, Thuong NT, Lan NTN, Quy HT, Chau TTH, Hieu NT, Rodrigues S, Janer M, Zhao LP, Hien TT, Farrar JJ, Aderem A. A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis. J Infect Dis. 2006 Oct 15; 194(8):1127-1134. PMID: 16991088.
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    137. Neuman DL, Farrar JE, Moresi JM, Vogelsang GB, Higman MA. Toxic absorption of tacrolimus [corrected] in a patient with severe acute graft-versus-host disease. Bone Marrow Transplant. 2005 Nov; 36(10):919-20. PMID: 16151424.
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    138. Farrar JE, Rohrer J, Conley ME. Neutropenia in X-linked agammaglobulinemia. Clin Immunol Immunopathol. 1996 Dec; 81(3):271-6. PMID: 8938104.
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    139. Moore JB, Farrar JE, Arceci RA, Liu J, Ellis SR. Yeast Models for Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ In Their Effect On Translation of Certain Classes of mRNA [Abstract].
    140. Williams D, Coates T, Shimamura A, Arceci RJ, Bennett C, Bertuch A, Bessler M, Chawla A, Corey SJ, Dror Y, Farrar J, Glader B, Hartung H, Hofmann I, Huang J, Kurre P, Lehmann L, Lipton J, Olson T, Reiss U, Rogers Z, Sieff C, Takemoto C, Vlachos A, Walkovich K, Wang W. Diagnosis and Treatment of Pediatric Acquired Aplastic Anemia (AAA): An Initial Study of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer, 60; S1-105.
    141. Meshinchi S, Ries RE, Farrar JE, Guidry Auvil J, Davidsen TM, Gesuwan P, Trevino LR, Muzny DM, Wheeler DA, Gamis AS, Alonzo TA, Smith MA, Gerhard DS, Arceci RJ. Demonstration of Significant Clonal Evolution from Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing - An NCI/COG TARGET AML Study [Abstract].
    142. Farrar JE, Gazda HT, Beggs AH, Atsidaftos E, Arceci RA, Lipton JM, Vlachos A. Sequence Abnormalities In Genes Encoding Ribosomal Proteins In Patients With Diamond Blackfan Anemia: A Preliminary Report from the Resequencing Project [Abstract].
    143. Meshinchi S, Ries RE, Trevino LR, Hampton OA, Alonzo TA, Farrar JE, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Helton HL, Wheeler DA, Smith MA, Gerhard DS, Arceci RJ. Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution from Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing – An NCI/COG TARGET AML Study. American Society of Hematology Annual Meeting.
    144. Ellis SR, Moore JB, Pavesi E, Dianzani I, Farrar J, Arceci RJ, Vlachos A, Lipton JM, Liu JM. Diamond Blackfan anemia: What’s the 5S ribonucleoprotein subcomplex got to do with it? [Abstract].
    145. Caywood E, Farrar JE, Lipton JM, Arceci RJ. Differential Down-Regulation of RPL35a in Human Bone Marrow Progenitors Demonstrates a p53 Independent Mechanism Mediating the Diamond Blackfan Anemia Phenotype [Abstract]. American Society of Hematology Annual Meeting. 1096.
    146. Mendoza-Naranjo A, Wai DH, Farrar JE, Zhu Q, Mistry P, Lazic N, Ayala FRR, Da Cunha IW, Arceci RJ, Soares FA, Triche TJ, Strauss SJ, Sorensen PJ. ErbB4 is a Novel Driver of Metastasis and Anoikis Resistance in Ewing’s Sarcoma [Abstract].
    147. Fisher R, Henson AL, Quarello P, Aspesi A, Farrar JE, Arceci RJ, Bodine DM, Dianzani I, Lipton JM, Ramenghi U, Vlachos A, Ellis SR. Insights into diagnosis and etiology of Diamond Blackfan anemia by analysis of pre-rRNA processing [Abstract]. American Society of Hematology Annual Meeting.
    148. Farrar JE, Nater M, Caywood EH, McDevitt M, Kowalski J, Takemoto CM, Meltzer P, Beggs AH, Schneider HA, Grabowska A, Ball S, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Lipton JM, Gazda HT, Arceci RA. A Large Subunit Abnormality in DBA [Abstract].
    149. Osorio DS, Atsidaftos E, Muir E, Seiden H, Gruber D, Farrar JE, Ellis SR, Glader B, Lipton JM, Vlachos A. Prevalence of Elevated Erythrocyte Adenosine Deaminase (eADA) Activity, A Marker of Diamond Blackfan Anemia (DBA), In Patients with Congenital Heart Disease (CHD). Pediatr Blood Cancer, 60; S1-105.
    150. Ochs MF, Farrar JE, Considine M, Ries R, Trevino LR, Alonzo TA, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Helton HL, Wheeler DA, Smith MA, Gerhard DS, Meshinchi S, Arceci RJ. Genome wide promoter methylation patterns predict AML subtype outcomes and identify novel pathways characterizing diagnostic and relapsed disease in children [Abstract]. American Society of Hematology Annual Meeting.
    151. Vlachos A, Atsidaftos E, Arceci RJ, Ellis SR, Lipton JM, Bodine DM. The Frequent Identification of Ribosomal Protein Gene Deletions in Diamond Blackfan Anemia Patients without Detectable Ribosomal Protein Gene Mutations [Abstract].
    152. Caywood EH, Farrar JE, Lipton JM, Arceci RJ. Differential down-regulation of RPL35a in human bone marrow progenitors demonstrates a p53 independent mechanism mediating the Diamond Blackfan anemia phenotype.
    153. Heuston EF, Farrar JE, Triche T, Buckley J, Wai DH, Ochs M, Considine M, Reaman G, Arceci RJ. 5-Aza-2’-deoxycytidine and Cytarabine Mediate Distinct Effects on Clonogenic Growth, Genome-Wide Methylation and RNA Expression in AML [Abstract].
    154. Helton HL, Ries RE, Alonzo TA, Gerbing RB, Trevino LR, Farrar JE, Guidry-Auvil J, Davidsen TM, Gesuwan P, Muzny DM, Gamis AS, Franklin J, Wheeler DA, Smith MA, Gerhard DS, Arceci RJ, Meshinchi S. Clinically Significant Mutations, Deletions and Translocations involving ETV6 Identified by Whole Genome and Whole Exome Sequencing: a Report from NCI/COG TARGET AML Initiative [Abstract] 54th Annual ASH Meeting, Atlanta, GA. American Society of Hematology Annual Meeting.
    155. Arceci RA, Caywood E, Farrar JE, Nater M, Lipton JM. Down-regulation of Rpl35a and Rps19 in the UT-7/Epo Cell Line Results in Cell Cycle Arrest at G2/M [Abstract].
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