Header Logo
Keywords
Last Name
Institution
Announcement

You can now add alternative names! Click here to add other names that you've published under.

Kalpana Padala

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentGeriatrics, College of Medicine
DivisionGeriatrics Faculty
Address VA 3J NLR
4301 W Markham St.
Mail Slot # 748
Little Rock AR 72205
Phone501-526-6800
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    I have thirteen years of experience in conducting treatment trials in frail elderly. I have focused on alternate modalities to promote exercise in elderly. To overcome various barriers for exercise, I conducted a series of studies investigating the feasibility and efficacy of Nintendo Wii-Fit on gait, and balance in various settings funded by the Alzheimer’s Association and the Department of Veterans Affairs. Later I focused on exercise adherence and ways to improve the same. My current study funded by the RR&D Merit grant is studying the efficacy and lasting effects of repetitive transcranial magnetic stimulation on executive function, exercise performance, self-efficacy and adherence to an adequately dosed, targeted Wii-Fit. The goal of the project is to improve various components of balance in sedentary older Veterans using engaging exercise programs in their home setting.

    Clinically, I evaluate patients in the multidisciplinary memory clinic at the VA. I also lead the comprehensive physical activity promotion clinic, The Geriatric Walking Clinic that I started in 2013. Over 800 Veterans and caregivers have participated in the program and the clinic provides us a naturalistic experiment to study the impact of COVID-19 restrictions on exercise adherence and executive function in older Veterans. Anecdotally, I see the impact of these restrictions on my clinic patients on a daily basis. I also see the struggles of older Veterans in transitioning to telehealth.


    Collapse Affiliation 
    Collapse clinical activities
    Director, Gait and Balance Laboratory, CAVHS, Little Rock, AR
    Director, Geriatric Walking Clinic, CAVHS, Little Rock, AR

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Associate Director for Clinical Research, VISN 16 GRECC

    Collapse awards and honors
    2020Phenomenal Women Award, UAMS
    2020GRECC Clinical Star Award, CAVHS
    2019Academic Excellence Award, American Association of Physician of India origin (AAPI) Arkansas
    2019American Geriatrics Society Fellow (AGSF), American Geriatrics Society
    2019Physician Recognition Award, CAVHS
    2018Director’s Certificate of Recognition for exemplified exceptional service, CAVHS GRECC
    2018Gold Status Fellow – National Award , VHA Diffusion of Excellence for Health’s Promising Practices Consortium
    20181st place, Outstanding Posters and Presentations, 10th Annual Meeting of the American Association of Physicians of Indian Origin, Arkansas Chapter
    2017Director’s Certificate of Recognition for exemplified exceptional service, CAVHS GRECC
    2011American Geriatrics Society/ Merck 2011 New Investigator Award, American Geriatrics Society
    2011Vada Kinman - Oldfield Alzheimer’s Research Scholarship Fund Award, Kinman Oldfield Family Foundation
    2010Best Teacher Award, Department of Family Medicine, University of Nebraska Medical Center
    2009AMDA Foundation/Pfizer Quality Improvement Research Award, American Medical Director’s Association
    2008Travel Fellowship, New Investigators Technical Assistance Workshop, NIMH Health and Behavioral Research
    2007Nancy and Ronald Reagan Alzheimer’s Research Scholarship Fund Award, Kinman Oldfield Family Foundation
    2007Tracy Osborne Award, Nebraska Medical Director’s Association (NMDA)
    2006Futures Award, American Medical Director’s Association (AMDA)
    2006Kashinath Patil Award, Excellence in Research/Scholarly Activity, Department of Family Medicine, University of Nebraska Medical Center

    Collapse Research 
    Collapse research activities and funding
         (Prasad Padala, MD)Aug 16, 2021 - Aug 15, 2023
    Cerevel Therapeutics, LLC
    A Randomized, Double-Blind, Placebo-Controlled Trial To Evaluate The Safety, Tolerability, And Pharmacodynamics Of CVL-871 In Subjects With Dementia-Related Apathy
    Role: Co-Investigator

         (A’mie Preston, PsyD)Aug 1, 2021 - Jul 31, 2023
    VA ORD RRD – Diversity Supplement
    Immersive Virtual Reality for Apathy associated with Cognitive Impairment.
    Role Description: Role: Co-Mentor
    Role: Other

         (PADALA, KALPANA)Oct 1, 2020 - Dec 31, 2022
    Janssen Vaccines & Prevention B.V.
    A Randomized, Double-blind, Placebo-controlled Phase 3 Study to assess the Efficacy and Safety of Ad26COVS1 for the Prevention of SARS-CoV-2 mediated COVID-19 in Adults Aged 18 Years and Older
    Role Description: The study will test the efficacy and safety of Ad26COVS1 for the prevention of SARS-CoV-2 mediated COVID-19 in adults aged 18 years and older compared to that of a placebo.
    Role: Principal Investigator

    1I01RX002961-01A1     (PADALA, KALPANA)Oct 1, 2020 - Sep 30, 2021
    Department of Veterans Affairs
    COVID Impact on Physical Activity in Older Veterans
    Role: Principal Investigator

         (PADALA, KALPANA)Jul 2, 2020 - Oct 30, 2021
    Romark Medical Research Institute
    A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Post-Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses in Elderly Residents of Long-Term Care Facilities (LTCF)
    Role: Co-Investigator

    I01RX002961     (PADALA, KALPANA P.)Apr 1, 2019 - Jan 31, 2024
    NIH
    Neuromodulation for Exercise Adherence in Older Veterans
    Role: Principal Investigator

    1I01RX002638-01A2     (Prasad Padala)Sep 1, 2018 - Dec 31, 2022
    VA ORD RR&D Merit
    Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment
    Role: Co-Investigator

    R01AG052510     (LYKETSOS, CONSTANTINE G)Sep 30, 2016 - May 31, 2023
    NIH
    Escitalopram for Agitation in Alzheimer Disease
    Role: Co-Investigator

    R01AG047992     (NEWHOUSE, PAUL A.)Sep 15, 2015 - May 31, 2021
    NIH
    Long-Term Nicotine Treatment of Mild Cognitive Impairment
    Role: Co-Investigator

         (PADALA, KALPANA)Oct 1, 2012 - Sep 30, 2015
    South Central VA Health Care Network Research Grants
    Wii-Fit for balance and gait in elderly Veterans
    Role: Principal Investigator

         (PADALA, KALPANA)Sep 30, 2009 - Sep 1, 2014
    Alzheimer's Association
    Wii-Fit for improving activity, gait and balance in Alzheimer’s Dementia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
    List All   |   Timeline
    1. Das A, Padala KP, Crawford CG, Teo A, Mendez DM, Phillips OA, Wright BC, House S, Padala PR. A systematic review of loneliness and social isolation scales used in epidemics and pandemics. Psychiatry Res. 2021 Oct 08; 306:114217. PMID: 34644661.
      View in: PubMed
    2. Padala PR, Rhodes RL, Brown LM, Padala KP. Celebrating the Greatest Generation during the pandemic. J Am Geriatr Soc. 2021 Nov; 69(11):3068-3070. PMID: 34528709.
      View in: PubMed
    3. Moo LR, Martinez E, Padala K, Dunay MA, Scali RR, Chen S, Thielke SM. Unexpected Findings During Double-blind Discontinuation of Acetylcholinesterase Inhibitor Medications. Clin Ther. 2021 06; 43(6):942-952. PMID: 34127273.
      View in: PubMed
    4. Padala KP, Padala PR, Leung YK, Dennis RA, Ho SM. Untangling the Complex Interactions of Open Burn Pit Exposure and Health Outcomes: Response to Brumage et al. Prim Care Companion CNS Disord. 2021 04 22; 23(2). PMID: 34000124.
      View in: PubMed
    5. Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Fennema H, Spiessens B, Offergeld K, Scheper G, Taylor KL, Robb ML, Treanor J, Barouch DH, Stoddard J, Ryser MF, Marovich MA, Neuzil KM, Corey L, Cauwenberghs N, Tanner T, Hardt K, Ruiz-Guiñazú J, Le Gars M, Schuitemaker H, Van Hoof J, Struyf F, Douoguih M. Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19. N Engl J Med. 2021 06 10; 384(23):2187-2201. PMID: 33882225.
      View in: PubMed
    6. Jennings SC, Manning KM, Bettger JP, Hall KM, Pearson M, Mateas C, Briggs BC, Oursler KK, Blanchard E, Lee CC, Castle S, Valencia WM, Katzel LI, Giffuni J, Kopp T, McDonald M, Harris R, Bean JF, Althuis K, Alexander NB, Padala KP, Abbate LM, Wellington T, Kostra J, Allsup K, Forman DE, Tayade AS, Wesley AD, Holder A, Morey MC. Rapid Transition to Telehealth Group Exercise and Functional Assessments in Response to COVID-19. Gerontol Geriatr Med. 2020 Jan-Dec; 6:2333721420980313. PMID: 33403222.
      View in: PubMed
    7. Padala KP, Padala PR, Leung YK, Dennis RA, Ho SM. Open Burn Pit Exposure and Concern About the COVID-19 Pandemic. Prim Care Companion CNS Disord. 2020 11 05; 22(6). PMID: 33166097.
      View in: PubMed
    8. Jiwani R, Wang CP, Orsak B, MacCarthy D, Kellogg D, Powers B, Wang J, Padala P, Padala K, Espinoza S. A geriatrics walking clinic improves hemoglobin A1c and timed gait in older veterans with type 2 diabetes. Geriatr Nurs. 2021 Mar-Apr; 42(2):566-569. PMID: 33158625.
      View in: PubMed
    9. Padala KP, Mendiratta P, Orr LC, Dean KT, Boozer EM, Lensing SY, Wei JY, Sullivan DH, Padala PR. An Interdisciplinary Approach to Educating Medical Students About Dementia Assessment and Treatment Planning. Fed Pract. 2020 Oct; 37(10):466-471. PMID: 33132685.
      View in: PubMed
    10. Padala KP, Wilson KB, Gauss CH, Stovall JD, Padala PR. VA Video Connect for Clinical Care in Older Adults in a Rural State During the COVID-19 Pandemic: Cross-Sectional Study. J Med Internet Res. 2020 09 30; 22(9):e21561. PMID: 32936773.
      View in: PubMed
    11. Padala PR, Padala KP, Majagi AS, Garner KK, Dennis RA, Sullivan DH. Selective serotonin reuptake inhibitors-associated apathy syndrome: A cross sectional study. Medicine (Baltimore). 2020 Aug 14; 99(33):e21497. PMID: 32871995.
      View in: PubMed
    12. Padala KP, Jendro AM, Wilson KB, Padala PR. Technology Use to Bridge the Gap of Social Distancing during COVID-19. J Geriatr Med Gerontol. 2020 Jun 29; 6(2). PMID: 33511321.
      View in: PubMed
    13. Lum HD, Padala KP, Dean KT, Padala PR. Psychogeriatric research during COVID-19 pandemic: qualitative analysis of participant views. Int Psychogeriatr. 2020 11; 32(11):1357-1360. PMID: 32522305.
      View in: PubMed
    14. Padala PR, Jendro AM, Gauss CH, Orr LC, Dean KT, Wilson KB, Parkes CM, Padala KP. Participant and Caregiver Perspectives on Clinical Research During Covid-19 Pandemic. J Am Geriatr Soc. 2020 Jun; 68(6):E14-E18. PMID: 32315076.
      View in: PubMed
    15. Padala PR, Jendro AM, Padala KP. Conducting Clinical Research During the COVID-19 Pandemic: Investigator and Participant Perspectives. JMIR Public Health Surveill. 2020 04 06; 6(2):e18887. PMID: 32250281.
      View in: PubMed
    16. Padala PR, Padala KP, Samant RS, James GA. Improvement of neuronal integrity with methylphenidate treatment for apathy in Alzheimer's disease. Int Psychogeriatr. 2020 04; 32(4):539-540. PMID: 32019622.
      View in: PubMed
    17. Padala KP, Parkes CM, Padala PR. Neuropsychological and Functional Impact of COVID-19 on Mild Cognitive Impairment. Am J Alzheimers Dis Other Demen. 2020 Jan-Dec; 35:1533317520960875. PMID: 32969235.
      View in: PubMed
    18. Padala PR, Boozer EM, Lensing SY, Parkes CM, Hunter CR, Dennis RA, Caceda R, Padala KP. Neuromodulation for Apathy in Alzheimer's Disease: A Double-Blind, Randomized, Sham-Controlled Pilot Study. J Alzheimers Dis. 2020; 77(4):1483-1493. PMID: 32925060.
      View in: PubMed
    19. Espinoza SE, Orsak B, Wang CP, MacCarthy D, Kellogg D, Powers B, Conde A, Moris M, Padala PR, Padala KP. An Individualized Low-Intensity Walking Clinic Leads to Improvement in Frailty Characteristics in Older Veterans. J Frailty Aging. 2019; 8(4):205-209. PMID: 31637407.
      View in: PubMed
    20. Padala KP, Hunter CR, Parkes CM, Lensing SY, Padala PR. Repetitive Transcranial Magnetic Stimulation Improves Executive Function and Music Rhythm. J Neuropsychiatry Clin Neurosci. 2019 Spring; 31(2):178-180. PMID: 30561282.
      View in: PubMed
    21. Padala PR, Dennis RA, Padala KP. Addressing Possible Effects of Sleep Apnea in a Study of Methylphenidate for Apathy in Alzheimer's Disease: Response to Kolla and Mansukhani. Am J Psychiatry. 2018 08 01; 175(8):792-793. PMID: 30064247.
      View in: PubMed
    22. Kakkera K, Padala KP, Kodali M, Padala PR. Association of chronic obstructive pulmonary disease with mild cognitive impairment and dementia. Curr Opin Pulm Med. 2018 03; 24(2):173-178. PMID: 29232279.
      View in: PubMed
    23. Scherer RW, Drye L, Mintzer J, Lanctôt K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH. The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Trials. 2018 Jan 18; 19(1):46. PMID: 29347996.
      View in: PubMed
    24. Padala PR, Padala KP, Lensing SY, Jackson AN, Hunter CR, Parkes CM, Dennis RA, Bopp MM, Caceda R, Mennemeier MS, Roberson PK, Sullivan DH. Repetitive transcranial magnetic stimulation for apathy in mild cognitive impairment: A double-blind, randomized, sham-controlled, cross-over pilot study. Psychiatry Res. 2018 03; 261:312-318. PMID: 29331848.
      View in: PubMed
    25. Dennis RA, Garner KK, Kortebein PM, Parkes CM, Bopp MM, Li S, Padala KP, Padala PR, Sullivan DH. Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. J Nutr Health Aging. 2018; 22(2):269-275. PMID: 29380855.
      View in: PubMed
    26. Padala PR, Padala KP, Lensing SY, Ramirez D, Monga V, Bopp MM, Roberson PK, Dennis RA, Petty F, Sullivan DH, Burke WJ. Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer's Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Psychiatry. 2018 02 01; 175(2):159-168. PMID: 28945120.
      View in: PubMed
    27. Padala KP, Padala PR, Lensing SY, Dennis RA, Bopp MM, Parkes CM, Garrison MK, Dubbert PM, Roberson PK, Sullivan DH. Efficacy of Wii-Fit on Static and Dynamic Balance in Community Dwelling Older Veterans: A Randomized Controlled Pilot Trial. J Aging Res. 2017; 2017:4653635. PMID: 28261500.
      View in: PubMed
    28. Padala KP, Padala PR, Lensing SY, Dennis RA, Bopp MM, Roberson PK, Sullivan DH. Home-Based Exercise Program Improves Balance and Fear of Falling in Community-Dwelling Older Adults with Mild Alzheimer's Disease: A Pilot Study. J Alzheimers Dis. 2017; 59(2):565-574. PMID: 28655135.
      View in: PubMed
    29. Padala KP, Padala PR, Taylor T, Montgomery B, Lensing SY, Bopp MM, Dubbert PM, Sullivan DH. Development and implementation of geriatric walking clinic: a home based individualized Veteran centric program. Fed Pract. 2016; 33(8):44-47.
    30. Padala KP, Padala PR, Taylor T, Montgomery B, Lensing SY, Bopp M, Dubbert PM, Sullivan DH. Development and Implementation of a Geriatric Walking Clinic. Fed Pract. 2016 Aug; 33(8):44-47. PMID: 30766199.
      View in: PubMed
    31. Dennis RA, Ponnappan U, Kodell RL, Garner KK, Parkes CM, Bopp MM, Padala KP, Peterson CA, Padala PR, Sullivan DH. Immune Function and Muscle Adaptations to Resistance exercise in Older Adults: Study Protocol for a Randomized Controlled Trial of a Nutritional Supplement. Trials. 2015 Mar 27; 16:121. PMID: 25872570.
      View in: PubMed
    32. Padala PR, Nabholz L, Padala KP, Ghormley C, Sullivan DH. Televideo clock drawing test to reach rural Veterans: feasibility in community-based outpatient clinics in the department of Veterans Affairs. J Am Geriatr Soc. 2015 Jan; 63(1):205-6. PMID: 25597588.
      View in: PubMed
    33. Sullivan DH, Johnson LE, Dennis RA, Roberson PK, Garner KK, Padala PR, Padala KP, Bopp MM. Nutrient intake, peripheral edema, and weight change in elderly recuperative care patients. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):712-8. PMID: 23183900.
      View in: PubMed
    34. Dennis RA, Johnson LE, Roberson PK, Heif M, Bopp MM, Garner KK, Padala KP, Padala PR, Dubbert PM, Sullivan DH. Changes in activities of daily living, nutrient intake, and systemic inflammation in elderly adults receiving recuperative care. J Am Geriatr Soc. 2012 Dec; 60(12):2246-53. PMID: 23176675.
      View in: PubMed
    35. Padala KP, Padala PR, McNeilly DP, Geske JA, Sullivan DH, Potter JF. The effect of HMG-CoA reductase inhibitors on cognition in patients with Alzheimer's dementia: a prospective withdrawal and rechallenge pilot study. Am J Geriatr Pharmacother. 2012 Oct; 10(5):296-302. PMID: 22921881.
      View in: PubMed
    36. Padala PR, Padala KP, Sullivan DH, Reynolds DW, Desouza CV, Potter JF, Burke WJ. Improvement of glycemic control using methylphenidate treatment of apathy: a preliminary report. J Am Geriatr Soc. 2012 Jul; 60(7):1383-4. PMID: 22788404.
      View in: PubMed
    37. Padala KP, Padala PR, Malloy TR, Geske JA, Dubbert PM, Dennis RA, Garner KK, Bopp MM, Burke WJ, Sullivan DH. Wii-fit for improving gait and balance in an assisted living facility: a pilot study. J Aging Res. 2012; 2012:597573. PMID: 22745909.
      View in: PubMed
    38. Padala PR, Padala KP, Monga V, Ramirez DA, Sullivan DH. Reversal of SSRI-associated apathy syndrome by discontinuation of therapy. Ann Pharmacother. 2012 Mar; 46(3):e8. PMID: 22353235.
      View in: PubMed
    39. Padala KP, Padala PR, Burke WJ. Wii-Fit as an adjunct for mild cognitive impairment: clinical perspectives. J Am Geriatr Soc. 2011 May; 59(5):932-3. PMID: 21568963.
      View in: PubMed
    40. Padala KP, Padala PR, Potter JF. Statins: a case for drug withdrawal in patients with dementia. J Am Geriatr Soc. 2010 Jun; 58(6):1214-6. PMID: 20722868.
      View in: PubMed
    41. Padala KP, Padala PR, Malloy T, Burke WJ. New onset multimodal hallucinations associated with mirtazapine: a case report. Int Psychogeriatr. 2010 Aug; 22(5):837-9. PMID: 20500925.
      View in: PubMed
    42. Padala KP, Padala PR, Wengel SP. Dose-dependent bradycardia with citalopram in an elderly patient. Prim Care Companion J Clin Psychiatry. 2010; 12(1):PCC.09100789. PMID: 20582300.
      View in: PubMed
    43. Padala KP, Potter JP, Tsuneya I. HMGCoA-reductase inhibitors in dementia: Benefit or harm. Clinical Medicine: Geriatrics. 2009; (3):13-22.
    44. Padala KP, Keller BK, Potter JF. Weight loss treatment in long-term care:are outcomes improved with oral supplements and appetite stimulants?. J Nutr Elder. 2007; 26(3-4):1-20. PMID: 18285290.
      View in: PubMed
    45. Padala PR, Rapuri SB, Padala KP. Alleviation of hot flashes with increase in venlafaxine dose. Prim Care Companion J Clin Psychiatry. 2007; 9(1):70-1. PMID: 17599176.
      View in: PubMed
    46. Padala PR, Sadiq HJ, Padala KP. Urinary obstruction with citalopram and aripiprazole combination in an elderly patient. J Clin Psychopharmacol. 2006 Dec; 26(6):667-8. PMID: 17110829.
      View in: PubMed
    47. Padala KP, Padala PR, Potter JF. Simvastatin-induced decline in cognition. Ann Pharmacother. 2006 Oct; 40(10):1880-3. PMID: 16940411.
      View in: PubMed
    48. Padala KP, Hinners CK, Padala PR. Mirtazapine therapy for dysgeusia in an elderly patient. Prim Care Companion J Clin Psychiatry. 2006; 8(3):178-80. PMID: 16912823.
      View in: PubMed
    Padala's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description