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Arny Ferrando

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentGeriatrics, College of Medicine
DivisionGeriatrics Faculty
Address2129 Institute on Aging
629 Jack Stephens Drive
Mail Slot # 806
Little Rock AR 72205
Phone501-526-5711
ORCID ORCID Icon0000-0003-2916-7878 Additional info
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    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Director, CTRAL


    Collapse Research 
    Collapse research activities and funding
    W81XWH1C0067     (FERRANDO, ARNY)Mar 29, 2021 - Mar 31, 2025
    U.S. Army Research Institute of Environmental Medicine
    Protein Kinetic Response to Calorie Deprivation:
    Role: Principal Investigator
    W81XWH21C0067     (FERRANDO, ARNY)Mar 29, 2021 - Mar 31, 2025
    U.S. Army Research Institute of Environmental Medicine
    Protein Kinetic Response to Calorie Deprivation:
    Role: Principal Investigator
    W81XWH19C0162     (FERRANDO, ARNY)Jul 11, 2019 - Jul 10, 2021
    U.S. Army Research Institute of Environmental Medicine - Pass Through: Pennington Biomedical Research Center
    Ferrando - Optimizing Performance for Soldiers II (OPS II ) Pennington/USARIEM
    Role: Principal Investigator
    W81XWH19P0074     (FERRANDO, ARNY)Mar 1, 2019 - Feb 29, 2020
    US Department of the Army
    Ferrando - Altitude wUSARIEM - The mechanistic effects of acute hypobaric hypoxia on exogenous cargohydrate utilization during steady-state aerobic exercise
    Role: Principal Investigator
    W81XWH1820021     (FERRANDO, ARNY)Jul 1, 2018 - Jun 30, 2023
    U.S. Army Research Institute of Environmental Medicine
    Ferrando - Warfighter Recovery Nutrition: Optimizing Protein Quantity, Quality, and Combat Ration Delivery Systems
    Role: Principal Investigator
    18-CVM     (FERRANDO, ARNY)Jan 1, 2018 - Sep 30, 2018
    Auburn University
    Ferrando - AURIC Year 2
    Role: Principal Investigator
    18-CVM-101069-UAMS     (FERRANDO, ARNY)Jan 1, 2018 - Sep 30, 2018
    Auburn University
    Ferrando - AURIC Year 2
    Role: Principal Investigator
    PO US001-0000536510     (FERRANDO, ARNY)Apr 1, 2016 - Sep 30, 2017
    U.S. Army Research Institute of Environmental Medicine - Pass Through: Battelle Memorial Institute
    Ferrando - Pikes Peak
    Role: Principal Investigator
    R01HD084124     (FERRANDO, ARNY)Apr 15, 2015 - Feb 28, 2020
    NIH/National Institutes of Health - Pass Through: University of Alabama at Birmingham
    Overcoming TWEAK Signaling to Restore Muscle and Mobility Function after Joint Replacement - Continuation - Continuation
    Role: Principal Investigator
    R01HD084124     (FERRANDO, ARNY)Apr 15, 2015 - Feb 28, 2020
    NIH/National Institutes of Health - Pass Through: University of Alabama at Birmingham
    Overcoming TWEAK Signaling to Restore Muscle and Mobility Function after Joint Replacement
    Role: Principal Investigator
    BYM338E2202-     (FERRANDO, ARNY)Oct 8, 2014 - Dec 31, 2016
    NOVARTIS Pharmaceuticals Corporation
    FE CTA 6-8-2015
    Role: Principal Investigator
    1211     (FERRANDO, ARNY)Jun 1, 2013 - May 31, 2015
    National Dairy Council
    Ferrando - D.E.B. Dairy - Effect of Dietary Protein Intake Distribution on Protein Metabolism and Skeletal Muscle
    Role: Principal Investigator
    1165     (FERRANDO, ARNY)Oct 1, 2012 - Dec 31, 2014
    The Dairy Research Institute
    Ferrando - Dairy Macronutrient Effects on the Metabolic System
    Role: Principal Investigator
    P30AG028718     (WEI, JEANNE Y)Sep 1, 2011 - Aug 31, 2018
    NIH
    Arkansas Claude Pepper Older Americans Independence Center at UAMS
    Role: Co-Investigator
    1050     (FERRANDO, ARNY)Jun 1, 2011 - Dec 31, 2012
    National Dairy Council
    Ferrando: Effect of Dietary Protein Intake Pattern on Skeletal Muscle in Older Individuals
    Role: Principal Investigator
    RC2GM092277     (WOLFE, ROBERT R)Sep 30, 2009 - Aug 31, 2011
    NIH
    Stable Isotope Analytical Core for Studies in Human Metabolism
    Role: Co-Investigator
    PS-IPC     (FERRANDO, ARNY)Apr 1, 2009 - Aug 31, 2010
    Medical Nutrition USA, Inc.
    Effects of Pro-Stat Immuno-Protein Complex (PS-IPC)Supplementation on Muscle Mass and Function, Inflammatory Markers, and Immune Function in Older Adu
    Role: Principal Investigator
    R01AR052293     (FERRANDO, ARNY A)Sep 1, 2006 - Aug 31, 2011
    NIH
    Restoration of Muscle Following Hip Surgery
    Role: Principal Investigator
    NPFR00403     (WOLFE, ROBERT R)Aug 1, 2006 - Jul 31, 2009
    National Space Biomedical Research Institute - Pass Through: Baylor College of Medicine
    Nutritional Countermeasures to Ameliorate Losses in Muscle Mass and Function
    Role: Principal Investigator
    P50GM060338     (FERRANDO, ARNY)Jul 1, 2006 - Jun 30, 2010
    NIH/Nat. Inst. of General Medical Sciences - Pass Through: University of Texas Medical Branch
    Glucocorticoid antagonism in burned children / Project 2
    Role: Principal Investigator
    R01GM057295     (FERRANDO, ARNY A)May 1, 1998 - Jun 30, 2005
    NIH
    Testosterone Effects on Muscle in Burn Injury
    Role: Principal Investigator
    R01DK034817     (WOLFE, ROBERT R)Dec 1, 1984 - Sep 30, 2014
    NIH
    Substrate Cycling in Energy Metabolism
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Margolis LM, Allen JT, Murphy NE, Carrigan CT, Howard EE, Barney DE, Drummer DJ, Michalak J, Ferrando AA, Pasiakos SM, Gwin JA. Carbohydrate supplementation maintains physical performance during short-term energy deficit despite reductions in exogenous glucose oxidation. Am J Physiol Endocrinol Metab. 2025 Feb 01; 328(2):E242-E253. PMID: 39814548.
      View in: PubMed
    2. Church DD, Hirsch KR, Kviatkovsky SA, Matthews JJ, Henderson RA, Azhar G, Wolfe RR, Ferrando AA. Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial. J Nutr. 2024 Dec 28. PMID: 39736329.
      View in: PubMed
    3. Wolfe RR, Church DD, Ferrando AA, Moughan PJ. Consideration of the role of protein quality in determining dietary protein recommendations. Front Nutr. 2024; 11:1389664. PMID: 39606577.
      View in: PubMed
    4. Church DD, Hirsch KR, Kviatkovsky SA, Matthews JJ, Ferrando AA, Azhar G, Wolfe RR. The anabolic response to a ground beef patty and soy-based meat alternative: a randomized controlled trial. Am J Clin Nutr. 2024 Nov; 120(5):1085-1092. PMID: 39222687.
      View in: PubMed
    5. Gwin JA, Church DD, Allen JT, Wilson MA, Carrigan CT, Murphy NE, Varanoske AN, Margolis LM, Wolfe RR, Ferrando AA, Pasiakos SM. Consuming Whey Protein with Added Essential Amino Acids, Not Carbohydrate, Maintains Postexercise Anabolism While Underfed. Med Sci Sports Exerc. 2025 Jan 01; 57(1):70-80. PMID: 39160756.
      View in: PubMed
    6. Michel JM, Hettinger Z, Ambrosio F, Egan B, Roberts MD, Ferrando AA, Graham ZA, Bamman MM. Mitigating skeletal muscle wasting in unloading and augmenting subsequent recovery. J Physiol. 2024 Jul 19. PMID: 39031694.
      View in: PubMed
    7. Antonio J, Evans C, Ferrando AA, Stout JR, Antonio B, Cinteo H, Harty P, Arent SM, Candow DG, Forbes SC, Kerksick CM, Pereira F, Gonzalez D, Kreider RB. Common questions and misconceptions about protein supplementation: what does the scientific evidence really show? J Int Soc Sports Nutr. 2024 Dec; 21(1):2341903. PMID: 38626029.
      View in: PubMed
    8. Church DD, Ferrando AA, Wolfe RR. Stimulation of muscle protein synthesis with low-dose amino acid composition in older individuals. Front Nutr. 2024; 11:1360312. PMID: 38524852.
      View in: PubMed
    9. Church DD, Zamir A, Escalante G, Ben-Zeev T, Levi C, Ferrando AA, Hoffman JR. Early Life Androgen Administration Attenuates Aging Related Declines in Muscle Protein Synthesis. Med Sci Sports Exerc. 2024 Jun 01; 56(6):1118-1123. PMID: 38376993.
      View in: PubMed
    10. Ferrando AA, Wolfe RR, Hirsch KR, Church DD, Kviatkovsky SA, Roberts MD, Stout JR, Gonzalez DE, Sowinski RJ, Kreider RB, Kerksick CM, Burd NA, Pasiakos SM, Ormsbee MJ, Arent SM, Arciero PJ, Campbell BI, VanDusseldorp TA, Jager R, Willoughby DS, Kalman DS, Antonio J. International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance. J Int Soc Sports Nutr. 2023 Dec; 20(1):2263409. PMID: 37800468.
      View in: PubMed
    11. Varanoske AN, Harris MN, Hebert C, Johannsen NM, Heymsfield SB, Greenway FL, Ferrando AA, Rood JC, Pasiakos SM. Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi-stressor military operations. Physiol Rep. 2023 03; 11(6):e15649. PMID: 36949577.
      View in: PubMed
    12. Smith-Ryan AE, Hirsch KR, Cabre HE, Gould LM, Gordon AN, Ferrando AA. Menopause Transition: A Cross-Sectional Evaluation on Muscle Size and Quality. Med Sci Sports Exerc. 2023 07 01; 55(7):1258-1264. PMID: 36878186.
      View in: PubMed
    13. Drummer DJ, Lavin KM, Graham ZA, O'Bryan SM, McAdam JS, Lixandr?o ME, Seay R, Aban I, Siegel HJ, Ghanem E, Singh JA, Bonfitto A, Antone J, Reiman R, Hutchins E, Van Keuren-Jensen K, Schutzler SE, Barnes CL, Ferrando AA, Bridges SL, Bamman MM. Muscle transcriptomic circuits linked to periarticular physiology in end-stage osteoarthritis. Physiol Genomics. 2022 12 01; 54(12):501-513. PMID: 36278270.
      View in: PubMed
    14. Wolfe RR, Kim IY, Park S, Ferrando A. Tracing metabolic flux to assess optimal dietary protein and amino acid consumption. Exp Mol Med. 2022 09; 54(9):1323-1331. PMID: 36075948.
      View in: PubMed
    15. Berryman CE, McClung HL, Sepowitz JJ, Gaffney-Stomberg E, Ferrando AA, McClung JP, Pasiakos SM. Testosterone status following short-term, severe energy deficit is associated with fat-free mass loss in U.S. Marines. Physiol Rep. 2022 09; 10(18):e15461. PMID: 36117330.
      View in: PubMed
    16. Varanoske AN, Harris MN, Hebert C, Howard EE, Johannsen NM, Heymsfield SB, Greenway FL, Margolis LM, Lieberman HR, Beyl RA, Church DD, Ferrando AA, Pasiakos SM, Rood JC. Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations. J Appl Physiol (1985). 2022 08 01; 133(2):426-442. PMID: 35796614.
      View in: PubMed
    17. Gonzalez DE, McAllister MJ, Waldman HS, Ferrando AA, Joyce J, Barringer ND, Dawes JJ, Kieffer AJ, Harvey T, Kerksick CM, Stout JR, Ziegenfuss TN, Zapp A, Tartar JL, Heileson JL, VanDusseldorp TA, Kalman DS, Campbell BI, Antonio J, Kreider RB. International society of sports nutrition position stand: tactical athlete nutrition. J Int Soc Sports Nutr. 2022; 19(1):267-315. PMID: 35813846.
      View in: PubMed
    18. Hirsch KR, Church DD, Wolfe RR, Ferrando AA. Continuous oral stable isotope ingestion to measure whole-body protein turnover. Clin Nutr ESPEN. 2022 06; 49:385-389. PMID: 35623841.
      View in: PubMed
    19. Drummer DJ, McAdam JS, Seay R, Aban I, Lavin KM, Wiggins D, Touliatos G, Yang S, Kelley C, Tuggle SC, Peoples B, Siegel H, Ghanem E, Singh JA, Schutzler S, Barnes CL, Ferrando AA, Bridges SL, Bamman MM. Perioperative assessment of muscle inflammation susceptibility in patients with end-stage osteoarthritis. J Appl Physiol (1985). 2022 04 01; 132(4):984-994. PMID: 35238652.
      View in: PubMed
    20. Witard OC, Ferrando AA, Phillips SM. Celebrating the Professional Life of Professor Kevin D. Tipton (1961-2022). Int J Sport Nutr Exerc Metab. 2022 05 01; 32(3):129-132. PMID: 35219275.
      View in: PubMed
    21. Banks NF, Rogers EM, Church DD, Ferrando AA, Jenkins NDM. The contributory role of vascular health in age-related anabolic resistance. J Cachexia Sarcopenia Muscle. 2022 02; 13(1):114-127. PMID: 34951146.
      View in: PubMed
    22. Coker MS, Schutzler SE, Park S, Williams RH, Ferrando AA, Deutz NEP, Wolfe RR, Coker RH. Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef. Int J Circumpolar Health. 2021 12; 80(1):1897222. PMID: 33704030.
      View in: PubMed
    23. Osburn SC, Vann CG, Church DD, Ferrando AA, Roberts MD. Proteasome- and Calpain-Mediated Proteolysis, but Not Autophagy, Is Required for Leucine-Induced Protein Synthesis in C2C12 Myotubes. Physiologia. 2021 Dec; 1(1):22-33. PMID: 34927140.
      View in: PubMed
    24. Ruple BA, Godwin JS, Mesquita PHC, Osburn SC, Sexton CL, Smith MA, Ogletree JC, Goodlett MD, Edison JL, Ferrando AA, Fruge AD, Kavazis AN, Young KC, Roberts MD. Myofibril and Mitochondrial Area Changes in Type I and II Fibers Following 10 Weeks of Resistance Training in Previously Untrained Men. Front Physiol. 2021; 12:728683. PMID: 34630147.
      View in: PubMed
    25. Church DD, Schutzler SE, Wolfe RR, Ferrando AA. Perioperative amino acid infusion reestablishes muscle net balance during total hip arthroplasty. Physiol Rep. 2021 09; 9(18):e15055. PMID: 34558214.
      View in: PubMed
    26. Hirsch KR, Greenwalt CE, Cabre HE, Gould LM, Brewer GJ, Blue MNM, Ferrando AA, Huffman KM, Mayer-Davis EJ, Ryan ED, Smith-Ryan AE. Metabolic effects of high-intensity interval training and essential amino acids. Eur J Appl Physiol. 2021 Dec; 121(12):3297-3311. PMID: 34427732.
      View in: PubMed
    27. Drummer D, McAdam J, Seay R, Ferrando A, Bridges SL, Singh JA, Bamman M. Osteoarthritis Progression: Mitigation and Rehabilitation Strategies. Front Rehabil Sci. 2021; 2:724052. PMID: 36188773.
      View in: PubMed
    28. Varanoske AN, Harris MN, Hebert C, Howard EE, Johannsen NM, Heymsfield SB, Greenway FL, Margolis LM, Lieberman HR, Church DD, Ferrando AA, Rood JC, Pasiakos SM. Effects of testosterone undecanoate on performance during multi-stressor military operations: A trial protocol for the Optimizing Performance for Soldiers II study. Contemp Clin Trials Commun. 2021 Sep; 23:100819. PMID: 34278044.
      View in: PubMed
    29. Azhar G, Wei JY, Schutzler SE, Coker K, Gibson RV, Kirby MF, Ferrando AA, Wolfe RR. Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):1184-1191. PMID: 33475727.
      View in: PubMed
    30. Hirsch KR, Wolfe RR, Ferrando AA. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021 May 15; 13(5). PMID: 34063333.
      View in: PubMed
    31. Park S, Church DD, Schutzler SE, Azhar G, Kim IY, Ferrando AA, Wolfe RR. Metabolic Evaluation of the Dietary Guidelines' Ounce Equivalents of Protein Food Sources in Young Adults: A Randomized Controlled Trial. J Nutr. 2021 05 11; 151(5):1190-1196. PMID: 33693735.
      View in: PubMed
    32. Margolis LM, Karl JP, Wilson MA, Coleman JL, Ferrando AA, Young AJ, Pasiakos SM. Metabolomic profiles are reflective of hypoxia-induced insulin resistance during exercise in healthy young adult males. Am J Physiol Regul Integr Comp Physiol. 2021 07 01; 321(1):R1-R11. PMID: 33949213.
      View in: PubMed
    33. Park S, Church DD, Starck C, Schutzler SE, Azhar G, Kim IY, Ferrando AA, Moughan PJ, Wolfe RR. Correction to: The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. Eur J Nutr. 2021 Mar; 60(2):1149-1151. PMID: 33306152.
      View in: PubMed
    34. Roberson PA, Mobley CB, Romero MA, Haun CT, Osburn SC, Mumford PW, Vann CG, Greer RA, Ferrando AA, Roberts MD. LAT1 Protein Content Increases Following 12 Weeks of Resistance Exercise Training in Human Skeletal Muscle. Front Nutr. 2020; 7:628405. PMID: 33521042.
      View in: PubMed
    35. Gwin JA, Church DD, Hatch-McChesney A, Allen JT, Wilson MA, Varanoske AN, Carrigan CT, Murphy NE, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study. J Int Soc Sports Nutr. 2021 Jan 07; 18(1):4. PMID: 33413462.
      View in: PubMed
    36. Hirsch KR, Greenwalt CE, Saylor HE, Gould LM, Harrison CH, Brewer GJ, Blue MNM, Ferrando AA, Huffman KM, Mayer-Davis EJ, Ryan ED, Smith-Ryan AE. High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover. Physiol Rep. 2021 01; 9(1):e14655. PMID: 33369879.
      View in: PubMed
    37. Duarte-Rojo A, Bloomer PM, Rogers RJ, Hassan MA, Dunn MA, Tevar AD, Vivis SL, Bataller R, Hughes CB, Ferrando AA, Jakicic JM, Kim WR. Introducing EL-FIT (Exercise and Liver FITness): A Smartphone App to Prehabilitate and Monitor Liver Transplant Candidates. Liver Transpl. 2021 04; 27(4):502-512. PMID: 33232547.
      View in: PubMed
    38. Church DD, Hirsch KR, Park S, Kim IY, Gwin JA, Pasiakos SM, Wolfe RR, Ferrando AA. Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding. Nutrients. 2020 Dec 02; 12(12). PMID: 33276485.
      View in: PubMed
    39. Hirsch KR, Church DD, Kim IY, Park S, Wolfe RR, Ferrando AA. Comparison of basal whole-body protein kinetics and muscle protein synthesis between young and older adults. Physiol Rep. 2020 12; 8(23):e14633. PMID: 33278070.
      View in: PubMed
    40. Park S, Jang J, Choi MD, Shin YA, Schutzler S, Azhar G, Ferrando AA, Wolfe RR, Kim IY. The Anabolic Response to Dietary Protein Is Not Limited by the Maximal Stimulation of Protein Synthesis in Healthy Older Adults: A Randomized Crossover Trial. Nutrients. 2020 Oct 26; 12(11). PMID: 33114585.
      View in: PubMed
    41. Wu H, Jang J, Dridi S, Ferrando AA, Wolfe RR, Kim IY, Baum JI. Net protein balance correlates with expression of autophagy, mitochondrial biogenesis, and fat metabolism-related genes in skeletal muscle from older adults. Physiol Rep. 2020 10; 8(19):e14575. PMID: 33063954.
      View in: PubMed
    42. Park S, Church DD, Starck C, Schutzler SE, Azhar G, Kim IY, Ferrando AA, Moughan PJ, Wolfe RR. The impact of Hayward green kiwifruit on dietary protein digestion and protein metabolism. Eur J Nutr. 2021 Mar; 60(2):1141-1148. PMID: 32970234.
      View in: PubMed
    43. Gwin JA, Church DD, Wolfe RR, Ferrando AA, Pasiakos SM. Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit. Nutrients. 2020 Aug 15; 12(8). PMID: 32824200.
      View in: PubMed
    44. Wardle SL, Macnaughton LS, McGlory C, Witard OC, Dick JR, Whitfield PD, Ferrando AA, Wolfe RR, Kim IY, Hamilton DL, Moran CN, Tipton KD, Galloway SDR. Human skeletal muscle metabolic responses to 6 days of high-fat overfeeding are associated with dietary n-3PUFA content and muscle oxidative capacity. Physiol Rep. 2020 08; 8(16):e14529. PMID: 32845565.
      View in: PubMed
    45. Lin FP, Ferrando AA, Dennis RA, Dunn MA, Kim WR, Duarte-Rojo A. Exercise-Induced Hyperammonemia Does Not Precipitate Overt Hepatic Encephalopathy. Hepatology. 2020 08; 72(2):778-780. PMID: 31997375.
      View in: PubMed
    46. Gwin JA, Church DD, Hatch-McChesney A, Howard EE, Carrigan CT, Murphy NE, Wilson MA, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study. Clin Nutr. 2021 03; 40(3):767-777. PMID: 32768315.
      View in: PubMed
    47. Chen HW, Ferrando AA, Dunn MA, Kim WR, Duarte-Rojo A. Cadence From Physical Activity Trackers for Monitoring of Home-Based Exercise Intensity in Advanced Liver Disease. Liver Transpl. 2020 05; 26(5):718-721. PMID: 32145132.
      View in: PubMed
    48. Park S, Church DD, Azhar G, Schutzler SE, Ferrando AA, Wolfe RR. Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults. J Int Soc Sports Nutr. 2020 Feb 10; 17(1):9. PMID: 32041644.
      View in: PubMed
    49. Chen HW, Ferrando A, White MG, Dennis RA, Xie J, Pauly M, Park S, Bartter T, Dunn MA, Ruiz-Margain A, Kim WR, Duarte-Rojo A. Home-Based Physical Activity and Diet Intervention to Improve Physical Function in Advanced Liver Disease: A Randomized Pilot Trial. Dig Dis Sci. 2020 11; 65(11):3350-3359. PMID: 31907774.
      View in: PubMed
    50. Margolis LM, Wilson MA, Whitney CC, Carrigan CT, Murphy NE, Radcliffe PN, Gwin JA, Church DD, Wolfe RR, Ferrando AA, Young AJ, Pasiakos SM. Acute hypoxia reduces exogenous glucose oxidation, glucose turnover, and metabolic clearance rate during steady-state aerobic exercise. Metabolism. 2020 02; 103:154030. PMID: 31778707.
      View in: PubMed
    51. Wolfe RR, Park S, Kim IY, Moughan PJ, Ferrando AA. Advances in stable isotope tracer methodology part 2: new thoughts about an "old" method-measurement of whole body protein synthesis and breakdown in the fed state. J Investig Med. 2020 01; 68(1):11-15. PMID: 31554677.
      View in: PubMed
    52. Wolfe RR, Park S, Kim IY, Starck C, Marquis BJ, Ferrando AA, Moughan PJ. Reply to Letter to the Editor: "The intrinsically labeled protein approach is the preferred method to quantify the release of dietary protein-derived amino acids into the circulation". Am J Physiol Endocrinol Metab. 2019 09 01; 317(3):E435. PMID: 31423801.
      View in: PubMed
    53. Church DD, Pasiakos SM, Wolfe RR, Ferrando AA. Acute testosterone administration does not affect muscle anabolism. Nutr Metab (Lond). 2019; 16:56. PMID: 31440303.
      View in: PubMed
    54. Church DD, Gwin JA, Wolfe RR, Pasiakos SM, Ferrando AA. Mitigation of Muscle Loss in Stressed Physiology: Military Relevance. Nutrients. 2019 Jul 24; 11(8). PMID: 31344809.
      View in: PubMed
    55. Kim IY, Park S, Smeets ETHC, Schutzler S, Azhar G, Wei JY, Ferrando AA, Wolfe RR. Consumption of a Specially-Formulated Mixture of Essential Amino Acids Promotes Gain in Whole-Body Protein to a Greater Extent than a Complete Meal Replacement in Older Women with Heart Failure. Nutrients. 2019 Jun 17; 11(6). PMID: 31212940.
      View in: PubMed
    56. Parry HA, Mobley CB, Mumford PW, Romero MA, Haun CT, Zhang Y, Roberson PA, Zempleni J, Ferrando AA, Vechetti IJ, McCarthy JJ, Young KC, Roberts MD, Kavazis AN. Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Front Physiol. 2019; 10:436. PMID: 31040795.
      View in: PubMed
    57. Wolfe RR, Park S, Kim IY, Starck C, Marquis BJ, Ferrando AA, Moughan PJ. Quantifying the contribution of dietary protein to whole body protein kinetics: examination of the intrinsically labeled proteins method. Am J Physiol Endocrinol Metab. 2019 07 01; 317(1):E74-E84. PMID: 30939051.
      View in: PubMed
    58. Pasiakos SM, Berryman CE, Carbone JW, Murphy NE, Carrigan CT, Bamman MM, Ferrando AA, Young AJ, Margolis LM. Muscle Fn14 gene expression is associated with fat-free mass retention during energy deficit at high altitude. Physiol Rep. 2018 07; 6(14):e13801. PMID: 30009538.
      View in: PubMed
    59. Margolis LM, Carbone JW, Berryman CE, Carrigan CT, Murphy NE, Ferrando AA, Young AJ, Pasiakos SM. Severe energy deficit at high altitude inhibits skeletal muscle mTORC1-mediated anabolic signaling without increased ubiquitin proteasome activity. FASEB J. 2018 Jun 07; fj201800163RR. PMID: 29878853.
      View in: PubMed
    60. Berryman CE, Young AJ, Karl JP, Kenefick RW, Margolis LM, Cole RE, Carbone JW, Lieberman HR, Kim IY, Ferrando AA, Pasiakos SM. Severe negative energy balance during 21 d at high altitude decreases fat-free mass regardless of dietary protein intake: a randomized controlled trial. FASEB J. 2018 02; 32(2):894-905. PMID: 29066613.
      View in: PubMed
    61. Duarte-Rojo A, Ruiz-Marg?in A, Monta?o-Loza AJ, Mac?as-Rodr?guez RU, Ferrando A, Kim WR. Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list. Liver Transpl. 2018 01; 24(1):122-139. PMID: 29024353.
      View in: PubMed
    62. Kim IY, Shin YA, Schutzler SE, Azhar G, Wolfe RR, Ferrando AA. Quality of meal protein determines anabolic response in older adults. Clin Nutr. 2018 12; 37(6 Pt A):2076-2083. PMID: 29066101.
      View in: PubMed
    63. J?ger R, Kerksick CM, Campbell BI, Cribb PJ, Wells SD, Skwiat TM, Purpura M, Ziegenfuss TN, Ferrando AA, Arent SM, Smith-Ryan AE, Stout JR, Arciero PJ, Ormsbee MJ, Taylor LW, Wilborn CD, Kalman DS, Kreider RB, Willoughby DS, Hoffman JR, Krzykowski JL, Antonio J. International Society of Sports Nutrition Position Stand: protein and exercise. J Int Soc Sports Nutr. 2017; 14:20. PMID: 28642676.
      View in: PubMed
    64. Kim IY, Schutzler SE, Azhar G, Wolfe RR, Ferrando AA, Coker RH. Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial. BMC Nutr. 2017; 3. PMID: 28713581.
      View in: PubMed
    65. Kim IY, Schutzler S, Schrader AM, Spencer HJ, Azhar G, Wolfe RR, Ferrando AA. Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial. Clin Nutr. 2018 04; 37(2):488-493. PMID: 28318687.
      View in: PubMed
    66. Angle C, Waggoner LP, Ferrando A, Haney P, Passler T. Canine Detection of the Volatilome: A Review of Implications for Pathogen and Disease Detection. Front Vet Sci. 2016; 3:47. PMID: 27446935.
      View in: PubMed
    67. Kim IY, Schutzler S, Schrader A, Spencer HJ, Azhar G, Ferrando AA, Wolfe RR. The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults. Am J Physiol Endocrinol Metab. 2016 Jan 01; 310(1):E73-80. PMID: 26530155.
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    68. Bamman MM, Ferrando AA, Evans RP, Stec MJ, Kelly NA, Gruenwald JM, Corrick KL, Trump JR, Singh JA. Muscle inflammation susceptibility: a prognostic index of recovery potential after hip arthroplasty? Am J Physiol Endocrinol Metab. 2015 Apr 15; 308(8):E670-9. PMID: 25670829.
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    69. Kim IY, Schutzler S, Schrader A, Spencer H, Kortebein P, Deutz NE, Wolfe RR, Ferrando AA. Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults. Am J Physiol Endocrinol Metab. 2015 Jan 01; 308(1):E21-8. PMID: 25352437.
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    70. Kedia AW, Hofheins JE, Habowski SM, Ferrando AA, Gothard MD, Lopez HL. Effects of a pre-workout supplement on lean mass, muscular performance, subjective workout experience and biomarkers of safety. Int J Med Sci. 2014; 11(2):116-26. PMID: 24465156.
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    71. Witard OC, Cocke TL, Ferrando AA, Wolfe RR, Tipton KD. Increased net muscle protein balance in response to simultaneous and separate ingestion of carbohydrate and essential amino acids following resistance exercise. Appl Physiol Nutr Metab. 2014 Mar; 39(3):329-39. PMID: 24552374.
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    72. Ferrando AA. Increased protein intake in military special operations. J Nutr. 2013 Nov; 143(11):1852S-1856S. PMID: 24027188.
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    73. Lopez HL, Ziegenfuss TN, Hofheins JE, Habowski SM, Arent SM, Weir JP, Ferrando AA. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. J Int Soc Sports Nutr. 2013 Apr 19; 10(1):22. PMID: 23601452.
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    74. Jeschke MG, Williams FN, Finnerty CC, Rodriguez NA, Kulp GA, Ferrando A, Norbury WB, Suman OE, Kraft R, Branski LK, Al-mousawi AM, Herndon DN. The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes. PLoS One. 2012; 7(5):e35465. PMID: 22606232.
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    75. Deutz NE, Safar A, Schutzler S, Memelink R, Ferrando A, Spencer H, van Helvoort A, Wolfe RR. Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food. Clin Nutr. 2011 Dec; 30(6):759-68. PMID: 21683485.
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    76. Tuvdendorj D, Chinkes DL, Zhang XJ, Ferrando AA, Elijah IE, Mlcak RP, Finnerty CC, Wolfe RR, Herndon DN. Adult patients are more catabolic than children during acute phase after burn injury: a retrospective analysis on muscle protein kinetics. Intensive Care Med. 2011 Aug; 37(8):1317-22. PMID: 21647721.
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    77. Tuvdendorj D, Chinkes DL, Zhang XJ, Suman OE, Aarsland A, Ferrando A, Kulp GA, Jeschke MG, Wolfe RR, Herndon DN. Long-term oxandrolone treatment increases muscle protein net deposition via improving amino acid utilization in pediatric patients 6 months after burn injury. Surgery. 2011 May; 149(5):645-53. PMID: 21333314.
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    78. Boivin MA, Battah SI, Dominic EA, Kalantar-Zadeh K, Ferrando A, Tzamaloukas AH, Dwivedi R, Ma TA, Moseley P, Raj DS. Activation of caspase-3 in the skeletal muscle during haemodialysis. Eur J Clin Invest. 2010 Oct; 40(10):903-10. PMID: 20636378.
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    79. Pasiakos SM, Vislocky LM, Carbone JW, Altieri N, Konopelski K, Freake HC, Anderson JM, Ferrando AA, Wolfe RR, Rodriguez NR. Acute energy deprivation affects skeletal muscle protein synthesis and associated intracellular signaling proteins in physically active adults. J Nutr. 2010 Apr; 140(4):745-51. PMID: 20164371.
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    81. Ferrando AA, Paddon-Jones D, Hay NP, Kortebein P, Ronsen O, Williams R, McComb A, Symons B, Wolfe RR, Evans WJ. Essential amino acid supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clinical Nutrition. 2010; 29:18-23.
    82. Cree M.G., Paddon-Jones D., Newcomer B.R., Aarsland A., Wolfe R.R., Ferrando A.A. 28 day bed-rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. 2010; 59:703-710.
    83. Cree MG, Paddon-Jones D, Newcomer BR, Ronsen O, Aarsland A, Wolfe RR, Ferrando A. Twenty-eight-day bed rest with hypercortisolemia induces peripheral insulin resistance and increases intramuscular triglycerides. Metabolism. 2010 May; 59(5):703-10. PMID: 19919871.
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    84. Mayhew DL, Kim JS, Cross JM, Ferrando AA, Bamman MM. Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans. J Appl Physiol (1985). 2009 Nov; 107(5):1655-62. PMID: 19589955.
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    85. Campbell, W.W., Haub M.D., Wolfe, R.R., Ferrando AA, Sullivan, D.H., Apolzan, J.W., Iglay, H.B. Resistance training preserves fat-free mass without changes in protein metabolism after weight loss in older women. Obesity. 2009; 17(7):1332-9.
    86. Symons, T.B., Sheffield-Moore, M., Chinkles, D.L., Ferrando AA, Paddon-Jones, D. Artificial gravity maintains skeletal muscle protein synthesis during 21 days simulated microgravity. J Appl Physiol. 2009; 107(1):34-8.
    87. Ferrando AA, Paddon-Jones D, Hays NP, Kortebein P, Ronsen O, Williams RH, McComb A, Symons TB, Wolfe RR, Evans W. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2010 Feb; 29(1):18-23. PMID: 19419806.
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    88. Real PJ, Ferrando AA. NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia. Leukemia. 2009; Epub ahead of print.
    89. Gonzalez-Garcia S, Garcia-Peydro M, Martin-Gayo E, Ballestar E, Esteller M, Bornstein R, De la Pompa JL, Ferrando AA, Toribio ML. CSL-MAMl-dependent Notch1 signaling controls T lineage-specific IL-7R {alpha} gene expression in early human thymopoiesis and leukemia. J Exp Med. 2009; 206(4):779-91.
    90. Tipton KD, Elliott TA, Ferrando AA, Aarsland AA, Wolfe RR. Stimulation of muscle anabolism by resistance exercise and ingestion of leucine plus protein. Appl Physiol Nutr Metab. 2009 Apr; 34(2):151-61. PMID: 19370045.
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    91. Borsheim, E., Bui, Q-U. T, Tisser, S, Cree, M.G., Ronen, O., Morio, B., Ferrando AA, Kobayashi, H., Newcomer, B.R., Wolfe, R.R. Amino acid supplementation decreases plasma and liver triglycerides in elderly. Nutrition. 2009; 25(3):281-8.
    92. Campbell WW, Haub MD, Wolfe RR, Ferrando AA, Sullivan DH, Apolzan JW, Iglay HB. Resistance training preserves fat-free mass without impacting changes in protein metabolism after weight loss in older women. Obesity (Silver Spring). 2009 Jul; 17(7):1332-9. PMID: 19247271.
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    93. Ferrando AA, Paddon- Jones, D., Hays, N.P., Kortebein, P., Ronsen, O., Williams, R., McComb, A., Symons, B., Wolfe, R.R., Evans, W.J. Essential amino acid supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr. 2009.
    94. Ferrando AA, Tipton, K.D., Wolfe, R.R. Essential amino acids for muscle protein accretion. Strength and Conditioning Journal. 2009.
    95. B?rsheim E, Bui QU, Tissier S, Cree MG, R?nsen O, Morio B, Ferrando AA, Kobayashi H, Newcomer BR, Wolfe RR. Amino acid supplementation decreases plasma and liver triacylglycerols in elderly. Nutrition. 2009 Mar; 25(3):281-8. PMID: 19041223.
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    96. Kortebein P, Symons TB, Ferrando A, Paddon-Jones D, Ronsen O, Protas E, Conger S, Lombeida J, Wolfe R, Evans WJ. Functional impact of 10 days of bed rest in healthy older adults. J Gerontol A Biol Sci Med Sci. 2008 Oct; 63(10):1076-81. PMID: 18948558.
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    97. B?rsheim E, Bui QU, Tissier S, Kobayashi H, Ferrando AA, Wolfe RR. Effect of amino acid supplementation on muscle mass, strength and physical function in elderly. Clin Nutr. 2008 Apr; 27(2):189-95. PMID: 18294740.
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    98. Tipton KD, Ferrando AA. Improving muscle mass: response of muscle metabolism to exercise, nutrition and anabolic agents. Essays Biochem. 2008; 44:85-98. PMID: 18384284.
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    99. Ferrando AA, Wolfe RR. Restoration of hormonal action and muscle protein. Crit Care Med. 2007 Sep; 35(9 Suppl):S630-4. PMID: 17713420.
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    100. Uchakin PN, Stowe RP, Paddon-Jones D, Tobin BW, Ferrando AA, Wolfe RR. Cytokine secretion and latent herpes virus reactivation with 28 days of horizontal hypokinesia. Aviat Space Environ Med. 2007 Jun; 78(6):608-12. PMID: 17571663.
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    101. Kortebein P, Ferrando A, Lombeida J, Wolfe R, Evans WJ. Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA. 2007 Apr 25; 297(16):1772-4. PMID: 17456818.
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    102. Kortebein, P., Ferrando AA, Paddon- Jones, D., Ronsen, O., Lobeida, J., Wolfe, R.R., Evans, W.J. Effects of 10 days bed rest in healthy older men and women. Journal American Medical Association. 2007; 16:1772-4.
    103. Raj DS, Adeniyi O, Dominic EA, Boivin MA, McClelland S, Tzamaloukas AH, Morgan N, Gonzales L, Wolfe R, Ferrando A. Amino acid repletion does not decrease muscle protein catabolism during hemodialysis. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1534-42. PMID: 17264222.
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    104. Fitts, R.H., Romatowski, J.G., Peters, J.R., Paddon- Jones, D., Wolfe R.R., Ferrando AA. The deleterious effects of bed rest on human skeletal muscle fibers are exacerbatd by hypercortisolemia and ameliorated by dietary supplementation. American Journal of Physiology Cell Physiology. 2007; (1):C313-20.
    105. Workeneh BT, Rondon-Berrios H, Zhang L, Hu Z, Ayehu G, Ferrando A, Kopple JD, Wang H, Storer T, Fournier M, Lee SW, Du J, Mitch WE. Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J Am Soc Nephrol. 2006 Nov; 17(11):3233-9. PMID: 17005936.
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    106. Paddon-Jones D, Sheffield-Moore M, Cree MG, Hewlings SJ, Aarsland A, Wolfe RR, Ferrando AA. Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. J Clin Endocrinol Metab. 2006 Dec; 91(12):4836-41. PMID: 16984982.
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    107. Ferrando AA, Paddon-Jones D, Wolfe RR. Bed rest and myopathies. Curr Opin Clin Nutr Metab Care. 2006 Jul; 9(4):410-5. PMID: 16778570.
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    108. Stuart CA, Yin D, Howell ME, Dykes RJ, Laffan JJ, Ferrando AA. Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle. Am J Physiol Endocrinol Metab. 2006 Nov; 291(5):E1067-73. PMID: 16803853.
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    109. Pikosky MA, Gaine PC, Martin WF, Grabarz KC, Ferrando AA, Wolfe RR, Rodriguez NR. Aerobic exercise training increases skeletal muscle protein turnover in healthy adults at rest. J Nutr. 2006 Feb; 136(2):379-83. PMID: 16424115.
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    110. Raj DS, Dominic EA, Pai A, Osman F, Morgan M, Pickett G, Shah VO, Ferrando A, Moseley P. Skeletal muscle, cytokines, and oxidative stress in end-stage renal disease. Kidney Int. 2005 Nov; 68(5):2338-44. PMID: 16221238.
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    111. Paddon-Jones D, Wolfe RR, Ferrando AA. Amino acid supplementation for reversing bed rest and steroid myopathies. J Nutr. 2005 Jul; 135(7):1809S-1812S. PMID: 15987870.
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    112. Ferrando AA, Raj D, Wolfe RR. Amino acid control of muscle protein turnover in renal disease. J Ren Nutr. 2005 Jan; 15(1):34-8. PMID: 15648004.
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    113. Paddon-Jones D, Sheffield-Moore M, Urban RJ, Aarsland A, Wolfe RR, Ferrando AA. The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation. J Clin Endocrinol Metab. 2005 Mar; 90(3):1453-9. PMID: 15598679.
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    114. Paddon-Jones D, Sheffield-Moore M, Aarsland A, Wolfe RR, Ferrando AA. Exogenous amino acids stimulate human muscle anabolism without interfering with the response to mixed meal ingestion. Am J Physiol Endocrinol Metab. 2005 Apr; 288(4):E761-7. PMID: 15572657.
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    115. Highstead RG, Tipton KD, Creson DL, Wolfe RR, Ferrando AA. Incidence of associated events during the performance of invasive procedures in healthy human volunteers. J Appl Physiol (1985). 2005 Apr; 98(4):1202-6. PMID: 15563628.
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    116. Paddon-Jones D, Sheffield-Moore M, Urban RJ, Sanford AP, Aarsland A, Wolfe RR, Ferrando AA. Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab. 2004 Sep; 89(9):4351-8. PMID: 15356032.
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    117. Raj DS, Welbourne T, Dominic EA, Waters D, Wolfe R, Ferrando A. Glutamine kinetics and protein turnover in end-stage renal disease. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E37-46. PMID: 15265763.
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    118. Raj DS, Dominic EA, Wolfe R, Shah VO, Bankhurst A, Zager PG, Ferrando A. Coordinated increase in albumin, fibrinogen, and muscle protein synthesis during hemodialysis: role of cytokines. Am J Physiol Endocrinol Metab. 2004 Apr; 286(4):E658-64. PMID: 14722024.
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    119. Raj DS, Shah H, Shah VO, Ferrando A, Bankhurst A, Wolfe R, Zager PG. Markers of inflammation, proteolysis, and apoptosis in ESRD. Am J Kidney Dis. 2003 Dec; 42(6):1212-20. PMID: 14655193.
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    120. Paddon-Jones D, Sheffield-Moore M, Zhang XJ, Volpi E, Wolf SE, Aarsland A, Ferrando AA, Wolfe RR. Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab. 2004 Mar; 286(3):E321-8. PMID: 14583440.
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    121. Raj DS, Zager P, Shah VO, Dominic EA, Adeniyi O, Blandon P, Wolfe R, Ferrando A. Protein turnover and amino acid transport kinetics in end-stage renal disease. Am J Physiol Endocrinol Metab. 2004 Jan; 286(1):E136-43. PMID: 13129859.
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    122. Wolf SE, Thomas SJ, Dasu MR, Ferrando AA, Chinkes DL, Wolfe RR, Herndon DN. Improved net protein balance, lean mass, and gene expression changes with oxandrolone treatment in the severely burned. Ann Surg. 2003 Jun; 237(6):801-10; discussion 810-1. PMID: 12796576.
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    123. Barrow RE, Dasu MR, Ferrando AA, Spies M, Thomas SJ, Perez-Polo JR, Herndon DN. Gene expression patterns in skeletal muscle of thermally injured children treated with oxandrolone. Ann Surg. 2003 Mar; 237(3):422-8. PMID: 12616128.
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    124. Paddon-Jones D, Sheffield-Moore M, Creson DL, Sanford AP, Wolf SE, Wolfe RR, Ferrando AA. Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids. Am J Physiol Endocrinol Metab. 2003 May; 284(5):E946-53. PMID: 12569085.
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    125. Ferrando AA, Sheffield-Moore M, Paddon-Jones D, Wolfe RR, Urban RJ. Differential anabolic effects of testosterone and amino acid feeding in older men. J Clin Endocrinol Metab. 2003 Jan; 88(1):358-62. PMID: 12519877.
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    126. Ferrando AA, Paddon-Jones D, Wolfe RR. Alterations in protein metabolism during space flight and inactivity. Nutrition. 2002 Oct; 18(10):837-41. PMID: 12361775.
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    127. Ferrando AA, Sheffield-Moore M, Yeckel CW, Gilkison C, Jiang J, Achacosa A, Lieberman SA, Tipton K, Wolfe RR, Urban RJ. Testosterone administration to older men improves muscle function: molecular and physiological mechanisms. Am J Physiol Endocrinol Metab. 2002 Mar; 282(3):E601-7. PMID: 11832363.
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