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Murat Gokden

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPathology, College of Medicine
DivisionPathology Clinical
Address7S25 Shorey
324 UAMS Campus Dr.
Mail Slot # 517
Little Rock AR 72205
Phone501-526-7746
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    Collapse Overview 
    Collapse overview
    Academic Appointment
    • Professor of Pathology
    Department - Pathology

    Education
    • Fellowship: Cytopathology-University of Arkansas for Medical Sciences
    • Fellowship: Surgical Pathology-University of Texas, MD Anderson Cancer Center
    • Fellowship: Neuropathology-Washington University in St. Louis
    • Residency: Anatomic Pathology- Washington University in St. Louis
    • Medical School: Dokuz Eylul Medical School, Izmir, Turkey
    Professional Certifications
    • American Board of Pathology-Anatomic Pathology
    • American Board of Pathology-Neuropathology
    • American Board of Pathology-Cytopathology


    Collapse Affiliation 
    Collapse member of
    United States and Canadian Academy of Pathology (USCAP)
    American Association of Neuropathologists (AANP)
    Society for Neuroscience Arkansas Chapter
    Arkansas Medical Society
    Collapse clinical activities
    Neuropathologist, UAMS
    Neuropathologist, ACH
    Consultant Neuropathologist, Arkansas State Crime Laboratory

    Collapse Biography 
    Collapse Leadership and Administrative Roles
    Overview of all neuropathology service and laboratory operations at the Dept. of Pathology, UAMS

    Overview of all neuropathology service and laboratory operations at the Dept. of Pathology, ACH


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Gilbert AR, Zaky W, Gokden M, Fuller CE, Ocal E, Leeds NE, Fuller GN. Extending the Neuroanatomic Territory of Diffuse Midline Glioma, K27M Mutant: Pineal Region Origin. Pediatr Neurosurg. 2018; 53(1):59-63. PMID: 29131126.
      View in: PubMed
    2. Gokden M. If it is Not a Glioblastoma, Then What is it? A Differential Diagnostic Review. Adv Anat Pathol. 2017 Nov; 24(6):379-391. PMID: 28885262.
      View in: PubMed
    3. Elwy R, Gokden M, Cai R. Emergency Optic Canal Decompression for Vision Salvage in Fibrous Dysplasia. World Neurosurg. 2018 Jan; 109:134-137. PMID: 28958926.
      View in: PubMed
    4. Albert GW, Gokden M. Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature. J Neurosurg Pediatr. 2017 Mar; 19(3):339-348. PMID: 28106515.
      View in: PubMed
    5. Mohan M, Gokden M, Gokden N, Schinke C. A Case of Cardiac Light Chain Deposition Disease in a Patient with Solitary Plasmacytoma. Am J Case Rep. 2016 Mar 18; 17:173-6. PMID: 26988342; PMCID: PMC4801155.
    6. Abraham RR, Pollitzer RE, Gokden M, Goulden PA. Spontaneous pituitary apoplexy during the second trimester of pregnancy, with sensory loss. BMJ Case Rep. 2016 Feb 16; 2016. PMID: 26884071.
      View in: PubMed
    7. Samanta D, Gokden M, Albert GW. Absence of seizures in Rasmussen encephalitis with active inflammation. J Clin Neurosci. 2016 Jun; 28:175-8. PMID: 26775150.
      View in: PubMed
    8. Jiwani S, Gokden M, Lindberg M, Ali S, Jeffus S. Fine-needle aspiration cytology of epithelioid malignant peripheral nerve sheath tumor: A case report and review of the literature. Diagn Cytopathol. 2016 Mar; 44(3):226-31. PMID: 26646298.
      View in: PubMed
    9. Kaskas NM, Kern M, Johnson A, Hughes MP, Hardee M, Day J, Gokden M, Shalin SC, Gao L. A Case of Cutaneous Rosai-Dorfman Disease with underlying calvarial involvement and absence of BRAFV600E mutation. JAAD Case Rep. 2015 Nov 01; 1(6):408-411. PMID: 26858984.
      View in: PubMed
    10. Gupta HV, Samant R, Gokden M, Lee RW, Sahaya K, Virmani T. Clinical Reasoning: A 73-year-old man with diplopia and ataxia. Neurology. 2015 Sep 29; 85(13):e96-100. PMID: 26416806.
      View in: PubMed
    11. Gokden M, Ariza A, Arnaoutakis K. Molecular Markers in the Diagnosis and Treatment of Cancer. Biomed Res Int. 2015; 2015:105217. PMID: 26451364; PMCID: PMC4584220.
    12. Gupta HV, Gokden M, Ramakrishnaiah RH, Archer RL. Progressive multifocal leukoencephalopathy mimicking glioma in a patient with idiopathic CD4 lymphocytopenia. Acta Neurol Belg. 2016 Sep; 116(3):391-4. PMID: 26319126.
      View in: PubMed
    13. Bradley LH, Burton M, Gokden M, Serletis D. Prostate carcinoma mimicking a sphenoid wing meningioma. Int J Surg Case Rep. 2015; 15:63-5. PMID: 26318129; PMCID: PMC4601959.
    14. Mobley BC, Kumar M, Sanger WG, Nelson M, Nickols HH, Chambless LB, Gokden M. Papillary tumor of the pineal region with synchronous suprasellar focus and novel cytogenetic features. Hum Pathol. 2015 Aug; 46(8):1232-6. PMID: 26068071.
      View in: PubMed
    15. Abdallah AO, Herlopian A, Ravilla R, Bansal M, Chandra-Reddy S, Mahmoud F, Ong S, Gokden M, Hutchins L. Ipilimumab-induced necrotic myelopathy in a patient with metastatic melanoma: A case report and review of literature. J Oncol Pharm Pract. 2016 Jun; 22(3):537-42. PMID: 25712627.
      View in: PubMed
    16. Aboud E, Abolfotoh M, Pravdenkova S, Gokoglu A, Gokden M, Al-Mefty O. Giant intracranial epidermoids: is total removal feasible? J Neurosurg. 2015 Apr; 122(4):743-56. PMID: 25594324.
      View in: PubMed
    17. Phillips BC, Gokden M, Petersen E. Granulomatous encephalitis due to Balamuthia mandrillaris is not limited to immune-compromised patients. Clin Neurol Neurosurg. 2013 Jul; 115(7):1102-4. PMID: 22921039.
      View in: PubMed
    18. Elbabaa SK, Gokden M, Crawford JR, Kesari S, Saad AG. Radiation-associated meningiomas in children: clinical, pathological, and cytogenetic characteristics with a critical review of the literature. J Neurosurg Pediatr. 2012 Oct; 10(4):281-90. PMID: 22900483.
      View in: PubMed
    19. Yaghi SR, Sethi H, Gokden M, Harik SI. "Tumefactive demyelineation of the spinal cord: a case report". Acta Neurologica Belgica. 2011.
    20. Yahgi S, Ikard C, Al-Lahham T, Gokden M, Moore SA, Gundogdu B. "Dysferlinopathy is a rare cause of amyloid deposits in the muscle". J Clin Neuromus Dis. 2011; 186.
    21. Vogel H, McKenney JK, Bangs CD, Edwards MSB, Fischer PG, Callahan K, Gokden M, Mobley BC. "Poorly differentiated chordomas. Diagnostic utility of immunohistochemistry for brachyuyr and SMARCB1/IMI1". 2011.
    22. Sharma SG, Gokden M, McKenney JK, Phan DC, Cox RM, Kelly T, Gokden N. The utility of PAX-2 and renal cell carcinoma marker immunohistochemistry in distinguishing papillary renal cell carcinoma from nonrenal cell neoplasms with papillary features. Appl Immunohistochem Mol Morphol. 2010 Dec; 18(6):494-8. PMID: 21102195.
      View in: PubMed
    23. Mobley BC, McKenney JK, Bangs CD, Callahan K, Yeom KW, Schneppenheim R, Hayden MG, Cherry AM, Gokden M, Edwards MS, Fisher PG, Vogel H. Loss of SMARCB1/INI1 expression in poorly differentiated chordomas. Acta Neuropathol. 2010 Dec; 120(6):745-53. PMID: 21057957.
      View in: PubMed
    24. Gokden M. Methods of Cancer Diagnosis: Therapy and Prognosis: Brain Cancer. "Pituitary Adenoma and Cranoiopharyngioma: an Overview". 2010.
    25. Gokden M, Al-Hinti JT, Harik SI. Peripheral nervous system pathology in fragile X ataxia/tremor syndrome (FXTAS). Neuropathology. 2009.
    26. Gokden M, Mrak RE. Pituitary adenoma with craniopharyngioma component. Hum Pathol. 2009 Aug; 40(8):1189-93. PMID: 19427020.
      View in: PubMed
    27. Scheithauer BW, Erdogan S, Rodriguez FJ, Burger PC, Woodruff JM, Kros JM, Gokden M, Spinner RJ. Malignant peripheral nerve sheath tumors of cranial nerves and intracranial contents: a clinicopathologic study of 17 cases. Am J Surg Pathol. 2009 Mar; 33(3):325-38. PMID: 19065105.
      View in: PubMed
    28. De Las Casas, LE, Boman, D, Gokden M. Evaluation of intraoperative cytology preparations (ICP) to differentiate central neurocytoma (CN) from oligodendroglioma (OL) and ependymoma (EP). Modern Pathol 23 (suppl 1): 90A and Lab Invest 90 (suppl 1): 90A. 2009.
    29. Gokden M. Staining intensity in the evaluation of proliferation index. J Neuropathol Exper Neurol. 2009; 586.
    30. Gokden M, Gokden N. Cytopathologic Diagnosis of Metastatic Renal Cell Carcinoma Using Immunohistochemistry. American Society for Clinical Pathology (ASCP), Check Sample Series. 2009.
    31. Gokden M. Staining intensity in the evaluation of proliferation index. 85th Annual Meeting of the American Association of Neuropathologists. 2009.
    32. Phan DC, Sharma SG, Cox RM, Gokden M, McKenney JK, Gokden N. The utility of PAX2 and renal cell carcinoma marker immunohistochemistry in distinguishing papillary renal cell carcinoma from non-renal neoplasms with papillary features. 98th Annual Meeting of the United States and Canadian Academy of Pathology. 2009.
    33. Gokden N, Gokden M, Phan DC, McKenney JK. The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics: an immunohistochemical study with comparison to renal cell carcinoma marker. Am J Surg Pathol. 2008 Oct; 32(10):1462-7. PMID: 18685487.
      View in: PubMed
    34. Gokden N, Kemp SA, Gokden M. The utility of Pax-2 as an immunohistochemical marker for renal cell carcinoma in cytopathology. Diagn Cytopathol. 2008 Jul; 36(7):473-7. PMID: 18528893.
      View in: PubMed
    35. Gokden M, Al-Hinti JT, Harik SI. Peripheral nervous system pathology in fragile X tremor/ataxia syndrome (FXTAS). Neuropathology. 2009 Jun; 29(3):280-4. PMID: 18627480.
      View in: PubMed
    36. Sahin FK, Koken G, Cosar E, Koken R, Sahin O, Gokden M. A prenatal diagnosed case of primitive neuroectodermal tumor. Fetal Diagn Ther. 2008; 23(4):267-70. PMID: 18417992.
      View in: PubMed
    37. Sahin FK, Koken G, Cosar E, Koken R, Sahin O, Gokden M. A prenatally diagnosed case of primitive neuroectodermal tumor. Fetal Diagn Ther. 2008; 23:267-270.
    38. Almefty K, Pravdenkova S, Colli BO, Al-Mefty O, Gokden M. Chordoma and chondrosarcoma: similar, but quite different, skull base tumors. Cancer. 2007 Dec 01; 110(11):2457-67. PMID: 17894390.
      View in: PubMed
    39. Gökden N, Greene GF, Bayer-Garner IB, Spencer HJ, Sanderson RD, Gökden M. Expression of CD138 (Syndecan-1) in renal cell carcinoma is reduced with increasing nuclear grade. Appl Immunohistochem Mol Morphol. 2006 Jun; 14(2):173-7. PMID: 16785785.
      View in: PubMed
    40. Cetin N, Dienel G, Gokden M. CD117 expression in glial tumors. J Neurooncol. 2005 Nov; 75(2):195-202. PMID: 16132504.
      View in: PubMed
    41. Challagundla S, Gokden M, Viswamitra S, Kohli M. Orbital metastasis from prostate cancer: an atypical case of neuroendocrine dedifferentiation during progression from hormone-sensitive to refractory stage. Clin Prostate Cancer. 2005 Sep; 4(2):134-7. PMID: 16197616.
      View in: PubMed
    42. Gokden M, Shinde A. Recent immunohistochemical markers in the differential diagnosis of primary and metastatic carcinomas of the liver. Diagn Cytopathol. 2005 Sep; 33(3):166-72. PMID: 16078249.
      View in: PubMed
    43. Santin AD, Zhan F, Bellone S, Palmieri M, Cane S, Bignotti E, Anfossi S, Gokden M, Dunn D, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J, Pecorelli S. Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy. Int J Cancer. 2004 Oct 20; 112(1):14-25. PMID: 15305371.
      View in: PubMed
    44. De Las Casas LE, Gokden M, Mukunyadzi P, White P, Baker SJ, Hermonat PL, You H, Korourian S, Malak SF, Miranda RN. A morphologic and statistical comparative study of small-cell carcinoma and non-Hodgkin's lymphoma in fine-needle aspiration biopsy material from lymph nodes. Diagn Cytopathol. 2004 Oct; 31(4):229-34. PMID: 15452900.
      View in: PubMed
    45. De Las Casas LE, Gokden M, Baker SJ, Korourian S, Hermonat PL, You H, Miranda RN, Shalkham JE, O'Brien LA, Mukunyadzi P. Malignant melanoma metastatic to the liver. A cytomorphologic comparative study to identify reproducible diagnostic criteria. Acta Cytol. 2004 Jan-Feb; 48(1):32-8. PMID: 14969178.
      View in: PubMed
    46. Bellone S, Palmieri M, Gokden M, Joshua J, Roman JJ, Pecorelli S, Cannon MJ, Santin AD. Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy. Gynecol Oncol. 2003 Oct; 91(1):231-40. PMID: 14529687.
      View in: PubMed
    47. Gokden N, Mukunyadzi P, James JD, Gokden M. Diagnostic utility of renal cell carcinoma marker in cytopathology. Appl Immunohistochem Mol Morphol. 2003 Jun; 11(2):116-9. PMID: 12777993.
      View in: PubMed
    48. Cetin N, Ball K, Gokden M, Cruz NF, Dienel GA. Effect of reactive cell density on net [2-14C]acetate uptake into rat brain: labeling of clusters containing GFAP+- and lectin+-immunoreactive cells. Neurochem Int. 2003 Apr; 42(5):359-74. PMID: 12510019.
      View in: PubMed
    49. Dienel GA, Cruz NF, Ball K, Popp D, Gokden M, Baron S, Wright D, Wenger GR. Behavioral training increases local astrocytic metabolic activity but does not alter outcome of mild transient ischemia. Brain Res. 2003 Jan 31; 961(2):201-12. PMID: 12531487.
      View in: PubMed
    50. Santin AD, Bellone S, Gokden M, Cannon MJ, Parham GP. Vaccination with HPV-18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer. N Engl J Med. 2002 May 30; 346(22):1752-3. PMID: 12037163.
      View in: PubMed
    51. Hameed A, Gokden M, Hanna EY. Fine-needle aspiration cytology of a primary ectopic meningioma. Diagn Cytopathol. 2002 May; 26(5):297-300. PMID: 11992371.
      View in: PubMed
    52. Santin AD, Bellone S, Gokden M, Palmieri M, Dunn D, Agha J, Roman JJ, Hutchins L, Pecorelli S, O'Brien T, Cannon MJ, Parham GP. Overexpression of HER-2/neu in uterine serous papillary cancer. Clin Cancer Res. 2002 May; 8(5):1271-9. PMID: 12006548.
      View in: PubMed
    53. Leonard J, Gokden M, Kyriakos M, Derdeyn CP, Rich KM. Malignant giant-cell tumor of the parietal bone: case report and review of the literature. Neurosurgery. 2001; 48(2):424 - 429.
    54. Sorensen DM, Gokden M, El-Naggar A, Byers RM. Quiz case 1. Periosteal osteosarcoma (PO) of the mandible. Arch Otolaryngol Head Neck Surg. 2000; 126(4):550, 552 - .
    55. Ojemann JG, Moran CJ, Gokden M, Dacey RG. Sagittal sinus occlusion by intraluminal dural cysts. Report of two cases. J Neurosurg. 1999; 91(5):867 - 870.
    56. Racette BA, Gokden MS, Tychsen LS, Perlmutter JS. Convergence insufficiency in idiopathic Parkinson's disease responsive to levodopa. Strabismus. 1999 Sep; 7(3):169-74. PMID: 10520242.
      View in: PubMed
    57. Selznick LA, Holtzman DM, Han BH, Gokden M, Srinivasan AN, Johnson EM, Roth KA. In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease. J Neuropathol Exp Neurol. 1999; 58(9):1020 - 1026.
    58. Khoury H, Adkins D, Brown R, Goodnough L, Gokden M, Roberts T, Storch G, DiPersio J. Successful treatment of cerebral toxoplasmosis in a marrow transplant recipient: contribution of a PCR test in diagnosis and early detection. Bone Marrow Transplant. 1999; 23(4):409 - 411.
    59. Sherburn EW, Bahn MM, Gokden M, Silbergeld DL, Rich KM. Dysembryoplastic neuroepithelial tumor and oligodendroglioma: the diagnostic value of magnetic resonance spectroscopy. Case report and review of the literature. Neurosurg Focus. 1998; 4(4):e6 - .
    60. Roth KA, Brenner JW, Selznick LA, Gokden M, Lorenz RG. Enzyme-based antigen localization and quantitation in cell and tissue samples (Midwestern assay). J Histochem Cytochem. 1997; 45(12):1629 - 1641.
    61. Gokden M, Roth KA, Carroll SL, Wick MR, Schmidt RE. Clear cell neoplasms and pseudoneoplastic lesions of the central nervous system. Semin Diagn Pathol. 1997; 14(4):253 - 269.
    62. Akgur FM, Olguner M, Yenici O, Gokden M, Aktug T, Yilmaz M, Atac G. The effect of allopurinol pretreatment on intestinal hypoperfusion encountered after correction of intestinal volvulus. J Pediatr Surg. 1996; 31(9):1205 - 1207.
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