 Glypicans
"Glypicans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored, cell-surface heparan sulfate proteoglycans that may play a role in CELL GROWTH PROCESSES and CELL DIFFERENTIATION by modulating ligand-receptor interactions.
| Descriptor ID |
D053673
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| MeSH Number(s) |
D12.776.395.550.448.500 D12.776.395.650.350.249 D12.776.543.484.500.550 D12.776.543.550.418.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glypicans".
Below are MeSH descriptors whose meaning is more specific than "Glypicans".
This graph shows the total number of publications written about "Glypicans" by people in UAMS Profiles by year, and whether "Glypicans" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glypicans" by people in Profiles over the past ten years.
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Ghosh S, Huda P, Fletcher N, Campbell D, Thurecht KJ, Walsh B. Clinical development of an anti-GPC-1 antibody for the treatment of cancer. Expert Opin Biol Ther. 2022 05; 22(5):603-613.
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Polikarpov DM, Campbell DH, Zaslavsky AB, Lund ME, Wu A, Lu Y, Palapattu GS, Walsh BJ, Zvyagin AV, Gillatt DA. Glypican-1 as a target for fluorescence molecular imaging of bladder cancer. Int J Urol. 2021 12; 28(12):1290-1297.
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Lund ME, Howard CB, Thurecht KJ, Campbell DH, Mahler SM, Walsh BJ. A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cells. BMC Cancer. 2020 Dec 10; 20(1):1214.
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Lund ME, Campbell DH, Walsh BJ. The Role of Glypican-1 in the Tumour Microenvironment. Adv Exp Med Biol. 2020; 1245:163-176.
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Polikarpov D, Liang L, Care A, Sunna A, Campbell D, Walsh B, Balalaeva I, Zvyagin A, Gillatt D, Guryev E. Functionalized Upconversion Nanoparticles for Targeted Labelling of Bladder Cancer Cells. Biomolecules. 2019 12 03; 9(12).
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Campbell DH, Lund ME, Nocon AL, Cozzi PJ, Frydenberg M, De Souza P, Schiller B, Beebe-Dimmer JL, Ruterbusch JJ, Walsh BJ. Detection of glypican-1 (GPC-1) expression in urine cell sediments in prostate cancer. PLoS One. 2018; 13(4):e0196017.
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Sayyadi N, Justiniano I, Connally RE, Zhang R, Shi B, Kautto L, Everest-Dass AV, Yuan J, Walsh BJ, Jin D, Willows RD, Piper JA, Packer NH. Sensitive Time-Gated Immunoluminescence Detection of Prostate Cancer Cells Using a TEGylated Europium Ligand. Anal Chem. 2016 10 04; 88(19):9564-9571.
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