 DNA Fragmentation
"DNA Fragmentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.
| Descriptor ID |
D053938
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| MeSH Number(s) |
G05.355.180.230
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "DNA Fragmentation".
Below are MeSH descriptors whose meaning is more specific than "DNA Fragmentation".
This graph shows the total number of publications written about "DNA Fragmentation" by people in UAMS Profiles by year, and whether "DNA Fragmentation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2019 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2015 | 1 | 2 | 3 | | 2014 | 1 | 0 | 1 | | 2013 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2011 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2007 | 0 | 4 | 4 | | 2006 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 5 | 5 | | 2003 | 0 | 2 | 2 | | 2002 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 1997 | 0 | 2 | 2 |
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Below are the most recent publications written about "DNA Fragmentation" by people in Profiles over the past ten years.
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Basnakian AG, Moore CL. Apoptotic DNase network: Mutual induction and cooperation among apoptotic endonucleases. J Cell Mol Med. 2021 07; 25(14):6496-6499.
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Moore CL, Savenka AV, Basnakian AG. TUNEL Assay: A Powerful Tool for Kidney Injury Evaluation. Int J Mol Sci. 2021 Jan 02; 22(1).
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Fahmi T, Wang X, Zhdanov DD, Islam I, Apostolov EO, Savenka AV, Basnakian AG. DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity. Int J Mol Sci. 2020 Nov 17; 21(22).
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Del Valle L, Sweet T, Parker-Struckhoff A, Perez-Liz G, Pi?a-Oviedo S. JCPyV T-Antigen Activation of the Anti-Apoptotic Survivin Promoter-Its Role in the Development of Progressive Multifocal Leukoencephalopathy. Viruses. 2020 11 03; 12(11).
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Rosas-Hernandez H, Escudero-Lourdes C, Ramirez-Lee MA, Cuevas E, Lantz SM, Imam SZ, Majeed W, Bourdo SE, Paule MG, Biris AS, Ali SF. Cytotoxicity profile of pristine graphene on brain microvascular endothelial cells. J Appl Toxicol. 2019 07; 39(7):966-973.
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Urbaniak A, Delgado M, Antoszczak M, Huczynski A, Chambers TC. Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro. Biomed Pharmacother. 2018 Mar; 99:384-390.
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Zeng H, Taussig DP, Cheng WH, Johnson LK, Hakkak R. Butyrate Inhibits Cancerous HCT116 Colon Cell Proliferation but to a Lesser Extent in Noncancerous NCM460 Colon Cells. Nutrients. 2017 Jan 01; 9(1).
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Bose C, Shah SV, Karaduta OK, Kaushal GP. Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury. PLoS One. 2016; 11(12):e0165576.
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Weemhoff JL, Woolbright BL, Jenkins RE, McGill MR, Sharpe MR, Olson JC, Antoine DJ, Curry SC, Jaeschke H. Plasma biomarkers to study mechanisms of liver injury in patients with hypoxic hepatitis. Liver Int. 2017 03; 37(3):377-384.
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Permenter J, Ishwar A, Rounsavall A, Smith M, Faske J, Sailey CJ, Alfaro MP. Quantitative analysis of genomic DNA degradation in whole blood under various storage conditions for molecular diagnostic testing. Mol Cell Probes. 2015 Dec; 29(6):449-453.
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Du K, McGill MR, Xie Y, Bajt ML, Jaeschke H. Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity. Food Chem Toxicol. 2015 Jul; 81:62-70.
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Zhdanov DD, Fahmi T, Wang X, Apostolov EO, Sokolov NN, Javadov S, Basnakian AG. Regulation of Apoptotic Endonucleases by EndoG. DNA Cell Biol. 2015 May; 34(5):316-26.
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McGill MR, Staggs VS, Sharpe MR, Lee WM, Jaeschke H. Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome. Hepatology. 2014 Oct; 60(4):1336-45.
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