 Tamoxifen
"Tamoxifen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
| Descriptor ID |
D013629
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| MeSH Number(s) |
D02.455.426.559.389.150.700.900
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| Concept/Terms |
Soltamox- Soltamox
- Savient brand of Tamoxifen Citrate
ICI-46474- ICI-46474
- ICI 46474
- ICI46474
- ICI-46,474
- ICI 46,474
- ICI46,474
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Below are MeSH descriptors whose meaning is more general than "Tamoxifen".
Below are MeSH descriptors whose meaning is more specific than "Tamoxifen".
This graph shows the total number of publications written about "Tamoxifen" by people in UAMS Profiles by year, and whether "Tamoxifen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 2 | 2 | | 2019 | 0 | 2 | 2 | | 2018 | 1 | 1 | 2 | | 2017 | 0 | 2 | 2 | | 2016 | 2 | 2 | 4 | | 2015 | 0 | 1 | 1 | | 2014 | 2 | 1 | 3 | | 2013 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2010 | 2 | 1 | 3 | | 2008 | 1 | 3 | 4 | | 2007 | 3 | 2 | 5 | | 2006 | 1 | 1 | 2 | | 2005 | 3 | 2 | 5 | | 2004 | 3 | 1 | 4 | | 2003 | 1 | 1 | 2 | | 2002 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 1999 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Tamoxifen" by people in Profiles over the past ten years.
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Englund DA, Figueiredo VC, Dungan CM, Murach KA, Peck BD, Petrosino JM, Brightwell CR, Dupont AM, Neal AC, Fry CS, Accornero F, McCarthy JJ, Peterson CA. Satellite Cell Depletion Disrupts Transcriptional Coordination and Muscle Adaptation to Exercise. Function (Oxf). 2021; 2(1):zqaa033.
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Nayyar A, Strassle PD, Iles K, Jameison D, Jadi J, McGuire KP, Gallagher KK. Survival Outcomes of Early-Stage Hormone Receptor-Positive Breast Cancer in Elderly Women. Ann Surg Oncol. 2020 Nov; 27(12):4853-4860.
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Girer NG, Carter D, Bhattarai N, Mustafa M, Denner L, Porter C, Elferink CJ. Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21. Int J Mol Sci. 2019 Feb 22; 20(4).
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Miah S, Bagu E, Goel R, Ogunbolude Y, Dai C, Ward A, Vizeacoumar FS, Davies G, Vizeacoumar FJ, Anderson D, Lukong KE. Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells. BMC Cancer. 2019 Jan 16; 19(1):78.
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Franks LN, Ford BM, Fujiwara T, Zhao H, Prather PL. The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects. Toxicol Appl Pharmacol. 2018 08 15; 353:31-42.
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Srivastava R, Cornett LE, Chaturvedi CM. Impact of estrogen and photoperiod on arginine vasotocin and VT3 receptor expression in the shell gland of quail. Front Biosci (Schol Ed). 2018 06 01; 10(2):372-385.
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Fader AN, Bergstrom J, Jernigan A, Tanner EJ, Roche KL, Stone RL, Levinson KL, Ricci S, Wethingon S, Wang TL, Shih IM, Yang B, Zhang G, Armstrong DK, Gaillard S, Michener C, DeBernardo R, Rose PG. Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival? Gynecol Oncol. 2017 10; 147(1):85-91.
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McCarthy JJ, Dupont-Versteegden EE, Fry CS, Murach KA, Peterson CA. Methodological issues limit interpretation of negative effects of satellite cell depletion on adult muscle hypertrophy. Development. 2017 04 15; 144(8):1363-1365.
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Ford BM, Franks LN, Radominska-Pandya A, Prather PL. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016; 11(12):e0167240.
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Kinney MC, Dayanidhi S, Dykstra PB, McCarthy JJ, Peterson CA, Lieber RL. Reduced skeletal muscle satellite cell number alters muscle morphology after chronic stretch but allows limited serial sarcomere addition. Muscle Nerve. 2017 03; 55(3):384-392.
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Fry CS, Kirby TJ, Kosmac K, McCarthy JJ, Peterson CA. Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy. Cell Stem Cell. 2017 01 05; 20(1):56-69.
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Myers AP, Filiaci VL, Zhang Y, Pearl M, Behbakht K, Makker V, Hanjani P, Zweizig S, Burke JJ, Downey G, Leslie KK, Van Hummelen P, Birrer MJ, Fleming GF. Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study. Gynecol Oncol. 2016 Apr; 141(1):43-8.
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Lee JD, Fry CS, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):461-7.
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de Conti A, Tryndyak V, Churchwell MI, Melnyk S, Latendresse JR, Muskhelishvili L, Beland FA, Pogribny IP. Genotoxic, epigenetic, and transcriptomic effects of tamoxifen in mouse liver. Toxicology. 2014 Nov 05; 325:12-20.
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Greer AK, Dates CR, Starlard-Davenport A, Edavana VK, Bratton SM, Dhakal IB, Finel M, Kadlubar SA, Radominska-Pandya A. A potential role for human UDP-glucuronosyltransferase 1A4 promoter single nucleotide polymorphisms in the pharmacogenomics of tamoxifen and its derivatives. Drug Metab Dispos. 2014 Sep; 42(9):1392-400.
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Chau YY, Bandiera R, Serrels A, MartÃnez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N. Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source. Nat Cell Biol. 2014 Apr; 16(4):367-75.
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Fry CS, Lee JD, Jackson JR, Kirby TJ, Stasko SA, Liu H, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy. FASEB J. 2014 Apr; 28(4):1654-65.
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Prather PL, FrancisDevaraj F, Dates CR, Greer AK, Bratton SM, Ford BM, Franks LN, Radominska-Pandya A. CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen. Biochem Biophys Res Commun. 2013 Nov 15; 441(2):339-43.
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