Mitotane
"Mitotane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
| Descriptor ID |
D008939
|
| MeSH Number(s) |
D02.455.526.439.681
|
| Concept/Terms |
Mitotane- Mitotane
- ortho,para-DDD
- ortho,para DDD
- Mytotan
- o,p-DDD
Lysodren- Lysodren
- Bristol-Myers Squibb Brand of Mitotane
- Bristol Myers Squibb Brand of Mitotane
|
Below are MeSH descriptors whose meaning is more general than "Mitotane".
Below are MeSH descriptors whose meaning is more specific than "Mitotane".
This graph shows the total number of publications written about "Mitotane" by people in UAMS Profiles by year, and whether "Mitotane" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitotane" by people in Profiles over the past ten years.
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Dickson PV, Kim L, Yen TWF, Yang A, Grubbs EG, Patel D, Sol?rzano CC. Adjuvant and Neoadjuvant Therapy, Treatment for Advanced Disease, and Genetic Considerations for Adrenocortical Carcinoma: An Update from the SSO Endocrine and Head and Neck Disease Site Working Group. Ann Surg Oncol. 2018 Nov; 25(12):3453-3459.