 5-Methylcytosine
"5-Methylcytosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.
| Descriptor ID |
D044503
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| MeSH Number(s) |
D03.383.742.698.421.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "5-Methylcytosine".
Below are MeSH descriptors whose meaning is more specific than "5-Methylcytosine".
This graph shows the total number of publications written about "5-Methylcytosine" by people in UAMS Profiles by year, and whether "5-Methylcytosine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 | | 2016 | 2 | 0 | 2 | | 2014 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "5-Methylcytosine" by people in Profiles over the past ten years.
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Choudhury SR, Ordaz J, Lo CL, Damayanti NP, Zhou F, Irudayaraj J. From the Cover: Zinc oxide Nanoparticles-Induced Reactive Oxygen Species Promotes Multimodal Cyto- and Epigenetic Toxicity. Toxicol Sci. 2017 03 01; 156(1):261-274.
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Xu Z, Taylor JA, Leung YK, Ho SM, Niu L. oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA. Bioinformatics. 2016 12 01; 32(23):3667-3669.
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Toraño EG, Bayón GF, Del Real Á, Sierra MI, García MG, Carella A, Belmonte T, Urdinguio RG, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Fraga MF, Fernández AF. Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells. J Transl Med. 2016 07 08; 14(1):207.
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James SJ, Shpyleva S, Melnyk S, Pavliv O, Pogribny IP. Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum. Transl Psychiatry. 2014 Oct 07; 4:e460.
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Miousse IR, Chalbot MC, Aykin-Burns N, Wang X, Basnakian A, Kavouras IG, Koturbash I. Epigenetic alterations induced by ambient particulate matter in mouse macrophages. Environ Mol Mutagen. 2014 Jun; 55(5):428-35.
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Huang WY, Su LJ, Hayes RB, Moore LE, Katki HA, Berndt SI, Weissfeld JL, Yegnasubramanian S, Purdue MP. Prospective study of genomic hypomethylation of leukocyte DNA and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev. 2012 Nov; 21(11):2014-21.
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