 Atherosclerosis
"Atherosclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Descriptor ID |
D050197
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| MeSH Number(s) |
C14.907.137.126.307
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Atherosclerosis".
Below are MeSH descriptors whose meaning is more specific than "Atherosclerosis".
This graph shows the total number of publications written about "Atherosclerosis" by people in UAMS Profiles by year, and whether "Atherosclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 2 | 0 | 2 | | 2018 | 3 | 2 | 5 | | 2017 | 3 | 0 | 3 | | 2016 | 7 | 3 | 10 | | 2015 | 7 | 1 | 8 | | 2014 | 10 | 2 | 12 | | 2013 | 6 | 3 | 9 | | 2012 | 2 | 2 | 4 | | 2011 | 16 | 0 | 16 | | 2010 | 9 | 4 | 13 | | 2009 | 4 | 4 | 8 | | 2008 | 6 | 1 | 7 | | 2007 | 5 | 4 | 9 | | 2006 | 6 | 4 | 10 | | 2005 | 5 | 1 | 6 | | 2004 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Atherosclerosis" by people in Profiles over the past ten years.
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Sriprasert I, Hodis HN, Karim R, Stanczyk FZ, Shoupe D, Henderson VW, Mack WJ. Differential Effect of Plasma Estradiol on Subclinical Atherosclerosis Progression in Early vs Late Postmenopause. J Clin Endocrinol Metab. 2019 02 01; 104(2):293-300.
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Kattoor AJ, Kanuri SH, Mehta JL. Role of Ox-LDL and LOX-1 in Atherogenesis. Curr Med Chem. 2019; 26(9):1693-1700.
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Hou TT, Lin F, Bai S, Cleves MA, Xu HM, Lou XY. Generalized multifactor dimensionality reduction approaches to identification of genetic interactions underlying ordinal traits. Genet Epidemiol. 2019 02; 43(1):24-36.
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Ding Z, Liu S, Wang X, Theus S, Deng X, Fan Y, Zhou S, Mehta JL. PCSK9 regulates expression of scavenger receptors and ox-LDL uptake in macrophages. Cardiovasc Res. 2018 07 01; 114(8):1145-1153.
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Pothineni NVKC, Mehta JL. Can certain infections protect against atherosclerosis? Eur Heart J. 2018 05 07; 39(18):1654.
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Dai Y, Wu X, Dai D, Li J, Mehta JL. MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1. Redox Biol. 2018 06; 16:255-262.
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Pang H, Han B, Fu Q, Hao L, Zong Z. Association between homocysteine and conventional predisposing factors on risk of stroke in patients with hypertension. Sci Rep. 2018 03 01; 8(1):3900.
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Pothineni NVK, Subramany S, Kuriakose K, Shirazi LF, Romeo F, Shah PK, Mehta JL. Infections, atherosclerosis, and coronary heart disease. Eur Heart J. 2017 Nov 14; 38(43):3195-3201.
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Kattoor AJ, Pothineni NVK, Palagiri D, Mehta JL. Oxidative Stress in Atherosclerosis. Curr Atheroscler Rep. 2017 Sep 18; 19(11):42.
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Pothineni NVK, Karathanasis SK, Ding Z, Arulandu A, Varughese KI, Mehta JL. LOX-1 in Atherosclerosis and Myocardial Ischemia: Biology, Genetics, and Modulation. J Am Coll Cardiol. 2017 Jun 06; 69(22):2759-2768.
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Bose C, Shah SV, Karaduta OK, Kaushal GP. Carbamylated Low-Density Lipoprotein (cLDL)-Mediated Induction of Autophagy and Its Role in Endothelial Cell Injury. PLoS One. 2016; 11(12):e0165576.
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Chung J, Modrall JG, Knowles M, Xiang Q, Lavery LA, Timaran CH, Valentine RJ. Arteriographic Patterns of Atherosclerosis and the Association between Diabetes Mellitus and Ethnicity in Chronic Critical Limb Ischemia. Ann Vasc Surg. 2017 Apr; 40:198-205.
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Cariou B, Ding Z, Mehta JL. PCSK9 and atherosclerosis: Beyond LDL-cholesterol lowering. Atherosclerosis. 2016 10; 253:275-277.
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Adedinsewo D, Taka N, Agasthi P, Sachdeva R, Rust G, Onwuanyi A. Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults: National Health and Nutrition Examination Survey, 2011-2012. Clin Cardiol. 2016 Sep; 39(9):491-6.
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Jensen HA, Mehta JL. Endothelial cell dysfunction as a novel therapeutic target in atherosclerosis. Expert Rev Cardiovasc Ther. 2016 Sep; 14(9):1021-33.
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Zhou H, Ran Y, Da Q, Shaw TS, Shang D, Reddy AK, López JA, Ballantyne CM, Ware J, Wu H, Peng Y. Defective Association of the Platelet Glycoprotein Ib-IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma Formation. J Immunol. 2016 07 01; 197(1):288-95.
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Hodis HN, Mack WJ, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31; 374(13):1221-31.
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Liu Y, Almeida M, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Skeletal inflammation and attenuation of Wnt signaling, Wnt ligand expression, and bone formation in atherosclerotic ApoE-null mice. Am J Physiol Endocrinol Metab. 2016 May 01; 310(9):E762-73.
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Diaz KM, Booth JN, Seals SR, Hooker SP, Sims M, Dubbert PM, Muntner P, Shimbo D. Sedentary behavior and subclinical atherosclerosis in African Americans: cross-sectional analysis of the Jackson heart study. Int J Behav Nutr Phys Act. 2016 Mar 01; 13:31.
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Devabhaktuni S, Mercedes A, Diep J, Ahsan C. Coronary Artery Ectasia-A Review of Current Literature. Curr Cardiol Rev. 2016; 12(4):318-323.
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Dai Y, Condorelli G, Mehta JL. Scavenger receptors and non-coding RNAs: relevance in atherogenesis. Cardiovasc Res. 2016 Jan 01; 109(1):24-33.
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Shukla AM, Bose C, Karaduta OK, Apostolov EO, Kaushal GP, Fahmi T, Segal MS, Shah SV. Impact of Hydroxychloroquine on Atherosclerosis and Vascular Stiffness in the Presence of Chronic Kidney Disease. PLoS One. 2015; 10(9):e0139226.
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Mathur P, Ding Z, Saldeen T, Mehta JL. Tocopherols in the Prevention and Treatment of Atherosclerosis and Related Cardiovascular Disease. Clin Cardiol. 2015 Sep; 38(9):570-6.
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Mathur P, Ostadal B, Romeo F, Mehta JL. Gender-Related Differences in Atherosclerosis. Cardiovasc Drugs Ther. 2015 Aug; 29(4):319-27.
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Cao M, Theus SA, Straub KD, Figueroa JA, Mirandola L, Chiriva-Internati M, Hermonat PL. AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet. J Transl Med. 2015 Jul 18; 13:235.
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Hodis HN, Mack WJ, Shoupe D, Azen SP, Stanczyk FZ, Hwang-Levine J, Budoff MJ, Henderson VW. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause. 2015 Apr; 22(4):391-401.
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Ng HP, Zhu X, Harmon EY, Lennartz MR, Nagarajan S. Reduced Atherosclerosis in apoE-inhibitory Fc?RIIb-Deficient Mice Is Associated With Increased Anti-Inflammatory Responses by T Cells and Macrophages. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1101-12.
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Shah SV, Shukla AM, Bose C, Basnakian AG, Rajapurkar M. Recent advances in understanding the pathogenesis of atherosclerosis in CKD patients. J Ren Nutr. 2015 Mar; 25(2):205-8.
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Zhu H, Cao M, Figueroa JA, Cobos E, Uretsky BF, Chiriva-Internati M, Hermonat PL. AAV2/8-hSMAD3 gene delivery attenuates aortic atherogenesis, enhances Th2 response without fibrosis, in LDLR-KO mice on high cholesterol diet. J Transl Med. 2014 Sep 20; 12:252.
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Kaynar AM, Yende S, Zhu L, Frederick DR, Chambers R, Burton CL, Carter M, Stolz DB, Agostini B, Gregory AD, Nagarajan S, Shapiro SD, Angus DC. Effects of intra-abdominal sepsis on atherosclerosis in mice. Crit Care. 2014 Sep 03; 18(5):469.
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Paixao AR, Ayers CR, Berry JD, de Lemos JA, Khera A. Atherosclerotic cardiovascular disease prevention: a comparison between the third adult treatment panel and the new 2013 Treatment of Blood Cholesterol Guidelines. Circ Cardiovasc Qual Outcomes. 2014 Sep; 7(5):778-9.
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Zhu X, Ng HP, Lai YC, Craigo JK, Nagilla PS, Raghani P, Nagarajan S. Scavenger receptor function of mouse Fc? receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice. J Immunol. 2014 Sep 01; 193(5):2483-95.
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Dai Y, Dai D, Wang X, Ding Z, Li C, Mehta JL. GLP-1 agonists inhibit ox-LDL uptake in macrophages by activating protein kinase A. J Cardiovasc Pharmacol. 2014 Jul; 64(1):47-52.
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Ding Z, Liu S, Wang X, Dai Y, Khaidakov M, Deng X, Fan Y, Xiang D, Mehta JL. LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis. Cardiovasc Res. 2014 Sep 01; 103(4):619-28.
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Zhu H, Cao M, Mirandola L, Figueroa JA, Cobos E, Chiriva-Internati M, Hermonat PL. Comparison of efficacy of the disease-specific LOX1- and constitutive cytomegalovirus-promoters in expressing interleukin 10 through adeno-associated virus 2/8 delivery in atherosclerotic mice. PLoS One. 2014; 9(4):e94665.
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St John JA, Henderson VW, Hodis HN, Kono N, McCleary CA, Franke AA, Mack WJ. Associations between urine excretion of isoflavonoids and cognition in postmenopausal women in the Women's Isoflavone Soy Health clinical trial. J Am Geriatr Soc. 2014 Apr; 62(4):629-35.
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Ding Z, Liu S, Wang X, Dai Y, Khaidakov M, Romeo F, Mehta JL. LOX-1, oxidant stress, mtDNA damage, autophagy, and immune response in atherosclerosis. Can J Physiol Pharmacol. 2014 Jul; 92(7):524-30.
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Risimic D, Nikolic D, Simeunovic D, Jakšic V, Cekic S, Milenkovic S. Correlation of atherogenic risk factors with retinal artery occlusion in adults. Med Glas (Zenica). 2014 Feb; 11(1):110-4.
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Tharian B, George N, Turkington J, Caddy GR. Hoarseness and hematemesis: a deadly combination. Am J Gastroenterol. 2014 Feb; 109(2):299-300.
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Xing FY, Neeland IJ, Gore MO, Ayers CR, Paixao AR, Turer AT, Berry JD, Khera A, de Lemos JA, McGuire DK. Association of prediabetes by fasting glucose and/or haemoglobin A1c levels with subclinical atherosclerosis and impaired renal function: observations from the Dallas Heart Study. Diab Vasc Dis Res. 2014 Jan; 11(1):11-8.
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Dai Y, Wang X, Ding Z, Dai D, Mehta JL. DPP-4 inhibitors repress foam cell formation by inhibiting scavenger receptors through protein kinase C pathway. Acta Diabetol. 2014; 51(3):471-8.
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Hong SN, Gona P, Fontes JD, Oyama N, Chan RH, Kenchaiah S, Tsao CW, Yeon SB, Schnabel RB, Keaney JF, O'Donnell CJ, Benjamin EJ, Manning WJ. Atherosclerotic biomarkers and aortic atherosclerosis by cardiovascular magnetic resonance imaging in the Framingham Heart Study. J Am Heart Assoc. 2013 Nov 15; 2(6):e000307.
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Pant S, Deshmukh A, Gurumurthy GS, Pothineni NV, Watts TE, Romeo F, Mehta JL. Inflammation and atherosclerosis--revisited. J Cardiovasc Pharmacol Ther. 2014 Mar; 19(2):170-8.
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Apostolov EO, Ok E, Burns S, Nawaz S, Savenka A, Shah S, Basnakian AG. Carbamylated-oxidized LDL: proatherosclerotic effects on endothelial cells and macrophages. J Atheroscler Thromb. 2013; 20(12):878-92.
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Ding Z, Mizeracki AM, Hu C, Mehta JL. LOX-1 deletion and macrophage trafficking in atherosclerosis. Biochem Biophys Res Commun. 2013 Oct 18; 440(2):210-4.
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Jilka RL. The relevance of mouse models for investigating age-related bone loss in humans. J Gerontol A Biol Sci Med Sci. 2013 Oct; 68(10):1209-17.
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Akkus NI, Beedupalli J. Letter to the editor: severe groin pain associated with loss of flow in internal iliac artery in a female patient. J Invasive Cardiol. 2013 Mar; 25(3):A23-4.
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Pelham CJ, Keen HL, Lentz SR, Sigmund CD. Dominant negative PPAR? promotes atherosclerosis, vascular dysfunction, and hypertension through distinct effects in endothelium and vascular muscle. Am J Physiol Regul Integr Comp Physiol. 2013 May 01; 304(9):R690-701.
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Ding Z, Liu S, Wang X, Khaidakov M, Dai Y, Mehta JL. Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis. Sci Rep. 2013; 3:1077.
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Kipari T, Hadoke PW, Iqbal J, Man TY, Miller E, Coutinho AE, Zhang Z, Sullivan KM, Mitic T, Livingstone DE, Schrecker C, Samuel K, White CI, Bouhlel MA, Chinetti-Gbaguidi G, Staels B, Andrew R, Walker BR, Savill JS, Chapman KE, Seckl JR. 11ß-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis. FASEB J. 2013 Apr; 27(4):1519-31.
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Singla S, Ding Z, Mehta JL. Arterial wall-axon reflex: a potential player in atherosclerosis. Ther Adv Cardiovasc Dis. 2012 Oct; 6(5):181-4.
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Ding Z, Wang X, Khaidakov M, Liu S, Dai Y, Mehta JL. Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells. Biochem Biophys Res Commun. 2012 Sep 14; 426(1):106-11.
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Karlsson FH, Fåk F, Nookaew I, Tremaroli V, Fagerberg B, Petranovic D, Bäckhed F, Nielsen J. Symptomatic atherosclerosis is associated with an altered gut metagenome. Nat Commun. 2012; 3:1245.
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Apostolov EO, Basnakian AG, Ok E, Shah SV. Carbamylated low-density lipoprotein: nontraditional risk factor for cardiovascular events in patients with chronic kidney disease. J Ren Nutr. 2012 Jan; 22(1):134-8.
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Kotliar C, Juncos L, Inserra F, de Cavanagh EM, Chuluyan E, Aquino JB, Hita A, Navari C, Sánchez R. Local and systemic cellular immunity in early renal artery atherosclerosis. Clin J Am Soc Nephrol. 2012 Feb; 7(2):224-30.
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Singla S, Hu C, Mizeracki A, Mehta JL. Decorin in atherosclerosis. Ther Adv Cardiovasc Dis. 2011 Dec; 5(6):305-14.
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Ng HP, Burris RL, Nagarajan S. Attenuated atherosclerotic lesions in apoE-Fc?-chain-deficient hyperlipidemic mouse model is associated with inhibition of Th17 cells and promotion of regulatory T cells. J Immunol. 2011 Dec 01; 187(11):6082-93.
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Yan M, Mehta JL, Hu C. LOX-1 and obesity. Cardiovasc Drugs Ther. 2011 Oct; 25(5):469-76.
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Khaidakov M, Mehta JL. Do atherosclerosis and obesity-associated susceptibility to cancer share causative link to oxLDL and LOX-1? Cardiovasc Drugs Ther. 2011 Oct; 25(5):477-87.
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Mitra S, Goyal T, Mehta JL. Oxidized LDL, LOX-1 and atherosclerosis. Cardiovasc Drugs Ther. 2011 Oct; 25(5):419-29.
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Hermonat PL, Zhu H, Cao M, Mehta JL. LOX-1 transcription. Cardiovasc Drugs Ther. 2011 Oct; 25(5):393-400.
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Lü J, Mehta JL. LOX-1: a critical player in the genesis and progression of myocardial ischemia. Cardiovasc Drugs Ther. 2011 Oct; 25(5):431-40.
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Jiang J, Yan M, Mehta JL, Hu C. Angiogenesis is a link between atherosclerosis and tumorigenesis: role of LOX-1. Cardiovasc Drugs Ther. 2011 Oct; 25(5):461-8.
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Xie C, Kang J, Chen JR, Lazarenko OP, Ferguson ME, Badger TM, Nagarajan S, Wu X. Lowbush blueberries inhibit scavenger receptors CD36 and SR-A expression and attenuate foam cell formation in ApoE-deficient mice. Food Funct. 2011 Oct; 2(10):588-94.
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Xie C, Kang J, Chen JR, Nagarajan S, Badger TM, Wu X. Phenolic acids are in vivo atheroprotective compounds appearing in the serum of rats after blueberry consumption. J Agric Food Chem. 2011 Sep 28; 59(18):10381-7.
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Mitra S, Deshmukh A, Sachdeva R, Lu J, Mehta JL. Oxidized low-density lipoprotein and atherosclerosis implications in antioxidant therapy. Am J Med Sci. 2011 Aug; 342(2):135-42.
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Swaminathan S, Shah SV. Novel inflammatory mechanisms of accelerated atherosclerosis in kidney disease. Kidney Int. 2011 Sep; 80(5):453-63.
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Lu J, Mitra S, Wang X, Khaidakov M, Mehta JL. Oxidative stress and lectin-like ox-LDL-receptor LOX-1 in atherogenesis and tumorigenesis. Antioxid Redox Signal. 2011 Oct 15; 15(8):2301-33.
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Mitra S, Khaidakov M, Lu J, Ayyadevara S, Szwedo J, Wang XW, Chen C, Khaidakov S, Kasula SR, Stone A, Pogribny I, Mehta JL. Prior exposure to oxidized low-density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H506-13.
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Kirkby NS, Low L, Seckl JR, Walker BR, Webb DJ, Hadoke PW. Quantitative 3-dimensional imaging of murine neointimal and atherosclerotic lesions by optical projection tomography. PLoS One. 2011 Feb 17; 6(2):e16906.
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Hsu PI, Lai KH, Liu CP. Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis. Gastroenterology. 2011 Mar; 140(3):791-8.
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Gizard F, Heywood EB, Findeisen HM, Zhao Y, Jones KL, Cudejko C, Post GR, Staels B, Bruemmer D. Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages. Arterioscler Thromb Vasc Biol. 2011 Feb; 31(2):245-52.
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Singh V, Sharma R, Kumar A, Deedwania P. Low high-density lipoprotein cholesterol: current status and future strategies for management. Vasc Health Risk Manag. 2010 Oct 29; 6:979-96.
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Apostolov EO, Ray D, Savenka AV, Shah SV, Basnakian AG. Chronic uremia stimulates LDL carbamylation and atherosclerosis. J Am Soc Nephrol. 2010 Nov; 21(11):1852-7.
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Khaidakov M, Szwedo J, Mitra S, Mehta JL. Angiostatic effects of aspirin in hypoxia-reoxygenation are linked to modulation of TGFß1 signaling. J Cardiovasc Pharmacol Ther. 2011 Mar; 16(1):105-10.
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Burris RL, Xie CH, Thampi P, Wu X, Melnyk SB, Nagarajan S. Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes. Atherosclerosis. 2010 Sep; 212(1):107-15.
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Ding Z, Fan Y, Deng X. Concentration polarization of oxidative modification of low-density lipoproteins: its effect on oxidative modification of low-density lipoprotein uptake and apoptosis of the endothelial cells. ASAIO J. 2010 Sep-Oct; 56(5):468-74.
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Ding Z, Fan Y, Deng X, Sun A, Kang H. 3,3'-Dioctadecylindocarbocyanine-low-density lipoprotein uptake and flow patterns in the rabbit aorta-iliac bifurcation under three perfusion flow conditions. Exp Biol Med (Maywood). 2010 Sep; 235(9):1062-71.
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Khan JA, Cao M, Kang BY, Liu Y, Mehta JL, Hermonat PL. AAV/hSTAT3-gene delivery lowers aortic inflammatory cell infiltration in LDLR KO mice on high cholesterol. Atherosclerosis. 2010 Nov; 213(1):59-66.
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Wu X, Kang J, Xie C, Burris R, Ferguson ME, Badger TM, Nagarajan S. Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression. J Nutr. 2010 Sep; 140(9):1628-32.
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Li D, Patel AR, Klibanov AL, Kramer CM, Ruiz M, Kang BY, Mehta JL, Beller GA, Glover DK, Meyer CH. Molecular imaging of atherosclerotic plaques targeted to oxidized LDL receptor LOX-1 by SPECT/CT and magnetic resonance. Circ Cardiovasc Imaging. 2010 Jul; 3(4):464-72.
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Hakeem A, Bhatti S, Cilingiroglu M. The spectrum of atherosclerotic coronary artery disease in HIV patients. Curr Atheroscler Rep. 2010 Mar; 12(2):119-24.
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