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Hirudins

"Hirudins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.


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This graph shows the total number of publications written about "Hirudins" by people in UAMS Profiles by year, and whether "Hirudins" was a major or minor topic of these publications.
Bar chart showing 15 publications over 14 distinct years, with a maximum of 2 publications in 2014
To see the data from this visualization as text, click here.