Glutamate-Cysteine Ligase
 
																	
																		
																	
																		
																	
																	
																		
																	
																		
																	
																	
																			
																					
	"Glutamate-Cysteine Ligase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				One of the enzymes active in the gamma-glutamyl cycle. It catalyzes the synthesis of gamma-glutamylcysteine from glutamate and cysteine in the presence of ATP with the formation of ADP and orthophosphate. EC 6.3.2.2.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D005721
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						| MeSH Number(s) | 
						
							 D08.811.464.259.850.400 
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						| Concept/Terms | 
						
							Glutamate-Cysteine Ligase- Glutamate-Cysteine Ligase
 - Glutamate Cysteine Ligase
 - Ligase, Glutamate-Cysteine
 - gamma-Glutamyl-Cysteine Synthetase
 - Synthetase, gamma-Glutamyl-Cysteine
 - gamma Glutamyl Cysteine Synthetase
 - Glutamylcysteine Synthetase
 - Synthetase, Glutamylcysteine
 
  
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				Below are MeSH descriptors whose meaning is more general than "Glutamate-Cysteine Ligase".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Glutamate-Cysteine Ligase".
				
			 
		 
	 
 
																				
																					
	
	
		
			
			
					
				This graph shows the total number of publications written about "Glutamate-Cysteine Ligase" by people in UAMS Profiles by year, and whether "Glutamate-Cysteine Ligase" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2016 | 0 | 1 | 1 | 
| 2015 | 1 | 0 | 1 | 
| 2014 | 1 | 0 | 1 | 
| 2013 | 0 | 1 | 1 | 
| 2010 | 1 | 0 | 1 | 
| 2009 | 1 | 0 | 1 | 
| 2008 | 0 | 1 | 1 | 
| 2006 | 1 | 0 | 1 | 
| 2003 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Glutamate-Cysteine Ligase" by people in Profiles over the past ten years.
						
					
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Vargason T, Howsmon DP, Melnyk S, James SJ, Hahn J. Mathematical modeling of the methionine cycle and transsulfuration pathway in individuals with autism spectrum disorder. J Theor Biol. 2017 03 07; 416:28-37.