 Coumarins
"Coumarins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. The various coumarins have a wide range of proposed actions and uses including as ANTICOAGULANTS, pharmaceutical aids, indicators and reagents, photoreactive substances, and ANTINEOPLASTIC AGENTS.
| Descriptor ID |
D003374
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| MeSH Number(s) |
D03.438.150.446 D03.830.219.446
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| Concept/Terms |
Coumarins- Coumarins
- Benzopyran-2-ones
- Benzopyran 2 ones
- Coumarines
- 1,2-Benzo-Pyrones
- 1,2 Benzo Pyrones
- 1,2-Benzopyrones
- 1,2 Benzopyrones
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Below are MeSH descriptors whose meaning is more general than "Coumarins".
Below are MeSH descriptors whose meaning is more specific than "Coumarins".
This graph shows the total number of publications written about "Coumarins" by people in UAMS Profiles by year, and whether "Coumarins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 1999 | 1 | 1 | 2 |
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Below are the most recent publications written about "Coumarins" by people in Profiles over the past ten years.
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Yan NL, Nair R, Chu A, Wilson IA, Johnson KA, Morgan GJ, Kelly JW. Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site. Bioorg Med Chem Lett. 2022 03 15; 60:128571.
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Rama Krishna B, Thummuri D, Naidu VGM, Ramakrishna S, Venkata Mallavadhani U. Synthesis of some novel orcinol based coumarin triazole hybrids with capabilities to inhibit RANKL-induced osteoclastogenesis through NF-?B signaling pathway. Bioorg Chem. 2018 08; 78:94-102.
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Jacobi JL, Yang B, Li X, Menze AK, Laurentz SM, Janle EM, Ferruzzi MG, McCabe GP, Chapple C, Kirchmaier AL. Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin. PLoS One. 2016; 11(2):e0149207.
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Bharate JB, Singh S, Wani A, Sharma S, Joshi P, Khan IA, Kumar A, Vishwakarma RA, Bharate SB. Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump. Org Biomol Chem. 2015 May 21; 13(19):5424-31.
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Gali R, Banothu J, Gondru R, Bavantula R, Velivela Y, Crooks PA. One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies. Bioorg Med Chem Lett. 2015 Jan 01; 25(1):106-12.
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