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Timothy Koscik

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCOM | Peds Neurology Research
Address4301 W Markham
Little Rock AR 72205
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    Collapse Research 
    Collapse research activities and funding
    CC035761     (KOSCIK, TIMOTHY)Sep 1, 2022 - Aug 31, 2023
    UAMS ACHRI Flow Through
    ACRI SAF Recruitment-Koscik
    Role: Principal Investigator

    GR034215     (KOSCIK, TIMOTHY)Aug 1, 2022 - Jul 31, 2023
    UAMS ACHRI Flow Through
    Brain Development and Pre-Speech Function in Infants with Isolated Oral Clefts: Relationship to Anesthesia Exposure and Oxygenation (sub)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Gandy K, Koscik TR, Alexander T, Steinberg JD, Krull KR, van der Plas E. Characterization of brain development with neuroimaging in a female mouse model of chemotherapy treatment of acute lymphoblastic leukemia. Transl Pediatr. 2024 Mar 27; 13(3):408-416. PMID: 38590373.
      View in: PubMed
    2. Gandy K, Sapkota Y, Scoggins MA, Jacola LM, Koscik TR, Hudson MM, Pui CH, Krull KR, van der Plas E. Genetic variants, neurocognitive outcomes, and functional neuroimaging in survivors of childhood acute lymphoblastic leukemia. JNCI Cancer Spectr. 2023 07 03; 7(4). PMID: 37285328.
      View in: PubMed
    3. Koscik TR, van der Plas E, Long JD, Cross S, Gutmann L, Cumming SA, Monckton DG, Shields RK, Magnotta V, Nopoulos PC. Longitudinal changes in white matter as measured with diffusion tensor imaging in adult-onset myotonic dystrophy type 1. Neuromuscul Disord. 2023 08; 33(8):660-669. PMID: 37419717.
      View in: PubMed
    4. Zhang L, Guo Z, Zhang H, van der Plas E, Koscik TR, Nopoulos PC, Sonka M. Assisted annotation in Deep LOGISMOS: Simultaneous multi-compartment 3D MRI segmentation of calf muscles. Med Phys. 2023 Aug; 50(8):4916-4929. PMID: 36750977.
      View in: PubMed
    5. Agostinelli LJ, Seaman SC, Saper CB, Fykstra DP, Hefti MM, Koscik TR, Dlouhy BJ, Bassuk AG. Human Brainstem and Cerebellum Atlas: Chemoarchitecture and Cytoarchitecture Paired to MRI. J Neurosci. 2023 01 11; 43(2):221-239. PMID: 36442999.
      View in: PubMed
    6. Schultz JL, Langbehn DR, Al-Kaylani HM, van der Plas E, Koscik TR, Epping EA, Espe-Pfeifer PB, Martin EP, Moser DJ, Magnotta VA, Nopoulos PC. Longitudinal Clinical and Biological Characteristics in Juvenile-Onset Huntington's Disease. Mov Disord. 2023 01; 38(1):113-122. PMID: 36318082.
      View in: PubMed
    7. Raghuram A, Sanchez S, Wendt L, Cochran S, Ishii D, Osorno C, Bathla G, Koscik TR, Torner J, Hasan D, Samaniego EA. 3D aneurysm wall enhancement is associated with symptomatic presentation. J Neurointerv Surg. 2023 Aug; 15(8):747-752. PMID: 35853699.
      View in: PubMed
    8. Raghuram A, Varon A, Sanchez S, Ishii D, Wu C, Magnotta VA, Hasan DM, Koscik TR, Samaniego EA. Topographical Analysis of Aneurysm Wall Enhancement With 3-Dimensional Mapping. Stroke Vasc Interv Neurol. 2022 Jul; 2(4). PMID: 36061513.
      View in: PubMed
    9. Hamilton MJ, Atalaia A, McLean J, Cumming SA, Evans JJ, Ballantyne B, Jampana R, Longman C, Livingston E, van der Plas E, Koscik T, Nopoulos P, Farrugia ME, Monckton DG. Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1. Neuromuscul Disord. 2022 05; 32(5):377-389. PMID: 35361525.
      View in: PubMed
    10. van der Plas E, Long JD, Koscik TR, Magnotta V, Monckton DG, Cumming SA, Gottschalk AC, Hefti M, Gutmann L, Nopoulos PC. Blood-Based Markers of Neuronal Injury in Adult-Onset Myotonic Dystrophy Type 1. Front Neurol. 2021; 12:791065. PMID: 35126292.
      View in: PubMed
    11. Reasoner EE, van der Plas E, Langbehn DR, Conrad AL, Koscik TR, Epping EA, Magnotta VA, Nopoulos PC. Cortical Features in Child and Adolescent Carriers of Mutant Huntingtin (mHTT). J Huntingtons Dis. 2022; 11(2):173-178. PMID: 35275555.
      View in: PubMed
    12. Benavides A, Bell EF, Conrad AL, Feldman HA, Georgieff MK, Josephson CD, Koscik TR, Stowell SR, Sola-Visner M, Nopoulos P. Sex Differences in the Association of Pretransfusion Hemoglobin Levels with Brain Structure and Function in the Preterm Infant. J Pediatr. 2022 04; 243:78-84.e5. PMID: 34968498.
      View in: PubMed
    13. van der Plas E, Solomon MA, Hopkins L, Koscik T, Schultz J, Brophy PD, Nopoulos PC, Harshman LA. Global and Regional White Matter Fractional Anisotropy in Children with Chronic Kidney Disease. J Pediatr. 2022 03; 242:166-173.e3. PMID: 34758354.
      View in: PubMed
    14. Raghuram A, Varon A, Roa JA, Ishii D, Lu Y, Raghavan ML, Wu C, Magnotta VA, Hasan DM, Koscik TR, Samaniego EA. Semiautomated 3D mapping of aneurysmal wall enhancement with 7T-MRI. Sci Rep. 2021 09 15; 11(1):18344. PMID: 34526579.
      View in: PubMed
    15. Miller JN, Kruger A, Moser DJ, Gutmann L, van der Plas E, Koscik TR, Cumming SA, Monckton DG, Nopoulos PC. Cognitive Deficits, Apathy, and Hypersomnolence Represent the Core Brain Symptoms of Adult-Onset Myotonic Dystrophy Type 1. Front Neurol. 2021; 12:700796. PMID: 34276551.
      View in: PubMed
    16. van der Plas E, Koscik TR, Magnotta V, Cumming SA, Monckton D, Gutmann L, Nopoulos P. Neurocognitive Features of Motor Premanifest Individuals With Myotonic Dystrophy Type 1. Neurol Genet. 2021 Apr; 7(2):e577. PMID: 33912661.
      View in: PubMed
    17. Koscik TR, van der Plas E, Gutmann L, Cumming SA, Monckton DG, Magnotta V, Shields RK, Nopoulos PC. White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden. Sci Rep. 2021 03 01; 11(1):4886. PMID: 33649422.
      View in: PubMed
    18. Koscik TR, Sloat L, van der Plas E, Joers JM, Deelchand DK, Lenglet C, ?z G, Nopoulos PC. Brainstem and striatal volume changes are detectable in under 1 year and predict motor decline in spinocerebellar ataxia type 1. Brain Commun. 2020; 2(2):fcaa184. PMID: 33409488.
      View in: PubMed
    19. Solomon MA, van der Plas E, Langbehn KE, Novak M, Schultz JL, Koscik TR, Conrad AL, Brophy PD, Furth SL, Nopoulos PC, Harshman LA. Early pediatric chronic kidney disease is associated with brain volumetric gray matter abnormalities. Pediatr Res. 2021 02; 89(3):526-532. PMID: 33069166.
      View in: PubMed
    20. Miller JN, van der Plas E, Hamilton M, Koscik TR, Gutmann L, Cumming SA, Monckton DG, Nopoulos PC. Variant repeats within the DMPK CTG expansion protect function in myotonic dystrophy type 1. Neurol Genet. 2020 Oct; 6(5):e504. PMID: 32851192.
      View in: PubMed
    21. Botvinik-Nezer R, Holzmeister F, Camerer CF, Dreber A, Huber J, Johannesson M, Kirchler M, Iwanir R, Mumford JA, Adcock RA, Avesani P, Baczkowski BM, Bajracharya A, Bakst L, Ball S, Barilari M, Bault N, Beaton D, Beitner J, Benoit RG, Berkers RMWJ, Bhanji JP, Biswal BB, Bobadilla-Suarez S, Bortolini T, Bottenhorn KL, Bowring A, Braem S, Brooks HR, Brudner EG, Calderon CB, Camilleri JA, Castrellon JJ, Cecchetti L, Cieslik EC, Cole ZJ, Collignon O, Cox RW, Cunningham WA, Czoschke S, Dadi K, Davis CP, Luca A, Delgado MR, Demetriou L, Dennison JB, Di X, Dickie EW, Dobryakova E, Donnat CL, Dukart J, Duncan NW, Durnez J, Eed A, Eickhoff SB, Erhart A, Fontanesi L, Fricke GM, Fu S, Galv?n A, Gau R, Genon S, Glatard T, Glerean E, Goeman JJ, Golowin SAE, Gonz?lez-Garc?a C, Gorgolewski KJ, Grady CL, Green MA, Guassi Moreira JF, Guest O, Hakimi S, Hamilton JP, Hancock R, Handjaras G, Harry BB, Hawco C, Herholz P, Herman G, Heunis S, Hoffstaedter F, Hogeveen J, Holmes S, Hu CP, Huettel SA, Hughes ME, Iacovella V, Iordan AD, Isager PM, Isik AI, Jahn A, Johnson MR, Johnstone T, Joseph MJE, Juliano AC, Kable JW, Kassinopoulos M, Koba C, Kong XZ, Koscik TR, Kucukboyaci NE, Kuhl BA, Kupek S, Laird AR, Lamm C, Langner R, Lauharatanahirun N, Lee H, Lee S, Leemans A, Leo A, Lesage E, Li F, Li MYC, Lim PC, Lintz EN, Liphardt SW, Losecaat Vermeer AB, Love BC, Mack ML, Malpica N, Marins T, Maumet C, McDonald K, McGuire JT, Melero H, M?ndez Leal AS, Meyer B, Meyer KN, Mihai G, Mitsis GD, Moll J, Nielson DM, Nilsonne G, Notter MP, Olivetti E, Onicas AI, Papale P, Patil KR, Peelle JE, P?rez A, Pischedda D, Poline JB, Prystauka Y, Ray S, Reuter-Lorenz PA, Reynolds RC, Ricciardi E, Rieck JR, Rodriguez-Thompson AM, Romyn A, Salo T, Samanez-Larkin GR, Sanz-Morales E, Schlichting ML, Schultz DH, Shen Q, Sheridan MA, Silvers JA, Skagerlund K, Smith A, Smith DV, Sokol-Hessner P, Steinkamp SR, Tashjian SM, Thirion B, Thorp JN, Tingh?g G, Tisdall L, Tompson SH, Toro-Serey C, Torre Tresols JJ, Tozzi L, Truong V, Turella L, van 't Veer AE, Verguts T, Vettel JM, Vijayarajah S, Vo K, Wall MB, Weeda WD, Weis S, White DJ, Wisniewski D, Xifra-Porxas A, Yearling EA, Yoon S, Yuan R, Yuen KSL, Zhang L, Zhang X, Zosky JE, Nichols TE, Poldrack RA, Schonberg T. Variability in the analysis of a single neuroimaging dataset by many teams. Nature. 2020 06; 582(7810):84-88. PMID: 32483374.
      View in: PubMed
    22. Samaniego EA, Roa JA, Zhang H, Koscik TR, Ortega-Gutierrez S, Bathla G, Sonka M, Derdeyn C, Magnotta VA, Hasan D. Increased contrast enhancement of the parent vessel of unruptured intracranial aneurysms in 7T MR imaging. J Neurointerv Surg. 2020 Oct; 12(10):1018-1022. PMID: 32424006.
      View in: PubMed
    23. Conrad AL, Wermke K, Eisenmann M, Kuhlmann E, Benavides A, Koscik T, Magnotta V. Preliminary evaluation of pre-speech and neurodevelopmental measures in 7-11-week-old infants with isolated oral clefts. Pediatr Res. 2021 01; 89(1):85-90. PMID: 32279071.
      View in: PubMed
    24. Koscik TR, Man V, Jahn A, Lee CH, Cunningham WA. Decomposing the neural pathways in a simple, value-based choice. Neuroimage. 2020 07 01; 214:116764. PMID: 32205252.
      View in: PubMed
    25. Trapp NT, Bruss J, King Johnson M, Uitermarkt BD, Garrett L, Heinzerling A, Wu C, Koscik TR, Ten Eyck P, Boes AD. Reliability of targeting methods in TMS for depression: Beam F3 vs. 5.5 cm. Brain Stimul. 2020 May - Jun; 13(3):578-581. PMID: 32289680.
      View in: PubMed
    26. Trapp NT, Uitermarkt B, King Johnson M, Koscik TR, Garrett L, Heinzerling A, Zanaty M, Holland MT, Howard M, Boes AD. A new device to improve target localization for transcranial magnetic stimulation therapy. Brain Stimul. 2019 Nov - Dec; 12(6):1600-1602. PMID: 31402180.
      View in: PubMed
    27. van der Plas E, Langbehn DR, Conrad AL, Koscik TR, Tereshchenko A, Epping EA, Magnotta VA, Nopoulos PC. Abnormal brain development in child and adolescent carriers of mutant huntingtin. Neurology. 2019 Sep 03; 93(10):e1021-e1030. PMID: 31371571.
      View in: PubMed
    28. Asp EW, Gullickson JT, Warner KA, Koscik TR, Denburg NL, Tranel D. Soft on crime: Patients with ventromedial prefrontal cortex damage allocate reduced third-party punishment to violent criminals. Cortex. 2019 10; 119:33-45. PMID: 31071555.
      View in: PubMed
    29. van der Plas E, Hamilton MJ, Miller JN, Koscik TR, Long JD, Cumming S, Povilaikaite J, Farrugia ME, McLean J, Jampana R, Magnotta VA, Gutmann L, Monckton DG, Nopoulos PC. Brain Structural Features of Myotonic Dystrophy Type 1 and their Relationship with CTG Repeats. J Neuromuscul Dis. 2019; 6(3):321-332. PMID: 31306140.
      View in: PubMed
    30. Cunningham WA, Koscik TR. Balancing Type I and Type II error concerns in fMRI through compartmentalized analysis. Cogn Neurosci. 2017 07; 8(3):147-149. PMID: 28285552.
      View in: PubMed
    31. Melo HL, Koscik TR, Vrantsidis TH, Hathaway G, Cunningham WA. Origins of emotional consciousness. Behav Brain Sci. 2016 Jan; 39:e187. PMID: 28355820.
      View in: PubMed
    32. Sutterer MJ, Koscik TR, Tranel D. Sex-related functional asymmetry of the ventromedial prefrontal cortex in regard to decision-making under risk and ambiguity. Neuropsychologia. 2015 Aug; 75:265-73. PMID: 26111489.
      View in: PubMed
    33. Belfi AM, Koscik TR, Tranel D. Damage to the insula is associated with abnormal interpersonal trust. Neuropsychologia. 2015 May; 71:165-72. PMID: 25846668.
      View in: PubMed
    34. van der Plas E, Koscik TR, Conrad AL, Moser DJ, Nopoulos P. Social motivation in individuals with isolated cleft lip and palate. J Clin Exp Neuropsychol. 2013; 35(5):489-500. PMID: 23634967.
      View in: PubMed
    35. Koscik TR, Tranel D. Abnormal causal attribution leads to advantageous economic decision-making: a neuropsychological approach. J Cogn Neurosci. 2013 Aug; 25(8):1372-82. PMID: 23574584.
      View in: PubMed
    36. Koscik TR, Tranel D. Brain evolution and human neuropsychology: the inferential brain hypothesis. J Int Neuropsychol Soc. 2012 May; 18(3):394-401. PMID: 22459075.
      View in: PubMed
    37. Salinas J, Mills ED, Conrad AL, Koscik T, Andreasen NC, Nopoulos P. Sex differences in parietal lobe structure and development. Gend Med. 2012 Feb; 9(1):44-55. PMID: 22333522.
      View in: PubMed
    38. Koscik TR, Tranel D. The human ventromedial prefrontal cortex is critical for transitive inference. J Cogn Neurosci. 2012 May; 24(5):1191-204. PMID: 22288395.
      View in: PubMed
    39. Koscik TR, Tranel D. The human amygdala is necessary for developing and expressing normal interpersonal trust. Neuropsychologia. 2011 Mar; 49(4):602-11. PMID: 20920512.
      View in: PubMed
    40. Gupta R, Koscik TR, Bechara A, Tranel D. The amygdala and decision-making. Neuropsychologia. 2011 Mar; 49(4):760-6. PMID: 20920513.
      View in: PubMed
    41. Koscik T, Bechara A, Tranel D. Sex-related functional asymmetry in the limbic brain. Neuropsychopharmacology. 2010 Jan; 35(1):340-1. PMID: 20010707.
      View in: PubMed
    42. Magnotta VA, Kim J, Koscik T, Beglinger LJ, Espinso D, Langbehn D, Nopoulos P, Paulsen JS. Diffusion Tensor Imaging in Preclinical Huntington's Disease. Brain Imaging Behav. 2009 Mar 01; 3(1):77-84. PMID: 21415933.
      View in: PubMed
    43. Koscik T, O'Leary D, Moser DJ, Andreasen NC, Nopoulos P. Sex differences in parietal lobe morphology: relationship to mental rotation performance. Brain Cogn. 2009 Apr; 69(3):451-9. PMID: 18980790.
      View in: PubMed
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