 Genes, p53
"Genes, p53" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.
| Descriptor ID |
D016158
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| MeSH Number(s) |
G05.360.340.024.340.375.249.385 G05.360.340.024.340.415.400.385
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| Concept/Terms |
Genes, p53- Genes, p53
- p53 Genes
- Gene, p53
- p53 Gene
- TP53 Genes
- Genes, TP53
- Gene, TP53
- TP53 Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, p53".
Below are MeSH descriptors whose meaning is more specific than "Genes, p53".
This graph shows the total number of publications written about "Genes, p53" by people in UAMS Profiles by year, and whether "Genes, p53" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 | | 2016 | 1 | 2 | 3 | | 2015 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2013 | 0 | 3 | 3 | | 2011 | 3 | 0 | 3 | | 2010 | 2 | 1 | 3 | | 2009 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2005 | 1 | 2 | 3 | | 2004 | 1 | 1 | 2 | | 2002 | 1 | 0 | 1 | | 2001 | 1 | 2 | 3 | | 2000 | 2 | 0 | 2 | | 1999 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 1997 | 4 | 1 | 5 | | 1996 | 1 | 0 | 1 | | 1995 | 3 | 0 | 3 | | 1993 | 1 | 0 | 1 | | 1991 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, p53" by people in Profiles over the past ten years.
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Willis AJ, Indra R, Wohak LE, Sozeri O, Feser K, Mrizova I, Phillips DH, Stiborova M, Arlt VM. The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology. 2018 04 01; 398-399:1-12.
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Kucab JE, Hollstein M, Arlt VM, Phillips DH. Nutlin-3a selects for cells harbouring TP53 mutations. Int J Cancer. 2017 02 15; 140(4):877-887.
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Ashouri A, Sayin VI, Van den Eynden J, Singh SX, Papagiannakopoulos T, Larsson E. Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. Nat Commun. 2016 10 25; 7:13197.
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Weinhold N, Ashby C, Rasche L, Chavan SS, Stein C, Stephens OW, Tytarenko R, Bauer MA, Meissner T, Deshpande S, Patel PH, Buzder T, Molnar G, Peterson EA, van Rhee F, Zangari M, Thanendrarajan S, Schinke C, Tian E, Epstein J, Barlogie B, Davies FE, Heuck CJ, Walker BA, Morgan GJ. Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma. Blood. 2016 09 29; 128(13):1735-44.
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Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts. Mutat Res. 2015 Mar; 773:48-62.
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Kortüm KM, Langer C, Monge J, Bruins L, Egan JB, Zhu YX, Shi CX, Jedlowski P, Schmidt J, Ojha J, Bullinger L, Liebisch P, Kull M, Champion MD, Van Wier S, Ahmann G, Rasche L, Knop S, Fonseca R, Einsele H, Stewart AK, Braggio E. Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease. Br J Haematol. 2015 Feb; 168(4):507-10.
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Zhang W, Nandakumar N, Shi Y, Manzano M, Smith A, Graham G, Gupta S, Vietsch EE, Laughlin SZ, Wadhwa M, Chetram M, Joshi M, Wang F, Kallakury B, Toretsky J, Wellstein A, Yi C. Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma. Sci Signal. 2014 May 06; 7(324):ra42.
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Rahmatallah Y, Emmert-Streib F, Glazko G. Gene Sets Net Correlations Analysis (GSNCA): a multivariate differential coexpression test for gene sets. Bioinformatics. 2014 Feb 01; 30(3):360-8.
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Hunt JL, Barnes L, Lewis JS, Mahfouz ME, Slootweg PJ, Thompson LD, Cardesa A, Devaney KO, Gnepp DR, Westra WH, Rodrigo JP, Woolgar JA, Rinaldo A, Triantafyllou A, Takes RP, Ferlito A. Molecular diagnostic alterations in squamous cell carcinoma of the head and neck and potential diagnostic applications. Eur Arch Otorhinolaryngol. 2014 Feb; 271(2):211-23.
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