beta-Lactamases
"beta-Lactamases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.
Descriptor ID |
D001618
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MeSH Number(s) |
D08.811.277.087.180
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "beta-Lactamases".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactamases".
This graph shows the total number of publications written about "beta-Lactamases" by people in UAMS Profiles by year, and whether "beta-Lactamases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 2 | 2 | 2021 | 0 | 1 | 1 | 2020 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2005 | 1 | 1 | 2 | 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Lactamases" by people in Profiles over the past ten years.
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Satlin MJ, Chen L, Gomez-Simmonds A, Marino J, Weston G, Bhowmick T, Seo SK, Sperber SJ, Kim AC, Eilertson B, Derti S, Jenkins SG, Levi MH, Weinstein MP, Tang YW, Hong T, Juretschko S, Hoffman KL, Walsh TJ, Westblade LF, Uhlemann AC, Kreiswirth BN. Impact of a Rapid Molecular Test for Klebsiella pneumoniae Carbapenemase and Ceftazidime-Avibactam Use on Outcomes After Bacteremia Caused by Carbapenem-Resistant Enterobacterales. Clin Infect Dis. 2022 12 19; 75(12):2066-2075.
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Moon SH, Udaondo Z, Jun SR, Huang E. Cefiderocol heteroresistance in Klebsiella pneumoniae is linked to mutations in the siderophore receptor cirA and ß-lactamase activities. Int J Antimicrob Agents. 2022 09; 60(3):106635.
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Moon SH, Udaondo Z, Li X, Yang X, Jun SR, Huang E. Isolation and characterisation of carbapenemase-producing and polymyxin B-resistant Enterobacter bugandensis from a vegetable. J Glob Antimicrob Resist. 2021 09; 26:264-265.
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Stosic MS, Leangapichart T, Lunha K, Jiwakanon J, Angkititrakul S, Järhult JD, Magnusson U, Sunde M. Novel mcr-3.40 variant co-located with mcr-2.3 and blaCTX-M-63 on an IncHI1B/IncFIB plasmid found in Klebsiella pneumoniae from a healthy carrier in Thailand. J Antimicrob Chemother. 2021 07 15; 76(8):2218-2220.
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Alamarat ZI, Babic J, Tran TT, Wootton SH, Dinh AQ, Miller WR, Hanson B, Wanger A, Gary JL, Arias CA, Pérez N. Long-Term Compassionate Use of Cefiderocol To Treat Chronic Osteomyelitis Caused by Extensively Drug-Resistant Pseudomonas aeruginosa and Extended-Spectrum-ß-Lactamase-Producing Klebsiella pneumoniae in a Pediatric Patient. Antimicrob Agents Chemother. 2020 03 24; 64(4).
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Ngaiganam EP, Pagnier I, Chaalal W, Leangapichart T, Chabou S, Rolain JM, Diene SM. Investigation of urban birds as source of ß-lactamase-producing Gram-negative bacteria in Marseille city, France. Acta Vet Scand. 2019 Oct 31; 61(1):51.
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Ming DK, Otter JA, Ghani R, Brannigan ET, Boonyasiri A, Mookerjee S, Gilchrist M, Holmes AH, Davies F. Clinical risk stratification and antibiotic management of NDM and OXA-48 carbapenemase-producing Enterobacteriaceae bloodstream infections in the UK. J Hosp Infect. 2019 05; 102(1):95-97.
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Tafoukt R, Leangapichart T, Hadjadj L, Bakour S, Diene SM, Rolain JM, Touati A. Characterisation of blaOXA-538, a new variant of blaOXA-48, in Shewanella xiamenensis isolated from river water in Algeria. J Glob Antimicrob Resist. 2018 06; 13:70-73.
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Leangapichart T, Tissot-Dupont H, Raoult D, Memish ZA, Rolain JM, Gautret P. Risk factors for acquisition of CTX-M genes in pilgrims during Hajj 2013 and 2014. J Antimicrob Chemother. 2017 09 01; 72(9):2627-2635.
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Tafoukt R, Touati A, Leangapichart T, Bakour S, Rolain JM. Characterization of OXA-48-like-producing Enterobacteriaceae isolated from river water in Algeria. Water Res. 2017 09 01; 120:185-189.
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Leangapichart T, Gautret P, Griffiths K, Belhouchat K, Memish Z, Raoult D, Rolain JM. Acquisition of a High Diversity of Bacteria during the Hajj Pilgrimage, Including Acinetobacter baumannii with blaOXA-72 and Escherichia coli with blaNDM-5 Carbapenemase Genes. Antimicrob Agents Chemother. 2016 10; 60(10):5942-8.
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Leangapichart T, Dia NM, Olaitan AO, Gautret P, Brouqui P, Rolain JM. Acquisition of Extended-Spectrum ß-Lactamases by Escherichia coli and Klebsiella pneumoniae in Gut Microbiota of Pilgrims during the Hajj Pilgrimage of 2013. Antimicrob Agents Chemother. 2016 05; 60(5):3222-6.
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Vella V, Moore LS, Robotham JV, Davies F, Birgand GJ, Otter JA, Brannigan E, Dyakova E, Knight GM, Mookerjee S, Holmes AH. Isolation demand from carbapenemase-producing Enterobacteriaceae screening strategies based on a West London hospital network. J Hosp Infect. 2016 Oct; 94(2):118-24.
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Al-Bayssari C, Olaitan AO, Leangapichart T, Okdah L, Dabboussi F, Hamze M, Rolain JM. Whole-Genome Sequence of a blaOXA-48-Harboring Raoultella ornithinolytica Clinical Isolate from Lebanon. Antimicrob Agents Chemother. 2016 Apr; 60(4):2548-50.
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Gudeta DD, Bortolaia V, Jayol A, Poirel L, Nordmann P, Guardabassi L. Chromobacterium spp. harbour Ambler class A ß-lactamases showing high identity with KPC. J Antimicrob Chemother. 2016 06; 71(6):1493-6.
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Saunders JC, Young LM, Mahood RA, Jackson MP, Revill CH, Foster RJ, Smith DA, Ashcroft AE, Brockwell DJ, Radford SE. An in vivo platform for identifying inhibitors of protein aggregation. Nat Chem Biol. 2016 Feb; 12(2):94-101.
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Gudeta DD, Pollini S, Docquier JD, Bortolaia V, Rossolini GM, Guardabassi L. Biochemical Characterization of CPS-1, a Subclass B3 Metallo-ß-Lactamase from a Chryseobacterium piscium Soil Isolate. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1869-73.
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Gudeta DD, Bortolaia V, Amos G, Wellington EM, Brandt KK, Poirel L, Nielsen JB, Westh H, Guardabassi L. The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing ß-Lactamases of Potential Clinical Relevance. Antimicrob Agents Chemother. 2016 01; 60(1):151-60.
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Hayden MK, Lin MY, Lolans K, Weiner S, Blom D, Moore NM, Fogg L, Henry D, Lyles R, Thurlow C, Sikka M, Hines D, Weinstein RA. Prevention of colonization and infection by Klebsiella pneumoniae carbapenemase-producing enterobacteriaceae in long-term acute-care hospitals. Clin Infect Dis. 2015 Apr 15; 60(8):1153-61.
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