 Dendritic Cells
"Dendritic Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized cells of the hematopoietic system that have branch-like extensions. They are found throughout the lymphatic system, and in non-lymphoid tissues such as SKIN and the epithelia of the intestinal, respiratory, and reproductive tracts. They trap and process ANTIGENS, and present them to T-CELLS, thereby stimulating CELL-MEDIATED IMMUNITY. They are different from the non-hematopoietic FOLLICULAR DENDRITIC CELLS, which have a similar morphology and immune system function, but with respect to humoral immunity (ANTIBODY PRODUCTION).
| Descriptor ID |
D003713
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| MeSH Number(s) |
A11.066.270 A11.436.270 A15.382.066.270 A15.382.812.260
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| Concept/Terms |
Dendritic Cells- Dendritic Cells
- Cell, Dendritic
- Cells, Dendritic
- Dendritic Cell
Interdigitating Cells- Interdigitating Cells
- Cell, Interdigitating
- Cells, Interdigitating
- Interdigitating Cell
- Interdigitating Dendritic Cells
- Dendritic Cells, Interdigitating
- Cell, Interdigitating Dendritic
- Cells, Interdigitating Dendritic
- Dendritic Cell, Interdigitating
- Interdigitating Dendritic Cell
Plasmacytoid Dendritic Cells- Plasmacytoid Dendritic Cells
- Cell, Plasmacytoid Dendritic
- Cells, Plasmacytoid Dendritic
- Dendritic Cell, Plasmacytoid
- Plasmacytoid Dendritic Cell
- Dendritic Cells, Plasmacytoid
Veiled Cells- Veiled Cells
- Cell, Veiled
- Cells, Veiled
- Veiled Cell
Interstitial Dendritic Cells- Interstitial Dendritic Cells
- Cell, Interstitial Dendritic
- Cells, Interstitial Dendritic
- Dendritic Cell, Interstitial
- Interstitial Dendritic Cell
- Dendritic Cells, Interstitial
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Below are MeSH descriptors whose meaning is more general than "Dendritic Cells".
Below are MeSH descriptors whose meaning is more specific than "Dendritic Cells".
This graph shows the total number of publications written about "Dendritic Cells" by people in UAMS Profiles by year, and whether "Dendritic Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2021 | 1 | 2 | 3 | | 2020 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2017 | 2 | 2 | 4 | | 2016 | 2 | 1 | 3 | | 2015 | 0 | 2 | 2 | | 2014 | 2 | 4 | 6 | | 2013 | 2 | 0 | 2 | | 2012 | 5 | 1 | 6 | | 2011 | 4 | 3 | 7 | | 2010 | 2 | 1 | 3 | | 2009 | 3 | 2 | 5 | | 2008 | 3 | 0 | 3 | | 2007 | 6 | 1 | 7 | | 2006 | 1 | 0 | 1 | | 2005 | 8 | 4 | 12 | | 2004 | 2 | 3 | 5 | | 2003 | 7 | 1 | 8 | | 2002 | 3 | 1 | 4 | | 2001 | 4 | 1 | 5 | | 2000 | 3 | 0 | 3 | | 1999 | 3 | 1 | 4 | | 1998 | 1 | 2 | 3 | | 1991 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Dendritic Cells" by people in Profiles over the past ten years.
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Lin CC, Chang TY, Lu YC, Wu YS, Huang W, Lo WC, Liu GF, Hsu WC, Ohashi PS, Mak TW, Fuh JL, Chen HC, Tarng DC, Chen NJ. TREM-2 mediates dendritic cell-induced NO to suppress Th17 activation and ameliorate chronic kidney diseases. J Mol Med (Berl). 2022 06; 100(6):917-931.
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Safina I, Al Sudani ZAN, Hashoosh A, Darrigues E, Watanabe F, Biris AS, Dings RPM, Bao Vang K. Gold nanorods enhance different immune cells and allow for efficient targeting of CD4+ Foxp3+ Tregulatory cells. PLoS One. 2021; 16(8):e0241882.
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Zhang Y, Yan Y, Meng J, Girotra M, Ramakrishnan S, Roy S. Immune modulation mediated by extracellular vesicles of intestinal organoids is disrupted by opioids. Mucosal Immunol. 2021 07; 14(4):887-898.
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Safina I, Alghazali KM, Childress L, Griffin C, Hashoosh A, Kannarpady G, Watanabe F, Bourdo SE, Dings RPM, Biris AS, Vang KB. Dendritic cell biocompatibility of ether-based urethane films. J Appl Toxicol. 2021 09; 41(9):1456-1466.
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Block MS, Dietz AB, Gustafson MP, Kalli KR, Erskine CL, Youssef B, Vijay GV, Allred JB, Pavelko KD, Strausbauch MA, Lin Y, Grudem ME, Jatoi A, Klampe CM, Wahner-Hendrickson AE, Weroha SJ, Glaser GE, Kumar A, Langstraat CL, Solseth ML, Deeds MC, Knutson KL, Cannon MJ. Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients. Nat Commun. 2020 10 14; 11(1):5173.
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Nguyen HD, Huong PT, Hossack K, Gurshaney S, Ezhakunnel K, Huynh TH, Alvarez AM, Le NT, Luu HN. Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease. J Vis Exp. 2020 03 17; (157).
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Cannon MJ, Block MS, Morehead LC, Knutson KL. The evolving clinical landscape for dendritic cell vaccines and cancer immunotherapy. Immunotherapy. 2019 02; 11(2):75-79.
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Cafri G, Yossef R, Pasetto A, Deniger DC, Lu YC, Parkhurst M, Gartner JJ, Jia L, Ray S, Ngo LT, Jafferji M, Sachs A, Prickett T, Robbins PF, Rosenberg SA. Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients. Nat Commun. 2019 01 25; 10(1):449.
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Tokatlian T, Read BJ, Jones CA, Kulp DW, Menis S, Chang JYH, Steichen JM, Kumari S, Allen JD, Dane EL, Liguori A, Sangesland M, Lingwood D, Crispin M, Schief WR, Irvine DJ. Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. Science. 2019 02 08; 363(6427):649-654.
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Ainola M, Porola P, Takakubo Y, Przybyla B, Kouri VP, Tolvanen TA, Hänninen A, Nordström DC. Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome. Clin Exp Immunol. 2018 03; 191(3):301-310.
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Lamichhane P, Karyampudi L, Shreeder B, Krempski J, Bahr D, Daum J, Kalli KR, Goode EL, Block MS, Cannon MJ, Knutson KL. IL10 Release upon PD-1 Blockade Sustains Immunosuppression in Ovarian Cancer. Cancer Res. 2017 12 01; 77(23):6667-6678.
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Vang KB, Safina I, Darrigues E, Nedosekin D, Nima ZA, Majeed W, Watanabe F, Kannarpady G, Kore RA, Casciano D, Zharov VP, Griffin RJ, Dings RPM, Biris AS. Modifying Dendritic Cell Activation with Plasmonic Nano Vectors. Sci Rep. 2017 07 14; 7(1):5513.
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Ahmed M, Jiao H, Domingo-Gonzalez R, Das S, Griffiths KL, Rangel-Moreno J, Nagarajan UM, Khader SA. Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice. J Leukoc Biol. 2017 06; 101(6):1373-1381.
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Kaur V, Swami A, Shebli A, Shalin S, Veeraputhiran M, Emanuel P, Jethava Y. A rare case of blastic plasmacytoid dendritic cell neoplasm with deletion 7q.31, in the setting of heavy pre-treatment with alkylating chemotherapy. J Oncol Pharm Pract. 2017 Oct; 23(7):552-556.
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Huang YH, Zhang W, Cai H, Li TJ, Li J, Han B, Zhuang JL, Zhu TN, Cai HC, Zhou DB. [CD200/CD200R Expression Levels and Its Significance after Allogeneic Hematopoietic Stem Cell Transplantation]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Jun; 24(3):815-20.
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Li WA, Lu BY, Gu L, Choi Y, Kim J, Mooney DJ. The effect of surface modification of mesoporous silica micro-rod scaffold on immune cell activation and infiltration. Biomaterials. 2016 Mar; 83:249-56.
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Bencherif SA, Warren Sands R, Ali OA, Li WA, Lewin SA, Braschler TM, Shih TY, Verbeke CS, Bhatta D, Dranoff G, Mooney DJ. Injectable cryogel-based whole-cell cancer vaccines. Nat Commun. 2015 Aug 12; 6:7556.
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Huang L, Hinchman M, Mendez S. Coinjection with TLR2 agonist Pam3CSK4 reduces the pathology of leishmanization in mice. PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003546.
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Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ. Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9. Eur J Immunol. 2015 Feb; 45(2):513-24.
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Huang L, Gebreselassie NG, Gagliardo LF, Ruyechan MC, Lee NA, Lee JJ, Appleton JA. Eosinophil-derived IL-10 supports chronic nematode infection. J Immunol. 2014 Oct 15; 193(8):4178-87.
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Goyne HE, Stone PJ, Burnett AF, Cannon MJ. Ovarian tumor ascites CD14+ cells suppress dendritic cell-activated CD4+ T-cell responses through IL-10 secretion and indoleamine 2,3-dioxygenase. J Immunother. 2014 Apr; 37(3):163-9.
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You C, Qian X, He Y, Liu Y, Hermonat PL. [Development of a lung cancer vaccine by transfecting dendritic cells with rAAV/CEA]. Nan Fang Yi Ke Da Xue Xue Bao. 2014 Apr; 34(4):487-91.
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Kaffenberger BH, Lee GL, Tyler K, Chan DV, Jarjour W, Ariza ME, Williams MV, Wong HK. Current and potential immune therapies and vaccines in the management of psoriasis. Hum Vaccin Immunother. 2014; 10(4):876-86.
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Batchu RB, Gruzdyn OV, Moreno-Bost AM, Szmania S, Jayandharan G, Srivastava A, Kolli BK, Weaver DW, van Rhee F, Gruber SA. Efficient lysis of epithelial ovarian cancer cells by MAGE-A3-induced cytotoxic T lymphocytes using rAAV-6 capsid mutant vector. Vaccine. 2014 Feb 12; 32(8):938-43.
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Cannon MJ, Goyne HE, Stone PJ, Macdonald LJ, James LE, Cobos E, Chiriva-Internati M. Modulation of p38 MAPK signaling enhances dendritic cell activation of human CD4+ Th17 responses to ovarian tumor antigen. Cancer Immunol Immunother. 2013 May; 62(5):839-49.
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Coleman CM, Gelais CS, Wu L. Cellular and viral mechanisms of HIV-1 transmission mediated by dendritic cells. Adv Exp Med Biol. 2013; 762:109-30.
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St Gelais C, de Silva S, Amie SM, Coleman CM, Hoy H, Hollenbaugh JA, Kim B, Wu L. SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons. Retrovirology. 2012 Dec 11; 9:105.
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Sawant A, Hensel JA, Chanda D, Harris BA, Siegal GP, Maheshwari A, Ponnazhagan S. Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol. 2012 Nov 01; 189(9):4258-65.
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