 Exodeoxyribonucleases
"Exodeoxyribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of DNA. It includes members of the class EC 3.1.11 that produce 5'-phosphomonoesters as cleavage products.
| Descriptor ID |
D005090
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| MeSH Number(s) |
D08.811.277.352.335.375 D08.811.277.352.365.290
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exodeoxyribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exodeoxyribonucleases".
This graph shows the total number of publications written about "Exodeoxyribonucleases" by people in UAMS Profiles by year, and whether "Exodeoxyribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 | | 2020 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2013 | 3 | 0 | 3 | | 2012 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Exodeoxyribonucleases" by people in Profiles over the past ten years.
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Rogers CM, Kaur H, Swift ML, Raina VB, Zhou S, Kawale AS, Syed S, Kelly KG, Jasper AM, Salunkhe S, Kwon Y, Wang J, Shabestari AB, Daley JM, Sacks A, Gaczynska ME, Osmulski PA, Rawal Y, Tomimatsu N, Gayther SA, Lawrenson K, Burma S, Wasmuth EV, Olsen SK, Zhao W, Hromas R, Libich DS, Mazin AV, Zhou D, Greene EC, Chowdhury D, Sung P. CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade. Science. 2025 May 22; 388(6749):881-888.
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Salunkhe S, Daley JM, Kaur H, Tomimatsu N, Xue C, Raina VB, Jasper AM, Rogers CM, Li W, Zhou S, Mojidra R, Kwon Y, Fang Q, Ji JH, Badamchi Shabestari A, Fitzgerald O, Dinh H, Mukherjee B, Habib AA, Hromas R, Mazin AV, Wasmuth EV, Olsen SK, Libich DS, Zhou D, Zhao W, Greene EC, Burma S, Sung P. Promotion of DNA end resection by BRCA1-BARD1 in homologous recombination. Nature. 2024 Oct; 634(8033):482-491.
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Daley JM, Tomimatsu N, Hooks G, Wang W, Miller AS, Xue X, Nguyen KA, Kaur H, Williamson E, Mukherjee B, Hromas R, Burma S, Sung P. Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions. Nat Commun. 2020 06 18; 11(1):3088.
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Singh A, Pandey M, Nandakumar D, Raney KD, Yin YW, Patel SS. Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles. EMBO J. 2020 03 16; 39(6):e103367.
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Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P. A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection. J Biol Chem. 2018 11 02; 293(44):17061-17069.
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Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH. Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks. J Biol Chem. 2017 01 27; 292(4):1414-1425.
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