 Exodeoxyribonucleases
"Exodeoxyribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of DNA. It includes members of the class EC 3.1.11 that produce 5'-phosphomonoesters as cleavage products.
| Descriptor ID |
D005090
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| MeSH Number(s) |
D08.811.277.352.335.375 D08.811.277.352.365.290
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exodeoxyribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exodeoxyribonucleases".
This graph shows the total number of publications written about "Exodeoxyribonucleases" by people in UAMS Profiles by year, and whether "Exodeoxyribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2013 | 3 | 0 | 3 | | 2012 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Exodeoxyribonucleases" by people in Profiles over the past ten years.
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Daley JM, Tomimatsu N, Hooks G, Wang W, Miller AS, Xue X, Nguyen KA, Kaur H, Williamson E, Mukherjee B, Hromas R, Burma S, Sung P. Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions. Nat Commun. 2020 06 18; 11(1):3088.
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Singh A, Pandey M, Nandakumar D, Raney KD, Yin YW, Patel SS. Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles. EMBO J. 2020 03 16; 39(6):e103367.
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Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P. A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection. J Biol Chem. 2018 11 02; 293(44):17061-17069.
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Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH. Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks. J Biol Chem. 2017 01 27; 292(4):1414-1425.
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Khadka P, Hsu JK, Veith S, Tadokoro T, Shamanna RA, Mangerich A, Croteau DL, Bohr VA. Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities. Mol Cell Biol. 2015 Dec; 35(23):3974-89.
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Maddukuri L, Ketkar A, Eddy S, Zafar MK, Eoff RL. The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa. Nucleic Acids Res. 2014 Oct 29; 42(19):12027-40.
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Popuri V, Hsu J, Khadka P, Horvath K, Liu Y, Croteau DL, Bohr VA. Human RECQL1 participates in telomere maintenance. Nucleic Acids Res. 2014 May; 42(9):5671-88.
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Zhang J, Yang R, Zhou D, Rudolph KL, Meng A, Ju Z. Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells. Stem Cell Res. 2014 Jan; 12(1):250-9.
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Schaetzlein S, Chahwan R, Avdievich E, Roa S, Wei K, Eoff RL, Sellers RS, Clark AB, Kunkel TA, Scharff MD, Edelmann W. Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):E2470-9.
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Yang H, Yung M, Li L, Hoch JA, Ryan CM, Kar UK, Souda P, Whitelegge JP, Miller JH. Evidence that YycJ is a novel 5'-3' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair. DNA Repair (Amst). 2013 May 01; 12(5):334-46.
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