Autistic Disorder
"Autistic Disorder" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-IV)
Descriptor ID |
D001321
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MeSH Number(s) |
F03.550.325.125
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Concept/Terms |
Autistic Disorder- Autistic Disorder
- Disorder, Autistic
- Disorders, Autistic
- Kanner's Syndrome
- Kanner Syndrome
- Kanners Syndrome
- Syndrome, Kanner's
- Autism, Infantile
- Infantile Autism
- Autism
- Autisms
- Autism, Early Infantile
- Early Infantile Autism
- Infantile Autism, Early
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Below are MeSH descriptors whose meaning is more general than "Autistic Disorder".
Below are MeSH descriptors whose meaning is more specific than "Autistic Disorder".
This graph shows the total number of publications written about "Autistic Disorder" by people in UAMS Profiles by year, and whether "Autistic Disorder" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2019 | 4 | 0 | 4 | 2017 | 6 | 3 | 9 | 2016 | 2 | 2 | 4 | 2015 | 4 | 0 | 4 | 2014 | 7 | 0 | 7 | 2013 | 2 | 2 | 4 | 2012 | 5 | 1 | 6 | 2011 | 1 | 0 | 1 | 2010 | 2 | 0 | 2 | 2009 | 4 | 0 | 4 | 2008 | 4 | 0 | 4 | 2007 | 1 | 1 | 2 | 2006 | 3 | 0 | 3 | 2004 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Autistic Disorder" by people in Profiles over the past ten years.
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Ross PJ, Zhang WB, Mok RSF, Zaslavsky K, Deneault E, D'Abate L, Rodrigues DC, Yuen RKC, Faheem M, Mufteev M, Piekna A, Wei W, Pasceri P, Landa RJ, Nagy A, Varga B, Salter MW, Scherer SW, Ellis J. Synaptic Dysfunction in Human Neurons With Autism-Associated Deletions in PTCHD1-AS. Biol Psychiatry. 2020 01 15; 87(2):139-149.
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Sands TT, Miceli F, Lesca G, Beck AE, Sadleir LG, Arrington DK, Schönewolf-Greulich B, Moutton S, Lauritano A, Nappi P, Soldovieri MV, Scheffer IE, Mefford HC, Stong N, Heinzen EL, Goldstein DB, Perez AG, Kossoff EH, Stocco A, Sullivan JA, Shashi V, Gerard B, Francannet C, Bisgaard AM, Tümer Z, Willems M, Rivier F, Vitobello A, Thakkar K, Rajan DS, Barkovich AJ, Weckhuysen S, Cooper EC, Taglialatela M, Cilio MR. Autism and developmental disability caused by KCNQ3 gain-of-function variants. Ann Neurol. 2019 08; 86(2):181-192.
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Frye RE, Shimasaki C. Reliability of the Cunningham Panel. Transl Psychiatry. 2019 04 08; 9(1):129.
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Cogné B, Ehresmann S, Beauregard-Lacroix E, Rousseau J, Besnard T, Garcia T, Petrovski S, Avni S, McWalter K, Blackburn PR, Sanders SJ, Uguen K, Harris J, Cohen JS, Blyth M, Lehman A, Berg J, Li MH, Kini U, Joss S, von der Lippe C, Gordon CT, Humberson JB, Robak L, Scott DA, Sutton VR, Skraban CM, Johnston JJ, Poduri A, Nordenskjöld M, Shashi V, Gerkes EH, Bongers EMHF, Gilissen C, Zarate YA, Kvarnung M, Lally KP, Kulch PA, Daniels B, Hernandez-Garcia A, Stong N, McGaughran J, Retterer K, Tveten K, Sullivan J, Geisheker MR, Stray-Pedersen A, Tarpinian JM, Klee EW, Sapp JC, Zyskind J, Holla ØL, Bedoukian E, Filippini F, Guimier A, Picard A, Busk ØL, Punetha J, Pfundt R, Lindstrand A, Nordgren A, Kalb F, Desai M, Ebanks AH, Jhangiani SN, Dewan T, Coban Akdemir ZH, Telegrafi A, Zackai EH, Begtrup A, Song X, Toutain A, Wentzensen IM, Odent S, Bonneau D, Latypova X, Deb W, Redon S, Bilan F, Legendre M, Troyer C, Whitlock K, Caluseriu O, Murphree MI, Pichurin PN, Agre K, Gavrilova R, Rinne T, Park M, Shain C, Heinzen EL, Xiao R, Amiel J, Lyonnet S, Isidor B, Biesecker LG, Lowenstein D, Posey JE, Denommé-Pichon AS, Férec C, Yang XJ, Rosenfeld JA, Gilbert-Dussardier B, Audebert-Bellanger S, Redon R, Stessman HAF, Nellaker C, Yang Y, Lupski JR, Goldstein DB, Eichler EE, Bolduc F, Bézieau S, Küry S, Campeau PM. Missense Variants in the Histone Acetyltransferase Complex Component Gene TRRAP Cause Autism and Syndromic Intellectual Disability. Am J Hum Genet. 2019 03 07; 104(3):530-541.
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Tanaka AJ, Cho MT, Willaert R, Retterer K, Zarate YA, Bosanko K, Stefans V, Oishi K, Williamson A, Wilson GN, Basinger A, Barbaro-Dieber T, Ortega L, Sorrentino S, Gabriel MK, Anderson IJ, Sacoto MJG, Schnur RE, Chung WK. De novo variants in EBF3 are associated with hypotonia, developmental delay, intellectual disability, and autism. Cold Spring Harb Mol Case Stud. 2017 Nov; 3(6).
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Rose S, Bennuri SC, Murray KF, Buie T, Winter H, Frye RE. Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: A blinded case-control study. PLoS One. 2017; 12(10):e0186377.
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Salter MW, Stevens B. Microglia emerge as central players in brain disease. Nat Med. 2017 Sep 08; 23(9):1018-1027.
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Constantino JN, Kennon-McGill S, Weichselbaum C, Marrus N, Haider A, Glowinski AL, Gillespie S, Klaiman C, Klin A, Jones W. Infant viewing of social scenes is under genetic control and is atypical in autism. Nature. 2017 07 20; 547(7663):340-344.
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Bourke J, Nembhard WN, Wong K, Leonard H. Twenty-Five Year Survival of Children with Intellectual Disability in Western Australia. J Pediatr. 2017 09; 188:232-239.e2.
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Kuhlthau KA, McDonnell E, Coury DL, Payakachat N, Macklin E. Associations of quality of life with health-related characteristics among children with autism. Autism. 2018 10; 22(7):804-813.
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Frye RE, Rose S, Wynne R, Bennuri SC, Blossom S, Gilbert KM, Heilbrun L, Palmer RF. Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines. Sci Rep. 2017 06 30; 7(1):4478.
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Shpyleva S, Melnyk S, Pavliv O, Pogribny I, Jill James S. Overexpression of LINE-1 Retrotransposons in Autism Brain. Mol Neurobiol. 2018 02; 55(2):1740-1749.
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Doshi P, Tilford JM, Ounpraseuth S, Kuo DZ, Payakachat N. Do Insurance Mandates Affect Racial Disparities in Outcomes for Children with Autism? Matern Child Health J. 2017 02; 21(2):351-366.
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Frye RE, Slattery J, Delhey L, Furgerson B, Strickland T, Tippett M, Sailey A, Wynne R, Rose S, Melnyk S, Jill James S, Sequeira JM, Quadros EV. Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial. Mol Psychiatry. 2018 02; 23(2):247-256.
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Homberg JR, Kyzar EJ, Nguyen M, Norton WH, Pittman J, Poudel MK, Gaikwad S, Nakamura S, Koshiba M, Yamanouchi H, Scattoni ML, Ullman JF, Diamond DM, Kaluyeva AA, Parker MO, Klimenko VM, Apryatin SA, Brown RE, Song C, Gainetdinov RR, Gottesman II, Kalueff AV. Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models. Neurosci Biobehav Rev. 2016 Jun; 65:292-312.
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Payakachat N, Tilford JM, Ungar WJ. National Database for Autism Research (NDAR): Big Data Opportunities for Health Services Research and Health Technology Assessment. Pharmacoeconomics. 2016 Feb; 34(2):127-38.
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Frye RE, Cox D, Slattery J, Tippett M, Kahler S, Granpeesheh D, Damle S, Legido A, Goldenthal MJ. Mitochondrial Dysfunction may explain symptom variation in Phelan-McDermid Syndrome. Sci Rep. 2016 Jan 29; 6:19544.
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Tilford JM, Payakachat N, Kuhlthau KA, Pyne JM, Kovacs E, Bellando J, Williams DK, Brouwer WB, Frye RE. Treatment for Sleep Problems in Children with Autism and Caregiver Spillover Effects. J Autism Dev Disord. 2015 Nov; 45(11):3613-23.
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Ewbank MP, von dem Hagen EA, Powell TE, Henson RN, Calder AJ. The effect of perceptual expectation on repetition suppression to faces is not modulated by variation in autistic traits. Cortex. 2016 07; 80:51-60.
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Aman M, Rettiganti M, Nagaraja HN, Hollway JA, McCracken J, McDougle CJ, Tierney E, Scahill L, Arnold LE, Hellings J, Posey DJ, Swiezy NB, Ghuman J, Grados M, Shah B, Vitiello B. Tolerability, Safety, and Benefits of Risperidone in Children and Adolescents with Autism: 21-Month Follow-up After 8-Week Placebo-Controlled Trial. J Child Adolesc Psychopharmacol. 2015 Aug; 25(6):482-93.
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Bellando J, Fussell JJ, Lopez M. Autism Speaks Toolkits: Resources for Busy Physicians. Clin Pediatr (Phila). 2016 Feb; 55(2):171-5.
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Shpyleva S, Ivanovsky S, de Conti A, Melnyk S, Tryndyak V, Beland FA, James SJ, Pogribny IP. Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum. PLoS One. 2014; 9(11):e113712.
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James SJ, Shpyleva S, Melnyk S, Pavliv O, Pogribny IP. Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum. Transl Psychiatry. 2014 Oct 07; 4:e460.
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Ewbank MP, Rhodes G, von dem Hagen EA, Powell TE, Bright N, Stoyanova RS, Baron-Cohen S, Calder AJ. Repetition Suppression in Ventral Visual Cortex Is Diminished as a Function of Increasing Autistic Traits. Cereb Cortex. 2015 Oct; 25(10):3381-93.
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Agrawal M. Use of propranolol for hypersexual behavior in an adolescent with autism. Ann Pharmacother. 2014 Oct; 48(10):1385-8.
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Schaefer GB. Editorial comment: Fraternal twins with autism, severe cognitive deficit, and epilepsy: diagnostic role of chromosomal microarray analysis. Semin Pediatr Neurol. 2014 Jun; 21(2):172.
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Rose S, Frye RE, Slattery J, Wynne R, Tippett M, Melnyk S, James SJ. Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines. Transl Psychiatry. 2014 Apr 01; 4:e377.
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Rose S, Frye RE, Slattery J, Wynne R, Tippett M, Pavliv O, Melnyk S, James SJ. Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort. PLoS One. 2014; 9(1):e85436.
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Uwaydat SH, Ngo E, Warner D. Treatment of severe ocular hypotony by monthly injections of a viscoelastic agent. Clin Exp Ophthalmol. 2014 Sep-Oct; 42(7):693-4.
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Bailey AR, Hou H, Song M, Obregon DF, Portis S, Barger S, Shytle D, Stock S, Mori T, Sanberg PG, Murphy T, Tan J. GFAP expression and social deficits in transgenic mice overexpressing human sAPPa. Glia. 2013 Sep; 61(9):1556-69.
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Huynh PN, Gathright MM, Holmes KJ, Coffey DB. Worsening psychosis after fever of unknown origin in an adolescent boy with autism. J Child Adolesc Psychopharmacol. 2013 Apr; 23(3):224-7.
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James SJ, Shpyleva S, Melnyk S, Pavliv O, Pogribny IP. Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum. Transl Psychiatry. 2013 Feb 19; 3:e232.
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Zarate YA, Dwivedi A, Bartel FO, Bellomo MA, Cathey SS, Champaigne NL, Clarkson LK, Dupont BR, Everman DB, Geer JS, Gordon BC, Lichty AW, Lyons MJ, Rogers RC, Saul RA, Schroer RJ, Skinner SA, Stevenson RE. Clinical utility of the X-chromosome array. . 2013 Jan; 161A(1):120-30.
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Schendel DE, Diguiseppi C, Croen LA, Fallin MD, Reed PL, Schieve LA, Wiggins LD, Daniels J, Grether J, Levy SE, Miller L, Newschaffer C, Pinto-Martin J, Robinson C, Windham GC, Alexander A, Aylsworth AS, Bernal P, Bonner JD, Blaskey L, Bradley C, Collins J, Ferretti CJ, Farzadegan H, Giarelli E, Harvey M, Hepburn S, Herr M, Kaparich K, Landa R, Lee LC, Levenseller B, Meyerer S, Rahbar MH, Ratchford A, Reynolds A, Rosenberg S, Rusyniak J, Shapira SK, Smith K, Souders M, Thompson PA, Young L, Yeargin-Allsopp M. The Study to Explore Early Development (SEED): a multisite epidemiologic study of autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) network. J Autism Dev Disord. 2012 Oct; 42(10):2121-40.
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Hasan KM, Walimuni IS, Frye RE. Global cerebral and regional multimodal neuroimaging markers of the neurobiology of autism: development and cognition. J Child Neurol. 2013 Jul; 28(7):874-85.
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Rose S, Melnyk S, Pavliv O, Bai S, Nick TG, Frye RE, James SJ. Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Transl Psychiatry. 2012 Jul 10; 2:e134.
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Lopez M, Schulz EG, Baroud T, Hudson A, Wilson M. The Arkansas Autism Developmental Disabilities Monitoring (AR ADDM) project: statewide autism surveillance in a rural state. J Ark Med Soc. 2012 Mar; 108(10):220, 222-4.
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Melnyk S, Fuchs GJ, Schulz E, Lopez M, Kahler SG, Fussell JJ, Bellando J, Pavliv O, Rose S, Seidel L, Gaylor DW, James SJ. Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism. J Autism Dev Disord. 2012 Mar; 42(3):367-77.
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Gunn RK, Huentelman MJ, Brown RE. Are Sema5a mutant mice a good model of autism? A behavioral analysis of sensory systems, emotionality and cognition. Behav Brain Res. 2011 Nov 20; 225(1):142-50.
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