 Alkaline Phosphatase
"Alkaline Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
| Descriptor ID |
D000469
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| MeSH Number(s) |
D08.811.277.352.650.035
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkaline Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Alkaline Phosphatase".
This graph shows the total number of publications written about "Alkaline Phosphatase" by people in UAMS Profiles by year, and whether "Alkaline Phosphatase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2013 | 1 | 2 | 3 | | 2012 | 2 | 2 | 4 | | 2011 | 1 | 1 | 2 | | 2010 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2007 | 1 | 2 | 3 | | 2006 | 0 | 3 | 3 | | 2005 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1991 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkaline Phosphatase" by people in Profiles over the past ten years.
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Manolagas SC. Osteocalcin promotes bone mineralization but is not a hormone. PLoS Genet. 2020 06; 16(6):e1008714.
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Szabo SM, Tomazos IC, Petryk A, Powell LC, Donato BMK, Zarate YA, Tiulpakov A, Martos-Moreno GÁ. Frequency and age at occurrence of clinical manifestations of disease in patients with hypophosphatasia: a systematic literature review. Orphanet J Rare Dis. 2019 04 25; 14(1):85.
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Williams DK, Pinzón C, Huggins S, Pryor JH, Falck A, Herman F, Oldeschulte J, Chavez MB, Foster BL, White SH, Westhusin ME, Suva LJ, Long CR, Gaddy D. Genetic engineering a large animal model of human hypophosphatasia in sheep. Sci Rep. 2018 11 16; 8(1):16945.
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Mohan M, Samant RS, Yoon D, Buros AF, Branca A, Montgomery CO, Nicholas R, Suva LJ, Morello R, Thanendrarajan S, Schinke C, Yaccoby S, van Rhee F, Davies FE, Morgan GJ, Zangari M. Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma. J Bone Miner Res. 2017 Jun; 32(6):1261-1266.
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Makil ES, Tang X, Frazier EA, Collins RT. Alkaline Phosphatase: A Biomarker of Cardiac Function in Pediatric Patients. Pediatr Cardiol. 2017 Apr; 38(4):762-769.
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Choudhary D, Kushwaha P, Gautam J, Kumar P, Verma A, Kumar A, Maurya SW, Siddiqui IR, Mishra PR, Maurya R, Trivedi R. Fast and long acting neoflavonoids dalbergin isolated from Dalbergia sissoo heartwood is osteoprotective in ovariectomized model of osteoporosis: Osteoprotective effect of Dalbergin. Biomed Pharmacother. 2016 Oct; 83:942-957.
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Yoo SY, Kim SK, Heo SJ, Koak JY, Lee JH, Park JM. Biochemical Responses of Anodized Titanium Implants with a Poly(lactide-co-glycolide)/Bone Morphogenic Protein-2 Submicron Particle Coating. Part 1: An In Vitro Study. Int J Oral Maxillofac Implants. 2015 May-Jun; 30(3):512-8.
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Swaminathan S, Rosner MH, Okusa MD. Emerging therapeutic targets of sepsis-associated acute kidney injury. Semin Nephrol. 2015 Jan; 35(1):38-54.
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Elam ML, Johnson SA, Hooshmand S, Feresin RG, Payton ME, Gu J, Arjmandi BH. A calcium-collagen chelate dietary supplement attenuates bone loss in postmenopausal women with osteopenia: a randomized controlled trial. J Med Food. 2015 Mar; 18(3):324-31.
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Shim IK, Chung HJ, Jung MR, Nam SY, Lee SY, Lee H, Heo SJ, Lee SJ. Biofunctional porous anodized titanium implants for enhanced bone regeneration. J Biomed Mater Res A. 2014 Oct; 102(10):3639-48.
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Ferreira E, Porter RM, Wehling N, O'Sullivan RP, Liu F, Boskey A, Estok DM, Harris MB, Vrahas MS, Evans CH, Wells JW. Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013 Oct 11; 288(41):29494-505.
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Rentea RM, Liedel JL, Fredrich K, Pritchard K, Oldham KT, Simpson PM, Gourlay DM. Enteral intestinal alkaline phosphatase administration in newborns decreases iNOS expression in a neonatal necrotizing enterocolitis rat model. J Pediatr Surg. 2013 Jan; 48(1):124-8.
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Heard ME, Pabona JM, Clayberger C, Krensky AM, Simmen FA, Simmen RC. The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus. Biol Reprod. 2012 Nov; 87(5):115.
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Rentea RM, Liedel JL, Fredrich K, Welak SR, Pritchard KA, Oldham KT, Simpson PM, Gourlay DM. Intestinal alkaline phosphatase administration in newborns decreases systemic inflammatory cytokine expression in a neonatal necrotizing enterocolitis rat model. J Surg Res. 2012 Oct; 177(2):228-34.
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Zhang J, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Gomez-Acevedo H, Shankar K, Badger TM, Ronis MJ, Chen JR. Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-pubertal rat. PLoS One. 2012; 7(4):e35736.
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Whyte MP, Greenberg CR, Salman NJ, Bober MB, McAlister WH, Wenkert D, Van Sickle BJ, Simmons JH, Edgar TS, Bauer ML, Hamdan MA, Bishop N, Lutz RE, McGinn M, Craig S, Moore JN, Taylor JW, Cleveland RH, Cranley WR, Lim R, Thacher TD, Mayhew JE, Downs M, Millán JL, Skrinar AM, Crine P, Landy H. Enzyme-replacement therapy in life-threatening hypophosphatasia. N Engl J Med. 2012 Mar 08; 366(10):904-13.
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Yang X, Greenhaw J, Shi Q, Su Z, Qian F, Davis K, Mendrick DL, Salminen WF. Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity. Toxicol Sci. 2012 Feb; 125(2):335-44.
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Zangari M, Aujay M, Zhan F, Hetherington KL, Berno T, Vij R, Jagannath S, Siegel D, Keith Stewart A, Wang L, Orlowski RZ, Belch A, Jakubowiak A, Somlo G, Trudel S, Bahlis N, Lonial S, Singhal S, Kukreti V, Tricot G. Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients. Eur J Haematol. 2011 Jun; 86(6):484-7.
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