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Mourani, Peter

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research overview

My overall research focus has been the identification of mechanisms and biomarkers of acute lung disease in critically ill neonates, infants, and children. Specifically, I have had two research foci: 1) Developmental lung and lung vascular disease in infants who are born extremely premature; and 2) Lower respiratory tract infections, including ventilator-associated-pneumonia in critically ill children requiring mechanical ventilator support. While seemingly disparate topics, these two foci have capitalized on the breadth of my training as both a pulmonologist and critical care physician and collaboration with multi-disciplinary scientific teams to obtain a consistent level of funded projects (including NIH R and U mechanisms) and produce impactful results. In addition to serving as principal investigator (PI) for funded projects in these focused areas, I serve as the site PI and Steering Committee member for the prestigious NICHD supported Collaborative Pediatric Critical Care Research Network (CPCCRN), which performs meaningful clinical research in the field of pediatric critical illness and injury. I am a key member of the team that designed the Personalized Immunomodulation in Pediatric Sepsis-induced MODS (PRECISE) for the upcoming cycle of CPCCRN, which will be among the first personalized medicine trials in pediatric critical care.

One or more keywords matched the following items that are connected to Mourani, Peter

Item Type	Name
Concept	Cerebral Arterial Diseases
Concept	Chronic Disease
Concept	Communicable Diseases
Concept	Cardiovascular Diseases
Concept	Peripheral Vascular Diseases
Concept	Disease Progression
Concept	Diseases in Twins
Concept	Vascular Diseases
Concept	Heart Diseases
Concept	Lung Diseases
Concept	Nervous System Diseases
Concept	Respiratory Tract Diseases
Concept	Genetic Predisposition to Disease
Grant	Genetic Basis for Impaired Angiogenic Signaling in BPD
Grant	The Microbiome, Virome and Host Responses Preceding Ventilator-Associated Pneumon
Grant	Integrated Host/Microbe Metagenomics to Improve Lower Respiratory Tract Infection Diagnosis in Critically Ill Children
Grant	Collaborative Network Study of Airway Microbiome and Host Responses in Pediatric Respiratory Failure
Grant	Pathogenetic Mechanisms of Brochopulmonary Dysplasia
Grant	Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature
Academic Article	Proteomic Profiles Associated with Early Echocardiogram Evidence of Pulmonary Vascular Disease in Preterm Infants.
Academic Article	Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness.
Academic Article	Prone positioning in children with respiratory failure because of coronavirus disease 2019.
Academic Article	Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond.
Academic Article	Genomic Insights into Respiratory Outcomes after Preterm Birth.
Academic Article	Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia.
Academic Article	Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia.
Academic Article	Delirium is a Common and Early Finding in Patients in the Pediatric Cardiac Intensive Care Unit.
Academic Article	Left ventricular diastolic dysfunction in bronchopulmonary dysplasia.
Academic Article	Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease.
Academic Article	Early angiogenic proteins associated with high risk for bronchopulmonary dysplasia and pulmonary hypertension in preterm infants.
Academic Article	Antenatal Determinants of Bronchopulmonary Dysplasia and Late Respiratory Disease in Preterm Infants.
Academic Article	Addressing the challenges of phenotyping pediatric pulmonary vascular disease.
Academic Article	Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung disease.
Academic Article	Early Pulmonary Vascular Disease in Preterm Infants Is Associated with Late Respiratory Outcomes in Childhood.
Academic Article	Cardiac findings and long-term thromboembolic outcomes following pulmonary embolism in children: a combined retrospective-prospective inception cohort study.
Academic Article	Bronchopulmonary dysplasia: a genetic disease.
Academic Article	Reliability of Echocardiographic Indicators of Pulmonary Vascular Disease in Preterm Infants at Risk for Bronchopulmonary Dysplasia.
Academic Article	Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke.
Academic Article	Application of the New Centers for Disease Control and Prevention Surveillance Criteria for Ventilator-Associated Events to a Cohort of PICU Patients Identifies Different Patients Compared With the Previous Definition and Physician Diagnosis.
Academic Article	Scope and impact of early and late preterm infants admitted to the PICU with respiratory illness.
Academic Article	Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.
Academic Article	Identifying Long-Term Morbidities and Health Trajectories After Prolonged Mechanical Ventilation in Children Using State All Payer Claims Data.
Academic Article	Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival With Favorable Neurologic Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial.
Academic Article	DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents.
Academic Article	Survival With Favorable Neurologic Outcome and Quality of Cardiopulmonary Resuscitation Following In-Hospital Cardiac Arrest in Children With Cardiac Disease Compared With Noncardiac Disease.

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