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Search Results to Michael Birrer

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Birrer, Michael

One or more keywords matched the following items that are connected to Birrer, Michael

Item Type	Name
Concept	Proto-Oncogene Proteins
Concept	Proto-Oncogene Proteins c-raf
Concept	Proto-Oncogene Proteins c-fos
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Proto-Oncogene Proteins B-raf
Concept	Proto-Oncogene Proteins c-jun
Concept	Proto-Oncogenes
Concept	Proto-Oncogene Proteins c-myc
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Proto-Oncogene Proteins c-myb
Concept	Proto-Oncogene Proteins c-kit
Concept	Proto-Oncogene Proteins c-met
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Proto-Oncogene Proteins c-akt
Academic Article	Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
Academic Article	p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Academic Article	Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.
Academic Article	Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
Academic Article	Calcineurin activates cytoglobin transcription in hypoxic myocytes.
Academic Article	Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article	EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Academic Article	Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.
Academic Article	Efficacy and safety of imatinib mesylate (Gleevec) and immunohistochemical expression of c-Kit and PDGFR-beta in a Gynecologic Oncology Group Phase Il Trial in women with recurrent or persistent carcinosarcomas of the uterus.
Academic Article	Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
Academic Article	Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.
Academic Article	AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
Academic Article	Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
Academic Article	Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses.
Academic Article	Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
Academic Article	The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
Academic Article	Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.
Academic Article	Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Academic Article	Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Academic Article	Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study.
Academic Article	Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.
Academic Article	The regulation of tumor suppressor genes by oncogenes.
Academic Article	Ovarian cancer: not a borderline issue!
Academic Article	Clinicopathological analysis of c-kit expression in carcinosarcomas and leiomyosarcomas of the uterine corpus.
Academic Article	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
Academic Article	HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
Academic Article	Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression.
Academic Article	Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones.
Academic Article	Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells.
Academic Article	Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells.
Academic Article	A complex pattern of translational initiation and phosphorylation in L-myc proteins.
Academic Article	The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.
Academic Article	L-myc cooperates with ras to transform primary rat embryo fibroblasts.
Academic Article	Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Academic Article	Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.
Academic Article	Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.
Academic Article	Early events in the neoplastic transformation of respiratory epithelium.
Academic Article	Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
Academic Article	The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation.
Academic Article	Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
Academic Article	Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.
Academic Article	Genetic changes in the pathogenesis of lung cancer.
Academic Article	A transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.
Academic Article	The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
Academic Article	Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
Academic Article	Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.
Academic Article	Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Academic Article	Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
Academic Article	Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
Academic Article	The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor.
Academic Article	Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
Academic Article	PACAP stimulates c-fos mRNAs in small cell lung cancer cells.
Academic Article	AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
Academic Article	RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article	JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells.
Academic Article	cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
Academic Article	Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun.
Academic Article	c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
Academic Article	Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
Academic Article	Mechanism of action of a dominant-negative mutant of c-Jun.
Academic Article	Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
Academic Article	Cooperation between retinoic acid and phorbol esters enhances human teratocarcinoma differentiation.
Academic Article	Altered cJUN expression: an early event in human lung carcinogenesis.
Academic Article	Activation and inhibition of the AP-1 complex in human breast cancer cells.
Academic Article	Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Academic Article	The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
Academic Article	Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
Academic Article	Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
Academic Article	Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
Academic Article	Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.
Academic Article	The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
Academic Article	Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
Academic Article	Identification of domains of c-Jun mediating androgen receptor transactivation.
Academic Article	Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
Academic Article	Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
Academic Article	Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
Academic Article	c-Jun triggers apoptosis in human vascular endothelial cells.
Academic Article	TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
Academic Article	Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
Academic Article	Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant.
Academic Article	Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.

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Proto Oncogenes