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Search Results to Michael Birrer

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One or more keywords matched the following items that are connected to Birrer, Michael

Item TypeName
Academic Article Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.
Academic Article Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.
Concept Contractile Proteins
Concept Calcium-Binding Proteins
Concept Microtubule-Associated Proteins
Concept Carrier Proteins
Concept Fungal Proteins
Concept Cytoskeletal Proteins
Concept Microtubule Proteins
Concept Eye Proteins
Concept DNA-Binding Proteins
Concept Membrane Proteins
Concept Oncogene Proteins, Viral
Concept Luminescent Proteins
Concept Proteins
Concept Proto-Oncogene Proteins
Concept Repressor Proteins
Concept Oncogene Proteins
Concept GTP-Binding Proteins
Concept Proto-Oncogene Proteins c-raf
Concept Recombinant Proteins
Concept Proto-Oncogene Proteins c-fos
Concept Proto-Oncogene Proteins p21(ras)
Concept Homeodomain Proteins
Concept Proto-Oncogene Proteins B-raf
Concept Monomeric GTP-Binding Proteins
Concept HSP70 Heat-Shock Proteins
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins c-myc
Concept Adaptor Proteins, Signal Transducing
Concept Wnt Proteins
Concept Apoptosis Regulatory Proteins
Concept Immediate-Early Proteins
Concept Viral Proteins
Concept Smad Proteins
Concept Green Fluorescent Proteins
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins c-myb
Concept 5-Lipoxygenase-Activating Proteins
Concept Saccharomyces cerevisiae Proteins
Concept LIM-Homeodomain Proteins
Concept Heat-Shock Proteins
Concept RNA-Binding Proteins
Concept Extracellular Matrix Proteins
Concept ras Proteins
Concept Tumor Suppressor Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept Retroviridae Proteins, Oncogenic
Concept Oncogene Proteins v-mos
Concept Cell Cycle Proteins
Concept Intercellular Signaling Peptides and Proteins
Concept Proto-Oncogene Proteins c-kit
Concept CCAAT-Enhancer-Binding Proteins
Concept Papillomavirus E7 Proteins
Concept GABA Plasma Membrane Transport Proteins
Concept Proto-Oncogene Proteins c-met
Concept Neoplasm Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept LIM Domain Proteins
Concept Hedgehog Proteins
Concept Proto-Oncogene Proteins c-akt
Concept GPI-Linked Proteins
Concept Nuclear Proteins
Concept Recombinant Fusion Proteins
Concept Oncogene Proteins v-raf
Concept Telomere-Binding Proteins
Academic Article Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Academic Article Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
Academic Article p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Academic Article Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.
Academic Article Ascites analysis by a microfluidic chip allows tumor-cell profiling.
Academic Article Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
Academic Article Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
Academic Article ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.
Academic Article Calcineurin activates cytoglobin transcription in hypoxic myocytes.
Academic Article A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.
Academic Article NORE1A tumor suppressor candidate modulates p21CIP1 via p53.
Academic Article Novel therapeutic targets.
Academic Article Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.
Academic Article Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
Academic Article A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.
Academic Article EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Academic Article Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.
Academic Article Efficacy and safety of imatinib mesylate (Gleevec) and immunohistochemical expression of c-Kit and PDGFR-beta in a Gynecologic Oncology Group Phase Il Trial in women with recurrent or persistent carcinosarcomas of the uterus.
Academic Article Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors.
Academic Article Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.
Academic Article AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
Academic Article TGF-? modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment.
Academic Article Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array.
Academic Article Overexpression of CEACAM6 in borderline and invasive mucinous ovarian neoplasms.
Academic Article Cyclooxygenase-2 expression predicts recurrence of cervical dysplasia following loop electrosurgical excision procedure.
Academic Article Spleen Tyrosine Kinase Confers Paclitaxel Resistance in Ovarian Cancer.
Academic Article Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles.
Academic Article Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
Academic Article Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses.
Academic Article Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
Academic Article The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
Academic Article Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
Academic Article Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.
Academic Article Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.
Academic Article Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Academic Article Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Academic Article The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
Academic Article Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer.
Academic Article RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential.
Academic Article Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Academic Article Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study.
Academic Article CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential.
Academic Article Common variation in Nemo-like kinase is associated with risk of ovarian cancer.
Academic Article Pre-treatment tumor expression of ERCC1 in women with advanced stage epithelial ovarian cancer is not predictive of clinical outcomes: a Gynecologic Oncology Group study.
Academic Article Ovarian cancer risk associated with inherited inflammation-related variants.
Academic Article Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.
Academic Article Ovarian cancer: not a borderline issue!
Academic Article CD157 in ovarian carcinoma: how does it help us?
Academic Article SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK.
Academic Article Clinicopathological analysis of c-kit expression in carcinosarcomas and leiomyosarcomas of the uterine corpus.
Academic Article A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
Academic Article Common variants at 19p13 are associated with susceptibility to ovarian cancer.
Academic Article Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.
Academic Article The origin of ovarian cancer?is it getting clearer?
Academic Article ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Academic Article AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Academic Article HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
Academic Article Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression.
Academic Article Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
Academic Article The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer.
Academic Article Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones.
Academic Article A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.
Academic Article LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
Academic Article Phase 1 Study of Monotherapy with KHK2866, an Anti-Heparin-Binding Epidermal Growth Factor-Like Growth Factor Monoclonal Antibody, in Patients with Advanced Cancer.
Academic Article Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity.
Academic Article Cell cycle and related protein.
Grant The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer
Grant Proteogenomic studies aimed at understanding ovarian tumor responses to agents targeting the DNA damage response and translating this knowledge into clinical benefit
Academic Article Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells.
Academic Article Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells.
Academic Article A complex pattern of translational initiation and phosphorylation in L-myc proteins.
Academic Article The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.
Academic Article L-myc cooperates with ras to transform primary rat embryo fibroblasts.
Academic Article Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Academic Article Characterization of measles polypeptides by monoclonal antibodies.
Academic Article Early events in the neoplastic transformation of respiratory epithelium.
Academic Article Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
Academic Article The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation.
Academic Article Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
Academic Article p53: a frequent target for genetic abnormalities in lung cancer.
Academic Article A transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.
Academic Article The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
Academic Article Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
Academic Article Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
Academic Article Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.
Academic Article Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Academic Article Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
Academic Article Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
Academic Article The inhibitory activity of a transdominant c-jun mutant fused to the ligand binding domain of the estrogen receptor.
Academic Article Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
Academic Article PACAP stimulates c-fos mRNAs in small cell lung cancer cells.
Academic Article Regulation of nuclear oncogenes expressed in lung cancer cell lines.
Academic Article Molecular characterization of adenocarcinoma of the cervix.
Academic Article AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
Academic Article RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cells.
Academic Article Abnormal Fhit expression in malignant and premalignant lesions of the cervix.
Academic Article cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
Academic Article Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun.
Academic Article c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
Academic Article Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
Academic Article Mechanism of action of a dominant-negative mutant of c-Jun.
Academic Article Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
Academic Article Cooperation between retinoic acid and phorbol esters enhances human teratocarcinoma differentiation.
Academic Article Altered cJUN expression: an early event in human lung carcinogenesis.
Academic Article Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
Academic Article Activation and inhibition of the AP-1 complex in human breast cancer cells.
Academic Article Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Academic Article The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
Academic Article Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
Academic Article Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
Academic Article FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
Academic Article Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
Academic Article Alterations in differentiation and apoptosis induced by bufalin in cJun overexpressing U-937 cells.
Academic Article The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
Academic Article Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
Academic Article Identification of domains of c-Jun mediating androgen receptor transactivation.
Academic Article Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
Academic Article Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).
Academic Article Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
Academic Article p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
Academic Article Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
Academic Article Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint.
Academic Article c-Jun triggers apoptosis in human vascular endothelial cells.
Academic Article TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
Academic Article Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis.
Academic Article Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
Academic Article c-Jun activation-dependent tumorigenic transformation induced paradoxically by overexpression or block of S-adenosylmethionine decarboxylase.
Academic Article The role of p27 in endometrial carcinoma.
Academic Article N-(4-hydroxyphenyl) retinamide (4HPR) enhances TRAIL-mediated apoptosis through enhancement of a mitochondrial-dependent amplification loop in ovarian cancer cell lines.
Academic Article RASSF6 is a novel member of the RASSF family of tumor suppressors.
Academic Article Growth inhibition of non-small cell lung cancer cells by AP-1 blockade using a cJun dominant-negative mutant.
Academic Article Simultaneous blockade of AP-1 and phosphatidylinositol 3-kinase pathway in non-small cell lung cancer cells.
Academic Article Identification of LMX1B as a novel oncogene in human ovarian cancer.
Academic Article Phase I study of safety and pharmacokinetics of the anti-MUC16 antibody-drug conjugate DMUC5754A in patients with platinum-resistant ovarian cancer or unresectable pancreatic cancer.
Academic Article Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.
Academic Article LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.
Academic Article DKK1 is a predictive biomarker for response to DKN-01: Results of a phase 2 basket study in women with recurrent endometrial carcinoma.

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