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Search Results to Michael Birrer

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Birrer, Michael

One or more keywords matched the following items that are connected to Birrer, Michael

Item Type	Name
Concept	Germ-Line Mutation
Concept	Mutation
Concept	Point Mutation
Concept	Mutation, Missense
Concept	Mutation Rate
Academic Article	Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.
Academic Article	Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
Academic Article	Inherited Mutations in Women With Ovarian Carcinoma.
Academic Article	Somatic Mosaic Mutations in PPM1D and TP53 in the Blood of Women With Ovarian Carcinoma.
Academic Article	Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.
Academic Article	Phase II, 2-stage, 2-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer.
Academic Article	Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study.
Academic Article	Better therapeutic trials in ovarian cancer.
Academic Article	Dicer, Drosha, and outcomes in patients with ovarian cancer.
Academic Article	Complete Remission Following Pembrolizumab in a Woman with Mismatch Repair-Deficient Endometrial Cancer and a Germline BRCA1 Mutation.
Academic Article	BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
Academic Article	Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
Academic Article	Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.
Academic Article	Early events in the pathogenesis of epithelial ovarian cancer.
Academic Article	Reversible regulation of the transformed phenotype of ornithine decarboxylase- and ras-overexpressing cells by dominant-negative mutants of c-Jun.
Academic Article	Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Academic Article	Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Academic Article	Phase II evaluation of copanlisib, a selective inhibitor of Pi3kca, in patients with persistent or recurrent endometrial carcinoma harboring PIK3CA hotspot mutations: An NRG Oncology study (NRG-GY008).
Academic Article	FGFR2 mutations are rare across histologic subtypes of ovarian cancer.
Academic Article	Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.
Academic Article	The origin of ovarian cancer?is it getting clearer?
Academic Article	Olaparib and a-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial.
Academic Article	Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
Academic Article	p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
Grant	The Use of Transcriptional Factors as Targets and Agents in Carcinogenesis
Grant	The Molecular Genetics of Gynecologic Cancers
Academic Article	Translational research and epithelial carcinogenesis: molecular diagnostic assays now--molecular screening assays soon?
Academic Article	p53: a frequent target for genetic abnormalities in lung cancer.
Academic Article	Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
Academic Article	Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Academic Article	p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.
Academic Article	Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
Academic Article	Regulation of nuclear oncogenes expressed in lung cancer cell lines.
Academic Article	RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article	cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
Academic Article	Complementation analysis of measles virus mutants isolated from persistently infected lymphoblastoid cell lines.
Academic Article	Abnormal expression of the retinoblastoma gene in ovarian neoplasms and correlation to p53 and K-ras mutations.
Academic Article	The molecular genetics of gyn malignancies.
Academic Article	Mechanism of action of a dominant-negative mutant of c-Jun.
Academic Article	Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
Academic Article	Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Academic Article	Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
Academic Article	Use of transcription factors as agents and targets for drug development.
Academic Article	Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
Academic Article	Involvement of activator protein-1 (AP-1) in induction of apoptosis by vitamin E succinate in human breast cancer cells.
Academic Article	The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.
Academic Article	p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
Academic Article	In situ detection of unexpected patterns of mutant p53 gene expression in non-small cell lung cancers.
Academic Article	A SNaPshot of potentially personalized care: Molecular diagnostics in gynecologic cancer.
Academic Article	Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer.
Academic Article	Overall survival and updated progression-free survival outcomes in a randomized phase II study of combination cediranib and olaparib versus olaparib in relapsed platinum-sensitive ovarian cancer.
Academic Article	Corrigendum to "Phase II evaluation of copanlisib, a selective inhibitor of Pi3kca, in patients with persistent or recurrent endometrial carcinoma harboring PIK3CA hotspot mutations: An NRG oncology study (NRG-GY008)" [Gynecol. Oncol. Rep. 31 (2020) 100532].

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